blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP3641757

EP3641757 - COMPOSITION, USES, AND METHODS OF TREATING SPINAL DISC DEGENERATION THROUGH SONIC HEDGEHOG SIGNALING PATHWAY [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  16.02.2024
Database last updated on 01.10.2024
FormerRequest for examination was made
Status updated on  27.03.2020
FormerThe international publication has been made
Status updated on  31.12.2018
Most recent event   Tooltip15.06.2024New entry: Reply to examination report 
Applicant(s)For all designated states
New York Society for the Relief of the Ruptured and Crippled, maintaining the Hospital for Special Surgery
535 East 70th Street
New York, NY 10021 / US
[2023/27]
Former [2020/18]For all designated states
New York Society for the Ruptured and Crippled Maintaining the Hospital for Special Surgery
535 East 70th Street
New York, NY 10021 / US
Inventor(s)01 / DAHIA, Chitra
535 East 70th Street
New York NY 10021 / US
 [2020/18]
Representative(s)Kilburn & Strode LLP
Lacon London
84 Theobalds Road
Holborn
London WC1X 8NL / GB
[N/P]
Former [2020/18]Cornish, Kristina Victoria Joy, et al
Kilburn & Strode LLP
Lacon London
84 Theobalds Road
London WC1X 8NL / GB
Application number, filing date18821602.223.06.2018
[2020/18]
WO2018US39178
Priority number, dateUS201762524121P23.06.2017         Original published format: US 201762524121 P
US201862631184P15.02.2018         Original published format: US 201862631184 P
[2020/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2018237368
Date:27.12.2018
Language:EN
[2018/52]
Type: A1 Application with search report 
No.:EP3641757
Date:29.04.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 27.12.2018 takes the place of the publication of the European patent application.
[2020/18]
Search report(s)International search report - published on:US27.12.2018
(Supplementary) European search report - dispatched on:EP18.02.2021
ClassificationIPC:A61K31/395, A61K31/416, A61K31/4166, A61K31/4535, A61K31/5377, A61K31/573
[2021/12]
CPC:
A61K31/4436 (EP,US); A61K31/381 (EP); A61K31/4535 (EP);
A61K31/5377 (EP); A61K31/573 (EP); A61K45/06 (EP,US);
A61P21/00 (US) (-)
Former IPC [2020/18]A61K31/395, A61K31/416, A61K31/4166
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/18]
TitleGerman:ZUSAMMENSETZUNG, VERWENDUNGEN UND VERFAHREN ZUR BEHANDLUNG VON BANDSCHEIBENDEGENERATION DURCH EINEN HEDGEHOG-SCHALLSIGNALWEG[2020/18]
English:COMPOSITION, USES, AND METHODS OF TREATING SPINAL DISC DEGENERATION THROUGH SONIC HEDGEHOG SIGNALING PATHWAY[2020/18]
French:COMPOSITION, UTILISATIONS ET MÉTHODES DE TRAITEMENT DE LA DÉGÉNÉRESCENCE DU DISQUE VERTÉBRAL PAR L'INTERMÉDIAIRE D'UNE VOIE DE SIGNALISATION SONIC HEDGEHOG[2020/18]
Entry into regional phase21.01.2020National basic fee paid 
21.01.2020Search fee paid 
21.01.2020Designation fee(s) paid 
21.01.2020Examination fee paid 
Examination procedure21.01.2020Examination requested  [2020/18]
20.09.2021Amendment by applicant (claims and/or description)
16.02.2024Despatch of a communication from the examining division (Time limit: M04)
14.06.2024Reply to a communication from the examining division
Fees paidRenewal fee
30.06.2020Renewal fee patent year 03
08.06.2021Renewal fee patent year 04
31.03.2022Renewal fee patent year 05
31.03.2023Renewal fee patent year 06
31.03.2024Renewal fee patent year 07
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]  - DAHIA C ET AL, "In Vitro Model System to Study Mouse Intervertebral Disc Growth", THE SPINE JOURNAL, ELSEVIER, AMSTERDAM, NL, vol. 10, no. 9, ISSN 1529-9430, (20100901), page S138, (20100901), XP027272495 [A] 1-15 * the whole document *
 [A]  - M. KYLE HADDEN, "Hedgehog Pathway Agonism: Therapeutic Potential and Small-Molecule Development", CHEMMEDCHEM, DE, (20131107), vol. 9, no. 1, doi:10.1002/cmdc.201300358, ISSN 1860-7179, pages 27 - 37, XP055628960 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1002/cmdc.201300358
International search[A]US2004230309  (DIMAURO THOMAS M [US], et al) [A] 1-3, 29-31, 43-49 * Entire Document *;
 [A]US2008138379  (JENNINGS-SPRING BARBARA L [US]) [A] 1-3, 29-31, 43-49 * Entire Document *;
 [A]US2011172233  (PENG LEE F [US], et al) [A] 1-3, 29-31, 43-49* Entire Document *;
 [A]US2014275025  (ANDERSKEWITZ RALF [DE], et al) [A] 1-3, 29-31, 43-49 * Entire Document *;
 [YA]US2016143984  (CHEN GONG [US], et al) [Y] 2, 16, 30, 49 * Para [0033]; Para [0044]; Para [0056]; * [A] 17/16;
 [YA]US2017065745  (BROWN LAURA J [US], et al) [Y] 1-2, 15-16, 29-30, 43-49 * Para [0003]; Para [0013];Para [0014]; Para [0015]; Para [0020]; Para [0048]; Para [0050]; Para [0095]; Para [0097]; * [A] 3, 17/15, 17/16, 31;
 [YA]  - DAHIA et al., "Shh Signaling from the Nucleus Pulposus Is Required for the Postnatal Growth and Differentiation of the Mouse Intervertebral Disc", PLoS One, (20120400), vol. 7, no. 4, pages 1 - 15, XP055555501 [Y] 1-2, 15-16, 29-30, 43-49 * Pg. 1, Abstract; Pg. 2, Col.2, Para [2]; Pg. 3, Col. 2, Para [1]; Pg. 8, Col. 1, Para [2]; Pg. 10, Col. 2, Para [1]; Pg. 11, Col. 1, Para [1]; * [A] 3, 17/15, 17/16, 31

DOI:   http://dx.doi.org/10.1371/journal.pone.0035944
 [A]  - RISBUD et al., "Notochordal Cells in the Adult Intervertebral Disc: New Perspective on an Old Question", Crit Rev Eukaryot Gene Expr., (20110000), vol. 21, no. 1, pages 29 - 41, XP055660976 [A] 3, 17/15, 17/16, 31 * Pg. 6, Para [1]; Pg. 6, Para [2]; *

DOI:   http://dx.doi.org/10.1615/CritRevEukarGeneExpr.v21.i1.30
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.