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Extract from the Register of European Patents

EP About this file: EP3585158

EP3585158 - RODENT MODELS OF RETINOSCHISIS [Right-click to bookmark this link]
Former [2020/01]NON-HUMAN ANIMAL MODELS OF RETINOSCHISIS
[2023/03]
StatusNo opposition filed within time limit
Status updated on  10.05.2024
Database last updated on 28.03.2026
FormerThe patent has been granted
Status updated on  02.06.2023
FormerGrant of patent is intended
Status updated on  17.01.2023
FormerExamination is in progress
Status updated on  29.10.2020
FormerRequest for examination was made
Status updated on  05.12.2019
FormerThe international publication has been made
Status updated on  01.09.2018
Formerunknown
Status updated on  24.03.2018
Most recent event   Tooltip19.12.2025Lapse of the patent in a contracting state
New state(s): TR		published on 21.01.2026  [2026/04]
Applicant(s)For all designated states
Regeneron Pharmaceuticals, Inc.
777 Old Saw Mill River Road
Tarrytown, NY 10591-6707 / US
[2020/01]
Inventor(s)01 / BRYDGES, Susannah
c/o Regeneron Pharmaceuticals Inc.
777 Old Saw Mill River Road
Tarrytown New York 10591-6707 / US
02 / TANG, Yajun
c/o Regeneron Pharmaceuticals Inc.
777 Old Saw Mill River Road
Tarrytown New York 10591-6707 / US
03 / LIU, Yang
c/o Regeneron Pharmaceuticals Inc.
777 Old Saw Mill River Road
Tarrytown New York 10591-6707 / US
04 / CAO, Jingtai
c/o Regeneron Pharmaceuticals Inc.
777 Old Saw Mill River Road
Tarrytown New York 10591-6707 / US
05 / ROMANO, Carmelo
c/o Regeneron Pharmaceuticals Inc.
777 Old Saw Mill River Road
Tarrytown New York 10591-6707 / US
 [2020/01]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[2023/27]
Former [2020/01]J A Kemp LLP
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date18710956.626.02.2018
[2020/01]
WO2018US19721
Priority number, dateUS201762463872P27.02.2017         Original published format: US 201762463872 P
US201762576256P24.10.2017         Original published format: US 201762576256 P
[2020/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018157058
Date:30.08.2018
Language:EN
[2018/35]
Type: A1 Application with search report 
No.:EP3585158
Date:01.01.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 30.08.2018 takes the place of the publication of the European patent application.
[2020/01]
Type: B1 Patent specification 
No.:EP3585158
Date:05.07.2023
Language:EN
[2023/27]
Search report(s)International search report - published on:EP30.08.2018
ClassificationIPC:A01K67/027, C12N15/85, G01N33/50, G01N33/68, C07K14/47, A61P27/02
[2023/03]
CPC:
A01K67/0276 (EP,KR,US); A01K67/0278 (EP,KR,US); A61K49/0008 (KR);
A61P27/02 (EP,KR); C07K14/47 (EP,KR,US); C12N15/8509 (KR,US);
G01N33/5088 (EP,KR,US); G01N33/6893 (EP,KR,US); A01K2217/054 (KR,US);
A01K2217/072 (EP,KR,US); A01K2217/075 (EP,KR,US); A01K2217/15 (EP,KR,US);
A01K2217/206 (EP,KR,US); A01K2227/105 (EP,KR,US); A01K2267/0306 (EP,KR,US);
A01K2267/0393 (EP,KR,US); C12N2015/8527 (KR,US); C12N2015/8536 (EP,KR,US);
C12N2510/00 (KR,US); C12N2800/30 (EP,KR,US); C12N2830/008 (EP,KR,US) (-)
Former IPC [2020/01]A01K67/027, G01N33/50, C07K14/47, C12N15/85
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/01]  
Extension statesBANot yet paid
MENot yet paid
Validation statesMANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:NAGETIERMODELLE VON RETINOSCHISIS[2023/03]
English:RODENT MODELS OF RETINOSCHISIS[2023/03]
French:MODÈLES DE RONGEURS DE RÉTINOSCHISIS[2023/03]
Former [2020/01]NICHTHUMANE TIERMODELLE VON RETINOSCHISIS
Former [2020/01]NON-HUMAN ANIMAL MODELS OF RETINOSCHISIS
Former [2020/01]MODÈLES D'ANIMAUX NON HUMAINS DE RÉTINOSCHISIS
Entry into regional phase21.08.2019National basic fee paid 
21.08.2019Designation fee(s) paid 
21.08.2019Examination fee paid 
Examination procedure09.04.2019Amendment by applicant (claims and/or description)
21.08.2019Examination requested  [2020/01]
21.08.2019Date on which the examining division has become responsible
28.10.2020Despatch of a communication from the examining division (Time limit: M04)
24.02.2021Reply to a communication from the examining division
25.06.2021Despatch of a communication from the examining division (Time limit: M04)
25.10.2021Reply to a communication from the examining division
22.03.2022Despatch of a communication from the examining division (Time limit: M04)
01.08.2022Reply to a communication from the examining division
18.01.2023Communication of intention to grant the patent
25.05.2023Fee for grant paid
25.05.2023Fee for publishing/printing paid
25.05.2023Receipt of the translation of the claim(s)
Opposition(s)08.04.2024No opposition filed within time limit [2024/24]
Fees paidRenewal fee
20.02.2020Renewal fee patent year 03
19.02.2021Renewal fee patent year 04
17.02.2022Renewal fee patent year 05
22.02.2023Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY26.02.2018
HU26.02.2018
CZ05.07.2023
HR05.07.2023
MC05.07.2023
PL05.07.2023
RO05.07.2023
RS05.07.2023
SK05.07.2023
SM05.07.2023
TR05.07.2023
NO05.10.2023
GR06.10.2023
IS05.11.2023
[2026/04]
Former [2025/41]CY26.02.2018
HU26.02.2018
CZ05.07.2023
HR05.07.2023
MC05.07.2023
PL05.07.2023
RO05.07.2023
RS05.07.2023
SK05.07.2023
SM05.07.2023
NO05.10.2023
GR06.10.2023
IS05.11.2023
Former [2025/37]CY26.02.2018
CZ05.07.2023
HR05.07.2023
MC05.07.2023
PL05.07.2023
RO05.07.2023
RS05.07.2023
SK05.07.2023
SM05.07.2023
NO05.10.2023
GR06.10.2023
IS05.11.2023
Former [2024/45]CZ05.07.2023
HR05.07.2023
MC05.07.2023
PL05.07.2023
RO05.07.2023
RS05.07.2023
SK05.07.2023
SM05.07.2023
NO05.10.2023
GR06.10.2023
IS05.11.2023
Former [2024/23]CZ05.07.2023
HR05.07.2023
PL05.07.2023
RO05.07.2023
RS05.07.2023
SK05.07.2023
SM05.07.2023
NO05.10.2023
GR06.10.2023
IS05.11.2023
Former [2024/20]HR05.07.2023
PL05.07.2023
RS05.07.2023
SM05.07.2023
NO05.10.2023
GR06.10.2023
IS05.11.2023
Former [2024/10]HR05.07.2023
PL05.07.2023
RS05.07.2023
NO05.10.2023
GR06.10.2023
IS05.11.2023
Former [2024/09]NO05.10.2023
GR06.10.2023
IS05.11.2023
Former [2024/08]NO05.10.2023
GR06.10.2023
Cited inInternational search[XYI] US2004261141  (WEBER BERNHARD HEINRICH FRIEDR et al.)
 [Y] WO2015021298  (REGENERON PHARMA et al.)
 [XP] CN107287243  (UNIV WENZHOU MEDICAL et al.)
 [Y]   FRANK M. DYKA ET AL: "Coexpression and Interaction of Wild-type and Missense RS1 Mutants Associated with X-Linked Retinoschisis: Its Relevance to Gene Therapy", INVESTIGATIVE OPTHALMOLOGY & VISUAL SCIENCE, vol. 48, no. 6, June 2007 (2007-06-01), US, pages 2491, XP055468249, ISSN: 1552-5783, DOI: 10.1167/iovs.06-1465

