| EP3473648 - HUMAN ANTIBODIES TO PD-L1 [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 08.04.2022 Database last updated on 08.04.2026 | |
| Former | The patent has been granted Status updated on 30.04.2021 | ||
| Former | Grant of patent is intended Status updated on 10.12.2020 | ||
| Former | Request for examination was made Status updated on 13.11.2020 | ||
| Former | Grant of patent is intended Status updated on 27.07.2020 | ||
| Former | Request for examination was made Status updated on 04.10.2019 | ||
| Former | The application has been published Status updated on 22.03.2019 | Most recent event Tooltip | 03.05.2024 | Lapse of the patent in a contracting state New state(s): MK | published on 05.06.2024 [2024/23] | Applicant(s) | For all designated states Regeneron Pharmaceuticals, Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | [2019/17] | Inventor(s) | 01 /
PAPADOPOULOS, Nicholas, J. c/o Regeneron Pharmaceuticals Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | 02 /
MURPHY, Andrew, J. c/o Regeneron Pharmaceuticals Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | 03 /
THURSTON, Gavin c/o Regeneron Pharmaceuticals Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | 04 /
IOFFE, Ella c/o Regeneron Pharmaceuticals Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | 05 /
BUROVA, Elena c/o Regeneron Pharmaceuticals Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591 / US | [2019/17] | Representative(s) | J A Kemp LLP 80 Turnmill Street London EC1M 5QU / GB | [N/P] |
| Former [2021/22] | J A Kemp LLP 14 South Square Gray's Inn London WC1R 5JJ / GB | ||
| Former [2019/17] | J A Kemp 14 South Square Gray's Inn London WC1R 5JJ / GB | Application number, filing date | 18206830.4 | 23.01.2015 | [2019/17] | Priority number, date | US201461930582P | 23.01.2014 Original published format: US 201461930582 P | US201462089549P | 09.12.2014 Original published format: US 201462089549 P | [2019/17] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3473648 | Date: | 24.04.2019 | Language: | EN | [2019/17] | Type: | B1 Patent specification | No.: | EP3473648 | Date: | 02.06.2021 | Language: | EN | [2021/22] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 11.02.2019 | Classification | IPC: | C07K16/28, C07K16/30, A61K39/395, C07K16/22, A61P35/00, A61P31/14, A61P31/18, A61P31/20, A61P37/02, // A61K39/00 | [2021/01] | CPC: |
C07K16/2827 (EP,EA,KR,US);
A61K39/3955 (EA,KR,US);
A61K39/39558 (EP,EA,KR,US);
A61K45/06 (EA,KR,US);
A61P31/14 (EP);
A61P31/18 (EP);
A61P31/20 (EP);
A61P35/00 (EP);
A61P37/02 (EP);
C07K16/22 (EP,EA,KR,US);
C07K16/30 (EP,EA,KR,US);
A61K2039/505 (EP,EA,US);
A61K2039/507 (EP,EA,US);
C07K2317/21 (EP,EA,KR,US);
C07K2317/565 (EA,KR,US);
| C-Set: |
A61K39/39558, A61K2300/00 (EP,US)
|
| Former IPC [2019/17] | C07K16/28, C07K16/30, A61K39/395, C07K16/22, A61P35/00, // A61K39/00 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2019/45] |
