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Extract from the Register of European Patents

EP About this file: EP3582804

EP3582804 - PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  08.12.2023
Database last updated on 14.11.2024
FormerExamination is in progress
Status updated on  03.02.2023
FormerRequest for examination was made
Status updated on  22.11.2019
FormerThe international publication has been made
Status updated on  25.08.2018
Formerunknown
Status updated on  23.03.2018
Most recent event   Tooltip08.12.2023Application deemed to be withdrawnpublished on 10.01.2024  [2024/02]
Applicant(s)For all designated states
Polyphor AG
Hegenheimermattweg 125
4123 Allschwil / CH
[2019/52]
Inventor(s)01 / BAUER, Michael
Konrad-Adenauer-Strasse 32
79540 Lörrach / DE
02 / HOOFTMAN, Leon
Gempenweg 16
4414 Arlesheim / CH
03 / ROMAGNOLI, Barbara
Waldeckweg 24
CH-4102 Binningen / CH
 [2019/52]
Application number, filing date18709923.920.02.2018
[2019/52]
WO2018EP25042
Priority number, dateEP2017002005920.02.2017         Original published format: EP 17020059
[2019/52]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018149552
Date:23.08.2018
Language:EN
[2018/34]
Type: A1 Application with search report 
No.:EP3582804
Date:25.12.2019
Language:EN
The application published by WIPO in one of the EPO official languages on 23.08.2018 takes the place of the publication of the European patent application.
[2019/52]
Search report(s)International search report - published on:EP23.08.2018
ClassificationIPC:A61K39/00, A61K31/357, A61P35/00
[2019/52]
CPC:
A61K31/357 (EP,EA,IL,KR,US); A61K38/12 (KR,US); A61K38/10 (KR);
A61K9/0019 (US); A61P35/00 (EP,EA,KR,US); A61K2300/00 (IL,KR)
C-Set:
A61K31/357, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2019/52]
Extension statesBA19.09.2019
ME19.09.2019
Validation statesMA19.09.2019
TN19.09.2019
TitleGerman:PHARMAZEUTISCHE KOMBINATIONEN ZUR BEHANDLUNG VON KREBS[2019/52]
English:PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER[2019/52]
French:COMBINAISONS PHARMACEUTIQUES POUR TRAITER LE CANCER[2019/52]
Entry into regional phase19.09.2019National basic fee paid 
19.09.2019Designation fee(s) paid 
19.09.2019Examination fee paid 
Examination procedure19.09.2019Examination requested  [2019/52]
19.09.2019Date on which the examining division has become responsible
20.04.2020Amendment by applicant (claims and/or description)
07.02.2023Despatch of a communication from the examining division (Time limit: M06)
18.08.2023Application deemed to be withdrawn, date of legal effect  [2024/02]
07.09.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2024/02]
Fees paidRenewal fee
26.02.2020Renewal fee patent year 03
26.02.2021Renewal fee patent year 04
25.02.2022Renewal fee patent year 05
07.03.2023Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
28.02.202306   M06   Fee paid on   31.08.2023
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Cited inInternational search[XYI]  - Simon Sonia Pernas, "Dose escalation of POL6326 in combination with eribulin in HER2-negative relapsed metastatic breast cancer (mBCa) patients (pts).: Journal of Clinical Oncology: Vol 34, No 15_suppl", Journal of Clinical Oncology, doi:10.1200/JCO.2016.34.15_suppl.2548, (20160520), pages 2548 - 2548, URL: http://ascopubs.org/doi/abs/10.1200/JCO.2016.34.15_suppl.2548, (20180423), XP055469396 [X] 1-13,15,16 * the whole document * [Y] 1-16 [I] 1-16

DOI:   http://dx.doi.org/10.1200/JCO.2016.34.15_suppl.2548
 [Y]  - JINGYU XIANG ET AL, "Abstract 1114: Combination of a novel CXCR4 antagonist with chemotherapy reduces breast cancer bone metastatic tumor burden | Cancer Research", CANCER RESEARCH, (20141001), doi:10.1158/1538-7445.AM2014-1114, pages 114 - 114, XP055469478 [Y] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1158/1538-7445.AM2014-1114
 [Y]  - J. XIANG ET AL, "CXCR4 Protein Epitope Mimetic Antagonist POL5551 Disrupts Metastasis and Enhances Chemotherapy Effect in Triple-Negative Breast Cancer", MOLECULAR CANCER THERAPEUTICS, US, (20150812), vol. 14, no. 11, doi:10.1158/1535-7163.MCT-15-0252, ISSN 1535-7163, pages 2473 - 2485, XP055469472 [Y] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1158/1535-7163.MCT-15-0252
 [T]  - MARTA GIL-MARTIN ET AL, "Phase I study of the combination of balixafortide (CXCR4 inhibitor) and eribulin in HER2-negative metastatic breast cancer (MBC) patients (pts).: Journal of Clinical Oncology: Vol 35, No 15_suppl", JOURNAL OF CLINICAL ONCOLOGY, (20170520), vol. 35, no. 15, page 2555, XP055469882 [T] 1-16 * the whole document *
by applicant   - Eur J Ca, (20090000), vol. 45, pages 228 - 247
    - Clin Cancer Res, (20140000), vol. 20, no. 13, pages 3581 - 3588
    - SALGIA R; STILLE JR; WEAVER RW et al., "A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer", Lung Cancer, (20170000), vol. 105, doi:doi:10.1016/j.lungcan.2016.12.020, pages 7 - 13, XP029930951

DOI:   http://dx.doi.org/10.1016/j.lungcan.2016.12.020
    - CORTES J; O'SHAUGHNESSY J; LOESCH D et al., "Eribulin monotherapy versus treatment of physician's choice in patients with metastatic breast cancer (EMBRACE): a phase 3 open-label randomised study", Lancet, (20110000), vol. 377, no. 9769, doi:doi:10.1016/S0140-6736(11)60070-6, pages 914 - 923, XP055030961

DOI:   http://dx.doi.org/10.1016/S0140-6736(11)60070-6
    - KAUFMAN PA; AWADA A; TWELVES C et al., "Phase III open-label randomized study of eribulin mesylate versus capecitabine in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline and a taxane", Journal of clinical oncology: official journal of the American Society of Clinical Oncology, (20150000), vol. 33, no. 6, pages 594 - 601
    - CORTES J; VAHDAT L; BLUM JL et al., "Phase II study of the halichondrin B anolog eribulin mesylate in patients with locally advanced or metastatic breast cancer previously treated with an anthracycline, a taxane and capecitabine", Journal of clinical oncology: official journal of the American Society of Clinical Oncology, (20100000), vol. 28, no. 25, doi:doi:10.1200/JCO.2009.25.8467, pages 3922 - 3928, XP002678686

DOI:   http://dx.doi.org/10.1200/JCO.2009.25.8467
    - VAHDAT LT; PRUITT B; FABIAN CJ et al., "Phase II study of eribulin mesylate, a halichondrin B anolog, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane", Journal of clinical oncology: official journal of the American Society of Clinical Oncology, (20090000), vol. 27, no. 18, pages 2954 - 2961
    - SEYMOUR L; BOGAERTS J; PERRONE A et al., "iRECIST: guidelines for response criteria for use in trials testing immunotherapeut", Lancet Oncology, (20170000), vol. 18, no. 3, pages e143 - e152
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.