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Extract from the Register of European Patents

EP About this file: EP3713573

EP3713573 - IRON CHELATORS IN TUMOR THERAPY [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  09.05.2024
Database last updated on 04.11.2024
FormerRequest for examination was made
Status updated on  28.08.2020
FormerThe international publication has been made
Status updated on  01.06.2019
Formerunknown
Status updated on  07.12.2018
Most recent event   Tooltip04.09.2024Change: Despatch of examination report + time limit 
Applicant(s)For all designated states
Deutsches Krebsforschungszentrum
Im Neuenheimer Feld 280
69120 Heidelberg / DE
[2020/40]
Inventor(s)01 / HOPPE-SEYLER, Felix
Weinheimer Str. 7
69493 Hirschberg / DE
02 / BRAUN, Julia A.
Amselweg 4
68535 Edingen-Neckarhausen / DE
03 / HOPPE-SEYLER, Karin
Weinheimer Strasse 7
69493 Hirschberg / DE
 [2020/40]
Representative(s)Altmann Stößel Dick Patentanwälte PartG mbB
Theodor-Heuss-Anlage 2
68165 Mannheim / DE
[N/P]
Former [2020/40]Altmann Stößel Dick Patentanwälte PartG mbB
Dudenstrasse 46
68167 Mannheim / DE
Application number, filing date18807975.023.11.2018
[2020/40]
WO2018EP82316
Priority number, dateEP2017020339123.11.2017         Original published format: EP 17203391
[2020/40]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019101897
Date:31.05.2019
Language:EN
[2019/22]
Type: A1 Application with search report 
No.:EP3713573
Date:30.09.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 31.05.2019 takes the place of the publication of the European patent application.
[2020/40]
Search report(s)International search report - published on:EP31.05.2019
ClassificationIPC:A61K31/4412, A61K31/16, A61K31/444, A61P35/00
[2020/40]
CPC:
A61K31/4412 (EP,US); A61K31/4418 (US); A61K31/16 (EP,US);
A61K31/345 (US); A61K31/4196 (US); A61K31/44 (US);
A61K31/444 (EP,US); A61K45/06 (US); A61P35/00 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/40]
TitleGerman:EISENCHELATOREN IN DER TUMORTHERAPIE[2020/40]
English:IRON CHELATORS IN TUMOR THERAPY[2020/40]
French:CHÉLATEURS DU FER EN THÉRAPIE ANTITUMORALE[2020/40]
Entry into regional phase27.04.2020National basic fee paid 
27.04.2020Designation fee(s) paid 
27.04.2020Examination fee paid 
Examination procedure23.09.2019Request for preliminary examination filed
International Preliminary Examining Authority: EP
27.04.2020Examination requested  [2020/40]
27.04.2020Date on which the examining division has become responsible
08.01.2021Amendment by applicant (claims and/or description)
08.05.2024Despatch of a communication from the examining division (Time limit: M06)
Fees paidRenewal fee
19.11.2020Renewal fee patent year 03
19.11.2021Renewal fee patent year 04
18.11.2022Renewal fee patent year 05
23.11.2023Renewal fee patent year 06
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Cited inInternational search[X]  - WEEMS JESSICA M ET AL, "Abstract 914: Ciclopirox olamine (CPX) inhibits breast cancer cell proliferation by blocking the formation of a PEAK1-Src-eIF5a protein complex", CANCER RESEARCH, & 103RD ANNUAL MEETING OF THE AMERICAN-ASSOCIATION-FOR-CANCER-RESEARCH; CHICAGO, IL, USA; MARCH 31 -APRIL 04, 2012, (201204), vol. 72, no. Suppl. 8, doi:10.1158/1538-7445.AM2012-914, XP002779248 [X] 1-8 * abstract *

DOI:   http://dx.doi.org/10.1158/1538-7445.AM2012-914
 [X]  - SHEN TAO ET AL, "Abstract 3408: The anticancer mechanisms of ciclopirox olamine.", CANCER RESEARCH, & 104TH ANNUAL MEETING OF THE AMERICAN-ASSOCIATION-FOR-CANCER-RESEARCH (AACR); WASHINGTON, DC, USA; APRIL 06 -10, 2013, (201304), vol. 73, no. 8, Suppl. 1, doi:10.1158/1538-7445.AM2013-3408, XP002779249 [X] 1-8 * abstract *

DOI:   http://dx.doi.org/10.1158/1538-7445.AM2013-3408
 [X]  - ZHOU HONGYU ET AL, "The antitumor activity of the fungicide ciclopirox", INTERNATIONAL JOURNAL OF CA, JOHN WILEY & SONS, INC, US, (20100101), vol. 127, no. 10, ISSN 0020-7136, pages 2467 - 2477, XP008132831 [X] 1-8 * page 2467, abstract *
 [X]  - YANINA EBERHARD ET AL, "Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 114, no. 14, doi:10.1182/BLOOD-2009-03-209965, ISSN 0006-4971, (20091001), pages 3064 - 3073, (20090709), XP009152199 [X] 1-8 * page 3064, abstract *

DOI:   http://dx.doi.org/10.1182/blood-2009-03-209965
 [X]  - FRYKNAS MARTEN ET AL, "Iron chelators target both proliferating and quiescent cancer cells", SCIENTIFIC REPORTS, (20161207), vol. 6, doi:10.1038/srep38343, XP002779250 [X] 1-8 * page 1, abstract *

DOI:   http://dx.doi.org/10.1038/srep38343
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    - SONG et al., Cancer Res., (20110000), vol. 71, pages 7628 - 7639
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    - DYSON et al., Science, (19890000), vol. 243, no. 4893, pages 934 - 7
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    - HALL; ALEXANDER, J Viral, (20030000), vol. 77, no. 10, pages 6066 - 9
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    - HOPPE-SEYLER et al., Proceedings of the National Academy of Sciences, (20170000), vol. 114, no. 6, pages E990 - E998
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    - HILI et al., Sem in Radial Oncol, (20150000), vol. 25, no. 4, pages 260 - 72
    - MANOOCHEHRI KHOSHINANI et al., Cancer Invest, (20160000), vol. 34, no. 10, pages 536 - 545
    - SHEN; HUANG, Curr Pharm Des, (20160000), vol. 22, no. 28, pages 4443 - 50
    - ZHOU et al., Journal international du cancer, (20100000), vol. 127, no. 10, pages 2467 - 2477
    - EBERHARD et al., Blood, (20090000), vol. 114, no. 14, pages 3064 - 3073
    - CHEMICAL ABSTRACTS, Database accession no. 29342-05-0
    - CHEMICAL ABSTRACTS, Database accession no. 70-51-9
    - CHEMICAL ABSTRACTS, Database accession no. 127-07-1
    - CHEMICAL ABSTRACTS, Database accession no. 59-87-0
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DOI:   http://dx.doi.org/10.1016/j.virol.2004.03.033
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    - HILI et al., Sem In Radial Oncol, (20150000), vol. 25, no. 4, pages 260 - 72
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.