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Extract from the Register of European Patents

EP About this file: EP3668502

EP3668502 - MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 24.03.2023 Database last updated on 12.07.2024
Former	Examination is in progress Status updated on 14.07.2022
Former	Request for examination was made Status updated on 22.05.2020
Former	The international publication has been made Status updated on 22.02.2019
Most recent event Tooltip	24.03.2023	Application deemed to be withdrawn	published on 26.04.2023 [2023/17]
Applicant(s)	For all designated states AbbVie Inc. 1 North Waukegan Road North Chicago, IL 60064 / US
	For all designated states Abbvie Deutschland GmbH & Co. KG Mainzer Straße 81 65189 Wiesbaden / DE
	[2020/29]
Former [2020/26]	For all designated states AbbVie Inc. 1 North Waukegan Road North Chicago, IL 60064 / US
	For all designated states Abbvie Deutschland GmbH & Co. KG Mainzer Straße 81 65189 Wiesbaden / DE
	For all designated states Braje, Wilfried Mainzer Str. 81 65189 Wiesbaden / DE
	For all designated states Doherty, George 1605 Bush Court Libertyville, IL 60048 / US
	For all designated states Jantos, Katja Mainzer Str. 81 65189 Wiesbaden / DE
	For all designated states Ji, Cheng 930 Shady Grove Lane Buffalo Grove, IL 60089 / US
	For all designated states Judd, Andrew 138 Mainsail Drive Grayslake, IL 60030 / US
	For all designated states Kunzer, Aaron 903 West Berkley Drive Arlington Heights, IL 60004 / US
	For all designated states Mastracchio, Anthony 1047 Crane Boulevard Libertyville, IL 60048 / US
	For all designated states Song, Xiaohong 34037 Sulkey Drive Grayslake, IL 60030 / US
	For all designated states Souers, Andrew 156 Blueberry Road Libertyville, IL 60048 / US
	For all designated states Sullivan, Gerard 1312 Appletree Ln. Libertyville, IL 60048 / US
	For all designated states Tao, Zhi-Fu 303 Hobblebush Lane Vernon Hills, IL 60061 / US
	For all designated states Lai, Chunqiu 1103 Tamarack Lane Libertyville, IL 60048 / US
	For all designated states Kling, Andreas Mainzer Str. 81 65189 Wiesbaden / DE
	For all designated states Pohlki, Frauke Mainzer Str. 81 65189 Wiesbaden / DE
	For all designated states Teske, Jesse 617 Smith Avenue Lake Bluff, IL 60044 / US
	For all designated states Wendt, Michael 1455 Maidstone Drive Vernon Hills, IL 60061 / US
	For all designated states Brady, Patrick 413 Ashford Lane Grayslake, Illinois 60030 / US
	For all designated states Wang, Xilu 1617 Eric Lane Libertyville, IL 60048 / US
	For all designated states Penning, Thomas 321 Highview Elmhurst, IL 60126 / US
	For all designated states Michaelides, Michael 4452 W. Gavin Ln Libertyville, IL 60048 / US
Inventor(s)	01 / BRAJE, Wilfried c/o Abbvie Deutschland Gmbh & Co. KG Mainzer Str. 81 65189 Wiesbaden / DE
	02 / DOHERTY, George 1605 Bush Court Libertyville IL 60048 / US
	03 / JANTOS, Katja c/o Abbvie Deutschland Gmbh & Co. KG Mainzer Str. 81 65189 Wiesbaden / DE
	04 / JI, Cheng 930 Shady Grove Lane Buffalo Grove IL 60089 / US
	05 / JUDD, Andrew 138 Mainsail Drive Grayslake IL 60030 / US
	06 / KUNZER, Aaron 903 West Berkley Drive Arlington Heights IL 60004 / US
