EP3541951 - NON-UNIQUE BARCODES IN A GENOTYPING ASSAY [Right-click to bookmark this link] | Status | The patent has been granted Status updated on 18.10.2024 Database last updated on 19.10.2024 | |
Former | Grant of patent is intended Status updated on 11.06.2024 | ||
Former | Examination is in progress Status updated on 12.08.2021 | ||
Former | Request for examination was made Status updated on 23.08.2019 | ||
Former | The international publication has been made Status updated on 25.05.2018 | Most recent event Tooltip | 18.10.2024 | (Expected) grant | published on 20.11.2024 [2024/47] | Applicant(s) | For all designated states Personal Genome Diagnostics Inc. 2809 Boston Street Suite 503 Baltimore, MD 21224 / US | [2019/39] | Inventor(s) | 01 /
SAUSEN, Mark 2809 Boston Street Suite 503 Baltimore, MD 21224 / US | 02 /
VELCULESCU, Victor 14064 Big Branch Drive Baltimore, MD 21036 / US | 03 /
DIAZ, Luis 5135 Crystal Springs Ellicott City, MD 21043 / US | [2019/39] | Representative(s) | Kilburn & Strode LLP Lacon London 84 Theobalds Road Holborn London WC1X 8NL / GB | [2024/47] |
Former [2019/39] | Cornish, Kristina Victoria Joy, et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL / GB | Application number, filing date | 17872140.3 | 14.11.2017 | [2019/39] | WO2017US61447 | Priority number, date | US201662422355P | 15.11.2016 Original published format: US 201662422355 P | [2019/39] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2018093744 | Date: | 24.05.2018 | Language: | EN | [2018/21] | Type: | A2 Application without search report | No.: | EP3541951 | Date: | 25.09.2019 | Language: | EN | The application published by WIPO in one of the EPO official languages on 24.05.2018 takes the place of the publication of the European patent application. | [2019/39] | Type: | B1 Patent specification | No.: | EP3541951 | Date: | 20.11.2024 | Language: | EN | [2024/47] | Search report(s) | International search report - published on: | KR | 02.08.2018 | (Supplementary) European search report - dispatched on: | EP | 06.05.2020 | Classification | IPC: | C40B40/06, C40B50/06, C12Q1/6827, C12Q1/6874, C12Q1/6886, C12N15/10 | [2024/28] | CPC: |
C12N15/1065 (EP,US);
C12Q1/6827 (EP,US);
C12Q1/6874 (EP,US);
C12Q1/6886 (EP,US);
C12Q2525/161 (US);
C12Q2535/122 (EP,US);
C12Q2535/131 (US);
C12Q2537/143 (US);
C12Q2537/159 (US);
| C-Set: |
C12Q1/6827, C12Q2525/161, C12Q2535/122, C12Q2535/131, C12Q2537/143 (EP);
C12Q1/6874, C12Q2525/161, C12Q2535/122, C12Q2535/131, C12Q2537/143 (EP);
C12Q2535/122, C12Q1/6855, C12Q2537/159, C12Q2563/179 (EP,US)
|
Former IPC [2020/23] | C12Q1/68, C40B40/06, C40B50/06, C12Q1/6827, C12Q1/6874, C12Q1/6886, C12N15/10 | ||
Former IPC [2019/39] | C12Q1/68, G06F19/18, C40B40/06, C40B50/06 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/39] | Extension states | BA | Not yet paid | ME | Not yet paid | Validation states | MA | Not yet paid | MD | Not yet paid | Title | German: | NICHT EINDEUTIGE STRICHCODES IN EINEM GENOTYPISIERUNGSTEST | [2019/39] | English: | NON-UNIQUE BARCODES IN A GENOTYPING ASSAY | [2019/39] | French: | CODES-BARRES NON UNIQUES DANS UN TEST DE GÉNOTYPAGE | [2019/39] | Entry into regional phase | 11.06.2019 | National basic fee paid | 11.06.2019 | Search fee paid | 11.06.2019 | Designation fee(s) paid | 11.06.2019 | Examination fee paid | Examination procedure | 11.06.2019 | Examination requested [2019/39] | 22.01.2021 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 01.04.2021 | Amendment by applicant (claims and/or description) | 11.08.2021 | Despatch of a communication from the examining division (Time limit: M04) | 21.12.2021 | Reply to a communication from the examining division | 25.01.2023 | Despatch of a communication from the examining division (Time limit: M06) | 02.08.2023 | Reply to a communication from the examining division | 12.06.2024 | Communication of intention to grant the patent | 10.10.2024 | Fee for grant paid | 10.10.2024 | Fee for publishing/printing paid | 10.10.2024 | Receipt of the translation