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Extract from the Register of European Patents

EP About this file: EP3749670

EP3749670 - 5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.08.2022
Database last updated on 25.09.2024
FormerThe patent has been granted
Status updated on  03.09.2021
FormerGrant of patent is intended
Status updated on  19.04.2021
FormerRequest for examination was made
Status updated on  13.11.2020
FormerThe international publication has been made
Status updated on  10.08.2019
Formerunknown
Status updated on  05.03.2019
Most recent event   Tooltip14.06.2024Lapse of the patent in a contracting state
New state(s): TR		published on 17.07.2024  [2024/29]
Applicant(s)For all designated states
Univerzita Palackeho v Olomouci
Krizkovskeho 511/8
77147 Olomouc / CZ
For all designated states
Ustav experimentalni botaniky AV CR, v.v.i.
Rozvojova 263
Lysolaje
165 02 Praha 6 / CZ
[2020/51]
Inventor(s)01 / HAVLICEK, Libor
Trnkova 1774/20
14200 Praha 4, Krc / CZ
02 / STURC, Antonin
-
deceased / CZ
03 / REZNICKOVA, Eva
Foerstrova 966/13
77900 Olomouc, Nova Ulice / CZ
04 / JORDA, Radek
Zelena 577/5
77900 Olomouc, Neredin / CZ
05 / KRYSTOF, Vladimir
Varsavske nam. 1099/7
77900 Olomouc / CZ
06 / STRNAD, Miroslav
Zapadni 659/25
77900 Olomouc, Neredin / CZ
 [2020/51]
Representative(s)Hartvichova, Katerina
HARBER IP s.r.o.
Dukelskych hrdinu 567/52
170 00 Praha 7 / CZ
[2020/51]
Application number, filing date19705912.401.02.2019
[2020/51]
WO2019CZ50002
Priority number, dateCZ2018000005805.02.2018         Original published format: CZ 20180058
[2020/51]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019149295
Date:08.08.2019
Language:EN
[2019/32]
Type: A1 Application with search report 
No.:EP3749670
Date:16.12.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 08.08.2019 takes the place of the publication of the European patent application.
[2020/51]
Type: B1 Patent specification 
No.:EP3749670
Date:06.10.2021
Language:EN
[2021/40]
Search report(s)International search report - published on:EP08.08.2019
ClassificationIPC:C07D487/04, A61P35/00, A61K31/519
[2020/51]
CPC:
C07D487/04 (EP,CZ,US); A61K31/4162 (CZ); A61K31/519 (CZ);
A61P35/00 (EP,US); A61K2121/00 (CZ)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/51]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINE ZUR BEHANDLUNG EINES LYMPHOMS[2020/51]
English:5-ALKYLTHIO-7-[(4-ARYLBENZYL)AMINO]-1(2)H-PYRAZOLO[4,3-D]PYRIMIDINES FOR TREATMENT OF LYMPHOMA[2020/51]
French:5-ALKYLTHIO-7-[(4-ARYLBENZYL) AMINO] -1 (2) H-PYRAZOLO [4,3-D] PYRIMIDINES POUR LE TRAITEMENT DU LYMPHOME[2020/51]
Entry into regional phase31.08.2020National basic fee paid 
31.08.2020Designation fee(s) paid 
31.08.2020Examination fee paid 
Examination procedure31.08.2020Examination requested  [2020/51]
31.08.2020Date on which the examining division has become responsible
20.04.2021Communication of intention to grant the patent
25.08.2021Fee for grant paid
25.08.2021Fee for publishing/printing paid
25.08.2021Receipt of the translation of the claim(s)
Opposition(s)07.07.2022No opposition filed within time limit [2022/37]
Fees paidRenewal fee
31.08.2020Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU01.02.2019
AL06.10.2021
AT06.10.2021
CY06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
IT06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
MK06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
TR06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IE01.02.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
BE28.02.2022
[2024/29]
Former [2024/25]HU01.02.2019
AL06.10.2021
AT06.10.2021
CY06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
IT06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
MK06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IE01.02.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
BE28.02.2022
Former [2024/23]AL06.10.2021
AT06.10.2021
CY06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
IT06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
MK06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IE01.02.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
BE28.02.2022
Former [2024/20]AL06.10.2021
AT06.10.2021
CY06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
IT06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IE01.02.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
BE28.02.2022
Former [2023/27]AL06.10.2021
AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
IT06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IE01.02.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
BE28.02.2022
Former [2023/10]AL06.10.2021
AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IE01.02.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
BE28.02.2022
Former [2023/09]AL06.10.2021
AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IE01.02.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
Former [2023/01]AL06.10.2021
AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SI06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
Former [2022/49]AL06.10.2021
AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
Former [2022/47]AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
LU01.02.2022
IS06.02.2022
PT07.02.2022
Former [2022/44]AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
MC06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IS06.02.2022
PT07.02.2022
Former [2022/35]AT06.10.2021
CZ06.10.2021
DK06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SK06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IS06.02.2022
PT07.02.2022
Former [2022/34]AT06.10.2021
EE06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
NL06.10.2021
PL06.10.2021
RO06.10.2021
RS06.10.2021
SE06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IS06.02.2022
PT07.02.2022
Former [2022/33]AT06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
NL06.10.2021
PL06.10.2021
RS06.10.2021
SE06.10.2021
SM06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IS06.02.2022
PT07.02.2022
Former [2022/25]AT06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
NL06.10.2021
PL06.10.2021
RS06.10.2021
SE06.10.2021
BG06.01.2022
NO06.01.2022
GR07.01.2022
IS06.02.2022
PT07.02.2022
Former [2022/24]AT06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
NL06.10.2021
PL06.10.2021
RS06.10.2021
SE06.10.2021
BG06.01.2022
GR07.01.2022
IS06.02.2022
PT07.02.2022
Former [2022/23]AT06.10.2021
ES06.10.2021
FI06.10.2021
HR06.10.2021
LT06.10.2021
LV06.10.2021
PL06.10.2021
RS06.10.2021
BG06.01.2022
PT07.02.2022
Former [2022/22]AT06.10.2021
FI06.10.2021
LT06.10.2021
RS06.10.2021
BG06.01.2022
Former [2022/21]AT06.10.2021
RS06.10.2021
BG06.01.2022
Former [2022/19]BG06.01.2022
Cited inInternational search[A]WO03082872  (USTAV EX BOTAN AV CR I OF EX B [CZ], et al) [A] 1-13 * table 4, compounds 11-91; page 23, line 7 - page 2, line 19 *
Examination   - VYMETALOVÁ LADISLAVA ET AL, "5-Substituted 3-isopropyl-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidines with anti-proliferative activity as potent and selective inhibitors of cyclin-dependent kinases", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, (20160118), vol. 110, doi:10.1016/J.EJMECH.2016.01.011, ISSN 0223-5234, pages 291 - 301, XP029415611

DOI:   http://dx.doi.org/10.1016/j.ejmech.2016.01.011
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The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.