	07 / MASTRACCHIO, Anthony 1047 Crane Boulevard Libertyville IL 60048 / US
	08 / SONG, Xiaohong 34037 Sulkey Drive Grayslake IL 60030 / US
	09 / SOUERS, Andrew 156 Blueberry Road Libertyville IL 60048 / US
	10 / SULLIVAN, Gerard 1312 Appletree Ln Libertyville IL 60048 / US
	11 / TAO, Zhi-Fu 303 Hobblebush Lane Vernon Hills IL 60061 / US
	12 / LAI, Chunqui 1103 Tamarack Lane Libertyville IL 60048 / US
	13 / KLING, Andreas c/o Abbvie Deutschland Gmbh & Co. KG Mainzer Str. 81 Wiesbaden 65189 / DE
	14 / POHLKI, Frauke c/o Abbvie Deutschland Gmbh & Co. KG Mainzer Str. 81 Wiesbaden 65189 / DE
	15 / TESKE, Jessc 617 Smith Avenue Lake Bluff IL 60044 / US
	16 / WENDT, Michael 1455 Maidstone Drive Vernon Hills IL 60061 / US
	17 / BRADY, Patrick 413 Ashford Land Grayslake IL 60030 / US
	18 / WANG, Xilu 1617 Eric Lane Libertyville IL 60048 / US
	19 / PENNING, Thomas 321 Highview Elmhurst IL 60126 / US
	20 / MICHAELIDES, Michael 4452 W. Gavin Ln Libertyville IL 60048 / US
	[2020/32]
Former [2020/29]	01 / BRAJE, Wilfried 4452 W. Gavin Ln Libertyville IL 60048 / DE
	02 / DOHERTY, George 4452 W. Gavin Ln Libertyville IL 60048 / US
	03 / JANTOS, Katja 4452 W. Gavin Ln Libertyville IL 60048 / DE
	04 / JI, Cheng 4452 W. Gavin Ln Libertyville IL 60048 / US
	05 / JUDD, Andrew 4452 W. Gavin Ln Libertyville IL 60048 / US
	06 / KUNZER, Aaron 4452 W. Gavin Ln Libertyville IL 60048 / US
	07 / MASTRACCHIO, Anthony 4452 W. Gavin Ln Libertyville IL 60048 / US
	08 / SONG, Xiaohong 4452 W. Gavin Ln Libertyville IL 60048 / US
	09 / SOUERS, Andrew 4452 W. Gavin Ln Libertyville IL 60048 / US
	10 / SULLIVAN, Gerard 4452 W. Gavin Ln Libertyville IL 60048 / US
	11 / TAO, Zhi-Fu 4452 W. Gavin Ln Libertyville IL 60048 / US
	12 / LAI, Chunqiu 4452 W. Gavin Ln Libertyville IL 60048 / US
	13 / KLING, Andreas 4452 W. Gavin Ln Libertyville IL 60048 / DE
	14 / POHLKI, Frauke 4452 W. Gavin Ln Libertyville IL 60048 / DE
	15 / TESKE, Jessc 4452 W. Gavin Ln Libertyville IL 60048 / US
	16 / WENDT, Michael 4452 W. Gavin Ln Libertyville IL 60048 / US
	17 / BRADY, Patrick 4452 W. Gavin Ln Libertyville IL 60048 / US
	18 / WANG, Xilu 4452 W. Gavin Ln Libertyville IL 60048 / US
	19 / PENNING, Thomas 4452 W. Gavin Ln Libertyville IL 60048 / US
	20 / MICHAELIDES, Michael 4452 W. Gavin Ln Libertyville IL 60048 / US
Former [2020/26]	01 / BRAJE, Wilfried 4452 W. Gavin Ln Libertyville IL 60048 / DE
	02 / DOHERTY, George 4452 W. Gavin Ln Libertyville IL 60048 / US
	03 / JANTOS, Katja 4452 W. Gavin Ln Libertyville IL 60048 / DE
	04 / JI, Cheng 4452 W. Gavin Ln Libertyville IL 60048 / US
	05 / JUDD, Andrew 4452 W. Gavin Ln Libertyville IL 60048 / US
	06 / KUNZER, Aaron 4452 W. Gavin Ln Libertyville IL 60048 / US
	07 / MASTRACCHIO, Anthony 4452 W. Gavin Ln Libertyville IL 60048 / US
	08 / SONG, Xiaohong 4452 W. Gavin Ln Libertyville IL 60048 / US
	09 / SOUERS, Andrew 4452 W. Gavin Ln Libertyville IL 60048 / US
	10 / SULLIVAN, Gerard 4452 W. Gavin Ln Libertyville IL 60048 / US
	11 / TAO, Zhi-Fu 4452 W. Gavin Ln Libertyville IL 60048 / US
	12 / LAI, Chunqui 4452 W. Gavin Ln Libertyville IL 60048 / US
	13 / KLING, Andreas 4452 W. Gavin Ln Libertyville IL 60048 / DE
