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Extract from the Register of European Patents

EP About this file: EP3590956

EP3590956 - SUPPRESSION OF NEUROENDOCRINE DISEASES [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  06.12.2019
Database last updated on 12.11.2024
Most recent event   Tooltip13.05.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Ipsen Bioinnovation Limited
102 Park Drive
Milton Park
Abingdon, Oxfordshire OX14 4RY / GB
[2020/02]
Inventor(s)01 / JOHNSTONE, Stephen
c/o IPSEN BIOINNOVATION LIMITED
102 Park Drive
Milton Park
Abingdon, Oxfordshire OX14 4RY / GB
02 / MARKS, Philip
c/o IPSEN BIOINNOVATION LIMITED
102 Park Drive
Milton Park
Abingdon, Oxfordshire OX14 4RY / GB
03 / FOSTER, Keith
c/o IPSEN BIOINNOVATION LIMITED
102 Park Drive
Milton Park
Abingdon, Oxfordshire OX14 4RY / GB
 [2020/02]
Representative(s)Hobson, David James, et al
Mathys & Squire The Shard
32 London Bridge Street
London SE1 9SG / GB
[N/P]
Former [2020/02]Hobson, David James, et al
Mathys & Squire LLP The Shard
32 London Bridge Street
London SE1 9SG / GB
Application number, filing date19175007.411.06.2009
[2020/02]
Priority number, dateGB2008001078512.06.2008         Original published format: GB 0810785
GB2008001078212.06.2008         Original published format: GB 0810782
GB2008002088414.11.2008         Original published format: GB 0820884
GB2008002096517.11.2008         Original published format: GB 0820965
[2020/02]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3590956
Date:08.01.2020
Language:EN
[2020/02]
Search report(s)(Supplementary) European search report - dispatched on:EP18.11.2019
ClassificationIPC:C07K14/195, A61P35/00, C12N9/52, A61K38/48, C07K1/00
[2020/02]
CPC:
C12N9/6489 (EP,CN,US); C07K14/60 (KR); A61K38/16 (KR);
A61K38/22 (KR); A61K38/4893 (EP,US); A61K47/6415 (EP,US);
A61P1/00 (EP); A61P1/12 (EP); A61P1/18 (EP);
A61P13/12 (EP); A61P17/00 (EP); A61P25/00 (EP);
A61P3/00 (EP); A61P3/08 (EP); A61P35/00 (EP);
A61P35/04 (EP); A61P43/00 (EP); A61P5/00 (EP);
A61P5/02 (EP); A61P5/06 (EP); A61P7/00 (EP);
A61P9/12 (EP); A61K38/00 (CN); C07K2319/035 (EP,CN,US);
C07K2319/06 (EP,CN,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2020/02]
Extension statesAL05.06.2019
BA05.06.2019
RS05.06.2019
TitleGerman:UNTERDRÜCKUNG VON NEUROENDOKRINEN ERKRANKUNGEN[2020/02]
English:SUPPRESSION OF NEUROENDOCRINE DISEASES[2020/02]
French:SUPPRESSION DE MALADIES NEUROENDOCRINES[2020/02]
Examination procedure05.06.2019Examination requested  [2020/02]
08.07.2020Amendment by applicant (claims and/or description)
Parent application(s)   TooltipEP09762018.1  / EP2310028
EP13179177.4  / EP2719392
Fees paidRenewal fee
05.06.2019Renewal fee patent year 03
05.06.2019Renewal fee patent year 04
05.06.2019Renewal fee patent year 05
05.06.2019Renewal fee patent year 06
05.06.2019Renewal fee patent year 07
05.06.2019Renewal fee patent year 08
05.06.2019Renewal fee patent year 09
