EP3412680 - NOVEL PEPTIDES THAT BIND TO TYPES OF MHC CLASS II AND THEIR USE IN DIAGNOSIS AND TREATMENT [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 10.09.2021 Database last updated on 16.07.2024 | |
Former | The patent has been granted Status updated on 02.10.2020 | ||
Former | Grant of patent is intended Status updated on 04.06.2020 | ||
Former | Examination is in progress Status updated on 21.10.2019 | ||
Former | Request for examination was made Status updated on 28.06.2019 | ||
Former | The application has been published Status updated on 09.11.2018 | Most recent event Tooltip | 03.05.2024 | Lapse of the patent in a contracting state New state(s): MK | published on 05.06.2024 [2024/23] | Applicant(s) | For all designated states Curara AB Sälgstigen 4 181 62 Lidingö / SE | [2018/50] | Inventor(s) | 01 /
Klareskog, Lars Vanadisvägen 22B 113 46 Stockholm / SE | 02 /
Malmström, Vivianne Vintertullstorget 16 116 43 Stockholm / SE | [2018/50] | Representative(s) | Kransell & Wennborg KB P.O. Box 27834 115 93 Stockholm / SE | [2018/50] | Application number, filing date | 18151231.0 | 05.04.2012 | [2018/50] | Priority number, date | SE20110050297 | 05.04.2011 Original published format: SE 1150297 | US201161472122P | 05.04.2011 Original published format: US 201161472122 P | [2018/50] | Previously filed application, date | WO2012SE50378 | 05.04.2012 | [2018/50] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP3412680 | Date: | 12.12.2018 | Language: | EN | [2018/50] | Type: | A3 Search report | No.: | EP3412680 | Date: | 19.12.2018 | Language: | EN | [2018/51] | Type: | B1 Patent specification | No.: | EP3412680 | Date: | 04.11.2020 | Language: | EN | [2020/45] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 21.11.2018 | Classification | IPC: | C07K7/08, A61K38/10, A61P29/00, A61P37/02, C07K14/78, C07K14/47, G01N33/564 | [2018/51] | CPC: |
C07K14/78 (EP,US);
A61K38/014 (US);
A61K39/0008 (US);
A61K39/001 (US);
A61P29/00 (EP);
A61P37/02 (EP);
C07K14/47 (EP,US);
C07K14/70539 (EP,US);
C07K19/00 (EP,US);
C12N9/88 (EP,US);
C12Y402/01011 (EP,US);
G01N33/564 (EP,US);
G01N33/56977 (EP,US);
A61K2035/122 (US);
A61K38/00 (EP,US);
G01N2333/525 (US);
G01N2333/54 (US);
G01N2333/57 (US);
G01N2333/7051 (US);
G01N2333/70514 (US);
G01N2333/70539 (US);
G01N2333/70575 (US);
G01N2333/988 (US);
G01N2800/102 (EP,US);
G01N2800/24 (US)
(-)
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Former IPC [2018/50] | C07K7/08, A61K38/10, A61P29/00, A61P37/02 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/31] |
Former [2018/50] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | NEUARTIGE PEPTIDE ZUR BINDUNG AN EINZELNE TYPEN DER MHC-KLASSE-II UND DEREN VERWENDUNG IN DIAGNOSE UND BEHANDLUNG | [2018/50] | English: | NOVEL PEPTIDES THAT BIND TO TYPES OF MHC CLASS II AND THEIR USE IN DIAGNOSIS AND TREATMENT | [2018/50] | French: | NOUVEAUX PEPTIDES QUI SE LIENT À DES TYPES DE MHC DE CLASSE II ET LEUR UTILISATION DANS LE DIAGNOSTIC ET LE TRAITEMENT | [2018/50] | Examination procedure | 19.06.2019 | Amendment by applicant (claims and/or description) | 19.06.2019 | Examination requested [2019/31] | 19.06.2019 | Date on which the examining division has become responsible | 24.10.2019 | Despatch of a communication from the examining division (Time limit: M04) | 11.02.2020 | Reply to a communication from the examining division | 05.06.2020 | Communication of intention to grant the patent | 23.09.2020 | Fee for grant paid | 23.09.2020 | Fee for publishing/printing paid | 23.09.2020 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP12768393.6 / EP2694530 | Opposition(s) | 05.08.2021 | No opposition filed within time limit [2021/41] | Fees paid | Renewal fee | 11.01.2018 | Renewal fee patent year 03 | 11.01.2018 | Renewal fee patent year 04 | 11.01.2018 | Renewal fee patent year 05 | 11.01.2018 | Renewal fee patent year 06 | 15.03.2018 | Renewal fee patent year 07 | 29.04.2019 | Renewal fee patent year 08 | 11.02.2020 | Renewal fee patent year 09 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 05.04.2012 | AL | 04.11.2020 | AT | 04.11.2020 | CY | 04.11.2020 | CZ | 04.11.2020 | DK | 04.11.2020 | EE | 04.11.2020 | ES | 04.11.2020 | FI | 04.11.2020 | HR | 04.11.2020 | IT | 04.11.2020 | LT | 04.11.2020 | LV | 04.11.2020 | MC | 04.11.2020 | MK | 04.11.2020 | NL | 04.11.2020 | PL | 04.11.2020 | RO | 04.11.2020 | RS | 04.11.2020 | SI | 04.11.2020 | SK | 04.11.2020 | SM | 04.11.2020 | BG | 04.02.2021 | NO | 04.02.2021 | GR | 05.02.2021 | IS | 04.03.2021 | PT | 04.03.2021 | LU | 05.04.2021 | BE | 30.04.2021 | [2024/23] |
