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Extract from the Register of European Patents

EP About this file: EP3693377

EP3693377 - METHOD FOR PRODUCING PEPTIDE COMPOUND [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  10.07.2020
Database last updated on 12.07.2024
FormerThe international publication has been made
Status updated on  13.04.2019
Most recent event   Tooltip27.10.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Nissan Chemical Corporation
5-1, Nihonbashi 2-chome
Chuo-ku
Tokyo 103-6119 / JP
For all designated states
PeptiDream Inc.
3-25-23, Tonomachi
Kawasaki-ku
Kawasaki-shi, Kanagawa 210-0821 / JP
[2020/33]
Inventor(s)01 / NAGAYA, Akihiro
c/o Nissan Chemical Corporation
Chemical Research Laboratories
10-1
Tsuboi-Nishi 2-chome
Funabashi-shi Chiba 274-8507 / JP
02 / HANDA, Michiharu
c/o Nissan Chemical Corporation
Chemical Research Laboratories
10-1
Tsuboi-Nishi 2-chome
Funabashi-shi Chiba 274-8507 / JP
03 / YASUDA, Naohiko
c/o Nissan Chemical Corporation
Chemical Research Laboratories
10-1
Tsuboi-Nishi 2-chome
Funabashi-shi Chiba 274-8507 / JP
04 / YOSHINO, Madoka
c/o Nissan Chemical Corporation
Chemical Research Laboratories
10-1
Tsuboi-Nishi 2-chome
Funabashi-shi Chiba 274-8507 / JP
05 / KOBAYASHI, Yutaka
c/o PeptiDream Inc.
3-25-23
Tonomachi
Kawasaki-ku
Kawasaki-shi Kanagawa 210-0821 / JP
06 / MASUYA, Keiichi
c/o PeptiDream Inc.
3-25-23
Tonomachi
Kawasaki-ku
Kawasaki-shi Kanagawa 210-0821 / JP
 [2020/33]
Representative(s)dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[2020/33]
Application number, filing date18864861.203.10.2018
[2020/33]
WO2018JP37032
Priority number, dateJP2017019330903.10.2017         Original published format: JP 2017193309
JP2018013457517.07.2018         Original published format: JP 2018134575
JP2018018050126.09.2018         Original published format: JP 2018180501
[2020/33]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019069978
Date:11.04.2019
Language:JA
[2019/15]
Type: A1 Application with search report 
No.:EP3693377
Date:12.08.2020
Language:EN
[2020/33]
Search report(s)International search report - published on:JP11.04.2019
(Supplementary) European search report - dispatched on:EP02.06.2021
ClassificationIPC:C07K1/06
[2020/33]
CPC:
C07K1/02 (EP); C07K1/063 (US); C07F7/1804 (US);
C07K1/062 (US); C07K5/0812 (EP,US); C07K5/1016 (EP,US);
C07K7/06 (US); Y02P20/55 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/33]
TitleGerman:VERFAHREN ZUR HERSTELLUNG EINER PEPTIDVERBINDUNG[2020/33]
English:METHOD FOR PRODUCING PEPTIDE COMPOUND[2020/33]
French:PROCÉDÉ DE PRODUCTION DE COMPOSÉ PEPTIDIQUE[2020/33]
Entry into regional phase17.04.2020Translation filed 
17.04.2020National basic fee paid 
17.04.2020Search fee paid 
17.04.2020Designation fee(s) paid 
17.04.2020Examination fee paid 
Examination procedure17.04.2020Examination requested  [2020/33]
27.12.2021Amendment by applicant (claims and/or description)
Fees paidRenewal fee
28.10.2020Renewal fee patent year 03
28.10.2021Renewal fee patent year 04
27.10.2022Renewal fee patent year 05
26.10.2023Renewal fee patent year 06
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[AD]WO9305065  (PORTON DEV LTD [GB]) [AD] 1-15 * page 10 - page 11 *;
 [A]WO2012087888  (ONYX PHARMA INC [US], et al) [A] 1-15 * compound 18 *;
 [A]  - BORSUK K ET AL, "Application of substituted 2-(trimethylsilyl)ethyl esters to suppress diketopiperazine formation", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM , NL, vol. 45, no. 18, ISSN 0040-4039, (20040426), pages 3585 - 3588, (20040409), XP027092766 [A] 1-15 * abstract * * Scheme 3 *
 [A]  - MARCO BRANDSTÄTTER ET AL, "Synthesis of 2-Oxazolines by in Situ Desilylation and Cyclodehydration of [beta]-Hydroxyamides", JOURNAL OF ORGANIC CHEMISTRY, Washington, (20141218), vol. 80, no. 1, doi:10.1021/jo5016695, ISSN 0022-3263, pages 40 - 51, XP055590110 [A] 1-15 * Scheme 3 *

DOI:   http://dx.doi.org/10.1021/jo5016695
 [A]  - MARTIN STRACK ET AL, "Silyl-Based Alkyne-Modifying Linker for the Preparation of C-Terminal Acetylene-Derivatized Protected Peptides", JOURNAL OF ORGANIC CHEMISTRY, Washington, (20121101), vol. 77, no. 22, doi:10.1021/jo302305d, ISSN 0022-3263, pages 9954 - 9958, XP055590113 [A] 1-15 * Scheme 2 *

DOI:   http://dx.doi.org/10.1021/jo302305d
International search[A]JPH04502908  [A] 1-27 * & *;
 [Y]WO9305065  (PORTON DEV LTD [GB]) [Y] 1-27 * , *;
 [Y]JP2014513663  [Y] 1-27 * , *;
 [Y]  - BORSUK KATARZYNA et al., "Application of substituted 2-(trimethylsilyl)ethyl esters to suppress diketopiperazine formation", Tetrahedron Letters, (20040000), vol. 45, no. 18, doi:10.1016/j.tetlet.2004.03.054, ISSN 0040-4039, pages 3585 - 3588, XP027092766 [Y] 1-27 * , see Abstract, right-hand column of p.3585, Scheme 3 *
 [Y]  - BRANDSTATTER MARCO et al., "Synthesis of 2-Oxazolines by in Situ Desilylation and Cyclodehydration of beta-Hydroxyamides", J. Org. Chem., (20150000), vol. 80, no. 1, pages 40 - 51, XP055590110 [Y] 1-27 * , see Scheme 3 *

DOI:   http://dx.doi.org/10.1021/jo5016695
 [A]  - STRACK MARTIN et al., "Silyl-Based Alkyne-Modifying Linker for the Preparation of C-Terminal Acetylene-Derivatized Protected Peptides", J. Org. Chem., (20120000), vol. 77, no. 22, doi:10.1021/jo302305d, ISSN 0022-3263, pages 9954 - 9958, XP055590113 [A] 1-27

DOI:   http://dx.doi.org/10.1021/jo302305d
 [A]  - ISIDRO-LIOBET ALBERT et al., "Amino Acid-Protecting Groups", Chem. Rev., (20090000), vol. 109, doi:doi:10.1021/cr800323s, pages 2455 - 2504, XP055559012 [A] 1-27

DOI:   http://dx.doi.org/10.1021/cr800323s
by applicantJPH04502908
 WO9305065
    - Science of Synthesis, (20020000), vol. 4, pages 293 - 303
    - The second series of Pharmaceutical Research and Development, (19910000), vol. 14, pages 3 - 10
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