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Extract from the Register of European Patents

EP About this file: EP3541826

EP3541826 - METHODS FOR DETECTING DNA MUTATIONS USING MITRA TIP EXTRACTION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.08.2024
Database last updated on 11.09.2024
FormerThe patent has been granted
Status updated on  25.08.2023
FormerGrant of patent is intended
Status updated on  18.04.2023
FormerExamination is in progress
Status updated on  13.08.2021
FormerRequest for examination was made
Status updated on  23.08.2019
FormerThe international publication has been made
Status updated on  25.05.2018
Most recent event   Tooltip02.08.2024No opposition filed within time limitpublished on 04.09.2024  [2024/36]
Applicant(s)For all designated states
Quest Diagnostics Investments LLC
500 Plaza Drive
Secaucus, NJ 07094 / US
[2019/39]
Inventor(s)01 / SANDERS, Heather
33608 Ortega Highway
San Juan Capistrano, California 92675 / US
02 / CLARKE, Nigel J.
2029 Rancho Corte
Vista, California 92084 / US
 [2019/39]
Representative(s)Hoffmann Eitle
Patent- und Rechtsanwälte PartmbB
Arabellastraße 30
81925 München / DE
[2019/39]
Application number, filing date17871115.613.11.2017
[2019/39]
WO2017US61316
Priority number, dateUS201662422334P15.11.2016         Original published format: US 201662422334 P
[2019/39]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018093724
Date:24.05.2018
Language:EN
[2018/21]
Type: A1 Application with search report 
No.:EP3541826
Date:25.09.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 24.05.2018 takes the place of the publication of the European patent application.
[2019/39]
Type: B1 Patent specification 
No.:EP3541826
Date:27.09.2023
Language:EN
[2023/39]
Search report(s)International search report - published on:US24.05.2018
(Supplementary) European search report - dispatched on:EP24.07.2020
ClassificationIPC:C07H21/00, C07H21/04, C12N5/07, C12N5/10, C12N9/16
[2019/39]
CPC:
C12Q1/6886 (EP,US); C12N15/1058 (US); C12N15/1065 (US);
C12Q1/6806 (EP,US); G01N33/4875 (EP,US); G01N33/49 (EP,US);
G01N33/5308 (EP,US); G01N33/533 (US); C12Q2527/125 (US);
C12Q2600/112 (US); C12Q2600/118 (US); C12Q2600/156 (EP,US);
C12Q2600/16 (EP,US) (-)
C-Set:
C12Q1/6806, C12Q2527/125 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/39]
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TitleGerman:VERFAHREN ZUM NACHWEIS VON DNA-MUTATIONEN MITTELS MITRASPITZENEXTRAKTION[2019/39]
English:METHODS FOR DETECTING DNA MUTATIONS USING MITRA TIP EXTRACTION[2019/39]
French:PROCÉDÉS DE DÉTECTION DE MUTATIONS D'ADN À L'AIDE D'UNE EXTRACTION DE POINTE MITRA[2019/39]
Entry into regional phase14.06.2019National basic fee paid 
14.06.2019Search fee paid 
14.06.2019Designation fee(s) paid 
14.06.2019Examination fee paid 
Examination procedure14.06.2019Examination requested  [2019/39]
22.02.2021Amendment by applicant (claims and/or description)
17.08.2021Despatch of a communication from the examining division (Time limit: M04)
16.12.2021Reply to a communication from the examining division
19.04.2023Communication of intention to grant the patent
14.08.2023Fee for grant paid
14.08.2023Fee for publishing/printing paid
14.08.2023Receipt of the translation of the claim(s)
Divisional application(s)EP23199409.6   Application refused  : 12.02.2024
Opposition(s)28.06.2024No opposition filed within time limit [2024/36]
Fees paidRenewal fee
14.11.2019Renewal fee patent year 03
13.11.2020Renewal fee patent year 04
19.10.2021Renewal fee patent year 05
13.10.2022Renewal fee patent year 06
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT27.09.2023
CZ27.09.2023
DK27.09.2023
EE27.09.2023
ES27.09.2023
FI27.09.2023
HR27.09.2023
IT27.09.2023
LT27.09.2023
LV27.09.2023
MC27.09.2023
NL27.09.2023
PL27.09.2023
RO27.09.2023
RS27.09.2023
SE27.09.2023
SK27.09.2023
SM27.09.2023
LU13.11.2023
CH30.11.2023
NO27.12.2023
GR28.12.2023
IS27.01.2024
PT29.01.2024
[2024/34]
Former [2024/33]AT27.09.2023
CZ27.09.2023
DK27.09.2023
EE27.09.2023
ES27.09.2023
FI27.09.2023
HR27.09.2023
IT27.09.2023
LT27.09.2023
LV27.09.2023
MC27.09.2023
NL27.09.2023
PL27.09.2023
RO27.09.2023
RS27.09.2023
SE27.09.2023
SK27.09.2023
SM27.09.2023
NO27.12.2023
GR28.12.2023
IS27.01.2024
PT29.01.2024
Former [2024/32]AT27.09.2023
CZ27.09.2023
EE27.09.2023
ES27.09.2023
FI27.09.2023
HR27.09.2023
IT27.09.2023
LT27.09.2023
LV27.09.2023
MC27.09.2023
NL27.09.2023
PL27.09.2023
RO27.09.2023
RS27.09.2023
SE27.09.2023
SK27.09.2023
SM27.09.2023
NO27.12.2023
GR28.12.2023
IS27.01.2024
PT29.01.2024
Former [2024/26]AT27.09.2023
CZ27.09.2023
EE27.09.2023
ES27.09.2023
FI27.09.2023
HR27.09.2023
IT27.09.2023
LT27.09.2023
LV27.09.2023
NL27.09.2023
PL27.09.2023
RO27.09.2023
RS27.09.2023
SE27.09.2023
SK27.09.2023
SM27.09.2023
NO27.12.2023
GR28.12.2023
IS27.01.2024
PT29.01.2024
Former [2024/25]AT27.09.2023
CZ27.09.2023
EE27.09.2023
ES27.09.2023
FI27.09.2023
HR27.09.2023
LT27.09.2023
LV27.09.2023
NL27.09.2023
PL27.09.2023
RO27.09.2023
RS27.09.2023
SE27.09.2023
SK27.09.2023
SM27.09.2023
NO27.12.2023
GR28.12.2023
IS27.01.2024
PT29.01.2024
Former [2024/23]AT27.09.2023
CZ27.09.2023
EE27.09.2023
ES27.09.2023
FI27.09.2023
HR27.09.2023
LT27.09.2023
LV27.09.2023
NL27.09.2023
RO27.09.2023
RS27.09.2023
SE27.09.2023
SK27.09.2023
SM27.09.2023
NO27.12.2023
GR28.12.2023
IS27.01.2024
PT29.01.2024
Former [2024/20]FI27.09.2023
HR27.09.2023
LT27.09.2023
LV27.09.2023
NL27.09.2023
RS27.09.2023
SE27.09.2023
SM27.09.2023
NO27.12.2023
GR28.12.2023
IS27.01.2024
Former [2024/14]FI27.09.2023
HR27.09.2023
LT27.09.2023
LV27.09.2023
NL27.09.2023
RS27.09.2023
SE27.09.2023
NO27.12.2023
GR28.12.2023
Former [2024/10]FI27.09.2023
HR27.09.2023
LT27.09.2023
LV27.09.2023
RS27.09.2023
SE27.09.2023
NO27.12.2023
GR28.12.2023
Former [2024/09]FI27.09.2023
LT27.09.2023
SE27.09.2023
NO27.12.2023
GR28.12.2023
Former [2024/08]LT27.09.2023
NO27.12.2023
GR28.12.2023
Documents cited:Search[XI]WO2013067520  (RUDGE JAMES [US], et al) [X] 13 * the whole document * [I] 1-14;
 [XY]WO2016134324  (NEOTERYX LLC [US]) [X] 13 * the whole document * [Y] 1-14;
 [XY]  - HARALD JOHN ET AL, "Procedures for Analysis of Dried Plasma Using Microsampling Devices to Detect Sulfur Mustard-Albumin Adducts for Verification of Poisoning", ANALYTICAL CHEMISTRY, US, (20160815), vol. 88, no. 17, doi:10.1021/acs.analchem.6b02199, ISSN 0003-2700, pages 8787 - 8794, XP055715053 [X] 13 * the whole document * [Y] 1-14

