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Extract from the Register of European Patents

EP About this file: EP3524600

EP3524600 - PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.09.2022
Database last updated on 09.04.2026
FormerThe patent has been granted
Status updated on  21.10.2021
FormerGrant of patent is intended
Status updated on  22.07.2021
FormerExamination is in progress
Status updated on  02.03.2020
FormerRequest for examination was made
Status updated on  13.12.2019
FormerThe application has been published
Status updated on  12.07.2019
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR		published on 17.07.2024  [2024/29]
Applicant(s)For all designated states
Sanofi
54, rue La Boétie
75008 Paris / FR
[2019/33]
Inventor(s)01 / BOUABOULA, Monsif
c/o SANOFI - Patent Department
55 Corporate Drive
55A-505A
BRIDGEWATER, NJ 8807 / US
02 / BROLLO, Maurice
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
03 / CERTAL, Victor
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
04 / EL-AHMAD, Youssef
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
05 / FILOCHE-ROMME, Bruno
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
06 / HALLEY, Frank
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
07 / MCCORT, Gary
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
08 / SCHIO, Laurent
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
09 / TABART, Michel
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
10 / TERRIER, Corinne
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
11 / THOMPSON, Fabienne
c/o SANOFI Patent Department
54, rue la Boetie
75008 PARIS / FR
 [2019/33]
Representative(s)Ipsilon
11 rue Saint-Georges
75009 Paris / FR
[N/P]
Former [2019/33]Nony
11 rue Saint-Georges
75009 Paris / FR
Application number, filing date19164243.814.02.2017
[2019/33]
Priority number, dateEP2016030517415.02.2016         Original published format: EP 16305174
[2019/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3524600
Date:14.08.2019
Language:EN
[2019/33]
Type: B1 Patent specification 
No.:EP3524600
Date:17.11.2021
Language:EN
[2021/46]
Search report(s)(Supplementary) European search report - dispatched on:EP03.06.2019
ClassificationIPC:C07D403/12, C07D401/12, C07D405/12, C07D413/12, C07D417/12, C07D471/04, C07D207/12, A61K31/40, A61K31/4025, A61P35/00, C07F5/02
[2019/33]
CPC:
C07D207/12 (EP,CN,EA,IL,KR,US); A61K31/4025 (EA); A61K31/4015 (KR);
A61K31/4439 (KR); A61K31/506 (KR); A61P13/08 (EA,IL);
A61P15/00 (EA,IL); A61P15/08 (EA,IL); A61P19/10 (EA,IL);
A61P29/00 (EA,IL); A61P35/00 (CN,EA,IL,KR); A61P35/04 (EA,IL);
A61P43/00 (EA,IL); A61P5/32 (EA,IL); C07D209/08 (CN);
C07D401/12 (EP,CN,EA,IL,KR,US); C07D403/12 (EP,CN,EA,IL,KR,US); C07D405/12 (EP,CN,EA,IL,KR,US);
C07D413/12 (EP,EA,IL,US); C07D417/12 (EP,EA,IL,KR,US); C07D471/04 (EP,EA,IL,KR,US);
C07F5/025 (EP,CN,EA,IL,US); C07F5/027 (KR); C07F7/0812 (EA,IL,US);
C07F9/572 (CN); C07B2200/07 (CN) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/03]
Former [2019/33]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
Validation statesMA21.03.2019
TitleGerman:VERFAHREN UND ZWISCHENPRODUKTE ZUR HERSTELLUNG VON NEUARTIGEN SUBSTITUIERTEN 6,7-DIHYDRO-5H-BENZO[7]ANNULEN-VERBINDUNGEN[2019/33]
English:PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS[2019/33]
French:PROCÉDÉS ET INTERMÉDIAIRES POUR LA PRÉPARATION DE NOUVEAUX COMPOSÉS SUBSTITUÉS DE 6,7-DIHYDRO-5H-BENZO[7]ANNULÈNE[2019/33]
Examination procedure06.12.2019Amendment by applicant (claims and/or description)
06.12.2019Examination requested  [2020/03]
06.12.2019Date on which the examining division has become responsible
05.03.2020Despatch of a communication from the examining division (Time limit: M04)
25.06.2020Reply to a communication from the examining division
26.08.2020Despatch of a communication from the examining division (Time limit: M02)
05.10.2020Reply to a communication from the examining division
25.11.2020Despatch of a communication from the examining division (Time limit: M04)