05.06.2019Renewal fee patent year 10
05.06.2019Renewal fee patent year 11
31.03.2020Renewal fee patent year 12
14.06.2021Renewal fee patent year 13
31.03.2022Renewal fee patent year 14
31.03.2023Renewal fee patent year 15
13.05.2024Renewal fee patent year 16
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[IY]WO0121213  (MICROBIOLOGICAL RES AUTHORITY [GB]) [I] 1-11 * claims 1-39 * [Y] 1-11;
 [IY]US2003180289  (FOSTER KEITH ALAN [GB], et al) [I] 1-11 * claims 1-6 * [Y] 1-11;
 [Y]US2005031648  (BRIN MITCHELL F [US], et al) [Y] 1-11 * claims 12,28,26,33,40,52 *;
 [Y]WO2006025976  (ALLERGAN INC [US], et al) [Y] 1-11 * page 55, line 24 - line 26; claim 1 * * page 61, line 23 - line 25 * * page 70, line 24 - line 27 *;
 [IY]WO2006059113  (HEALTH PROT AGENCY [GB], et al) [I] 12,13 * claims 1-23 * [Y] 1-11;
 [I]WO2006059093  (HEALTH PROT AGENCY [GB], et al) [I] 12,13 * page 21, line 2; figures 1,2; claims 1,20 *;
 [Y]WO2006099590  (ALLERGAN INC [US], et al) [Y] 1-11 * paragraph [0004] - paragraph [0006] * * paragraph [0129] *;
 [I]US2008032931  (STEWARD LANCE E [US], et al) [I] 12,13 * claims 1,47 *;
 [L]EP2310028  (SYNTAXIN LTD [GB]) [L] * the whole document *;
 [L]EP2310029  (SYNTAXIN LTD [GB]) [L] 1-13* the whole document *;
 [L]EP2719392  (SYNTAXIN LTD [GB]) [L] 1-13 * the whole document *;
 [Y]  - CHADDOCK J A ET AL, "Clostridial neurotoxins: structure-function led design of new therapeutics", CELLULAR AND MOLECULAR LIFE SCIENCES, BIRKHÄUSER-VERLAG, BA, (20060301), vol. 63, no. 5, doi:10.1007/S00018-005-5505-5, ISSN 1420-9071, pages 540 - 551, XP019201042 [Y] 1-11 * page 546, column 2 *

DOI:   http://dx.doi.org/10.1007/s00018-005-5505-5
by applicantUS4133782
 US4146612
 US4190648
 US4190575
 US4211693
 US4235886
 US4238481
 US4261885
 EP0030920
 US4282143
 US4291022
 US4310518
 US4316890
 US4328214
 US4360516
 US4369179
 FR2522655
 US4522813
 EP0171477
 US4585755
 US4603120
 US4650787
 US4659693
 US4684620
 US4725577
 EP0257742
 WO8802756
 WO8902897
 US4853371
 EP0329295
 US4871717
 US4904642
 EP0363589
 WO9003980
 EP0389180
 EP0395417
 WO9012811
 WO9102746
 WO9105563
 WO9116923
 WO9117181
 WO9118016
 US5084555
 WO9206204
 WO9213883
 EP0505680
 WO9220363
 WO9222322
 US5223409
 WO9315766
 US5240561
 WO9411397
 WO9411396
 WO9421300
 US5506339
 WO9616707
 WO9622782
 US5550212
 US5552520
 EP0737691
 WO9632126
 WO9633273
 WO9633729
 WO9701579
 WO9807864
 WO9808529
 WO9808528
 US5942489
 WO9956769
 WO9958571
 WO0004926
 WO0006185
 WO0010598
 US6057422
 WO0061192
 WO0062814
 WO0075186
 WO0121213
 WO2006059093
 US2007166332
 WO2007104567
 WO2008008803
 WO2008008805
    - NAGY et al., PNAS, (19980000), vol. 95, pages 1794 - 99
    - "In Receptor biochemistry, A Practical Approach", HULME, E.C., Receptor-binding studies, a brief outline, Oxford University Press, (19900000), pages 303 - 311
    - VAN BINST, G. et al., Peptide Research, (19920913), vol. 5, page 8