	14 / POHLKI, Frauke 4452 W. Gavin Ln Libertyville IL 60048 / DE
	15 / TESKE, Jessc 4452 W. Gavin Ln Libertyville IL 60048 / US
	16 / WENDT, Michael 4452 W. Gavin Ln Libertyville IL 60048 / US
	17 / BRADY, Patrick 4452 W. Gavin Ln Libertyville IL 60048 / US
	18 / WANG, Xilu 4452 W. Gavin Ln Libertyville IL 60048 / US
	19 / PENNING, Thomas 4452 W. Gavin Ln Libertyville IL 60048 / US
	20 / MICHAELIDES, Michael 4452 W. Gavin Ln Libertyville IL 60048 / US
Representative(s)	Schlich, George, et al Schlich 9 St Catherine's Road Littlehampton, West Sussex BN17 5HS / GB
	[2020/26]
Application number, filing date	18845598.4	15.08.2018
	[2020/26]
	WO2018US00196
Priority number, date	US201762545872P	15.08.2017 Original published format: US 201762545872 P
	US201762555477P	07.09.2017 Original published format: US 201762555477 P
	US201862692667P	30.06.2018 Original published format: US 201862692667 P
	[2020/26]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2019035927
	Date:	21.02.2019
	Language:	EN
	[2019/08]
	Type:	A1 Application with search report
	No.:	EP3668502
	Date:	24.06.2020
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 21.02.2019 takes the place of the publication of the European patent application.
	[2020/26]
Search report(s)	International search report - published on:	US	21.02.2019
	(Supplementary) European search report - dispatched on:	EP	16.12.2020
Classification	IPC:	C07D515/22, A61K31/395, A61P35/00	[2021/02]
	CPC:	C07D495/16 (EP,US); A61K31/519 (EP); A61K45/06 (EP); A61P35/00 (EP,US); C07D519/00 (EP,US)
	Former IPC [2020/26]	A61K31/395, A61P35/00, C07D515/22
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2020/26]
Extension states	BA	28.02.2020
	ME	28.02.2020
Title	German:	MAKROCYCLISCHE MCL-1-INHIBITOREN UND VERFAHREN ZUR VERWENDUNG	[2020/26]
	English:	MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE	[2020/26]
	French:	INHIBITEURS DE MCL-1 MACROCYCLIQUE ET PROCÉDÉS D'UTILISATION	[2020/26]
Entry into regional phase	28.02.2020	National basic fee paid
	28.02.2020	Search fee paid
	28.02.2020	Designation fee(s) paid
	28.02.2020	Examination fee paid
Examination procedure	28.02.2020	Examination requested [2020/26]
	06.07.2021	Amendment by applicant (claims and/or description)
	13.07.2022	Despatch of a communication from the examining division (Time limit: M04)
	24.11.2022	Application deemed to be withdrawn, date of legal effect [2023/17]
	15.12.2022	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2023/17]
Fees paid	Renewal fee
	28.02.2020	Renewal fee patent year 03
	09.08.2021	Renewal fee patent year 04
	Penalty fee
	Additional fee for renewal fee
	31.08.2022	05 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[A]WO2012156756 (CT NAC INVESTIGACIONES ONCOLOGICAS CNIO [ES], et al);
		[A]WO2017125224 (SERVIER LAB [FR], et al);
		[E]WO2019035914 (ABBVIE INC [US], et al);
		[E]WO2019035911 (ABBVIE INC [US], et al)
	International search	[A]US2009275533 (HSIEH HSING-PANG [TW], et al);
		[A]US2015175623 (KOTSCHY ANDRÁS [HU], et al);
		[A]WO2015097123 (SERVIER LAB [FR], et al);

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

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