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EP3538140
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EP About this file: EP3538140
| EP3538140 - METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING STEM CELLS PROLIFERATION OR DIFFERENTIATION [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 20.08.2021 Database last updated on 09.09.2024 | |
| Former | Examination is in progress Status updated on 09.03.2020 | ||
| Former | Request for examination was made Status updated on 16.08.2019 | ||
| Former | The international publication has been made Status updated on 18.05.2018 | ||
| Former | unknown Status updated on 12.12.2017 | Most recent event Tooltip | 20.08.2021 | Application deemed to be withdrawn | published on 22.09.2021 [2021/38] | Applicant(s) | For all designated states Institut National de la Santé et de la Recherche Médicale (INSERM) 101, rue de Tolbiac 75013 Paris / FR | For all designated states Universite de Nantes 1 quai de Tourville 44000 Nantes / FR | For all designated states Centre National de la Recherche Scientifique CNRS 3, rue Michel-Ange 75016 Paris / FR | For all designated states Centre Hospitalier Universitaire De Nantes 5 Allée de l'Ile Gloriette 44000 Nantes / FR | For all designated states HCS Pharma 250 Rue Salvadore Allende Bâtiment A 59120 Loos / FR | [N/P] |
| Former [2019/38] | For all designated states Institut National de la Santé et de la Recherche Médicale (INSERM) 101, rue de Tolbiac 75013 Paris / FR | ||
| For all designated states Universite de Nantes 1 quai de Tourville 44000 Nantes / FR | |||
| For all designated states Centre National de la Recherche Scientifique CNRS 3 rue Michel-Ange 75016 Paris / FR | |||
| For all designated states Centre Hospitalier Universitaire De Nantes 5 Allée de l'Ile Gloriette 44000 Nantes / FR | |||
| For all designated states HCS Pharma 250 Rue Salvadore Allende Bâtiment A 59120 Loos / FR | Inventor(s) | 01 /
SI TAYEB, Karim U1087 - INSTITUT DU THORAX 8 Quai Moncousu 44007 Nantes - Cedex 1 / FR | 02 /
IDRISS, Salam Ameican University of Beirut P.O. BOX 11-0236 DTS446 Bliss Street Beirut / LB | 03 /
CARIOU, Bertrand U1087 - INSTITUT DU THORAX 8 Quai Moncousu 44007 Nantes - Cedex 1 / FR | 04 /
ROUDAUT, Méryl U1087 - INSTITUT DU THORAX 8 Quai Moncousu 44007 Nantes - Cedex 1 / FR | 05 /
LE MAY, Cédric U1087 - INSTITUT DU THORAX 8 Quai Moncousu 44007 Nantes - Cedex 1 / FR | 06 /
CAILLAUD, Amandine U1087 - INSTITUT DU THORAX 8 Quai Moncousu 44007 Nantes - Cedex 1 / FR | [2019/38] | Representative(s) | Inserm Transfert PariSanté Campus 10 rue d'Oradour-sur-Glane 75015 Paris / FR | [N/P] |
| Former [2019/38] | Inserm Transfert 7, rue Watt 75013 Paris / FR | Application number, filing date | 17807748.3 | 14.11.2017 | [2019/38] | WO2017EP79190 | Priority number, date | EP20160306485 | 14.11.2016 Original published format: EP 16306485 | [2019/38] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2018087391 | Date: | 17.05.2018 | Language: | EN | [2018/20] | Type: | A1 Application with search report | No.: | EP3538140 | Date: | 18.09.2019 | Language: | EN | The application published by WIPO in one of the EPO official languages on 17.05.2018 takes the place of the publication of the European patent application. | [2019/38] | Search report(s) | International search report - published on: | EP | 17.05.2018 | Classification | IPC: | A61K39/00, A61K31/165, A61K45/06, A61K39/395, A61K31/7105, C12N15/113 | [2019/38] | CPC: |
C12N15/1137 (EP,US);
A61K31/7105 (EP);
A61K45/06 (EP);
A61P35/00 (EP,US);
C12Y304/21061 (US);
