| EP3469907 - SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 07.01.2022 Database last updated on 08.04.2026 | |
| Former | The patent has been granted Status updated on 29.01.2021 | ||
| Former | Grant of patent is intended Status updated on 28.09.2020 | ||
| Former | Examination is in progress Status updated on 28.02.2020 | ||
| Former | Request for examination was made Status updated on 25.10.2019 | ||
| Former | The application has been published Status updated on 15.03.2019 | Most recent event Tooltip | 19.12.2025 | Lapse of the patent in a contracting state New state(s): TR | published on 21.01.2026 [2026/04] | Applicant(s) | For all designated states Aclaris Therapeutics, Inc. 640 Lee Road Suite 200 Wayne, Pennsylvania 19087 / US | [2019/16] | Inventor(s) | 01 /
SELNESS, Shaun R. 1875 Cedarmill Drive Chesterfield, MO 63017 / US | 02 /
MONAHAN, Joseph B. 6 Lombardy Way St Louis, MO 63138 / US | 03 /
SCHINDLER, John F. 15801 Timber Valley Rd. Apt. M Chesterfield, MO 63017 / US | 04 /
DEVADAS, Belekudru 2175 Parasol Drive Chesterfield, MO 63017 / US | [2019/16] | Representative(s) | Haseltine Lake Kempner LLP One Portwall Square Portwall Lane Bristol BS1 6BH / GB | [N/P] |
| Former [2021/09] | Haseltine Lake Kempner LLP Redcliff Quay 120 Redcliff Street Bristol BS1 6HU / GB | ||
| Former [2019/16] | Haseltine Lake LLP Redcliff Quay 120 Redcliff Street Bristol BS1 6HU / GB | Application number, filing date | 18192593.4 | 06.12.2011 | [2019/16] | Priority number, date | US201042007410P | 06.12.2010 Original published format: US 42007410 P | [2019/16] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3469907 | Date: | 17.04.2019 | Language: | EN | [2019/16] | Type: | B1 Patent specification | No.: | EP3469907 | Date: | 03.03.2021 | Language: | EN | [2021/09] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 04.02.2019 | Classification | IPC: | A61K31/44, A61P35/00, A61P3/10, A61P29/00, A61P37/00, C07D417/14, C07D409/14, A61K31/506, A61K31/4412, C07D413/14 | [2020/42] | CPC: |
C07D401/14 (EP,US);
A61K31/444 (EP,US);
A61K31/506 (EP,US);
A61K45/06 (EP,US);
A61P17/00 (EP);
A61P29/00 (EP);
A61P3/00 (EP);
A61P3/10 (EP);
A61P35/00 (EP);
A61P35/02 (EP);
A61P37/00 (EP);
A61P37/02 (EP);
A61P9/10 (EP);
C07D401/04 (EP,US);
C07D409/14 (EP,US);
|
| Former IPC [2019/16] | A01N43/40, A61K31/44, C07D413/14, A61K31/4412, A61K31/506, C07D409/14, C07D417/14, A61P37/00, A61P29/00, A61P3/10, A61P35/00 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/48] |
| Former [2019/16] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | SUBSTITUIERTE PYRIDINON-PYRIDINYL-VERBINDUNGEN | [2019/16] | English: | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | [2019/16] | French: | COMPOSÉS PYRIDINONE-PYRIDINYL SUBSTITUÉS | [2019/16] | Examination procedure | 17.10.2019 | Amendment by applicant (claims and/or description) | 17.10.2019 | Examination requested [2019/48] | 17.10.2019 | Date on which the examining division has become responsible | 03.03.2020 | Despatch of a communication from the examining division (Time limit: M04) | 06.07.2020 | Reply to a communication from the examining division | 28.09.2020 | Communication of intention to grant the patent | 21.01.2021 | Fee for grant paid | 21.01.2021 | Fee for publishing/printing paid | 21.01.2021 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP11847595.3 / EP2648516 | Opposition(s) | 06.12.2021 | No opposition filed within time limit [2022/06] | Fees paid | Renewal fee | 04.01.2019 | Renewal fee patent year 03 | 04.01.2019 | Renewal fee patent year 04 | 04.01.2019 | Renewal fee patent year 05 | 04.01.2019 | Renewal fee patent year 06 | 04.01.2019 | Renewal fee patent year 07 | 31.12.2018 | Renewal fee patent year 08 | 27.12.2019 | Renewal fee patent year 09 | 28.12.2020 | Renewal fee patent year 10 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 06.12.2011 | AL | 03.03.2021 | AT | 03.03.2021 | CY | 03.03.2021 | CZ | 03.03.2021 | DK | 03.03.2021 | EE | 03.03.2021 | FI | 03.03.2021 | HR | 03.03.2021 | LT | 03.03.2021 | LV | 03.03.2021 | MC | 03.03.2021 | MK | 03.03.2021 | MT | 03.03.2021 | NL | 03.03.2021 | PL | 03.03.2021 | RO | 03.03.2021 | RS | 03.03.2021 | SE | 03.03.2021 | SI | 03.03.2021 | SK | 03.03.2021 | SM | 03.03.2021 | TR | 03.03.2021 | BG | 03.06.2021 | NO | 03.06.2021 | GR | 04.06.2021 | IS | 03.07.2021 | PT | 05.07.2021 | [2026/04] |
| Former [2024/42] | HU | 06.12.2011 | |
| AL | 03.03.2021 | ||
| AT | 03.03.2021 | ||
