Extract from the Register of European Patents

EP Citations: EP3470519

Cited inSearch
Type:Patent literature
Publication No.:WO2015089419  [PA]
 (BROAD INST INC et al.)
Type:Non-patent literature
Publication information:[PX]   BERND ZETSCHE ET AL: "Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System", CELL, vol. 163, no. 3, 25 September 2015 (2015-09-25), US, pages 759 - 771, XP055267511, ISSN: 0092-8674, DOI: 10.1016/j.cell.2015.09.038
DOI: http://dx.doi.org/10.1016/j.cell.2015.09.038
Type:Non-patent literature
Publication information:[A]   GISLE VESTERGAARD ET AL: "CRISPR adaptive immune systems of Archaea", RNA BIOLOGY, vol. 11, no. 2, 14 February 2014 (2014-02-14), US, pages 156 - 167, XP055271855, ISSN: 1547-6286, DOI: 10.4161/rna.27990
DOI: http://dx.doi.org/10.4161/rna.27990
Type:Non-patent literature
Publication information:[A]   EVA SCHUNDER ET AL: "First indication for a functional CRISPR/Cas system in Francisella tularensis", INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, vol. 303, no. 2, 1 March 2013 (2013-03-01), DE, pages 51 - 60, XP055271835, ISSN: 1438-4221, DOI: 10.1016/j.ijmm.2012.11.004
DOI: http://dx.doi.org/10.1016/j.ijmm.2012.11.004
Type:Non-patent literature
Publication information:[A]   HAFT, D.H.: "HMM Summary Page: TIGR04330", 17 May 2012 (2012-05-17), XP002757584, Retrieved from the Internet
Type:Non-patent literature
Publication information:[PA]   KIRA S. MAKAROVA ET AL: "An updated evolutionary classification of CRISPR-Cas systems", NATURE REVIEWS. MICROBIOLOGY, vol. 13, no. 11, 28 September 2015 (2015-09-28), GB, pages 722 - 736, XP055271841, ISSN: 1740-1526, DOI: 10.1038/nrmicro3569
DOI: http://dx.doi.org/10.1038/nrmicro3569
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Type:Non-patent literature
Publication information:  ZETSCHE ET AL.: "Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System", CELL, vol. 163, no. 3, 2015, pages 759 - 771, XP055267511
DOI: http://dx.doi.org/10.1016/j.cell.2015.09.038
Type:Non-patent literature
Publication information:  ROHMER ET AL.: "Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains", GENOME BIOL., vol. 8, no. 6, 2007, pages R102, XP021031234
DOI: http://dx.doi.org/10.1186/gb-2007-8-6-r102
Type:Non-patent literature
Publication information:  SCHUNDER ET AL.: "First indication for a functional CRISPR/Cas system in Francisella tularensis", INT. J. MED. MICROBIOL., vol. 303, no. 2, 2013, pages 51 - 60, XP055271835
DOI: http://dx.doi.org/10.1016/j.ijmm.2012.11.004
Type:Non-patent literature
Publication information:  JINEK ET AL.: "A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity", SCIENCE, vol. 337, 2012, pages 816 - 821, XP055067740
DOI: http://dx.doi.org/10.1126/science.1225829
Type:Non-patent literature
Publication information:  MALI ET AL.: "RNA-Guided Human Genome Engineering via Cas9", SCIENCE, vol. 339, 2013, pages 823 - 826, XP055111247
DOI: http://dx.doi.org/10.1126/science.1232033
Type:Non-patent literature
Publication information:  CHO ET AL.: "Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease", NAT. BIOTECHNOL., vol. 31, 2013, pages 230 - 232, XP002699850
DOI: http://dx.doi.org/10.1038/nbt.2507
Type:Non-patent literature
Publication information:  HWANG ET AL.: "Efficient genome editing in zebrafish using a CRISPR-Cas system", NAT. BIOTECHNOL., vol. 31, 2013, pages 227 - 229, XP055086625
DOI: http://dx.doi.org/10.1038/nbt.2501
Type:Non-patent literature
Publication information:  CONG ET AL.: "Multiplex Genome Engineering Using CRISPR/Cas Systems", SCIENCE, vol. 339, 2013, pages 819 - 823, XP002779503
Type:Non-patent literature
