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Extract from the Register of European Patents

EP About this file: EP3663296

EP3663296 - PROCESS FOR THE PREPARATION OF COMPOUNDS USEFUL FOR TREATING SPINAL MUSCULAR ATROPHY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  22.03.2024
Database last updated on 26.03.2026
FormerThe patent has been granted
Status updated on  14.04.2023
FormerGrant of patent is intended
Status updated on  06.12.2022
FormerExamination is in progress
Status updated on  24.12.2021
FormerRequest for examination was made
Status updated on  11.12.2020
FormerThe application has been published
Status updated on  08.05.2020
Most recent event   Tooltip05.09.2025Lapse of the patent in a contracting state
New state(s): CY, HU		published on 08.10.2025  [2025/41]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
For all designated states
PTC Therapeutics, Inc.
100 Corporate Court
South Plainfield, NJ 07080 / US
[2020/24]
Inventor(s)01 / RATNI, Hasane
4 Louis Pasteur
68440 Habsheim / FR
02 / GREEN, Luke
Jungstrasse 20
4056 Basel / CH
03 / NARYSHKIN, Nikolai A.
101 Windsong Circle
East Brunswick, NJ 08816 / US
04 / WEETALL, Marla L.
70 Burnham Parkway
Morristown, NJ 07960 / US
 [2020/24]
Representative(s)Schirlin, Julien
F. Hoffmann-La Roche AG
CLP - Patent Department
Grenzacherstrasse 124
4070 Basel / CH
[2020/24]
Application number, filing date19200058.611.05.2015
[2020/24]
Priority number, dateUS201461993839P15.05.2014         Original published format: US 201461993839 P
[2020/24]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP3663296
Date:10.06.2020
Language:EN
[2020/24]
Type: B1 Patent specification 
No.:EP3663296
Date:17.05.2023
Language:EN
[2023/20]
Search report(s)(Supplementary) European search report - dispatched on:EP13.05.2020
ClassificationIPC:C07D487/04, C07D519/00, A61K31/5025, // A61P21/00
[2020/24]
CPC:
A61P21/00 (EP,EA); C07D519/00 (EP,CN,EA,IL,US); C07D487/04 (EP,EA,IL,KR,US);
A61K31/5025 (EA,KR); A61K31/519 (KR); A61P21/02 (EP,EA);
A61P25/28 (EP,EA); C07D471/04 (KR) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/02]
Former [2020/24]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
Validation statesMA10.12.2020
TitleGerman:VERFAHREN ZUR HERSTELLUNG VON VERBINDUNGEN ZUR BEHANDLUNG VON SPINALER MUSKELATROPHIE[2020/24]
English:PROCESS FOR THE PREPARATION OF COMPOUNDS USEFUL FOR TREATING SPINAL MUSCULAR ATROPHY[2020/24]
French:PROCÉDÉ POUR LA PRÉPARATION DE COMPOSÉS UTILES À TRAITER L'AMYOTROPHIE SPINALE[2020/24]
Examination procedure09.12.2020Amendment by applicant (claims and/or description)
09.12.2020Examination requested  [2021/02]
09.12.2020Date on which the examining division has become responsible
23.12.2021Despatch of a communication from the examining division (Time limit: M06)
24.06.2022Reply to a communication from the examining division
07.12.2022Communication of intention to grant the patent
05.04.2023Fee for grant paid
05.04.2023Fee for publishing/printing paid
05.04.2023Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP15721701.9  / EP3143025
Divisional application(s)EP23169721.0  / EP4241772
Opposition(s)20.02.2024No opposition filed within time limit [2024/17]
Fees paidRenewal fee
27.01.2020Renewal fee patent year 03
27.01.2020Renewal fee patent year 04
19.11.2019Renewal fee patent year 05
30.03.2020Renewal fee patent year 06
11.05.2021Renewal fee patent year 07
21.03.2022Renewal fee patent year 08
21.03.2023Renewal fee patent year 09
Opt-out from the exclusive  Tooltip
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipCY11.05.2015
HU11.05.2015
BG17.05.2023
CZ17.05.2023
DK17.05.2023
EE17.05.2023
FI17.05.2023
LT17.05.2023
LV17.05.2023
MC17.05.2023
RS17.05.2023
SK17.05.2023
SM17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
[2025/41]
Former [2025/07]BG17.05.2023
CZ17.05.2023
DK17.05.2023
EE17.05.2023
FI17.05.2023
LT17.05.2023
LV17.05.2023
MC17.05.2023
RS17.05.2023
SK17.05.2023
SM17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2024/51]BG17.05.2023
CZ17.05.2023
DK17.05.2023
EE17.05.2023
FI17.05.2023
LT17.05.2023
LV17.05.2023
RS17.05.2023
SK17.05.2023
SM17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2024/10]CZ17.05.2023
DK17.05.2023
EE17.05.2023
FI17.05.2023
LT17.05.2023
LV17.05.2023
RS17.05.2023
SK17.05.2023
SM17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2024/08]FI17.05.2023
LT17.05.2023
LV17.05.2023
RS17.05.2023
SK17.05.2023
SM17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2024/03]FI17.05.2023
LT17.05.2023
LV17.05.2023
RS17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2024/01]LT17.05.2023
LV17.05.2023
RS17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2023/51]RS17.05.2023
NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2023/50]NO17.08.2023
IS17.09.2023
PT18.09.2023
Former [2023/48]NO17.08.2023
PT18.09.2023
Former [2023/46]PT18.09.2023
Documents cited:Search[AD] WO2013119916  (PTC THERAPEUTICS INC et al.)
 [AD] WO2010019326  (CARDIAC PACEMAKERS INC et al.)
 [AD] WO2009151546  (PTC THERAPEUTICS INC et al.)
by applicantWO2009151546
 WO2010019236
 WO2013119916
   CRAWFORDPARDO, NEUROBIOL. DIS., vol. 3, 1996, pages 97
   LE ET AL., HUM. MOL. GENET., vol. 14, 2005, pages 845
   PASSINI ET AL., SCI. TRANSL. MED., vol. 3, 2011, pages 72ra18
   HUA ET AL., NATURE, vol. 478, 2011, pages 123
   COADYLORSON, J NEUROSCI., vol. 30, 2010, pages 126
   "McGraw-Hill Dictionary of Chemical Terms", 1984, MCGRAW-HILL BOOK COMPANY
   ELIEL, E.WILEN, S.: "Stereochemistry of Organic Compounds", 1994, JOHN WILEY & SONS, INC.
   CAHN ET AL., ANGEW. CHEM. INTER. EDIT., vol. 5, 1966, pages 385
   F. MILLETTI ET AL., J. CHEM. INF. MODEL, vol. 47, 2007, pages 2172 - 2181
   ANSEL H. C. ET AL.: "Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems", 2004, LIPPINCOTT, WILLIAMS & WILKINS
   GENNARO A.R. ET AL.: "Remington: The Science and Practice of Pharmacy", 2000, LIPPINCOTT, WILLIAMS & WILKINS
   ROWE R.C: "Handbook of Pharmaceutical Excipients", 2005, PHARMACEUTICAL PRESS
   LIVAKSCHMITTGEN, METHODS, vol. 25, 2001, pages 402 - 8
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.