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Extract from the Register of European Patents

EP About this file: EP3689355

EP3689355 - PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LIVER CANCER [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  03.07.2020
Database last updated on 31.08.2024
FormerThe international publication has been made
Status updated on  02.02.2019
Most recent event   Tooltip15.05.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Lemonex Inc.
Sillim-dong
Seoul National University
1 Gwanak-ro
Gwanak-gu
Seoul 08826 / KR
[2020/32]
Inventor(s)01 / WON, Cheol Hee
(Nakseongdae Hyundai Hometown
Bongcheon-dong) 301-803
16 Solbat-ro 7-gil
Gwanak-gu
Seoul 08741 / KR
 [2020/32]
Representative(s)dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[2020/32]
Application number, filing date18838318.630.07.2018
[2020/32]
WO2018KR08611
Priority number, dateUS201762538034P28.07.2017         Original published format: US 201762538034 P
[2020/32]
Filing languageKO
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2019022586
Date:31.01.2019
Language:KO
[2019/05]
Type: A2 Application without search report 
No.:EP3689355
Date:05.08.2020
Language:EN
[2020/32]
Search report(s)International search report - published on:KR04.07.2019
(Supplementary) European search report - dispatched on:EP10.08.2021
ClassificationIPC:C12N15/113, A61K31/713, A61K9/51, A61P35/00
[2021/18]
CPC:
C12N15/111 (EP); A61K48/00 (KR); A61K31/713 (EP,CN,US);
A61K31/715 (KR); A61K47/02 (CN); A61K9/0019 (EP);
A61K9/143 (EP); A61K9/51 (EP); A61K9/5115 (EP,KR);
A61P1/16 (EP); A61P35/00 (EP,CN,KR,US); C12N15/113 (EP,US);
C12N15/1135 (CN,US); C12N2310/14 (EP,CN,US); C12N2320/32 (EP,CN) (-)
Former IPC [2020/32]A61K31/713, A61K9/51, A61P35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/32]
TitleGerman:PHARMAZEUTISCHE ZUSAMMENSETZUNG ZUR VORBEUGUNG ODER BEHANDLUNG VON LEBERKREBS[2020/32]
English:PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING LIVER CANCER[2020/32]
French:TRAITEMENTS PHARMACEUTIQUES POUR PRÉVENIR OU TRAITER LE CANCER DU FOIE[2020/32]
Entry into regional phase25.02.2020Translation filed 
25.02.2020National basic fee paid 
25.02.2020Search fee paid 
25.02.2020Designation fee(s) paid 
25.02.2020Examination fee paid 
Examination procedure25.02.2020Examination requested  [2020/32]
04.03.2022Amendment by applicant (claims and/or description)
Fees paidRenewal fee
29.07.2020Renewal fee patent year 03
29.07.2021Renewal fee patent year 04
28.07.2022Renewal fee patent year 05
27.07.2023Renewal fee patent year 06
15.05.2024Renewal fee patent year 07
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[I]WO2005116204  (RNAI CO LTD [JP], et al) [I] 1-15 * sequences 22171,455895,222229-222245 *;
 [I]WO2009079452  (BRIGHAM & WOMENS HOSPITAL [US], et al) [I] 1,2,5,7-15 * page 71; claim 1; sequence 936 *;
 [A]WO2009080898  (OULUN YLIOPISTO [FI], et al) [A] 1,2,5,7-15;
 [I]WO2009140676  (IMMUNE DISEASE INST INC [US], et al) [I] 1-4,7-14 * page 69; sequence 52 *;
 [I]WO2010134939  (ZIRUS INC [US], et al) [I] 1,2,5,7-15 * page 74; sequences 1839-1840 *;
 [A]WO2012139081  (UNIV LEICESTER [GB], et al) [A] 1-15;
 [I]KR20170023335  (KOREA INST RADIOLOGICAL & MEDICAL SCIENCES [KR]) [I] 1,2,5,7-15 * claim 4; sequence 4 *;
 [A]  - LEE SO JIN ET AL, "Delivery strategies and potential targets for siRNA in major cancer types", ADVANCED DRUG DELIVERY REVIEWS, ELSEVIER, AMSTERDAM , NL, (20160531), vol. 104, doi:10.1016/J.ADDR.2016.05.010, ISSN 0169-409X, pages 2 - 15, XP029651118 [A] 1-15

DOI:   http://dx.doi.org/10.1016/j.addr.2016.05.010
 [IP]  - QINGYU SHEN ET AL, "Barrier to autointegration factor 1, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, and splicing factor 3b subunit 4 as early-stage cancer decision markers and drivers of hepatocellular carcinoma : Shen, Eun, et al.", HEPATOLOGY, (20180401), vol. 67, no. 4, doi:10.1002/hep.29606, ISSN 0270-9139, pages 1360 - 1377, XP055630132 [IP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1002/hep.29606
 [P]  - Shen Qingyu; ET AL, "Supporting Information BANF1, PLOD3, SF3B4 as Early-stage Cancer Decision Markers and Drivers of Hepatocellular Carcinoma Supplementary Material and Methods CELL CULTURE", (20180401), URL: https://aasldpubs.onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1002%2Fhep.29606&file=hep29606-sup-0001-suppinfo1.pdf, (20210309), XP055783287
 [I]  - MAO LANGYONG ET AL, "BANF1 Is Downregulated by IRF1-Regulated MicroRNA-203 in Cervical Cancer", PLOS ONE, vol. 10, no. 2, doi:10.1371/journal.pone.0117035, (20150206), page e0117035, URL: https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0117035/1/pone.0117035.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa@plos-prod.iam.gserviceaccount.com/20210304/auto/storage/goog4_request&X-Goog-Date=20210304T134354Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=ho, XP055782167 [I] 1-4,7-14 * figures 6,7 *