Publication information:  VESTERGAARD ET AL.: "CRISPR adaptive immune systems of Archaea", RNA BIOL., vol. 11, 2014, pages 156 - 167, XP055271855
DOI: http://dx.doi.org/10.4161/rna.27990
Type:Non-patent literature
Publication information:  HAFT: "HMM Summary Page: TIGR04330", 17 May 2012 (2012-05-17), XP002757584
Type:Non-patent literature
Publication information:  LUNDGREN ET AL.: "CRISPR Methods and Protocols, Methods in Molecular Biology", vol. 1311, 2015, pages: 1-21, 47 - 75, XP055738628
Type:Non-patent literature
Publication information:  JIANG ET AL.: "RNA-guided editing of bacterial genomes using CRISPR-Cas systems", NAT. BIOTECHNOL., vol. 31, no. 3, 2013, pages 233 - 239, XP002741439
DOI: http://dx.doi.org/10.1038/nbt.2508
Type:Non-patent literature
Publication information:  JIANG ET AL.: "Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice", NUCLEIC ACIDS RES., vol. 41, no. 20, e188, 2013, XP055219328
DOI: http://dx.doi.org/10.1093/nar/gkt780
Type:Non-patent literature
Publication information:  ZETSCHE ET AL.: "A Survey of Genome Editing Activity for 16 Cpf1 orthologs", BIORXIV, 4 May 2017 (2017-05-04), XP055467379, Retrieved from the Internet
DOI: http://dx.doi.org/10.1101/134015
Type:Non-patent literature
Publication information:  KLEINSTIVER ET AL.: "Engineered CRISPR-Cas9 nucleases with altered PAM specificities", NATURE, vol. 523, no. 7561, 2015, pages 481 - 485, XP055293257
DOI: http://dx.doi.org/10.1038/nature14592
Type:Non-patent literature
Publication information:  GAO ET AL.: "Engineered Cpf1 variants with altered PAM specificities", NAT. BIOTECHNOL., vol. 35, no. 8, 2017, pages 789 - 792, XP055553021
DOI: http://dx.doi.org/10.1038/nbt.3900
Type:Non-patent literature
Publication information:  TENG ET AL.: "Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds", GENOME BIOL., vol. 20, 15, 2019, XP055697389
DOI: http://dx.doi.org/10.1186/s13059-019-1620-8
Type:Non-patent literature
Publication information:  ZETSCHE ET AL.: "A Survey of Genome Editing Activity for 16 Cas12a Orthologs", KEIO J. MED., vol. 69, no. 3, 2019, pages 59 - 65, XP055738652
DOI: http://dx.doi.org/10.2302/kjm.2019-0009-OA
Type:Non-patent literature
Publication information:  GRAHAM ET AL.: "Resources for the design of CRISPR gene editing experiments", GENOME BIOL., vol. 16, 260, 2015, XP055377553
DOI: http://dx.doi.org/10.1186/s13059-015-0823-x
Type:Non-patent literature
Publication information:  VAN DER OOST ET AL.: "Unravelling the structural and mechanistic basis of CRISPR-Cas systems", NAT REV MICROBIOL, vol. 12, 2014, pages 479 - 492, XP055619310
DOI: http://dx.doi.org/10.1038/nrmicro3279
Type:Non-patent literature
Publication information:  HOCHSTRASSER ET AL.: "CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference", PNAS, vol. 111, no. 18, 2014, pages 6618 - 6623, XP055752880
DOI: http://dx.doi.org/10.1073/pnas.1405079111
Type:Non-patent literature
Publication information:  SCHUNDER ET AL.: "First indication for a functional CRISPR/Cas system in Francisella tularensis", INT J MED MICRO, vol. 303, 2013, pages 51 - 60, XP055271835
DOI: http://dx.doi.org/10.1016/j.ijmm.2012.11.004
Type:Non-patent literature
Publication information:  LUNDGREN ET AL.: "CRISPR. METHODS AND PROTOCOLS, METHODS IN MOLECULAR BIOLOGY", vol. 1311, 2015, New York, NY, article HEIDRICH ET AL.: "Investigating CRISPR RNA Biogenesis and Function Using RNA-seq", pages: 1 - 21, XP055738628
Type:Non-patent literature
Publication information:  HOU ET AL.: "Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis", PNAS, vol. 110, no. 39, 2013, pages 15644 - 15649, XP055118866
