Extract from the Register of European Patents

EP About this file: EP3469907

EP3469907 - SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  07.01.2022
Database last updated on 08.04.2026
FormerThe patent has been granted
Status updated on  29.01.2021
FormerGrant of patent is intended
Status updated on  28.09.2020
FormerExamination is in progress
Status updated on  28.02.2020
FormerRequest for examination was made
Status updated on  25.10.2019
FormerThe application has been published
Status updated on  15.03.2019
Most recent event   Tooltip19.12.2025Lapse of the patent in a contracting state
New state(s): TR
published on 21.01.2026  [2026/04]
Applicant(s)For all designated states
Aclaris Therapeutics, Inc.
640 Lee Road
Suite 200
Wayne, Pennsylvania 19087 / US
[2019/16]
Inventor(s)01 / SELNESS, Shaun R.
1875 Cedarmill Drive
Chesterfield, MO 63017 / US
02 / MONAHAN, Joseph B.
6 Lombardy Way
St Louis, MO 63138 / US
03 / SCHINDLER, John F.
15801 Timber Valley Rd. Apt. M
Chesterfield, MO 63017 / US
04 / DEVADAS, Belekudru
2175 Parasol Drive
Chesterfield, MO 63017 / US
 [2019/16]
Representative(s)Haseltine Lake Kempner LLP
One Portwall Square
Portwall Lane
Bristol BS1 6BH / GB
[N/P]
Former [2021/09]Haseltine Lake Kempner LLP
Redcliff Quay
120 Redcliff Street
Bristol BS1 6HU / GB
Former [2019/16]Haseltine Lake LLP
Redcliff Quay 120 Redcliff Street
Bristol BS1 6HU / GB
Application number, filing date18192593.406.12.2011
[2019/16]
Priority number, dateUS201042007410P06.12.2010         Original published format: US 42007410 P
[2019/16]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3469907
Date:17.04.2019
Language:EN
[2019/16]
Type: B1 Patent specification 
No.:EP3469907
Date:03.03.2021
Language:EN
[2021/09]
Search report(s)(Supplementary) European search report - dispatched on:EP04.02.2019
ClassificationIPC:A61K31/44, A61P35/00, A61P3/10, A61P29/00, A61P37/00, C07D417/14, C07D409/14, A61K31/506, A61K31/4412, C07D413/14
[2020/42]
CPC:
C07D401/14 (EP,US); A61K31/444 (EP,US); A61K31/506 (EP,US);
A61K45/06 (EP,US); A61P17/00 (EP); A61P29/00 (EP);
A61P3/00 (EP); A61P3/10 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P37/00 (EP); A61P37/02 (EP);
A61P9/10 (EP); C07D401/04 (EP,US); C07D409/14 (EP,US);
C07D413/14 (EP,US); C07D417/14 (EP,US) (-)
Former IPC [2019/16]A01N43/40, A61K31/44, C07D413/14, A61K31/4412, A61K31/506, C07D409/14, C07D417/14, A61P37/00, A61P29/00, A61P3/10, A61P35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/48]
Former [2019/16]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:SUBSTITUIERTE PYRIDINON-PYRIDINYL-VERBINDUNGEN[2019/16]
English:SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS[2019/16]
French:COMPOSÉS PYRIDINONE-PYRIDINYL SUBSTITUÉS[2019/16]
Examination procedure17.10.2019Amendment by applicant (claims and/or description)
17.10.2019Examination requested  [2019/48]
17.10.2019Date on which the examining division has become responsible
03.03.2020Despatch of a communication from the examining division (Time limit: M04)
06.07.2020Reply to a communication from the examining division
28.09.2020Communication of intention to grant the patent
21.01.2021Fee for grant paid
21.01.2021Fee for publishing/printing paid
21.01.2021Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP11847595.3  / EP2648516
Opposition(s)06.12.2021No opposition filed within time limit [2022/06]
Fees paidRenewal fee
04.01.2019Renewal fee patent year 03
04.01.2019Renewal fee patent year 04
04.01.2019Renewal fee patent year 05
04.01.2019Renewal fee patent year 06
04.01.2019Renewal fee patent year 07
31.12.2018Renewal fee patent year 08
27.12.2019Renewal fee patent year 09
28.12.2020Renewal fee patent year 10
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Lapses during opposition  TooltipHU06.12.2011
AL03.03.2021
AT03.03.2021
CY03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
MK03.03.2021
MT03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
TR03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
[2026/04]
Former [2024/42]HU06.12.2011
AL03.03.2021
AT03.03.2021
CY03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
MK03.03.2021
MT03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2024/23]HU06.12.2011
AL03.03.2021
AT03.03.2021
CY03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
MK03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2023/33]HU06.12.2011
AL03.03.2021
AT03.03.2021
CY03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2023/24]AL03.03.2021
AT03.03.2021
CY03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2022/33]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
MC03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2022/23]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2022/13]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SI03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
Former [2022/10]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
Former [2022/08]AL03.03.2021
AT03.03.2021
CZ03.03.2021
DK03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2022/07]AL03.03.2021
AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2021/51]AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
IS03.07.2021
PT05.07.2021
Former [2021/50]AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RO03.03.2021
RS03.03.2021
SE03.03.2021
SK03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
PT05.07.2021
Former [2021/48]AT03.03.2021
CZ03.03.2021
EE03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/46]AT03.03.2021
FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
SM03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/43]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
NL03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/39]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
PL03.03.2021
RS03.03.2021
SE03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/38]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
RS03.03.2021
SE03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/37]FI03.03.2021
HR03.03.2021
LT03.03.2021
LV03.03.2021
RS03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/36]FI03.03.2021
HR03.03.2021
LT03.03.2021
BG03.06.2021
NO03.06.2021
GR04.06.2021
Former [2021/35]FI03.03.2021
HR03.03.2021
LT03.03.2021
NO03.06.2021
Former [2021/33]FI03.03.2021
LT03.03.2021
NO03.06.2021
Documents cited:Search[A] WO03068230  (PHARMACIA CORP et al.)
 [A] WO2005018557  (PHARMACIA CORP et al.)
 [A] EP1741702  (ONO PHARMACEUTICAL CO et al.)
 [A] EP1447401  (ONO PHARMACEUTICAL CO et al.)
 [A]   ESSA HU ET AL: "Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit +", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 11, 1 June 2008 (2008-06-01), pages 3065 - 3068, XP055108943, ISSN: 0022-2623, DOI: 10.1021/jm800188g

DOI:   http://dx.doi.org/10.1021/jm800188g
by applicantWO0017175
 WO0071535
 WO0242292
 WO2008062905
 WO2005018557
 US2007167621
 WO2004087677
 WO2007081901
 WO2008153942
 US7067540
 US2005176775
 US7345054
 US2007003993
   DAVIDSON ET AL.: "Discovery and characterization of a substrate selective p38alpha inhibitor", BIOCHEMISTRY, vol. 43, 2004, pages 11658 - 11671
   BURNETTE ET AL.: "SD0006: a potent, selective and orally available inhibitor of p38 kinase", PHARMACOLOGY, vol. 84, no. 1, 2009, pages 42 - 60
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.