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Extract from the Register of European Patents

EP About this file: EP3415620

EP3415620 - ADENO-ASSOCIATED VIRUS VECTORS FOR TREATMENT OF GLYCOGEN STORAGE DISEASE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  04.02.2022
Database last updated on 17.07.2024
FormerThe patent has been granted
Status updated on  26.02.2021
FormerGrant of patent is intended
Status updated on  21.10.2020
FormerExamination is in progress
Status updated on  20.04.2020
FormerRequest for examination was made
Status updated on  28.06.2019
FormerThe application has been published
Status updated on  16.11.2018
Most recent event   Tooltip03.05.2024Lapse of the patent in a contracting state
New state(s): MK		published on 05.06.2024  [2024/23]
Applicant(s)For all designated states
The United States of America, as represented by The Secretary, Department of Health and Human Services
National Institutes of Health
Office of Technology Transfer
6011 Executive Boulevard
Suite 325, MSC 7660
Bethesda, MD 20852-7660 / US
[2019/13]
Former [2018/51]For all designated states
The United States of America, as represented by The Secretary, Department of Health and Human Services
National Institutes of Health
Office of Technology Transfer
6011 Executive Boulevard
Suite 325, MSC 7660
Bethesda, MD 20852-7660 / US
For all designated states
University of Florida Research Foundation, Inc.
223 Grinter Hall
Gainesville, FL 32611 / US
Inventor(s)01 / CHOU, Janice, J.
NIH/NICHD
Building 10
Room 9D42
Bethesda, MD 20892 / US
 [2019/04]
Former [2018/51]01 / CHOU, Janice, J.
NIH/NICHD
Building 10
Room 9D42
Bethesda, MD 20892 / US
02 / BYRNE, Barry, J.
University of Florida
Child Health Research Institute
PO Box 100296
Gainsville, FL 32610-0296 / US
Representative(s)Forresters IP LLP
Skygarden
Erika-Mann-Straße 11
80636 München / DE
[2021/13]
Former [2018/51]Gowshall, Jonathan Vallance
Forresters IP LLP
Skygarden
Erika-Mann-Strasse 11
80636 München / DE
Application number, filing date18186594.025.11.2014
[2018/51]
Priority number, dateUS201361908861P26.11.2013         Original published format: US 201361908861 P
[2018/51]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3415620
Date:19.12.2018
Language:EN
[2018/51]
Type: B1 Patent specification 
No.:EP3415620
Date:31.03.2021
Language:EN
[2021/13]
Search report(s)(Supplementary) European search report - dispatched on:EP17.10.2018
ClassificationIPC:C12N9/16, A61K48/00, C12N15/86, A61P1/16, A61P3/06, A61P3/08, A61P3/10, A61P13/12, A61P19/06
[2020/46]
CPC:
C12N15/86 (EP,US); A61K48/0008 (US); A61K48/005 (EP,US);
A61K48/0066 (EP,US); A61K48/0075 (EP,US); A61P1/16 (EP);
A61P13/12 (EP); A61P19/06 (EP); A61P3/06 (EP);
A61P3/08 (EP); A61P3/10 (EP); C12N7/00 (US);
C12N9/16 (EP,US); C12Y301/03009 (EP,US); C12N2750/14143 (EP,US);
C12N2830/008 (EP,US); C12N2830/42 (EP,US) (-)
Former IPC [2018/51]C12N9/16, A61K48/00, C12N15/86
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/31]
Former [2018/51]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:ADENOASSOZIIERTE VIRUSVEKTOREN ZUR BEHANDLUNG DER GLYKOGENSPEICHERKRANKHEIT[2018/51]
English:ADENO-ASSOCIATED VIRUS VECTORS FOR TREATMENT OF GLYCOGEN STORAGE DISEASE[2018/51]
French:VECTEURS DE TYPE VIRUS ADÉNO-ASSOCIÉ POUR LE TRAITEMENT DE MALADIE DU STOCKAGE DU GLYCOGÈNE[2018/51]
Examination procedure19.06.2019Amendment by applicant (claims and/or description)
19.06.2019Examination requested  [2019/31]
19.06.2019Date on which the examining division has become responsible
23.04.2020Despatch of a communication from the examining division (Time limit: M02)
11.06.2020Reply to a communication from the examining division
22.10.2020Communication of intention to grant the patent
17.02.2021Fee for grant paid
17.02.2021Fee for publishing/printing paid
17.02.2021Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP14812375.5  / EP3074510
Opposition(s)04.01.2022No opposition filed within time limit [2022/10]
Fees paidRenewal fee
31.07.2018Renewal fee patent year 03
31.07.2018Renewal fee patent year 04
27.11.2018Renewal fee patent year 05
27.11.2019Renewal fee patent year 06
27.11.2020Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.11.2014
AL31.03.2021
AT31.03.2021
CY31.03.2021
CZ31.03.2021
DK31.03.2021
EE31.03.2021
ES31.03.2021
FI31.03.2021
GR31.03.2021
HR31.03.2021
IT31.03.2021
LT31.03.2021
LV31.03.2021
MC31.03.2021
MK31.03.2021
NL31.03.2021
PL31.03.2021
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BG30.06.2021
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IS31.07.2021
PT02.08.2021
IE25.11.2021
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BE30.11.2021
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LI30.11.2021
[2024/23]
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PT02.08.2021
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NO30.06.2021
IS31.07.2021
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LT31.03.2021
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MC31.03.2021
NL31.03.2021
PL31.03.2021
RO31.03.2021
RS31.03.2021
SE31.03.2021
SI31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
NO30.06.2021
IS31.07.2021
PT02.08.2021
LU25.11.2021
BE30.11.2021
CH30.11.2021
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SE31.03.2021
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SM31.03.2021
BG30.06.2021
NO30.06.2021
IS31.07.2021
PT02.08.2021
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CZ31.03.2021
DK31.03.2021
EE31.03.2021
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MC31.03.2021
NL31.03.2021
PL31.03.2021
RO31.03.2021
RS31.03.2021
SE31.03.2021
SI31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
NO30.06.2021
IS31.07.2021
PT02.08.2021
LU25.11.2021
BE30.11.2021
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EE31.03.2021
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HR31.03.2021
LT31.03.2021
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MC31.03.2021
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PL31.03.2021
RO31.03.2021
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SE31.03.2021
SI31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
NO30.06.2021
IS31.07.2021
PT02.08.2021
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PL31.03.2021
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SI31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
NO30.06.2021
IS31.07.2021
PT02.08.2021
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DK31.03.2021
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ES31.03.2021
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SK31.03.2021
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NO30.06.2021
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EE31.03.2021
ES31.03.2021
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PL31.03.2021
RO31.03.2021
RS31.03.2021
SE31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
NO30.06.2021
PT02.08.2021
IS29.12.2021
Former [2022/08]AL31.03.2021
AT31.03.2021
CZ31.03.2021
DK31.03.2021
EE31.03.2021
ES31.03.2021
FI31.03.2021
HR31.03.2021
LT31.03.2021
LV31.03.2021
NL31.03.2021
PL31.03.2021
RO31.03.2021
RS31.03.2021
SE31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
NO30.06.2021
IS31.07.2021
PT02.08.2021
Former [2022/07]AL31.03.2021
AT31.03.2021
CZ31.03.2021
EE31.03.2021
FI31.03.2021
HR31.03.2021
LT31.03.2021
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NL31.03.2021
PL31.03.2021
RO31.03.2021
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SE31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
NO30.06.2021
IS31.07.2021
PT02.08.2021
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EE31.03.2021
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PL31.03.2021
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SE31.03.2021
SK31.03.2021
SM31.03.2021
BG30.06.2021
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IS31.07.2021
PT02.08.2021
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EE31.03.2021
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Documents cited:Search[Y]EP2412387  (PROYECTO BIOMEDICINA CIMA SL [ES]) [Y] 1-15 * paragraph [0182] *;
 [YD]  - WAI HAN YIU ET AL, "Complete Normalization of Hepatic G6PC Deficiency in Murine Glycogen Storage Disease Type Ia Using Gene Therapy", MOLECULAR THERAPY, (20100413), vol. 18, no. 6, doi:10.1038/mt.2010.64, ISSN 1525-0016, pages 1076 - 1084, XP055174494 [YD] 1-15 * page 1083 *