DOI: http://dx.doi.org/10.1073/pnas.1313587110
Type:Non-patent literature
Publication information:  ZHANG ET AL.: "DNase H Activity of Neisseria meningitidis Cas9", MOLECULAR CELL, vol. 60, 2015, pages 242 - 255, XP055451491
DOI: http://dx.doi.org/10.1016/j.molcel.2015.09.020
Type:Non-patent literature
Publication information:  CHEMELLO ET AL.: "Microgenomic Analysis in Skeletal Muscle: Expression Signatures of Individual Fast and Slow Myofibers", PLOS ONE, vol. 6, no. 2, e16807, 2011, XP055753232
DOI: http://dx.doi.org/10.1371/journal.pone.0016807
Type:Non-patent literature
Publication information:  BERND ZETSCHE; JONATHAN S GOOTENBERG; OMAR O ABUDAYYEH; IAN M SLAYMAKER; KIRA S MAKAROVA; PATRICK ESSLETZBICHLER; SARA E VOLZ; JUL: "Cpf1 is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System", CELL, vol. 163, 22 October 2015 (2015-10-22), pages 759 - 771, XP055267511, DOI: 10.1016/j.cell.2015.09.038
DOI: http://dx.doi.org/10.1016/j.cell.2015.09.038
Type:Non-patent literature
Publication information:  JINEK M; ET AL: "A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity", SCIENCE, vol. 337, 201200817, pages 816 - 821, XP055549487, DOI: 10.1126/science.1225829
DOI: http://dx.doi.org/10.1126/science.1225829
Type:Non-patent literature
Publication information:  JOHN VAN DER OOST; EDZE R WESTRA; RYAN N JACKSON; BLAKE WIEDENHEFT: "Unravelling the structural and mechanistic basis of CRISPR-Cas systems", NAT REV MICROBIOL, vol. 12, no. 7, July 2014 (2014-07-01), pages 479 - 492, XP055619310, DOI: 10.1038/nrmicro3279
DOI: http://dx.doi.org/10.1038/nrmicro3279
Type:Non-patent literature
Publication information:  FEI ANN RAN: "CRISPR-Cas: Development and Applications for Mammalian Genome Editing", PHD THESIS, 24 April 2014 (2014-04-24), pages 1 - 156, XP055754930
Type:Non-patent literature
Publication information:  MAGNUS LUNDGREN; ET AL: "CRISPR Methods and Protocols, Methods in Molecular Biology,", vol. 1311, May 2015, HUMANA PRESS, article NADJA HEIDRICH; GAURAV DUGAR; JORG VOGEL; CYNTHIA M SHARMA; KIRA S MAKAROVA AND EUGENE V KOONIN: "Chapters 1 and 4", pages: 1 - 21, 47-75, XP055738628
Type:Non-patent literature
Publication information:  EVA SCHUNDER; KERSTIN RYDZEWSKI; ROLAND GRUNOW; KLAUS HEUNER: "First indication for a functional CRISPR/Cas system in Francisella tularensis", INT. J OF MEDICAL MICROBIOLOGY, vol. 303, 2013, pages 51 - 60, XP055271835, DOI: 10.1016/j.ijmm.2012.11.004
DOI: http://dx.doi.org/10.1016/j.ijmm.2012.11.004
Type:Non-patent literature
Publication information:  GISLE VESTERGAARD; ROGER A GARRETT; SHIRAZ A SHAH: "CRISPR adaptive immune systems of Archaea", RNA BIOLOGY, vol. 11, no. 2, February 2014 (2014-02-01), pages 156 - 167, XP055271855, DOI: 10.4161/rna.27990
DOI: http://dx.doi.org/10.4161/rna.27990
Type:Non-patent literature
Publication information:  HAFT D H: "HMM Summary Page: TIGR04330", 17 May 2012 (2012-05-17), pages 1, XP002757584, Retrieved from the Internet
Type:Non-patent literature
Publication information:  DATABASE Nucleotide NCBI; 7 February 2014 (2014-02-07), "Francisella tularensis subsp. novicida U112, complete genome", XP055741415, Database accession no. CP000439
Type:Non-patent literature
Publication information:  JIANG W; ZHOU H; BI H; FROMM M; YANG B; WEEKS D P: "Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice", NUCLEIC ACIDS RESEARCH, vol. 41, no. 20, 2013, pages 1 - 12, XP055219328, DOI: 10.1093/nar/gkt780
DOI: http://dx.doi.org/10.1093/nar/gkt780
Type:Non-patent literature