22.02.2021Reply to a communication from the examining division
23.07.2021Communication of intention to grant the patent
12.10.2021Fee for grant paid
12.10.2021Fee for publishing/printing paid
12.10.2021Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP17705842.7  / EP3416962
Opposition(s)18.08.2022No opposition filed within time limit [2022/43]
Fees paidRenewal fee
21.03.2019Renewal fee patent year 03
13.02.2020Renewal fee patent year 04
12.02.2021Renewal fee patent year 05
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAL17.11.2021
EE17.11.2021
FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
MK17.11.2021
PL17.11.2021
RO17.11.2021
RS17.11.2021
SI17.11.2021
SK17.11.2021
SM17.11.2021
TR17.11.2021
LU14.02.2022
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
[2024/29]
Former [2024/23]AL17.11.2021
EE17.11.2021
FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
MK17.11.2021
PL17.11.2021
RO17.11.2021
RS17.11.2021
SI17.11.2021
SK17.11.2021
SM17.11.2021
LU14.02.2022
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2023/01]AL17.11.2021
EE17.11.2021
FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RO17.11.2021
RS17.11.2021
SI17.11.2021
SK17.11.2021
SM17.11.2021
LU14.02.2022
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2022/49]AL17.11.2021
EE17.11.2021
FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RO17.11.2021
RS17.11.2021
SK17.11.2021
SM17.11.2021
LU14.02.2022
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2022/47]EE17.11.2021
FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RO17.11.2021
RS17.11.2021
SK17.11.2021
SM17.11.2021
LU14.02.2022
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2022/35]EE17.11.2021
FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RO17.11.2021
RS17.11.2021
SK17.11.2021
SM17.11.2021
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2022/34]EE17.11.2021
FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RO17.11.2021
RS17.11.2021
SM17.11.2021
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2022/33]FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RS17.11.2021
SM17.11.2021
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2022/24]FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RS17.11.2021
BG17.02.2022
GR18.02.2022
IS17.03.2022
PT17.03.2022
Former [2022/23]FI17.11.2021
HR17.11.2021
LT17.11.2021
LV17.11.2021
PL17.11.2021
RS17.11.2021
BG17.02.2022
PT17.03.2022
Former [2022/22]FI17.11.2021
LT17.11.2021
RS17.11.2021
BG17.02.2022
Former [2022/21]RS17.11.2021
BG17.02.2022
Former [2022/19]BG17.02.2022
Documents cited:Search[A] WO2013097773  (CENTAURUS BIOPHARMA CO LTD et al.)
 [A]   ANSTEAD G M ET AL: "2,3-Diarylindenes and 2,3-diarylindenones: synthesis, molecular structure, photochemistry, oestrogen receptor binding affinity, and comparisons with related triarylethylenes", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 31, no. 7, July 1988 (1988-07-01), pages 1316 - 1326, XP002121530, ISSN: 0022-2623, DOI: 10.1021/JM00402A011

DOI:   http://dx.doi.org/10.1021/jm00402a011
 [A]   MCCAGUE R ET AL: "Nonisomerisable analogues of (Z)- and (E)-4-hydroxytamoxifen. Synthesis and endocrinological properties of substituted diphenylbenzocycloheptenes", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 31, no. 7, July 1988 (1988-07-01), pages 1285 - 1290, XP002121529, ISSN: 0022-2623, DOI: 10.1021/JM00402A005

DOI:   http://dx.doi.org/10.1021/jm00402a005
by applicant  G.M. ANSTEAD ET AL.: "2,3-diarylindenes and 2,3-diarylindenones as binders of estrogen receptors", JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, no. 7, 1988, pages 1316 - 1326
   R. MCCAGUE ET AL.: "analogues of (Z)- and (E)-4-hydroxytamoxifen and have tested their binding affinities to estrogen receptors", JOURNAL OF MEDICINAL CHEMISTRY, vol. 31, no. 7, 1998, pages 1285 - 1290
   T.W. GREENE; P. G. M. WUTS: "Protective Groups in Organic Chemistry", 2006, JOHN WILEY AND SONS
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.