of the claim(s) | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 01.04.2021 | Request for further processing filed | 01.04.2021 | Full payment received (date of receipt of payment) Request granted | 13.04.2021 | Decision despatched | The application is deemed to be withdrawn due to failure to indicate the wish to proceed further with the application | 01.04.2021 | Request for further processing filed | 01.04.2021 | Full payment received (date of receipt of payment) Request granted | 13.04.2021 | Decision despatched | Fees paid | Renewal fee | 27.11.2019 | Renewal fee patent year 03 | 25.02.2021 | Renewal fee patent year 04 | 18.11.2021 | Renewal fee patent year 05 | 13.10.2022 | Renewal fee patent year 06 | 27.10.2023 | Renewal fee patent year 07 | 11.10.2024 | Renewal fee patent year 08 | Penalty fee | Additional fee for renewal fee | 30.11.2020 | 04   M06   Fee paid on   25.02.2021 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [XY]US2014065621 (MHATRE RAVI [US], et al); | International search | [A]US2014066317 (TALASAZ AMIRALI [US]) [A] 1-23* See abstract; and paragraphs [0102]-[0116]. *; | [A]US2016273049 (VELCULESCU VICTOR [US], et al) [A] 1-23 * See paragraph [0090]; and claims 1-18. *; | [X] - KINDE, ISAAC et al., "Detection and quantification of rare mutations with massively parallel sequencing", Proceedings of the National Academy of Science, U.S.A., (20110607), vol. 108, no. 23, pages 9530 - 9535, XP055164202 [X] 1-23 * See pages 9530-9533, 9535; and figures 1-2. * DOI: http://dx.doi.org/10.1073/pnas.1105422108 | [A] - PENG, QUAN et al., "Reducing amplification artifacts in high multiplex amplicon sequencing by using molecular barcodes", BMC Genomics, (20150807), vol. 16, pages 1 - 12, XP021224943 [A] 1-23 * See pages 2-3, 9-11. * DOI: http://dx.doi.org/10.1186/s12864-015-1806-8 | [A] - NEWMAN, ARON M et al., "Integrated digital error suppression for improved detection of circulating tumor DNA", Nature Biotechnology, (20160500), vol. 34, no. 5, pages 547 - 555, XP055464348 [A] 1-23 * See pages 547, 549, 551; and online methods. * DOI: http://dx.doi.org/10.1038/nbt.3520 | by applicant | US5234809 | US5583024 | US5674713 | US5700673 | US6210891 | US6223128 | US6235475 | US6306597 | US2002190663 | US6828100 | US6833246 | US6911345 | US2006024681 | US2006292611 | US2007114362 | US7232656 | US2008081330 | US2009026082 | US7598035 | US2009318310 | US7666593 | US7776616 | US7809509 | US2010285578 | US7835871 | US2010304982 | US2010301398 | US2010300895 | US2010300559 | US2011009278 | US7957913 | US7960120 | US2011257889 | US2011301042 | US8165821 | US2014065621 | US2016046986 | - NEWMAN et al., "Integrated digital error suppression for improved detection of circulating tumor DNA", Nat. Bio., (20160000), vol. 34, no. 5, doi:10.1038/nbt.3520, XP055802486 DOI: http://dx.doi.org/10.1038/nbt.3520 | - XUE et al., "Optimizing the Yield and Utility of Circulating Cell-Free DNA from Plasma and Serum", Clin. Chim. Acta., (20090000), vol. 404, no. 2, doi:10.1016/j.cca.2009.02.018, pages 100 - 104, XP055536157 DOI: http://dx.doi.org/10.1016/j.cca.2009.02.018 | - LI et al., "Whole Genome Amplification of Plasma-Circulating DNA Enables Expanded Screening for Allelic Imbalance in Plasma", J. Mol Diagn., (20060200), vol. 8, no. 1, doi:10.2353/jmoldx.2006.050074, pages 22 - 30, XP055149339 DOI: http://dx.doi.org/10.2353/jmoldx.2006.050074 | - SAMBROOK, J et al., Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, (20010000), vol. 1-3, page 2,028 | - MARGULIES, M. et al., "Genome sequencing in micro-fabricated high-density picotiter reactors", Nature, (20050000), vol. I-IV, pages 376 - 380 | - ROTHBERG et al., "An integrated semiconductor device enabling non-optical genome sequencing", Nature, (20110000), vol. 475, doi:10.1038/nature10242, pages 348 - 352, XP055268437 DOI: http://dx.doi.org/10.1038/nature10242 | - KLEIN et al., "LOCAS-A low coverage sequence assembly tool for re-sequencing projects", PLoS One, (20110000), vol. 6, no. 8, page 23455 |