Extract from the Register of European Patents

EP About this file: EP3475286

EP3475286 - SUBSTITUTED PYRROLO [2, 3-D]PYRIDAZIN-4-ONES AND PYRAZOLO [3, 4-D]PYRIDAZIN-4-ONES AS PROTEIN KINASE INHIBITORS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.02.2026
Database last updated on 28.03.2026
FormerThe patent has been granted
Status updated on  21.02.2025
FormerGrant of patent is intended
Status updated on  06.01.2025
FormerExamination is in progress
Status updated on  01.04.2022
FormerRequest for examination was made
Status updated on  29.03.2019
FormerThe international publication has been made
Status updated on  29.12.2017
Most recent event   Tooltip06.02.2026Lapse of the patent in a contracting state
New state(s): MC
published on 11.03.2026  [2026/11]
06.02.2026No opposition filed within time limitpublished on 11.03.2026  [2026/11]
Applicant(s)For all designated states
Fochon Pharmaceuticals, Ltd.
100 Xingguang Avenue
Renhe Street
New North District
Chongqing 401121 / CN
[2023/25]
Former [2019/18]For all designated states
Shanghai Fochon Pharmaceutical Co., Ltd.
Room 512 Building A No. 1289 Yishan Road
Shanghai 200233 / CN
For all designated states
Fochon Pharmaceuticals, Ltd.
565 Tushan Road
Nanan District
Chongqing
400061 / CN
Inventor(s)01 / ZHAO, Xingdong
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
02 / ZHANG, Weipeng
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
03 / CHEN, Zhifang
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
04 / CHEN, Ling
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
05 / WANG, Xianlong
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
06 / LI, Zhifu
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
07 / TAN, Rui
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
08 / YANG, Lijun
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
09 / TAN, Haohan
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
10 / LIU, Bin
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
11 / RAN, Kai
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
12 / ZOU, Zongyao
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
13 / LIN, Min
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
14 / SUN, Jing
No. 565 Tushan Road
Nan'an District
Chongqing 400061 / CN
15 / WANG, Weibo
62 Sanders Ranch Road
Moraga, CA 94556 / US
 [2019/18]
Representative(s)Haseltine Lake Kempner LLP
One Portwall Square
Portwall Lane
Bristol BS1 6BH / GB
[2025/13]
Former [2019/18]Haseltine Lake LLP
Redcliff Quay 120 Redcliff Street
Bristol BS1 6HU / GB
Application number, filing date17814693.220.06.2017
[2019/18]
WO2017CN89123
Priority number, dateUS201662353535P22.06.2016         Original published format: US 201662353535 P
US201662412768P25.10.2016         Original published format: US 201662412768 P
[2019/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2017219955
Date:28.12.2017
Language:EN
[2017/52]
Type: A1 Application with search report 
No.:EP3475286
Date:01.05.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 28.12.2017 takes the place of the publication of the European patent application.
[2019/18]
Type: B1 Patent specification 
No.:EP3475286
Date:26.03.2025
Language:EN
[2025/13]
Search report(s)International search report - published on:CN28.12.2017
(Supplementary) European search report - dispatched on:EP09.10.2019
ClassificationIPC:C07D487/04, A61K31/519, A61P35/00
[2019/18]
CPC:
C07D487/04 (EP,KR,RU,US); A61K31/5025 (KR,RU); A61P35/00 (EP,KR,RU,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/18]  
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:SUBSTITUIERTE PYRROLO[2,3-D]PYRIDAZIN-4-ONE UND PYRAZOLO[3,4-D]PYRIDAZIN-4-ONE ALS PROTEIN-KINASE-INHIBITOREN[2019/18]
English:SUBSTITUTED PYRROLO [2, 3-D]PYRIDAZIN-4-ONES AND PYRAZOLO [3, 4-D]PYRIDAZIN-4-ONES AS PROTEIN KINASE INHIBITORS[2019/18]
French:UTILISATION DES COMPOSÉS PYRROLO[2,3-D]PYRIDAZIN-4-ONES ET PYRAZOLO[3,4-D]PYRIDAZIN-4-ONES SUBSTITUÉS COMME INHIBITEURS DE PROTÉINES KINASES[2019/18]
Entry into regional phase18.12.2018National basic fee paid 
18.12.2018Search fee paid 
18.12.2018Designation fee(s) paid 
18.12.2018Examination fee paid 
Examination proceduredeletedDate on which the examining division has become responsible
18.12.2018Examination requested  [2019/18]
08.07.2020Amendment by applicant (claims and/or description)
31.03.2022Despatch of a communication from the examining division (Time limit: M04)
29.07.2022Reply to a communication from the examining division
22.11.2023Despatch of a communication from the examining division (Time limit: M04)
18.03.2024Reply to a communication from the examining division
22.05.2024Despatch of a communication from the examining division (Time limit: M04)
23.09.2024Reply to a communication from the examining division
07.01.2025Communication of intention to grant the patent
19.02.2025Fee for grant paid
19.02.2025Fee for publishing/printing paid
19.02.2025Receipt of the translation of the claim(s)
Opposition(s)05.01.2026No opposition filed within time limit [2026/11]
Fees paidRenewal fee
25.06.2019Renewal fee patent year 03
31.03.2020Renewal fee patent year 04
23.06.2021Renewal fee patent year 05
08.04.2022Renewal fee patent year 06
25.05.2023Renewal fee patent year 07
24.05.2024Renewal fee patent year 08
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Lapses during opposition  TooltipCZ26.03.2025
HR26.03.2025
MC26.03.2025
PL26.03.2025
SK26.03.2025
SM26.03.2025
NO26.06.2025
RS26.06.2025
GR27.06.2025
IS26.07.2025
[2026/11]
Former [2026/09]CZ26.03.2025
HR26.03.2025
PL26.03.2025
SK26.03.2025
SM26.03.2025
NO26.06.2025
RS26.06.2025
GR27.06.2025
IS26.07.2025
Former [2025/49]HR26.03.2025
PL26.03.2025
SK26.03.2025
SM26.03.2025
NO26.06.2025
RS26.06.2025
GR27.06.2025
IS26.07.2025
Former [2025/47]HR26.03.2025
PL26.03.2025
SM26.03.2025
NO26.06.2025
RS26.06.2025
GR27.06.2025
Former [2025/46]HR26.03.2025
SM26.03.2025
NO26.06.2025
RS26.06.2025
GR27.06.2025
Former [2025/35]HR26.03.2025
NO26.06.2025
RS26.06.2025
GR27.06.2025
Former [2025/34]HR26.03.2025
NO26.06.2025
RS26.06.2025
Former [2025/33]RS26.06.2025
Documents cited:Search[I] WO2016007185  (ETERNITY BIOSCIENCE INC et al.) [I] 1-15 * claims 1, 35 *
International search[A] WO2014113942  (MERCK SHARP & DOHME et al.) [A] 1-28 * claims 1, 21 *
 [A] WO2014113932  (MERCK SHARP & DOHME et al.) [A] 1-28 * claims 1, 22 *
 [PX] WO2016112637  (HUBEI BIO PHARMACEUTICAL IND TECHNOLOGICAL INST INC et al.) [PX] 1-28 * claims 1 22 50 *
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