| Former [2019/17] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Extension states | BA | 30.09.2019 | ME | 30.09.2019 | Title | German: | MENSCHLICHE ANTIKÖRPER GEGEN PD-L1 | [2019/17] | English: | HUMAN ANTIBODIES TO PD-L1 | [2019/17] | French: | ANTICORPS HUMAINS DIRIGÉS CONTRE PD-L1 | [2019/17] | Examination procedure | 30.09.2019 | Examination requested [2019/45] | 30.09.2019 | Date on which the examining division has become responsible | 01.10.2019 | Amendment by applicant (claims and/or description) | 28.07.2020 | Communication of intention to grant the patent | 05.11.2020 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 11.12.2020 | Communication of intention to grant the patent | 20.04.2021 | Fee for grant paid | 20.04.2021 | Fee for publishing/printing paid | 20.04.2021 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP15703380.4 / EP3097120 | Opposition(s) | 03.03.2022 | No opposition filed within time limit [2022/19] | Fees paid | Renewal fee | 16.11.2018 | Renewal fee patent year 03 | 16.11.2018 | Renewal fee patent year 04 | 16.11.2018 | Renewal fee patent year 05 | 21.01.2020 | Renewal fee patent year 06 | 20.01.2021 | Renewal fee patent year 07 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | AL | 02.06.2021 | EE | 02.06.2021 | HR | 02.06.2021 | LT | 02.06.2021 | LV | 02.06.2021 | MK | 02.06.2021 | RO | 02.06.2021 | RS | 02.06.2021 | SI | 02.06.2021 | SK | 02.06.2021 | SM | 02.06.2021 | BG | 02.09.2021 | IS | 02.10.2021 | LU | 23.01.2022 | [2024/23] |
| Former [2022/46] | AL | 02.06.2021 | |
| EE | 02.06.2021 | ||
| HR | 02.06.2021 | ||
| LT | 02.06.2021 | ||
| LV | 02.06.2021 | ||
| RO | 02.06.2021 | ||
| RS | 02.06.2021 | ||
| SI | 02.06.2021 | ||
| SK | 02.06.2021 | ||
| SM | 02.06.2021 | ||
| BG | 02.09.2021 | ||
| IS | 02.10.2021 | ||
| LU | 23.01.2022 | ||
| Former [2022/29] | AL | 02.06.2021 | |
| EE | 02.06.2021 | ||
| HR | 02.06.2021 | ||
| LT | 02.06.2021 | ||
| LV | 02.06.2021 | ||
| RO | 02.06.2021 | ||
| RS | 02.06.2021 | ||
| SI | 02.06.2021 | ||
| SK | 02.06.2021 | ||
| SM | 02.06.2021 | ||
| BG | 02.09.2021 | ||
| IS | 02.10.2021 | ||
| Former [2022/26] | AL | 02.06.2021 | |
| EE | 02.06.2021 | ||
| HR | 02.06.2021 | ||
| LT | 02.06.2021 | ||
| LV | 02.06.2021 | ||
| RO | 02.06.2021 | ||
| RS | 02.06.2021 | ||
| SK | 02.06.2021 | ||
| SM | 02.06.2021 | ||
| BG | 02.09.2021 | ||
| IS | 02.10.2021 | ||
| Former [2022/10] | EE | 02.06.2021 | |
| HR | 02.06.2021 | ||
| LT | 02.06.2021 | ||
| LV | 02.06.2021 | ||
| RO | 02.06.2021 | ||
| RS | 02.06.2021 | ||
| SK | 02.06.2021 | ||
| SM | 02.06.2021 | ||
| BG | 02.09.2021 | ||
| IS | 02.10.2021 | ||
| Former [2022/07] | HR | 02.06.2021 | |
| LT | 02.06.2021 | ||
| LV | 02.06.2021 | ||
| RS | 02.06.2021 | ||
| SM | 02.06.2021 | ||
| BG | 02.09.2021 | ||
| Former [2021/51] | HR | 02.06.2021 | |
| LT | 02.06.2021 | ||
| LV | 02.06.2021 | ||