    - HORVATH, A. et al., "Conformations of Somatostatin Analogs Having Antitumor Activity", 22nd European peptide Symposium
    - ZACHARY et al., Proc. Nat. Aca. Sci., (19850000), vol. 82, page 7616
    - "UCLA Symposium on Mol. and Cell. Biol. New Series", HEIMBROOK et al., Synthetic Peptides: Approaches to Biological Problems, vol. 86
    - HEINZ-ERIAN E, Am. J. Physiol., (19860000), page G439
    - MARTINEZ et al., J. Med. Chem., (19850000), vol. 28, page 1874
    - GARGOSKY et al., Biochem. J., (19870000), vol. 247, page 427
    - DUBREUIL et al., Drug Design and Delivery, Harwood Academic Publishers, (19870000), vol. 2, page 49
    - HEIKKILA et al., J. Biol. Chem., (19870000), vol. 262, page 16456
    - CARANIKAS et al., J. Med. Chem., (19820000), vol. 25, page 1313
    - SAEED et al., Peptides, (19890000), vol. 10, page 597
    - ROSELL et al., Trends in Pharmacological Sciences, (19820000), vol. 3, page 211
    - LUNDBERG et al., Proc. Nat. Aca. Sci., (19830000), vol. 80, page 1120
    - ENGBERG et al., Nature, (19840000), vol. 293, page 222
    - MIZRAHI et al., Euro. J. Pharma., (19820000), vol. 82, page 101
    - LEANDER et al., Nature, (19810000), vol. 294, page 467
    - WOLL et al., Biochem. Biophys. Res. Comm., (19880000), vol. 155, page 359
    - RIVIER et al., Biochem., (19780000), vol. 17, page 1766
    - CUTTITTA et al., Cancer Surveys, (19850000), vol. 4, page 707
    - AUMELAS et al., Int. J. Peptide Res., (19870000), vol. 30, page 596
    - SHONE et al., Eur. J. Biochem., (19850000), vol. 151, pages 75 - 82
    - RUMMEL et al., Molecular Microbiol., (20040000), vol. 51, pages 631 - 634
    - UMLAND TC, Nat. Struct. Biol., (19970000), vol. 4, pages 788 - 792
    - HERREROS J, Biochem. J., (20000000), vol. 347, pages 199 - 204
    - HALPERN J, J. Biol. Chem., (19930000), vol. 15, pages 11188 - 11192
    - RUMMEL A, PNAS, (20070000), vol. 104, pages 359 - 364
    - LACEY DB, Nat. Struct. Biol., (19980000), vol. 5, pages 898 - 902
    - KNAPP, Am. Cryst. Assoc. Abstract Papers, (19980000), vol. 25, page 90
    - SWAMINATHANESWARAMOORTHY, Nat. Struct. Biol., (20000000), vol. 7, pages 1751 - 1759
    - RUMMEL A, Mol. Microbiol., (20040000), vol. 51, no. 3, pages 631 - 643
    - POHLNER, J. et al., Nature, (19870000), vol. 325, pages 458 - 462
    - SHONE C., Eur. J. Biochem, (19870000), vol. 167, no. 1, pages 175 - 180
    - BLAUSTEIN, FEBS Letts, (19870000), vol. 226, no. 1, pages 115 - 120
    - "Membrane Fusion Techniques", Methods in Enzymology, Academic Press, (19930000), page 220,221
    - O'KEEFE et al., Proc. Natl. Acad. Sci. USA, (19920000), vol. 89, pages 6202 - 6206
    - SILVERMAN et al., J. Biol. Chem., (19930000), vol. 269, pages 22524 - 22532
    - LONDON, E., Biochem. Biophys. Acta., (19920000), vol. 1112, pages 25 - 51
    - PRIOR et al., Biochemistry, (19920000), vol. 31, pages 3555 - 3559
    - BLANKE et al., Proc. Natl. Acad. Sci. USA, (19960000), vol. 93, pages 8437 - 8442
