blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP3634478

EP3634478 - METHODS OF SUPPRESSING MICROGLIAL ACTIVATION [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  23.09.2022
Database last updated on 29.06.2024
FormerRequest for examination was made
Status updated on  13.03.2020
FormerThe international publication has been made
Status updated on  15.12.2018
Most recent event   Tooltip28.06.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
The Brigham and Women's Hospital, Inc.
75 Francis Street
Boston, MA 02115 / US
[2020/16]
Inventor(s)01 / BUTOVSKY, Oleg
117 Park Drive
Apt. No. 1
Boston, Massachusetts 02215 / US
02 / WEINER, Howard
72 Colbourne Crescent
Brookline, Massachusetts 02445 / US
 [2020/16]
Representative(s)Forresters IP LLP
Skygarden
Erika-Mann-Straße 11
80636 München / DE
[N/P]
Former [2020/16]Donald, Jenny Susan
Forresters IP LLP
Skygarden
Erika-Mann-Strasse 11
80636 München / DE
Application number, filing date18813852.306.06.2018
[2020/16]
WO2018US36261
Priority number, dateUS201762515711P06.06.2017         Original published format: US 201762515711 P
[2020/16]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018226833
Date:13.12.2018
Language:EN
[2018/50]
Type: A1 Application with search report 
No.:EP3634478
Date:15.04.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 13.12.2018 takes the place of the publication of the European patent application.
[2020/16]
Search report(s)International search report - published on:US13.12.2018
(Supplementary) European search report - dispatched on:EP22.02.2021
ClassificationIPC:A61K39/00, A61K39/395, A61P9/10, A61P25/00, A61P25/28, C07K16/28, A61P37/06
[2021/12]
CPC:
A61P25/00 (EP); C07K16/2809 (EP,US); A61P25/28 (EP);
A61P37/06 (EP); A61P9/10 (EP); A61K2039/505 (US);
A61K2039/543 (EP,US); A61K2039/55 (EP); C07K2317/55 (EP) (-)
Former IPC [2020/16]A61K39/00, A61K39/395, A61P9/10, A61P25/00, A61P25/28, C07K16/28
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/16]
TitleGerman:VERFAHREN ZUR UNTERDRÜCKUNG DER MIKROGLIA-AKTIVIERUNG[2020/16]
English:METHODS OF SUPPRESSING MICROGLIAL ACTIVATION[2020/16]
French:MÉTHODES D'INHIBITION DE L'ACTIVATION MICROGLIALE[2020/16]
Entry into regional phase11.12.2019National basic fee paid 
11.12.2019Search fee paid 
11.12.2019Designation fee(s) paid 
11.12.2019Examination fee paid 
Examination procedure11.12.2019Examination requested  [2020/16]
22.09.2021Amendment by applicant (claims and/or description)
26.09.2022Despatch of a communication from the examining division (Time limit: M04)
06.02.2023Reply to a communication from the examining division
Fees paidRenewal fee
29.06.2020Renewal fee patent year 03
28.06.2021Renewal fee patent year 04
27.06.2022Renewal fee patent year 05
27.06.2023Renewal fee patent year 06
27.06.2024Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]US2010209437  (ELSON GREG [FR], et al) [A] 1-15* example all *;
 [I]  - LIOR MAYO ET AL, "IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation", BRAIN, GB, (20160531), vol. 139, no. 7, doi:10.1093/brain/aww113, ISSN 0006-8950, pages 1939 - 1957, XP055556301 [I] 1-15 * page 1950 - page 1952; figure 7 *

DOI:   http://dx.doi.org/10.1093/brain/aww113
International search[X]US2010209437  (ELSON GREG [FR], et al) [X] 6, 9, 10, 16 * entire document *;
 [A]US2011021413  (LASKOWITZ DANIEL T [US], et al) [A] 1-17* entire document *;
 [XY]  - MAYO et al., "IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation", Brain, (20160531), vol. 139, no. 7, pages 1939 - 1957, XP055556301 [X] 1-4, 6-9, 17 * and Supplementary Materials Pgs. 1-54. entire document * [Y] 11-15

DOI:   http://dx.doi.org/10.1093/brain/aww113
 [Y]  - ZHAO et al., "Hippo/MST1 signaling mediates microglial activation following acute cerebral ischemia-reperfusion injury", Brain Behav Immun, (20151222), vol. 55, pages 236 - 248, XP029571837 [Y] 11, 12 * , Pgs. 236-248. entire document. *

DOI:   http://dx.doi.org/10.1016/j.bbi.2015.12.016
 [Y]  - BRODY et al., "The pathophysiology of repetitive concussive traumatic brain injury in experimental models; new developments and open questions", Mol Cell Neurosci, (20150213), vol. 66, pages 91 - 98, XP055556311 [Y] 13, 14 * . entire document *

DOI:   http://dx.doi.org/10.1016/j.mcn.2015.02.005
 [Y]  - PRESSEY et al., "Early glial activation, synaptic changes and axonal pathology in the thalamocortical system of Niemann-Pick type C1 mice", Neurobiol Dis, (20120300), vol. 45, no. 3, pages 1086 - 1100, XP055556322 [Y] 15 * . entire document *

DOI:   http://dx.doi.org/10.1016/j.nbd.2011.12.027
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.