| RS | 02.06.2021 | ||
| BG | 02.09.2021 | ||
| Former [2021/49] | HR | 02.06.2021 | |
| LT | 02.06.2021 | ||
| LV | 02.06.2021 | ||
| BG | 02.09.2021 | ||
| Former [2021/46] | LT | 02.06.2021 | |
| BG | 02.09.2021 | Documents cited: | Search | [I] WO2010077634 (GENENTECH INC et al.) | by applicant | US7943742 | US8383796 | US8217149 | US2009055944 | US2012003056 | US2013034559 | US2013045200 | US2013045201 | US2013045202 | WO2007005874 | WO2011066389 | WO2010077634 | EP1907424 | EP1899379 | US6596541 | US201414170166 | US2004101920 | WO2005103081 | US201113022759 | US2010331527 | US8257740 | US8246995 | US7087411 | US2007280945 | US2014088295 | US2010203056 | DONG ET AL., NATURE MED., 1999 | CHEN ET AL., NATURE REV. IMMUNOL., vol. 13, 2013, pages 227 - 242 | FREEMAN, PNAS, vol. 105, 2008, pages 10275 - 10276 | FRANCISCO ET AL., IMMUNOL. REV., vol. 236, 2010, pages 219 - 242 | RIBAS, NEJM, vol. 366, 2012, pages 2517 - 2519 | SHERIDAN, NATURE BIOTECHNOLOGY, vol. 30, 2012, pages 729 - 730 | REDDY ET AL., J. IMMUNOL., vol. 164, 2000, pages 1925 - 1933 | KABAT: "Sequences of Proteins of Immunological Interest", 1991, NATIONAL INSTITUTES OF HEALTH | AL-LAZIKANI ET AL., J. MOL. BIOI., vol. 273, 1997, pages 927 - 948 | MARTIN ET AL., PROC. NATL. ACAD. SCI. USA, vol. 86, 1989, pages 9268 - 9272 | SHIELD ET AL., JBC, vol. 277, 2002, pages 26733 | "GenBank", Database accession no. NP_054862.1 | "GenBank", Database accession no. NP _005009.2 | "GenBank", Database accession no. NP_005182.1 | PADLAN ET AL., FASEB J., vol. 9, 1995, pages 133 - 139 | VAJDOS ET AL., J MOL BIOL, vol. 320, 2002, pages 415 - 428 | PEARSON, METHODS MOL. BIOL., vol. 24, 1994, pages 307 - 331 | GONNET ET AL., SCIENCE, vol. 256, 1992, pages 1443 45 | ALTSCHUL ET AL., J. MOL. BIOL., vol. 215, 1990, pages 403 - 410 | NUCLEIC ACIDS RES., vol. 25, 1997, pages 3389 - 3402 | LLOYD, SCIENCE AND TECHNOLOGY OF PHARMACEUTICAL COMPOUNDING, 1999 | HARLOW; LANE: "Antibodies", COLD SPRING HARBOR PRESS | REINEKE, METHODS MOL. BIOL., vol. 248, 2004, pages 443 - 63 | TOMER, PROT. SCI., vol. 9, 2000, pages 487 - 496 | EHRING, ANALYTICAL BIOCHEMISTRY, vol. 267, 1999, pages 252 - 259 | ENGEN; SMITH, ANAL. CHEM., vol. 73, 2001, pages 256A - 265A | JUNGHANS ET AL., CANCER RES., vol. 50, 1990, pages 1495 - 1502 | TUTT ET AL., J. IMMUNOL., vol. 147, 1991, pages 60 - 69 | KUFER ET AL., TRENDS BIOTECHNOL, vol. 22, 2004, pages 238 - 244 | KLEIN, MABS, vol. 4, no. 6, 2012, pages 1 - 11 | KAZANE ET AL., J. AM. CHEM. SOC., 4 December 2012 (2012-12-04) | POWELL ET AL.: "Compendium of excipients for parenteral formulations", J PHARM SCI TECHNOL, vol. 52, 1998, pages 238 - 311, XP009119027 | WU ET AL., J. BIOL. CHEM., vol. 262, 1987, pages 4429 - 4432 | LANGER, SCIENCE, vol. 249, 1990, pages 1527 - 1533 | ARRUEBO, M. ET AL.: "Antibody-conjugated nanoparticles for biomedical applications", J. NANOMAT., vol. 2009, 2009, pages 24 |