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EP3632919
European procedure
Extract from the Register of European Patents
EP About this file: EP3632919
| EP3632919 - PHARMACEUTICAL COMPOISITIONS COMPRISING IMIDAZOTHIADIAZOLE AND IMIDAZOPYRIDAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION [Right-click to bookmark this link] | |||
| Former [2020/15] | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | ||
| [2022/23] | Status | No opposition filed within time limit Status updated on 01.09.2023 Database last updated on 24.08.2024 | |
| Former | The patent has been granted Status updated on 23.09.2022 | ||
| Former | Grant of patent is intended Status updated on 18.05.2022 | ||
| Former | Request for examination was made Status updated on 09.10.2020 | ||
| Former | The application has been published Status updated on 06.03.2020 | Most recent event Tooltip | 27.06.2024 | Change - lapse in a contracting state State(s) deleted from list of lapses: AL | published on 31.07.2024 [2024/31] | Applicant(s) | For all designated states Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | For all designated states Université de Montréal 2900 Boulevard Edouard-Montpetit Montreal, QC H3T 1J4 / CA | [2020/15] | Inventor(s) | 01 /
BANVILLE, Jacques c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 02 /
RÉMILLARD, Roger 13 Des cèdres Avenue Napierville, Québec J0J 1L0 / CA | 03 /
RUEDIGER, Edward H. c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 04 /
DEON, Daniel H. c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 05 /
GAGNON, Marc c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 06 /
DUBÉ, Laurence c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 07 /
GUY, Julia c/o Université de Montréal 2900 Édouard-Montpetit Boulevard Montréal, Québec H3T 1J4 / CA | 08 /
PRIESTLEY, Eldon Scott c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, NJ 08534 / US | 09 /
POSY, Shoshana L. c/o Bristol-Myers Squibb Company Route 206 and Province Line Road Pennington, NJ 08543 / US | 10 /
MAXWELL, Brad D. c/o Bristol-Myers Squibb Company Route 206 and Province Line Road Pennington, NJ 08543 / US | 11 /
WONG, Pancras C. c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, NJ 08534 / US | 12 /
LAWRENCE, Michael R. c/o Bristol-Myers Squibb Company 311 Pennington-Rocky Hill Road Pennington, NJ 08534 / US | 13 /
MILLER, Michael M. c/o Bristol-Myers Squibb Company Route 206 and Province Line Road Princeton, NJ 08543 / US | [2020/15] | Representative(s) | Dehns St. Bride's House 10 Salisbury Square London EC4Y 8JD / GB | [2020/15] | Application number, filing date | 19192142.8 | 24.04.2013 | [2020/15] | Priority number, date | US201261638577P | 26.04.2012 Original published format: US 201261638577 P | US201361787680P | 15.03.2013 Original published format: US 201361787680 P | [2020/15] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3632919 | Date: | 08.04.2020 | Language: | EN | [2020/15] | Type: | B1 Patent specification | No.: | EP3632919 | Date: | 26.10.2022 | Language: | EN | [2022/43] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 18.02.2020 | Classification | IPC: | C07D519/00, A61K31/433, C07D513/04, A61K31/5025, C07D487/04, A61K31/4355, A61P7/02 | [2020/15] | CPC: |
C07D487/04 (EP,CN,KR,US);
C07D513/04 (EP,CN,KR,US);
A61K31/433 (EP,KR,US);
A61K31/435 (EP,US);
A61K31/4355 (KR);
A61K31/4439 (EP,US);
A61K31/454 (EP,US);
A61K31/496 (EP,US);
A61K31/497 (EP,US);
A61K31/5025 (EP,KR,US);
A61K31/5377 (EP,US);
A61K31/5386 (EP,US);
A61K31/541 (EP,US);
A61K31/55 (EP,US);
A61K31/553 (EP,US);
A61K45/06 (EP,US);
A61K51/0453 (US);
A61P43/00 (EP);
A61P7/00 (EP);
A61P7/02 (EP);
A61P9/00 (EP);
A61P9/10 (EP);
C07B59/002 (US);
C07D519/00 (EP,CN,US);
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2020/46] |