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Former [2021/20] | FI | 04.11.2020 | Documents cited: | Search | [X]WO2004078098 (LONDON HEALTH SCI CT RES INC [CA], et al) [X] 1,3,4,6,7,9,10 * claims 1, 18, 35; sequence 32 *; | [XI]WO2006128492 (ENTELECHON GMBH [DE], et al) [X] 1,2 * page 11; table 1 * [I] 10; | [XDI]WO2007123976 (UNIV LELAND STANFORD JUNIOR [US], et al) [XD] 1,3,4 * antigen vim58-77cit; page 14 * * paragraph [0035] * [I] 10; | [X]WO2007133702 (CELL SIGNALING TECHNOLOGY INC [US], et al) [X] 1,2 * line 303 (SEQ ID NO: 302); page 28 *; | [XI]WO2008090360 (IMP INNOVATIONS LTD [GB], et al) [X] 1,2 * page 7, lines 1-27 * * Peptide 11; page 45; table 2 * [I] 4-8,10,11; | [XI]WO2008099419 (COUNCIL SCIENT IND RES [IN], et al) [X] 1,2 * spot 59b, 59c; page 23; table 3 * [I] 10; | [XI]WO2009055820 (UNIV CALIFORNIA [US], et al) [X] 1,2 * figure 9d * [I] 10; | [A] - C CHARPIN ET AL, "HLA-DRB1*0404 is strongly associated with high titers of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis", CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, (20080101), vol. 26, no. 4, pages 627 - 631, XP055149681 [A] 1,2,4-8,10,11 * the whole document * | [A] - WEGNER N ET AL, "Evolutionarily conserved antigens in autoimmune disease: Implications for an infective aetiology", INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND CELL BIOLOGY, PERGAMON, GB, vol. 41, no. 2, doi:10.1016/J.BIOCEL.2008.09.012, ISSN 1357-2725, (20090201), pages 390 - 397, (20080924), XP026006727 [A] 1,2,4-8,10,11 * the whole document * DOI: http://dx.doi.org/10.1016/j.biocel.2008.09.012 | by applicant | WO03050542 | WO2007017556 | WO2007123976 | WO2008090360 | US2009221792 | US2009292108 | - R. B. MERRIFIELD, J. Am. Chem. Soc., (19630000), vol. 85, no. 14, pages 2149 - 2154 | - MERRIFIELD, Int. J. Peptide. Protein Res, (19900000), vol. 35, pages 161 - 214 | - ATHERTON E. et al., Bioorg Chem., (19790000), vol. 8, page 351 | - JOE SAMBROOK, Molecular Cloning: A Laboratory Manual | - NOVAK EJ; LIU AW; NEPOM GT, "Kwok WW MHC class II tetramers identify peptide-specific human CD4+ T cells proliferating in response to influenza A antigen", J Clin Invest, (19990000), vol. 104, pages R63 - 7 | - DZHAMBAZOV, B. et al., "Therapeutic Vaccination of Active Arthritis with a Glycosylated Collagen Type II Peptide in Complex with MHC Class II Molecules", J Immunol, (20060000), vol. 176, pages 1525 - 1533, XP003008498 | - SMITH, K.J.; PYRDOL, J.; GAUTHIER, L.; WILEY, D.C.; WUCHERPFENNIG, K.W., "Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein", J Exp Med, (19980000), vol. 188, doi:doi:10.1084/jem.188.8.1511, pages 1511 - 1520, XP002228793 DOI: http://dx.doi.org/10.1084/jem.188.8.1511 | - ANDERSSON, E.C. et al., "Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice", Proc Natl Acad Sci U S A, (19980000), vol. 95, pages 7574 - 7579 | - SVENDSEN, P. et al., "Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice", J Immunol, (20040000), vol. 173, pages 7037 - 7045, XP002661381 | - LARCHE; WRAITH, "Peptide-based therapeutic vaccines for allergic and autoimmune disease", Nature Medicine Supplement, (20050000), vol. 11, no. 4, doi:doi:10.1038/NM1226, pages S69 - S76, XP002509273 DOI: http://dx.doi.org/10.1038/NM1226 | - LUDVIGSSON et al., GAD N Engl J Med., (20081030), vol. 359, no. 18, pages 1909 - 20 | - TISCH et al., J Immunol., (20090000), vol. 183, pages 4809 - 4816 | - VESTBERG et al., J Immunol., (20060000), vol. 176, pages 1525 - 1533 | - SHAH et al., Journal of Internal Medicine, (20090000), vol. 266, pages 221 - 23 | - GIANFRANI et al., J Immunol., (20090000), vol. 182, pages 4158 - 4166 | - OLERUP O; ZETTERQUIST H, "HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation", Tissue Antigens, (19920000), vol. 39, pages 225 - 35, XP009090040 | - SNIR et al., Arthritis & Rheumatism, vol. 63, no. 10, pages 2873 - 2883 | - NOVAK et al., J Clin Invest, (19990000), vol. 104, pages R63 - 7 |