Publication information:  PRAKASH T P; GRAHAM M J; YU J; CARTY R; LOW A; CHAPPELL A; SCHMIDT K; ZHAO C; AGHAJAN M; MURRAY H F; RINEY S; BOOTEN S L; MURRAY S: "Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10- fold in mice", NUCLEIC ACIDS RESEARCH, vol. 42, no. 13, 2014, pages 8796 - 8807, XP055148318, DOI: 10.1093/nar/gku531
DOI: http://dx.doi.org/10.1093/nar/gku531
Type:Non-patent literature
Publication information:  RODOLPHE BARRANGOU; LUCIANO A MARRAFFINI: "CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity", MOLECULAR CELL, vol. 54, April 2014 (2014-04-01), pages 234 - 244, XP055190330, DOI: 10.1016/j.molcel.2014.03.011
DOI: http://dx.doi.org/10.1016/j.molcel.2014.03.011
Type:Non-patent literature
Publication information:  FAGERLUND R D; STAALS R H; FINERAN P C: "The Cpf1 CRISPR-Cas protein expands genome-editing tools", GENOME BIOLOGY, vol. 16, 17 November 2015 (2015-11-17), pages 251-1 - 251-3, XP002757560, DOI: 10.1186/s13059-015-0824-9
DOI: http://dx.doi.org/10.1186/s13059-015-0824-9
Type:Non-patent literature
Publication information:  GRISSA I; VERGNAUD G; POURCEL C: "CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats", NUCLEIC ACIDS RESEARCH, vol. 35, 2007, pages W52 - W57, XP002490217, DOI: 10.1093/nar/gkm360
DOI: http://dx.doi.org/10.1093/nar/gkm360
Type:Non-patent literature
Publication information:  MICHA BURMISTRZ; DUDEK BARTOSZ; STANIEC DOMINIKA; RODRIGUEZ MARTINEZ JOSE IGNACIO; BOCHTLER MATTHIAS; POTEMPA JAN; PYRC KRZYSZTOF: "Functional analysis of Porphyromonas gingivalis W83 CRISPR-Cas systems", JB ACCEPTED MANUSCRIPT / J. BACTERIOL., 26 May 2015 (2015-05-26), pages 1 - 33, XP055756419
Type:Non-patent literature
Publication information:  MOJICA F J M; DIEZ-VILLASENOR C; GARCIA-MARTINEZ J; ALMENDROS C: "Short motif sequences determine the targets of the prokaryotic CRISPR defence system", MICROBIOLOGY, vol. 155, no. 3, 2009, pages 733 - 740, XP055118366, DOI: 10.1099/mic.0.023960-0
DOI: http://dx.doi.org/10.1099/mic.0.023960-0
Type:Non-patent literature
Publication information:  ZETSCHE B. , JONATHAN S. GOOTENBERG, OMAR O. ABUDAYYEH AVIV REGEV, EUGENE V. KOONIN, FENG ZHANG: "Cpf is a single RNA- guided endonuclease of a class 2 CRISPR- Cas system", CELL, vol. 163, no. 3, 25 September 2015 (2015-09-25), pages 759 - 771, XP055838963
Type:Non-patent literature
Publication information:  ROHMER LAURENCE; FONG CHRISTINE; ABMAYR SIMONE; WASNICK MICHAEL; LARSON FREEMAN THEODORE J; RADEY MATTHEW; GUINA TINA; SVENSSON KE: "Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains", GENOME BIOLOGY, vol. 8, no. 6, R102, 5 June 2007 (2007-06-05), XP021031234
DOI: http://dx.doi.org/10.1186/gb-2007-8-6-r102
Type:Non-patent literature
Publication information:  EVA SCHUNDER; KERSTIN RYDZEWSKI; ROLAND GRUNOW; KLAUS HEUNER: "First indication for a functional CRISPR/Cas system in Francisella tularensis", INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, vol. 303, no. 2, 1 March 2013 (2013-03-01), pages 51 - 60, XP055271835
DOI: http://dx.doi.org/10.1016/j.ijmm.2012.11.004
Type:Non-patent literature
Publication information:  JINEK M; CHYLINSKI K; FONFARA I; HAUER M; DOUDNA J A; CHARPENTIER E: "A Programmable Dual-RNA-GuidedDNA Endonuclease in Adaptive Bacterial Immunity", SCIENCE, vol. 337, 17 August 2012 (2012-08-17), XP055549487
DOI: http://dx.doi.org/10.1126/science.1225829
Type:Non-patent literature
Publication information:  GISLE VESTERGAARD; ROGER A GARRETT; SHIRAZ A SHAH: "CRISPR adaptive immune systems of Archaea", RNA BIOLOGY, vol. 11, no. 2, 14 February 2014 (2014-02-14), pages 156 - 167, XP055271855
DOI: http://dx.doi.org/10.4161/rna.27990
Type:Non-patent literature
Publication information:  LUNDGREN; ET AL: "CRISPR: Methods and Protocols", METHODS IN MOLECULAR BIOLOGY, vol. 1311, 2015, XP055476456