| Former [2020/15] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | PHARMAZEUTISCHE ZUSAMMENSETUNGEN ENTHALTEND IMIDAZOTHIADIAZOL- UND IMIDAZOPYRIDAZINDERIVATE ALS PROTEASEAKTIVIERTE REZEPTOR 4 (PAR4)-INHIBITOREN ZUR BEHANDLUNG VON THROMBOZYTENAGGREGATION | [2022/23] | English: | PHARMACEUTICAL COMPOISITIONS COMPRISING IMIDAZOTHIADIAZOLE AND IMIDAZOPYRIDAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | [2022/23] | French: | COMPOSITIONS PHARMACEUTIQUES COMPRENANT DES DÉRIVÉS D'IMIDAZOTHIADIAZOLE ET D'IMIDAZOPYRIDAZINE UTILISÉS COMME INHIBITEURS DU RÉCEPTEUR 4 ACTIVÉ PAR UNE PROTÉASE (PAR4) POUR LE TRAITEMENT DE L'AGRÉGATION PLAQUETTAIRE | [2022/23] |
| Former [2020/15] | IMIDAZOTHIADIAZOL- UND IMIDAZOPYRAZINDERIVATE ALS PROTEASEAKTIVIERTE REZEPTOR 4 (PAR4)-INHIBITOREN ZUR BEHANDLUNG VON THROMBOZYTENAGGREGATION | ||
| Former [2020/15] | IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION | ||
| Former [2020/15] | DÉRIVÉS D'IMIDAZOTHIADIAZOLE ET D'IMIDAZOPYRAZINE UTILISÉS COMME INHIBITEURS DU RÉCEPTEUR 4 ACTIVÉ PAR UNE PROTÉASE (PAR4) POUR LE TRAITEMENT DE L'AGRÉGATION PLAQUETTAIRE | Examination procedure | 06.10.2020 | Amendment by applicant (claims and/or description) | 06.10.2020 | Examination requested [2020/46] | 06.10.2020 | Date on which the examining division has become responsible | 19.05.2022 | Communication of intention to grant the patent | 16.09.2022 | Fee for grant paid | 16.09.2022 | Fee for publishing/printing paid | 16.09.2022 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP13721857.4 / EP2841437 | EP17172927.0 / EP3243826 | Opposition(s) | 27.07.2023 | No opposition filed within time limit [2023/40] | Fees paid | Renewal fee | 16.08.2019 | Renewal fee patent year 03 | 16.08.2019 | Renewal fee patent year 04 | 16.08.2019 | Renewal fee patent year 05 | 16.08.2019 | Renewal fee patent year 06 | 16.08.2019 | Renewal fee patent year 07 | 31.03.2020 | Renewal fee patent year 08 | 15.04.2021 | Renewal fee patent year 09 | 21.03.2022 | Renewal fee patent year 10 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | deleted | [2024/31] |
| Former [2023/37] | AL | 26.10.2022 | Documents cited: | Search | [A]EP0005783 (BAYER AG [DE]) [A] 1-9 * Formula (I);; example -; claim - *; | [A]EP0185345 (THOMAE GMBH DR K [DE]) [A] 1-9* Formula (I);; example -; claim - *; | [A]WO2011074658 (MITSUBISHI TANABE PHARMA CORP [JP], et al) [A] 1-9 * Formulae (I), (Id), (II), (IId), (35), (36);; example -; claim - *; | [P]EP2518066 (MITSUBISHI TANABE PHARMA CORP [JP]) | by applicant | EP0667345 | EP1166785 | US2005096362 | - COUGHLIN, S.R., Nature, (20000000), vol. 407, pages 258 - 264 | - TRICOCI, P et al., N. Eng. J. Med., (20120000), vol. 366, no. 1, pages 20 - 33 | - LEE, F-Y. et al., "Synthesis of 1-Benzyl-3-(5'-hydroxymethyl-2'-furyl)indazole Analogues as Novel Antiplatelet Agents", J. Med. Chem., (20010000), vol. 44, no. 22, doi:doi:10.1021/jm010001h, pages 3746 - 3749, XP002239593 DOI: http://dx.doi.org/10.1021/jm010001h | - WU, C-C et al., "Selective Inhibition of Protease-activated Receptor 4-dependent Platelet Activation by YD-3", Thromb. Haemost., (20020000), vol. 87, pages 1026 - 1033 | - CHEN, H.S. et al., "Synthesis and platelet activity", J. Bioorg. Med. Chem., (20080000), vol. 16, pages 1262 - 1278 | - Methods in Enzymology, Academic Press, (19850000), vol. 112, pages 309 - 396 | - "Design and Application of Prodrugs", BUNDGAARD, H. et al., A Textbook of Drug Design and Development, Harwood Academic Publishers, (19910000), pages 113 - 191 | - BUNDGAARD, H., Adv. Drug Deliv. Rev., (19920000), vol. 8, pages 1 - 38 | - BUNDGAARD, H et al., J. Pharm. Sci., (19880000), vol. 77, page 285 | - KAKEYA, N et al., Chem. Pharm. Bull., (19840000), vol. 32, page 692 | - NAGIB, D.A. et al., Nature, (20110000), vol. 480, page 224 | - KAMISUKI, S. et al., Tetrahedron, (20040000), vol. 60, pages 5695 - 5700 |