DOI:   http://dx.doi.org/10.1371/journal.pone.0117035
    [ ] - Anonymous, "WO 2005116204-A/22171: Double strand polynucleotides generating RNA in - Nucleotide - NCBI", (20110418), URL: https://www.ncbi.nlm.nih.gov/nuccore/FW615645.1, XP055783046
    [ ] - Anonymous, "WO 2005116204-A/455895: Double strand polynucleotides generating RNA i - Nucleotide - NCBI", (20110419), URL: https://www.ncbi.nlm.nih.gov/nuccore/FZ049370.1, XP055783051
    [ ] - Anonymous, "WO 2005116204-A/46962: Double strand polynucleotides generating RNA in - Nucleotide - NCBI", (20110418), URL: https://www.ncbi.nlm.nih.gov/nuccore/FW640436, (20210630), XP055819800
    [ ] - Anonymous, "WO 2005116204-A/46963: Double strand polynucleotides generating RNA in - Nucleotide - NCBI", (20110418), URL: https://www.ncbi.nlm.nih.gov/nuccore/FW640437, (20210630), XP055819801
    [ ] - Anonymous, "WO 2005116204-A/222231: Double strand polynucleotides generating RNA i - Nucleotide - NCBI", (20110418), URL: https://www.ncbi.nlm.nih.gov/nuccore/FW815705, (20210701), XP055820216
 [A]  - CHEN YIJIE ET AL, "Highly effective inhibition of lung cancer growth and metastasis by systemic delivery of siRNA via multimodal mesoporous silica-based nanocarrier", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, (20140929), vol. 35, no. 38, doi:10.1016/J.BIOMATERIALS.2014.09.003, ISSN 0142-9612, pages 10058 - 10069, XP029074751 [A] 1-15

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2014.09.003
 [A]  - KIM WANIL; ET AL, "Obtusilactone B from Machilus Thunbergii targets barrier-to-autointegration factor to treat cancer.", MOLECULAR PHARMACOLOGY, (20130201), vol. 83, pages 367 - 376, XP055783026 [A] 1-15
 [A]  - B.H. JOSHI ET AL, "siRNA: novel therapeutics from functional genomics", BIOTECHNOLOGY AND GENETIC ENGINEERING REVIEWS, (20140102), vol. 30, no. 1, doi:10.1080/02648725.2014.921495, ISSN 0264-8725, pages 1 - 30, XP055209019 [A] 1-15

DOI:   http://dx.doi.org/10.1080/02648725.2014.921495
 [AP]  - SHEN QINGYU ET AL, "SF3B4 as an early-stage diagnostic marker and driver of hepatocellular carcinoma", BMB REPORTS, (20180228), vol. 51, no. 2, doi:10.5483/BMBRep.2018.51.2.021, pages 57 - 58, XP055818583 [AP] 1-15

DOI:   http://dx.doi.org/10.5483/BMBRep.2018.51.2.021
 [AP]  - Tsai Chia-Kuang ET AL, "Overexpression of PLOD3 promotes tumor progression and poor prognosis in gliomas INTRODUCTION", Oncotarget, (20180320), pages 15705 - 15720, URL: https://www.oncotarget.com/article/24594/pdf/, (20210628), XP055818589 [AP] 1,2,5,7-15
 [A]  - WENTAO ZHOU ET AL, "SF3B4 is decreased in pancreatic cancer and inhibits the growth and migration of cancer cells", TUMOR BIOLOGY, (20170301), pages 1 - 9, URL: https://journals.sagepub.com/doi/pdf/10.1177/1010428317695913, XP055820222 [A] 1,2,6-15
 [A]  - Qingyu Shen, "Abstract 4472: A subunit of splicing factor 3b, SF3B4, functions as driver of liver cancer via aberrant splicing activity on tumor suppressor KLF4 | Cancer Research", (20170405), URL: https://cancerres.aacrjournals.org/content/77/13_Supplement/4472, (20210701), XP055820221 [A] 1,2,6-15
International search[Y]US2014342946  (KURIAKOSE MONI ABRAHAM [IN], et al) [Y] 1-15 * See abstract; claims 1-7. *;
 [A]KR20110060209  (KOREA RES INST OF BIOSCIENCE [KR]) [A] 1-15 * See the entire document. *;
 [A]KR101150410B  (THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION) [A] 1-15 * See the entire document. *;
 [A]KR101077179B  (IN-D-UST-RY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY) [A] 1-15 * See the entire document. *
 [Y]  - IGUCHI, TOMOHIRO et al., "Increased Copy Number of the Gene Encoding SF3B4 Indicates Poor Prognosis in Hepatocellular Carcinoma", Anticancer Research, (20160000), vol. 36, no. 5, pages 2139 - 2144, XP055623564 [Y] 1-15 * See abstract; page 2141, Result section. *
by applicant   - "pharmaceutical Science", REMINGTON, U.S.P, Mack Publishing Company
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.