    - PLANK et al., J. Biol. Chem., (19940000), vol. 269, pages 12918 - 12924
    - WAGNER et al., PNAS, (19920000), vol. 89, pages 7934 - 7938
    - MURATA et al., Biochem., (19920000), vol. 31, pages 1986 - 1992
    - JULIE D. THOMPSON et al., "CLUSTAL W: Improving the Sensitivity of Progressive Multiple Sequence Alignment Through Sequence Weighting, Position- Specific Gap Penalties and Weight Matrix Choice", Nucleic Acids Research, (19940000), vol. 22, no. 22, pages 4673 - 4680, XP002956304
    - OSAMU GOTOH, "Significant Improvement in Accuracy of Multiple Protein. Sequence Alignments by Iterative Refinement as Assessed by Reference to Structural Alignments", J. Mol. Biol., (19960000), vol. 264, no. 4, pages 823 - 838
    - ERIC DEPIEREUXERNEST FEYTMANSMATCH-BOX, "A Fundamentally New Algorithm for the Simultaneous Alignment of Several Protein Sequences", CABIOS, (19920000), vol. 8, no. 5, pages 501 - 509
    - C. E. LAWRENCE et al., "Detecting Subtle Sequence Signals: A Gibbs Sampling Strategy for Multiple Alignment", Science, (19930000), vol. 262, no. 5131, doi:doi:10.1126/science.8211139, pages 208 - 214, XP001152872

DOI:   http://dx.doi.org/10.1126/science.8211139
    - IVO VAN WALLE et al., "Align-M - A New Algorithm for Multiple Alignment of Highly Divergent Sequences", Bioinformatics, (20040000), vol. 20, no. 9, pages 1428 - 1435
    - ALTSCHUL et al., Bull. Math. Bio., (19860000), vol. 48, pages 603 - 16
    - HENIKOFFHENIKOFF, Proc. Natl. Acad. Sci. USA, (19920000), vol. 89, pages 10915 - 19
    - ROBERTSON et al., J. Am. Chem. Soc., (19910000), vol. 113, page 2722
    - ELLMAN et al., Methods Enzymol., (19910000), vol. 202, page 301
    - CHUNG et al., Science, (19930000), vol. 259, pages 806 - 9
    - CHUNG et al., Proc. Natl. Acad. Sci. USA, (19930000), vol. 90, pages 10145 - 9
    - TURCATTI et al., J. Biol. Chem., (19960000), vol. 271, pages 19991 - 8
    - KOIDE et al., Biochem., (19940000), vol. 33, pages 7470 - 6
    - WYNNRICHARDS, Protein Sci., (19930000), vol. 2, pages 395 - 403
    - CUNNINGHAMWELLS, Science, (19890000), vol. 244, pages 1081 - 5
    - VOS et al., Science, (19920000), vol. 255, pages 306 - 12
    - SMITH et al., J. Mol. Biol., (19920000), vol. 224, pages 899 - 904
    - WLODAVER et al., FEBS Lett., (19920000), vol. 309, pages 59 - 64
    - REIDHAAR-OLSONSAUER, Science, (19880000), vol. 241, pages 53 - 7
    - BOWIESAUER, Proc. Natl. Acad. Sci. USA, (19890000), vol. 86, pages 2152 - 6
    - LOWMAN et al., Biochem., (19910000), vol. 30, pages 10832 - 7
    - DERBYSHIRE et al., Gene, (19860000), vol. 46, page 145
    - NER et al., DNA, (19880000), vol. 7, page 127
 US19870100571
 US19880173311
 US19880204171
 US19880207759
 US19880248771
 US19880257998
 US19880282328
 US19890317941
 US19890376555
 US19890394727
 US19890397169
 US19890440039
 US19900502438
 US19900520225
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.