Deutsch English Français

Contact

EP3533451

European procedure

Quick help

Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...

News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...

Extract from the Register of European Patents

EP About this file: EP3533451

EP3533451 - APPLICATION OF PAEONIFLORIN-6'-O-BENZENE SULFONATE IN MEDICINE FOR TREATING SJÖGREN'S SYNDROME [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 02.06.2023 Database last updated on 16.11.2024
Former	The patent has been granted Status updated on 24.06.2022
Former	Grant of patent is intended Status updated on 01.11.2021
Former	Examination is in progress Status updated on 14.08.2020
Former	Request for examination was made Status updated on 02.08.2019
Former	The international publication has been made Status updated on 28.07.2018
Most recent event Tooltip	15.11.2024	Lapse of the patent in a contracting state New state(s): BG	published on 18.12.2024 [2024/51]
Applicant(s)	For all designated states Guangzhou Hanfang Pharmaceuticals Co., Ltd. 8 Conghua Wenquan Road Guangzhou Guangdong 510970 / CN
	[2021/07]
Former [2019/36]	For all designated states Ningbo Zhiming Biotechnology Co., Ltd. Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo, Zhejiang 315194 / CN
	For all designated states Wei, Wei Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo, Zhejiang 315194 / CN
Inventor(s)	01 / WEI, Wei Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	02 / WU, Huaxun Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	03 / GU, Fang Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	04 / XU, Jun Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	05 / XIE, Hongwei Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	06 / XU, Guang Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	07 / FU, Jie Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	08 / WANG, Xuezheng Room 204 Block D No. 655 Xueshi Road Yinzhou District Ningbo Zhejiang 315194 / CN
	[2019/36]
Representative(s)	Gulde & Partner Patent- und Rechtsanwaltskanzlei mbB Wallstraße 58/59 10179 Berlin / DE
	[2019/36]
Application number, filing date	17892917.0	14.02.2017
	[2019/36]
	WO2017CN73540
Priority number, date	WO2017CN71998	21.01.2017 Original published format: PCT/CN2017/071998
	[2019/36]
Filing language	ZH
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2018133139
	Date:	26.07.2018
	Language:	ZH
	[2018/30]
	Type:	A1 Application with search report
	No.:	EP3533451
	Date:	04.09.2019
	Language:	EN
	[2019/36]
	Type:	B1 Patent specification
	No.:	EP3533451
	Date:	27.07.2022
	Language:	EN
	[2022/30]
Search report(s)	International search report - published on:	CN	26.07.2018
	(Supplementary) European search report - dispatched on:	EP	18.12.2019
Classification	IPC:	A61K31/7048, A61P27/02, A61P37/00, A61K45/06	[2020/03]
	CPC:	A61K31/7048 (EP,US); A61K45/06 (EP,US); A61P27/02 (EP,US); A61P37/00 (EP,US)
	Former IPC [2019/36]	A61K31/7048, A61P27/02, A61P37/00
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/36]
Extension states	BA	Not yet paid
	ME	Not yet paid
Validation states	MA	Not yet paid
	MD	Not yet paid
Title	German:	VERWENDUNG VON PAEONIFLORIN-6'-O-BENZOLSULFONAT IN DER MEDIZIN ZUR BEHANDLUNG VON SJÖGREN-SYNDROM	[2019/36]
	English:	APPLICATION OF PAEONIFLORIN-6'-O-BENZENE SULFONATE IN MEDICINE FOR TREATING SJÖGREN'S SYNDROME	[2019/36]
	French:	APPLICATION DE PAEÉNIFLORIN-6'-O-BENZÈNE SULFONATE EN MÉDECINE POUR LE TRAITEMENT DU SYNDROME DE SJÖGREN	[2019/36]
Entry into regional phase	20.05.2019	Translation filed
	20.05.2019	National basic fee paid
	20.05.2019	Search fee paid
	20.05.2019	Designation fee(s) paid
	20.05.2019	Examination fee paid
Examination procedure	20.05.2019	Examination requested [2019/36]
	10.07.2020	Amendment by applicant (claims and/or description)
	17.08.2020	Despatch of a communication from the examining division (Time limit: M04)
	24.11.2020	Reply to a communication from the examining division
	22.01.2021	Despatch of a communication from the examining division (Time limit: M04)
	17.05.2021	Reply to a communication from the examining division
	02.11.2021	Communication of intention to grant the patent
	09.02.2022	Fee for grant paid
	09.02.2022	Fee for publishing/printing paid
	09.02.2022	Receipt of the translation of the claim(s)
Opposition(s)	02.05.2023	No opposition filed within time limit [2023/27]
Fees paid	Renewal fee
	20.05.2019	Renewal fee patent year 03
	20.02.2020	Renewal fee patent year 04
	10.02.2021	Renewal fee patent year 05
	17.06.2022	Renewal fee patent year 06
	Penalty fee
	Additional fee for renewal fee
	28.02.2022	06 M06 Fee paid on 17.06.2022
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	AL	27.07.2022
	AT	27.07.2022
	BG	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	IT	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	MC	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
	IE	14.02.2023
	LU	14.02.2023
	BE	28.02.2023
	CH	28.02.2023
	LI	28.02.2023
