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Extract from the Register of European Patents

EP About this file: EP3681526

EP3681526 - PEPTIDE INHIBITORS OF INSULIN-DEGRADING ENZYME [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  05.08.2022
Database last updated on 20.07.2024
FormerRequest for examination was made
Status updated on  19.06.2020
FormerThe international publication has been made
Status updated on  22.03.2019
Most recent event   Tooltip05.08.2022Application deemed to be withdrawnpublished on 07.09.2022  [2022/36]
Applicant(s)For all designated states
The Regents of the University of California
1111 Franklin Street 12th Floor
Oakland, CA 94607-5200 / US
[2020/30]
Inventor(s)01 / LEISSRING, Malcolm A.
1061 South Coast Highway
Laguna Beach, California 92651 / US
 [2020/30]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[2020/30]
Application number, filing date18857213.511.09.2018
[2020/30]
WO2018US50508
Priority number, dateUS201762557662P12.09.2017         Original published format: US 201762557662 P
[2020/30]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019055431
Date:21.03.2019
Language:EN
[2019/12]
Type: A1 Application with search report 
No.:EP3681526
Date:22.07.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 21.03.2019 takes the place of the publication of the European patent application.
[2020/30]
Search report(s)International search report - published on:US21.03.2019
(Supplementary) European search report - dispatched on:EP06.09.2021
ClassificationIPC:C07K7/08, C07K7/06, A61K38/08, A61K38/05
[2021/27]
CPC:
C07K7/08 (EP,US); C07K7/64 (US); A61K38/08 (US);
A61K38/10 (US); A61K38/12 (US); A61K38/55 (US);
A61K45/06 (US); A61K8/64 (EP,US); A61P17/02 (EP,US);
A61P3/10 (US); A61Q19/00 (EP); A61Q19/08 (US);
C07K14/81 (US); C07K7/06 (EP,US); C12N9/6489 (EP);
C12Y304/24056 (EP); A61K2800/91 (EP); A61K2800/92 (EP);
A61K38/00 (EP,US) (-)
Former IPC [2020/30]A61K38/08, A61K38/05, C07K7/06
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/30]
TitleGerman:PEPTID-INHIBITOREN DES INSULINABBAUENDEN ENZYMS[2020/30]
English:PEPTIDE INHIBITORS OF INSULIN-DEGRADING ENZYME[2020/30]
French:INHIBITEURS PEPTIDIQUES DE L'ENZYME DE DÉGRADATION DE L'INSULINE[2020/30]
Entry into regional phase20.03.2020National basic fee paid 
20.03.2020Search fee paid 
20.03.2020Designation fee(s) paid 
20.03.2020Examination fee paid 
Examination procedure20.03.2020Examination requested  [2020/30]
30.10.2020Amendment by applicant (claims and/or description)
01.04.2022Application deemed to be withdrawn, date of legal effect  [2022/36]
04.05.2022Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2022/36]
Fees paidRenewal fee
28.09.2020Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
30.09.202104   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]  - MAIANTI J P ET AL, "Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones", NATURE, (20140521), vol. 511, no. 7507, doi:10.1038/nature13297, pages 94 - 98, XP055565653 [A] 1-15 * the whole document, in particular abstract; figure 1b;; compound 6bK *

DOI:   http://dx.doi.org/10.1038/nature13297
 [A]  - LEISSRING M A ET AL, "Designed Inhibitors of Insulin-Degrading Enzyme Regulate the Catabolism and Activity of Insulin", PLOS ONE, vol. 5, no. 5, doi:10.1371/journal.pone.0010504, (20100501), page e10504, URL: https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pone.0010504/1/pone.0010504.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa@plos-prod.iam.gserviceaccount.com/20210525/auto/storage/goog4_request&X-Goog-Date=20210525T094124Z&X-Goog-Expires=86400&X-Goog-SignedHeaders=h, XP055807011 [A] 1-15 * the whole document, in particular abstract; figures 1, 2 *

DOI:   http://dx.doi.org/10.1371/journal.pone.0010504
 [XP]  - SUIRE C N ET AL, "Peptidic inhibitors of insulin-degrading enzyme with potential for dermatological applications discovered via phage display", PLOS ONE, (20180215), vol. 13, no. 2, doi:10.1371/journal.pone.0193101, page e0193101, XP055475376 [XP] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1371/journal.pone.0193101
 [T]  - LEISSRING M A ET AL, "International Journal of Molecular Sciences Targeting Insulin-Degrading Enzyme in Insulin Clearance", INT. J. MOL. SCI, vol. 22, (20210101), page 2235, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956289/pdf/ijms-22-02235.pdf, XP055807025 [T] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.3390/ijms22052235
International search[A]US2002168711  (ROSEN CRAIG A [US], et al) [A] 1, 2, 3/1-2 * ; SEQ ID NO: 838 *;
 [A]US2004158891  (THOMPSON JOHN E [CA], et al) [A] 1, 2, 3/1-2* ; paragraph [0015]; SEQ ID NO: 19 *;
 [A]US2012028894  (FRENKEL DAN [IL], et al) [A] 1, 2, 3/1-2 * ; abstract; paragraphs [0012], [0018]-[0020], [0064], [0070] *;
 [A]WO2016172631  (HARVARD COLLEGE [US]) [A] 1, 2, 3/1-2 * ; abstract; paragraphs [0006], [0008], [0039]; SEQ ID NO: 4 *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.