blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP3475285

EP3475285 - MECHANISTIC TARGET OF RAPAMYCIN SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  16.12.2022
Database last updated on 02.09.2024
FormerThe patent has been granted
Status updated on  07.01.2022
FormerGrant of patent is intended
Status updated on  26.08.2021
FormerExamination is in progress
Status updated on  19.03.2021
FormerRequest for examination was made
Status updated on  29.03.2019
FormerThe international publication has been made
Status updated on  29.12.2017
Most recent event   Tooltip03.05.2024Lapse of the patent in a contracting state
New state(s): MK		published on 05.06.2024  [2024/23]
Applicant(s)For all designated states
Suzhou Kintor Pharmaceuticals, Inc.
218 Xinghu Street, Research Building C4-401
Suzhou Industrial Park
Suzhou
Jiangsu 215123 / CN
[2019/18]
Inventor(s)01 / GUO, Chuangxing
4672 Corte Mar Asombrosa
San Diego, CA 92130 / US
02 / TONG, Youzhi
45-30
251 Street
Little Neck, NY 11362 / US
 [2019/18]
Representative(s)Epping - Hermann - Fischer
Patentanwaltsgesellschaft mbH
Schloßschmidstraße 5
80639 München / DE
[2019/18]
Application number, filing date17814538.917.05.2017
[2019/18]
WO2017CN84683
Priority number, dateUS201662354754P25.06.2016         Original published format: US 201662354754 P
[2019/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017219800
Date:28.12.2017
Language:EN
[2017/52]
Type: A1 Application with search report 
No.:EP3475285
Date:01.05.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 28.12.2017 takes the place of the publication of the European patent application.
[2019/18]
Type: B1 Patent specification 
No.:EP3475285
Date:09.02.2022
Language:EN
[2022/06]
Search report(s)International search report - published on:CN28.12.2017
(Supplementary) European search report - dispatched on:EP26.11.2019
ClassificationIPC:C07D487/04, C07D519/00, A61K31/5377, A61P35/00
[2019/18]
CPC:
A61P35/00 (EP,KR); C07D487/04 (EP,KR,US); A61K31/5377 (KR);
C07D519/00 (EP,KR,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/18]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:MECHANISTISCHES TARGET VON RAPAMYCINSIGNALWEGHEMMERN UND THERAPEUTISCHE ANWENDUNGEN DAVON[2019/18]
English:MECHANISTIC TARGET OF RAPAMYCIN SIGNALING PATHWAY INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF[2019/18]
French:CIBLE MÉCANISTE D'INHIBITEURS DE LA VOIE DE SIGNALISATION DE LA RAPAMYCINE ET SES APPLICATIONS THÉRAPEUTIQUES[2019/18]
Entry into regional phase17.01.2019National basic fee paid 
17.01.2019Search fee paid 
17.01.2019Designation fee(s) paid 
17.01.2019Examination fee paid 
Examination proceduredeletedDate on which the examining division has become responsible
17.01.2019Examination requested  [2019/18]
15.06.2020Amendment by applicant (claims and/or description)
19.03.2021Despatch of a communication from the examining division (Time limit: M04)
15.07.2021Reply to a communication from the examining division
27.08.2021Communication of intention to grant the patent
21.12.2021Fee for grant paid
21.12.2021Fee for publishing/printing paid
21.12.2021Receipt of the translation of the claim(s)
Opposition(s)10.11.2022No opposition filed within time limit [2023/03]
Fees paidRenewal fee
22.05.2019Renewal fee patent year 03
31.03.2020Renewal fee patent year 04
27.05.2021Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU17.05.2017
AL09.02.2022
AT09.02.2022
CY09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
IT09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
MK09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IE17.05.2022
LU17.05.2022
BE31.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
[2024/23]
Former [2024/20]HU17.05.2017
AL09.02.2022
AT09.02.2022
CY09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
IT09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IE17.05.2022
LU17.05.2022
BE31.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
Former [2024/18]HU17.05.2017
AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
IT09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IE17.05.2022
LU17.05.2022
BE31.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/35]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
IT09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IE17.05.2022
LU17.05.2022
BE31.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/25]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IE17.05.2022
LU17.05.2022
BE31.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/20]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IE17.05.2022
LU17.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/10]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SI09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
LU17.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/09]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
LU17.05.2022
CH31.05.2022
LI31.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/08]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
LU17.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/06]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
MC09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IS09.06.2022
PT09.06.2022
Former [2023/01]AL09.02.2022
AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IS09.06.2022
PT09.06.2022
Former [2022/49]AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SK09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IS09.06.2022
PT09.06.2022
Former [2022/48]AT09.02.2022
CZ09.02.2022
DK09.02.2022
EE09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IS09.06.2022
PT09.06.2022
Former [2022/47]AT09.02.2022
DK09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RO09.02.2022
RS09.02.2022
SE09.02.2022
SM09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IS09.06.2022
PT09.06.2022
Former [2022/46]AT09.02.2022
DK09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RS09.02.2022
SE09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IS09.06.2022
PT09.06.2022
Former [2022/42]AT09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RS09.02.2022
SE09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
IS09.06.2022
PT09.06.2022
Former [2022/39]AT09.02.2022
ES09.02.2022
FI09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RS09.02.2022
SE09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
PT09.06.2022
Former [2022/36]AT09.02.2022
ES09.02.2022
HR09.02.2022
LT09.02.2022
LV09.02.2022
NL09.02.2022
PL09.02.2022
RS09.02.2022
SE09.02.2022
BG09.05.2022
NO09.05.2022
GR10.05.2022
PT09.06.2022
Former [2022/35]ES09.02.2022
HR09.02.2022
LT09.02.2022
NL09.02.2022
RS09.02.2022
SE09.02.2022
BG09.05.2022
NO09.05.2022
PT09.06.2022
Former [2022/34]ES09.02.2022
LT09.02.2022
NL09.02.2022
NO09.05.2022
PT09.06.2022
Former [2022/33]LT09.02.2022
NO09.05.2022
Documents cited:Search   [ ] - No further relevant documents disclosed
International search[X]CN103450204  (SHANGHAI INST MATERIA MEDICA) [X] 1-42 * the abstract, claims 1-11 *;
 [X]CN102675323  (NANJING REMEDIES DRUG RES & DEV CO LTD) [X] 1-42 * the abstract, claims 1-9 *;
 [A]CN102558185  (SHANGHAI INST MATERIA MEDICA) [A] 1-42 * the abstract, claims 1-10 *
 [X]  - DUGAR, S. et al., "Synthesis and evaluation of pyrrolotriazine based molecules as PI3 kinase inhibitors", Bioorganic & Medicinal Chemistry Letters, (20150610), vol. 25, no. 16, pages 3142 - 3146, XP055226049 [X] 1-42

DOI:   http://dx.doi.org/10.1016/j.bmcl.2015.06.007
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.