Type:Non-patent literature
Publication information:  JOHN VAN DER OOST; EDZE R WESTRA; RYAN N JACKSON; BLAKE WIEDENHEFT: "Unravelling the structural and mechanistic basis of CRISPR-Cas systems", NATURE REVIEWS MICROBIOLOGY, vol. 12, no. 7, 1 July 2014 (2014-07-01), pages 479 - 492, XP055619310
DOI: http://dx.doi.org/10.1038/nrmicro3279
Type:Non-patent literature
Publication information:  FEI ANN RAN: "CRISPR-Cas: Development and Applications for Mammalian Genome Editing", THESIS, 24 April 2014 (2014-04-24), pages 1 - 156, XP055754930
Type:Non-patent literature
Publication information:  DATABASE NUCLEOTIDE 7 February 2014 (2014-02-07), ANONYMOUS: "Francisella tularensis subsp. novicida U112, complete genome", XP055741415, retrieved from NCBI Database accession no. CP000439
Type:Non-patent literature
Publication information:  JIANG W; ZHOU H; BI H; FROMM M; YANG B; WEEKS D P: "Demonstration of CRISPR/Cas9/sgRNA-mediatedtargeted gene modification in Arabidopsis, tobacco, sorghum and rice", NUCLEIC ACIDS RESEARCH, vol. 41, no. 20, 2 September 2013 (2013-09-02), pages e188, XP055219328
DOI: http://dx.doi.org/10.1093/nar/gkt780
Type:Non-patent literature
Publication information:  PRAKASH T P; GRAHAM M J; YU J; CARTY R; LOW A; CHAPPELL A; SCHMIDT K; ZHAO C; AGHAJAN M; MURRAY H F; RINEY S; BOOTEN S L; MURRAY S: "Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice", NUCLEIC ACIDS RESEARCH, vol. 42, no. 13, 1 September 2014 (2014-09-01), pages 8796 - 8807, XP055148318
DOI: http://dx.doi.org/10.1093/nar/gku531
Type:Non-patent literature
Publication information:  RODOLPHE BARRANGOU; LUCIANO A MARRAFFINI: "CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity", MOLECULAR CELL, vol. 54, no. 2, 1 April 2014 (2014-04-01), pages 234 - 244, XP055190330
DOI: http://dx.doi.org/10.1016/j.molcel.2014.03.011
Type:Non-patent literature
Publication information:  FAGERLUND R D; RAYMOND H J STAALS AND PETER C FINERAN: "The Cpf1 CRISPR- Cas protein expands genome editing tools", GENOME BIOLOGY, vol. 16, no. 251, 17 November 2015 (2015-11-17), pages 1 - 3, XP055838967
Type:Non-patent literature
Publication information:  GRISSA I; VERGNAUD G; POURCEL C: "CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats", NUCLEIC ACIDS RESEARCH, vol. 35, 2070531, pages W52 - W57, XP002490217
DOI: http://dx.doi.org/10.1093/nar/gkm360
Type:Non-patent literature
Publication information:  MICHA BURMISTRZ; DUDEK BARTOSZ; STANIEC DOMINIKA; RODRIGUEZ MARTINEZ JOSE IGNACIO; BOCHTLER MATTHIAS; POTEMPA JAN; PYRC KRZYSZTOF: "Functional analysis of Porphyromonas gingivalis W83 CRISPR-Cas systems", JOURNAL OF BACTERIOLOGY, vol. 197, no. 16, 15 August 2015 (2015-08-15), pages 2631 - 2641, XP055755640
DOI: http://dx.doi.org/10.1128/JB.00261-15
Type:Non-patent literature
Publication information:  MOJICA F J M; DIEZ-VILLASENOR C; GARCIA-MARTINEZ J; ALMENDROS C: "Short motif sequences determine the targets of the prokaryotic CRISPR defence system", MICROBIOLOGY, no. 3, 1 March 2009 (2009-03-01), pages 733 - 740, XP055118633
DOI: http://dx.doi.org/10.1099/mic.0.023960-0
Type:Non-patent literature
Publication information:  ZHANG ET AL.: "Expanding the catalog of cas genes with metagenomes", NUCLEIC ACIDS RESEARCH, vol. 42, no. 4, 6 December 2013 (2013-12-06), pages 2448 - 2459, XP055181273, DOI: 10.1093/nar/gkt1262
DOI: http://dx.doi.org/10.1093/nar/gkt1262
Type:Non-patent literature
Publication information:  HAFT ET AL.: "TIGRFAMs and Genome Properties in 2013", NUCLEIC ACIDS RESEARCH, vol. 41, 28 November 2012 (2012-11-28), pages D387 - D395