A61K2039/505 (EP);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/38] | Title | German: | VERFAHREN UND PHARMAZEUTISCHE ZUSAMMENSETZUNGEN ZUR MODULATION VON STAMMZELLENPROLIFERATION ODER -DIFFERENZIERUNG | [2019/38] | English: | METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATING STEM CELLS PROLIFERATION OR DIFFERENTIATION | [2019/38] | French: | PROCÉDÉS ET COMPOSITIONS PHARMACEUTIQUES POUR MODULER LA PROLIFÉRATION OU LA DIFFÉRENCIATION DE CELLULES SOUCHES | [2019/38] | Entry into regional phase | 14.05.2019 | National basic fee paid | 14.05.2019 | Designation fee(s) paid | 14.05.2019 | Examination fee paid | Examination procedure | 14.05.2019 | Amendment by applicant (claims and/or description) | 14.05.2019 | Examination requested [2019/38] | 14.05.2019 | Date on which the examining division has become responsible | 12.03.2020 | Despatch of a communication from the examining division (Time limit: M06) | 21.09.2020 | Reply to a communication from the examining division | 14.12.2020 | Despatch of a communication from the examining division (Time limit: M04) | 27.04.2021 | Application deemed to be withdrawn, date of legal effect [2021/38] | 20.05.2021 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2021/38] | Fees paid | Renewal fee | 20.11.2019 | Renewal fee patent year 03 | 19.11.2020 | Renewal fee patent year 04 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Cited in | International search | [X]WO2015143072 (WHITEHEAD BIOMEDICAL INST [US]) [X] 1-4 * paragraph [0115] - paragraph [0117] * * claim 70 *; | [X]CN105861679 (Y SHEN BIOINFO CO LTD) [X] 1-4 * the whole document *; | [X] - XIAOWEI SUN ET AL, "Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver", NEOPLASIA, US, (20121201), vol. 14, no. 12, doi:10.1593/neo.121252, ISSN 1476-5586, pages 1122 - IN5, XP055368006 [X] 1-4 * the whole document * DOI: http://dx.doi.org/10.1593/neo.121252 | [X] - MAMATHA BHAT ET AL, "Decreased PCSK9 expression in human hepatocellular carcinoma", BMC GASTROENTEROLOGY, (20151201), vol. 15, no. 1, doi:10.1186/s12876-015-0371-6, XP055368016 [X] 1-4 * the whole document * DOI: http://dx.doi.org/10.1186/s12876-015-0371-6 | by applicant | EP0368684 | US5618829 | US5639757 | US5728868 | US5804396 | US5811097 | US5855887 | WO9932619 | US5981732 | US6046321 | US6051227 | US6100254 | US6107091 | US6127374 | US6207157 | WO0136646 | US6245759 | WO0168836 | US6306874 | US6313138 | US6316444 | US6329380 | US6344459 | US6365354 | US6410323 | US6420382 | US6479512 | US6498165 | US6506559 | US6544988 | US6562818 | US6566135 | US6566131 | WO03042402 | US6573099 | US6586423 | US6586424 | US6682736 | US6740665 | US6794393 | US6875767 | US6927293 | US6958340 | US6984720 | WO2006003388 | WO2006030220 | US2007254295 | WO2008156712 | US7488802 | US7605238 | WO2010036959 | WO2010089411 | US7943743 | WO2011066342 | WO2011082400 | US8008449 | WO2011130354 | WO2011159877 | WO2011161699 | US8168757 | US8217149 | US2014068797 | US8697359 | - Genbank, Database accession no. NM_174936.3, URL: ncbi | - Genbank, Database accession no. NP 777596.2, URL: ncbi | - Genbank, Database accession no. NM_153565.2, URL: ncbi | - Genbank, Database accession no. NP_705793.1, URL: ncbi | - WARD et al., Nature, (19891012), vol. 341, no. 6242, pages 544 - 546 | - HOLT et al., Trends Biotechnol., (20030000), vol. 21, no. 11, pages 484 - 490 | - MITCHELL et al., J Pharmacol Exp Ther., (20140800), vol. 350, no. 2, pages 412 - 24 | - ZETSCHE et al., "Cpfl is a Single RNA-guided Endonuclease of a Class 2 CRISPR-Cas System", Cell, (20150000), vol. 163, pages 1 - 13 | - Genbank, Database accession no. NM 001286350.1, URL: ncbi | - Genbank, Database accession no. NP 001273279.1, URL: ncbi | - Genbank, Database accession no. NM_172826.3, URL: ncbi | - Genbank, Database accession no. NP_766414.3, URL: ncbi | - Agnew Chem Intl. Ed. Engl., (19940000), vol. 33, pages 183 - 186 | - PARDOLL, Nature Reviews Cancer, (20120000), vol. 12, pages 252 - 264 | - BRIGNONE et al., J. Immunol., (20070000), vol. 179, pages 4202 - 4211 | - LOO et al., Clin. Cancer Res., (20120700), no. 18, page 3834 | - FOURCADE et al., J. Exp. Med., (20100000), vol. 207, pages 2175 - 2186 | - SAKUISHI et al., J. Exp. Med., (20100000), vol. 207, pages 2187 - 2194 |