DOI:   http://dx.doi.org/10.1167/iovs.06-1465
 [Y]   ANNY DEVOY ET AL: "Genomically humanized mice: technologies and promises", NATURE REVIEWS GENETICS, vol. 13, 2012, pages 14 - 20, XP055126260, DOI: 10.1038/nrg3116

DOI:   http://dx.doi.org/10.1038/nrg3116
 [A]   RONALD A. BUSH ET AL: "Convergence of Human Genetics and Animal Studies: Gene Therapy for X-Linked Retinoschisis", COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, vol. 5, no. 8, 22 June 2015 (2015-06-22), pages a017368, XP055467803, DOI: 10.1101/cshperspect.a017368

DOI:   http://dx.doi.org/10.1101/cshperspect.a017368
 [A]   WINCO WING-HO WU: "RS1 STRUCTURE-FUNCTION RELATIONSHIPS: ROLES IN RETINAL ADHESION AND X-LINKED RETINOSCHISIS", October 2005 (2005-10-01), XP055468295, Retrieved from the Internet [retrieved on 20180418], DOI: 10.14288/1.0099862

DOI:   http://dx.doi.org/10.14288/1.0099862
by applicantUS8697851
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 US8946505
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 US7294754
 US2008078000
 US7612250
 US2004177390
 US2008092249
 WO9905266
 WO2008017234
 US2014235933
 US2014310828
 US6586251
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.