DOI:   http://dx.doi.org/10.1021/acs.analchem.6b02199
 [XY]  - LUO Y ET AL, "Evaluation of two blood microsampling approaches for drug discovery PK studies in rats", BIOANALYSIS 20150901 FUTURE SCIENCE LTD GBR, (20150901), vol. 7, no. 18, ISSN 1757-6180, pages 2345 - 2359, XP009521709 [X] 13 * the whole document * [Y] 1-14

DOI:   http://dx.doi.org/10.4155/bio.15.126
 [XY]  - HOLLY NICHOLLS ET AL, "Evaluation of the Mitra(TM) Micro-sampling Device Against Dried Blood Spot Cards for Measurement of 25-hydroxy Vitamin D3 by LC-MS/MS", CONFERENCE PROCEEDINGS ARTICLE, (20160101), doi:10.13140/rg.2.2.20843.75043, XP055715146 [X] 13 * the whole document * [Y] 1-14

DOI:   http://dx.doi.org/10.13140/rg.2.2.20843.75043
 [XY]  - NEIL SPOONER ET AL, "A device for dried blood microsampling in quantitative bioanalysis: overcoming the issues associated blood hematocrit", BIOANALYSIS, London, UK, (20150401), vol. 7, no. 6, doi:10.4155/bio.14.310, ISSN 1757-6180, pages 653 - 659, XP055493432 [X] 13 * the whole document * [Y] 1-14

DOI:   http://dx.doi.org/10.4155/bio.14.310
 [XI]  - PHILIP DENNIFF ET AL, "Volumetric Absorptive Microsampling: A Dried Sample Collection Technique for Quantitative Bioanalysis", ANALYTICAL CHEMISTRY, US, (20140819), vol. 86, no. 16, doi:10.1021/ac5022562, ISSN 0003-2700, pages 8489 - 8495, XP055263361 [X] 13 * the whole document * [I] 1-14

DOI:   http://dx.doi.org/10.1021/ac5022562
International search[Y]US2011203688  (REED MICHAEL W [US], et al) [Y] 22 * entire document *;
 [Y]US2012192298  (WEINSTEIN EDWARD [US], et al) [Y] 1-3, 20-25 * entire document *;
 [A]WO2016037142  (ZHENG ZHI [US]) [A] 1-3, 20-25, 27-29* entire document *;
 [XY]US2016281166  (BHATTACHARJEE ARINDAM [US], et al) [X] 27-29 * entire document * [Y] 1-3, 20-25;
 [PX]WO2017060271  (UNIV GENT [BE], et al) [PX] 1-3, 20-25, 27-29 * entire document *;
 [PX]WO2017161201  (CYNVENIO BIOSYSTEMS INC [US]) [PX] 1-3, 20-25, 27-29 * entire document *;
 [Y]  - HOUBART et al., "Volumetric Absorptive Microsampling for Hepcidin Peptide Extraction from Whole Blood", LCGC North America, (20160501), vol. 34, no. 5, pages 340 - 347, XP055486510 [Y] 23-25 * . entire document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.