	[2024/51]
Former [2024/26]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	IT	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	MC	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
	IE	14.02.2023
	LU	14.02.2023
	BE	28.02.2023
	CH	28.02.2023
	LI	28.02.2023
Former [2024/12]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	MC	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
	IE	14.02.2023
	LU	14.02.2023
	BE	28.02.2023
	CH	28.02.2023
	LI	28.02.2023
Former [2024/08]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	MC	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
	IE	14.02.2023
	LU	14.02.2023
	CH	28.02.2023
	LI	28.02.2023
Former [2023/49]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	MC	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
	LU	14.02.2023
	CH	28.02.2023
	LI	28.02.2023
Former [2023/48]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	MC	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
	CH	28.02.2023
	LI	28.02.2023
Former [2023/44]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	MC	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/37]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SI	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/29]	AL	27.07.2022
	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/23]	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	EE	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SK	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/22]	AT	27.07.2022
	CZ	27.07.2022
	DK	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RO	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/21]	DK	27.07.2022
	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/20]	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	SM	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/12]	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	IS	27.11.2022
	PT	28.11.2022
Former [2023/11]	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	PL	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	PT	28.11.2022
Former [2023/10]	ES	27.07.2022
	FI	27.07.2022
	HR	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	NO	27.10.2022
	GR	28.10.2022
	PT	28.11.2022
Former [2023/09]	ES	27.07.2022
	FI	27.07.2022
	LT	27.07.2022
	LV	27.07.2022
	NL	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	NO	27.10.2022
	PT	28.11.2022
Former [2023/08]	ES	27.07.2022
	FI	27.07.2022
	LT	27.07.2022
	NL	27.07.2022
	RS	27.07.2022
	SE	27.07.2022
	NO	27.10.2022
Former [2023/06]	NL	27.07.2022
Documents cited:	Search	[Y]WO2004108216 (SHEN ZHEN LANSEN MEDICINE CO L [CN], et al) [Y] 1-10 * paragraph [0105] *;
		[Y] - LI CHUN LEI ET AL, "Effects of total glucosides of paeony for delaying onset of Sjogren's syndrome: an animal study.", JOURNAL OF CRANIO-MAXILLO-FACIAL SURGERY : OFFICIAL PUBLICATION OF THE EUROPEAN ASSOCIATION FOR CRANIO-MAXILLO-FACIAL SURGERY OCT 2013, (201310), vol. 41, no. 7, ISSN 1878-4119, pages 610 - 615, XP009517615 [Y] 1-10 * figures 1,2 * * page 610, column r, paragraph 2 * DOI: http://dx.doi.org/10.1016/j.jcms.2012.11.042
		[Y] - YU JINGYA ET AL, "Paeoniflorin down-regulates ATP-induced inflammatory cytokine production and P2X7R expression on peripheral blood mononuclear cells from patients with primary Sjogren's syndrome", INTERNATIONAL IMMUNOPHARMACOLOGY, (201509), vol. 28, no. 1, ISSN 1567-5769, pages 115 - 120, XP009517617 [Y] 1-10 * page 116, column l, paragraph 1 * * page 119, column r, paragraph l - page 120 * * figures 1-6 * DOI: http://dx.doi.org/10.1016/j.intimp.2015.05.023
		[Y] - JIA XIAOYI ET AL, "CP-25 attenuates the inflammatory response of fibroblast-like synoviocytes co-cultured with BAFF-activated CD4+T cells", JOURNAL OF ETHNOPHARMACOLOGY, ELSEVIER IRELAND LTD, IE, (20160516), vol. 189, doi:10.1016/J.JEP.2016.05.034, ISSN 0378-8741, pages 194 - 201, XP029683670 [Y] 1-10 * page 195, column l, paragraph 3 * DOI: http://dx.doi.org/10.1016/j.jep.2016.05.034
	International search	[Y]CN102603827 (WEI WEI)[Y] 1-10
		[Y] - "Baff-Baffr", (20160531), vol. 51 [Y] 1-10
	by applicant	US2015065352
		CA2949966
		CA2950423
		CA2950893
		TW201630938
		TW201630880
		TW201632559
		KR20160126734
		RU2601410
		AU2016250372
		AU2016247182
		AU2015244025
		AU2015254818
		AU2015254037
		US2016333089
		US2016333103
		US2016333409
		US2016331834
		US2016331816
		HRP20161191T
		US2016339053
		US2016339049
		US2016340337
		US2016338984
		US2016338953
		WO2016185476
		NZ702458
		MD20160069
		US2016348072
		US2016346328
		US2016346355
		US2016345547
		WO2016191545
		WO2016190630
		WO2016191634
		AU2015253915
		US9512487
		US2016356788
		US2016355591
		US2016355464
		US2016354437
		WO2016196429
		WO2016196393
		US2016362462
		US2016361407
		US2016361360
		US2016361428
		US2016361300
		WO2016200447
		HK1216994
		WO2016204429
		- Chin. J. Rheumatol., (20100000), vol. 14, no. 11, pages 766 - 768

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

Legal notice
Terms of use
24.2.25; 34p