DOI:   http://dx.doi.org/10.1038/mt.2010.64
 [YD]  - LEE YOUNG MOK ET AL, "The upstream enhancer elements of theG6PCpromoter are critical for optimal G6PC expression in murine glycogen storage disease type Ia", MOLECULAR GENETICS AND METABOLISM, (20130625), vol. 110, no. 3, doi:10.1016/J.YMGME.2013.06.014, ISSN 1096-7192, pages 275 - 280, XP028754654 [YD] 1-15 * page 275 - page 279 *

DOI:   http://dx.doi.org/10.1016/j.ymgme.2013.06.014
 [Y]  - ZHIJIAN WU ET AL, "Optimization of Self-complementary AAV Vectors for Liver-directed Expression Results in Sustained Correction of Hemophilia B at Low Vector Dose", MOLECULAR THERAPY, (200802), vol. 16, no. 2, doi:10.1038/sj.mt.6300355, ISSN 1525-0016, pages 280 - 289, XP055097643 [Y] 1-15 * page 283 *

DOI:   http://dx.doi.org/10.1038/sj.mt.6300355
 [Y]  - GRIEGER J C ET AL, "PACKAGING CAPACITY OF ADENO-ASSOCIATED VIRUS SEROTYPES: IMPACT OF LARGER GENOMES ON INFECTIVITY AND POSTENTRY STEPS", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (200508), vol. 79, no. 15, doi:10.1128/JVI.79.15.9933-9944.2005, ISSN 0022-538X, pages 9933 - 9944, XP009054356 [Y] 1-15 * figures 1, 5 *

DOI:   http://dx.doi.org/10.1128/JVI.79.15.9933-9944.2005
 [A]  - JANICE Y. CHOU ET AL, "Mutations in the glucose-6-phosphatase-[alpha] (G6PC) gene that cause type Ia glycogen storage disease", HUMAN MUTATION, US, (200807), vol. 29, no. 7, doi:10.1002/humu.20772, ISSN 1059-7794, pages 921 - 930, XP055512547 [A] 4,6 * figures 3,4 *

DOI:   http://dx.doi.org/10.1002/humu.20772
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