| CY | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| MC | 03.03.2021 | ||
| MK | 03.03.2021 | ||
| MT | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SI | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2024/23] | HU | 06.12.2011 | |
| AL | 03.03.2021 | ||
| AT | 03.03.2021 | ||
| CY | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| MC | 03.03.2021 | ||
| MK | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SI | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2023/33] | HU | 06.12.2011 | |
| AL | 03.03.2021 | ||
| AT | 03.03.2021 | ||
| CY | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| MC | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SI | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2023/24] | AL | 03.03.2021 | |
| AT | 03.03.2021 | ||
| CY | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| MC | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SI | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2022/33] | AL | 03.03.2021 | |
| AT | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| MC | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SI | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2022/23] | AL | 03.03.2021 | |
| AT | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SI | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2022/13] | AL | 03.03.2021 | |
| AT | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SI | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| PT | 05.07.2021 | ||
| Former [2022/10] | AL | 03.03.2021 | |
| AT | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| PT | 05.07.2021 | ||
| Former [2022/08] | AL | 03.03.2021 | |
| AT | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| DK | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2022/07] | AL | 03.03.2021 | |
| AT | 03.03.2021 | ||
| CZ | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2021/51] | AT | 03.03.2021 | |
| CZ | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| IS | 03.07.2021 | ||
| PT | 05.07.2021 | ||
| Former [2021/50] | AT | 03.03.2021 | |
| CZ | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RO | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SK | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| PT | 05.07.2021 | ||
| Former [2021/48] | AT | 03.03.2021 | |
| CZ | 03.03.2021 | ||
| EE | 03.03.2021 | ||
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| Former [2021/46] | AT | 03.03.2021 | |
| FI | 03.03.2021 | ||
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| SM | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| Former [2021/43] | FI | 03.03.2021 | |
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| NL | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| Former [2021/39] | FI | 03.03.2021 | |
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| PL | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| Former [2021/38] | FI | 03.03.2021 | |
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| SE | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| Former [2021/37] | FI | 03.03.2021 | |
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| LV | 03.03.2021 | ||
| RS | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| Former [2021/36] | FI | 03.03.2021 | |
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| BG | 03.06.2021 | ||
| NO | 03.06.2021 | ||
| GR | 04.06.2021 | ||
| Former [2021/35] | FI | 03.03.2021 | |
| HR | 03.03.2021 | ||
| LT | 03.03.2021 | ||
| NO | 03.06.2021 | ||
| Former [2021/33] | FI | 03.03.2021 | |
| LT | 03.03.2021 | ||
| NO | 03.06.2021 | Documents cited: | Search | [A] WO03068230 (PHARMACIA CORP et al.) | [A] WO2005018557 (PHARMACIA CORP et al.) | [A] EP1741702 (ONO PHARMACEUTICAL CO et al.) | [A] EP1447401 (ONO PHARMACEUTICAL CO et al.) | [A] ESSA HU ET AL: "Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit +", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 11, 1 June 2008 (2008-06-01), pages 3065 - 3068, XP055108943, ISSN: 0022-2623, DOI: 10.1021/jm800188g DOI: http://dx.doi.org/10.1021/jm800188g | by applicant | WO0017175 | WO0071535 | WO0242292 | WO2008062905 | WO2005018557 | US2007167621 | WO2004087677 | WO2007081901 | WO2008153942 | US7067540 | US2005176775 | US7345054 | US2007003993 | DAVIDSON ET AL.: "Discovery and characterization of a substrate selective p38alpha inhibitor", BIOCHEMISTRY, vol. 43, 2004, pages 11658 - 11671 | BURNETTE ET AL.: "SD0006: a potent, selective and orally available inhibitor of p38 kinase", PHARMACOLOGY, vol. 84, no. 1, 2009, pages 42 - 60 |