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Extract from the Register of European Patents

EP About this file: EP3618869

EP3618869 - COMPOSITIONS AND METHODS RELATED TO xCT ANTIBODIES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  03.03.2023
Database last updated on 02.11.2024
FormerRequest for examination was made
Status updated on  07.02.2020
FormerThe international publication has been made
Status updated on  09.11.2018
Most recent event   Tooltip03.03.2023Application deemed to be withdrawnpublished on 05.04.2023  [2023/14]
Applicant(s)For all designated states
Agilvax, Inc.
5901 Indian School Road NE
Albuquerque, NM 87110 / US
[2020/11]
Inventor(s)01 / PERICLE, Federica
5901 Indian School Road N.E.
Albuquerque, NM 87110 / US
02 / O'ROURKE, John
5901 Indian School Road N.E.
Albuquerque, NM 87110 / US
03 / CAVALLO, Federica
5901 Indian School Road N.E.
Albuquerque, NM 87110 / US
 [2020/11]
Representative(s)Forresters IP LLP
Skygarden
Erika-Mann-Straße 11
80636 München / DE
[N/P]
Former [2020/11]Bond, Christopher William
Forresters IP LLP
Skygarden
Erika-Mann-Strasse 11
80636 München / DE
Application number, filing date18794274.330.04.2018
[2020/11]
WO2018US30276
Priority number, dateUS201762492912P01.05.2017         Original published format: US 201762492912 P
[2020/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018204278
Date:08.11.2018
Language:EN
[2018/45]
Type: A1 Application with search report 
No.:EP3618869
Date:11.03.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 08.11.2018 takes the place of the publication of the European patent application.
[2020/11]
Search report(s)International search report - published on:US08.11.2018
(Supplementary) European search report - dispatched on:EP22.12.2020
ClassificationIPC:C07K16/18, C07K16/30, C07K16/46, A61K39/395
[2021/03]
CPC:
C07K16/3015 (EP,US); C07K16/18 (EP); C07K2317/24 (US);
C07K2317/622 (US)
Former IPC [2020/11]A61K39/395, C07K16/46, C07K16/30
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/11]
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN IM ZUSAMMENHANG MIT XCT-ANTIKÖRPERN[2020/11]
English:COMPOSITIONS AND METHODS RELATED TO xCT ANTIBODIES[2020/11]
French:COMPOSITIONS ET MÉTHODES RELATIVES À DES ANTICORPS xCT[2020/11]
Entry into regional phase17.10.2019National basic fee paid 
17.10.2019Search fee paid 
17.10.2019Designation fee(s) paid 
17.10.2019Examination fee paid 
Examination procedure17.10.2019Examination requested  [2020/11]
03.11.2021Amendment by applicant (claims and/or description)
01.11.2022Application deemed to be withdrawn, date of legal effect  [2023/14]
24.11.2022Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2023/14]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
03.11.2021Request for further processing filed
03.11.2021Full payment received (date of receipt of payment)
Request granted
12.11.2021Decision despatched
Fees paidRenewal fee
30.09.2020Renewal fee patent year 03
22.04.2021Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
30.04.202003   M06   Fee paid on   30.09.2020
30.04.202205   M06   Not yet paid
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Documents cited:Search[I]CN105837686  (LUOYANG PULAI PULAIKE WANTAI BIOTECHNOLOGY CO LTD) [I] 2 * abstract *;
 [I]WO2017052679  (THE US SECRETARY DEPARTMNET OF HEALTH & HUMAN SERVICE [US]) [I] 3 * abstract *;
 [AP]WO2017106806  (CAVALLO FEDERICA [IT], et al) [AP] 1-15 * abstract *;
 [I]  - TAKATSUGU ISHIMOTO ET AL, "CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xcand Thereby Promotes Tumor Growth", CANCER CELL, CELL PRESS, US, vol. 19, no. 3, doi:10.1016/J.CCR.2011.01.038, ISSN 1535-6108, (20110113), pages 387 - 400, (20110129), XP028162421 [I] 1-15 * abstract * * page 388, column left, paragraph 1st full * * page 392, column right, paragraph 1st full - page 395; figure 5 * * page 396, paragraph last - page 397, paragraph 1st; figure 8 *

DOI:   http://dx.doi.org/10.1016/j.ccr.2011.01.038
 [I]  - VAN LIEFFERINGE JOERI ET AL, "Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed.", THE JOURNAL OF COMPARATIVE NEUROLOGY 01 APR 2016, (20160401), vol. 524, no. 5, ISSN 1096-9861, pages 1015 - 1032, XP009524374 [I] 1-9 * abstract * * page 1023 *

DOI:   http://dx.doi.org/10.1002/cne.23889
    [ ] - MASSIE ANN ET AL, "Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats", NEUROREPORT, (200810), vol. 19, no. 16, ISSN 0959-4965, pages 1589 - 1592, XP055756000 [ ] * abstract * * page 1590, column left - page 1592; figure 1 *

DOI:   http://dx.doi.org/10.1097/WNR.0b013e328312181c
 [AP]  - O'ROURKE JOHN ET AL, "AX09: an immunotherapy candidate targeting the breast cancer stem cell protein xCT", CANCER RESEARCH, & ANNUAL MEETING OF THE AMERICAN-ASSOCIATION-FOR-CANCER-RESEARCH (AACR); WASHINGTON, DC, USA; APRIL 01 -05, 2017, (201707), vol. 77, no. Suppl. 13, ISSN 0008-5472, page 5572, XP009524371 [AP] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1158/1538-7445.AM2017-5572
 [T]  - Anonymous, "SLC7A11 - Cystine/glutamate transporter - Homo sapiens (Human) - SLC7A11 gene & protein", (20000501), URL: https://www.uniprot.org/uniprot/Q9UPY5, (20201202), XP055755970
International search[A]US2003224454  (RYSECK ROLF PETER [US], et al) [A] 1-17 * ; abstract; paragraphs [0006]-[0007], [0073] *;
 [A]US2007087006  (FRANTZ GRETCHEN [US], et al) [A] 1-17 * ; abstract; paragraphs [0006], [0040] *;
 [AP]WO2017106806  (CAVALLO FEDERICA [IT], et al) [AP] 1-17 * ; whole document *
 [A]  - SHIH, A et al., "xCT Cystine Transporter Expression in HEK293 Cells: Pharmacology and Localization", Biochemical and Biophysical Research Communications, (20010420), vol. 282, no. 5, pages 1132 - 1137, XP055545116 [A] 1-17 * ; page 1135, column 2, paragraph 2; Genbank supplement pages 1-4; DOI: 10.1006/bbrc.2001.4703 *

DOI:   http://dx.doi.org/10.1006/bbrc.2001.4703
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.