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Extract from the Register of European Patents

EP About this file: EP3743095

EP3743095 - METHODS OF TREATING CANCER WITH DENDRITIC CELL MOBILIZING AGENTS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  03.11.2023
Database last updated on 18.01.2025
FormerRequest for examination was made
Status updated on  30.10.2020
FormerThe international publication has been made
Status updated on  03.08.2019
Formerunknown
Status updated on  16.03.2019
Most recent event   Tooltip06.05.2024New entry: Reply to examination report 
Applicant(s)For all designated states
Celldex Therapeutics, Inc.
53 Frontage Road, Suite 220
Hampton, NJ 08827 / US
For all designated states
Montefiore Medical Center
111 East 210th Street
Bronx, NY 10467 / US
For all designated states
Albert Einstein College of Medicine
1300 Morris Park Avenue
Bronx, NY 10461 / US
[2020/49]
Inventor(s)01 / KELER, Tibor
53 Frontage Road, Suite 220
Hampton, NJ 08827 / US
02 / YELLIN, Michael
138 Buckingham Road
Montclair, NJ 07043 / US
03 / GUHA, Chandan
111 East 210 Street
Bronx, NY 10467 / US
04 / OHRI, Nitin
111 East 210 Street
Bronx, NY 10467 / US
 [2020/49]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2020/49]J A Kemp LLP
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date19708908.925.01.2019
[2020/49]
WO2019US15215
Priority number, dateUS201862622474P26.01.2018         Original published format: US 201862622474 P
[2020/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019147982
Date:01.08.2019
Language:EN
[2019/31]
Type: A1 Application with search report 
No.:EP3743095
Date:02.12.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 01.08.2019 takes the place of the publication of the European patent application.
[2020/49]
Search report(s)International search report - published on:EP01.08.2019
ClassificationIPC:A61K38/19
[2020/49]
CPC:
A61K45/06 (EP,US); A61N5/1084 (US); A61K38/177 (EP,US);
A61K39/3955 (US); A61P35/00 (US); C07K16/2818 (US);
C07K16/2827 (US); C07K16/2875 (US); A61K2039/505 (EP);
A61K2039/507 (US); A61K2039/545 (US); A61N5/10 (EP);
C07K2317/21 (US); C07K2317/24 (US) (-)
C-Set:
A61K38/177, A61K2300/00 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/49]
TitleGerman:VERFAHREN ZUR BEHANDLUNG VON KREBS MIT DENDRITISCHEN ZELLMOBILISIERUNGSMITTELN[2020/49]
English:METHODS OF TREATING CANCER WITH DENDRITIC CELL MOBILIZING AGENTS[2020/49]
French:MÉTHODES DE TRAITEMENT DU CANCER À L'AIDE D'AGENTS MOBILISATEUR DE CELLULES DENDRITIQUES[2020/49]
Entry into regional phase03.08.2020National basic fee paid 
03.08.2020Designation fee(s) paid 
03.08.2020Examination fee paid 
Examination procedure03.08.2020Examination requested  [2020/49]
03.08.2020Date on which the examining division has become responsible
10.03.2021Amendment by applicant (claims and/or description)
03.11.2023Despatch of a communication from the examining division (Time limit: M06)
03.05.2024Reply to a communication from the examining division
Fees paidRenewal fee
03.08.2020Renewal fee patent year 03
27.01.2022Renewal fee patent year 04
27.01.2023Renewal fee patent year 05
29.01.2024Renewal fee patent year 06
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[I]WO2017118866  (REPLIMUNE LTD [GB]) [I] 1-25 * page 5, line 3 - page 6, paragraph 17 * * page 19, line 18 - page 21, line 5 * * page 28, line 13 - line 32; examples 2, 3, 11, 13 *;
 [XI]WO2017147553  (MEMORIAL SLOAN KETTERING CANCER CENTER [US]) [X] 5,6,9,10,12 * page 7, line 27 - page 9, line 26 * * page 16, line 33 - page 17, line 17 * * page 29, line 26 - page 30, line 33 * * page 37, line 15 - line 28; examples 6, 7, 9-14 * * page 36, line 27 - page 37, line 14 * [I] 1-4,7,8,11,13-25;
 [XI]  - Linda Hammerich et al., "In situ vaccination improves efficacy of PD-1 blockade in unresponsive lymphoma tumors through induction of a highly efficient cross-presenting dendritic cell subset expressing TLR3", BLOOD (625. Lymphoma: Pre-Clinical-Chemotherapy and Biologic Agents: Poster III), vol. 130, no. Supp 1, (20171207), Database accession no. 4106, URL: http://www.bloodjournal.org/content/130/Suppl_1/4106.abstract?sso-checked=true, (20190401), XP002790227 [X] 1-7,9,12 * the whole document * [I] 8,10,11,13-25
 [XI]  - M. A. CURRAN ET AL, "Tumor Vaccines Expressing Flt3 Ligand Synergize with CTLA-4 Blockade to Reject Preimplanted Tumors", CANCER RESEARCH, (20090908), vol. 69, no. 19, doi:10.1158/0008-5472.CAN-08-3289, ISSN 0008-5472, pages 7747 - 7755, XP055177400 [X] 5,9,13 * page 2, paragraph 4 * * page 3, paragraph 3 * * page 4, paragraph 3 * * page 5, paragraph 4 * * page 6, paragraph 5 - page 8, paragraph l * [I] 1-4,6-8,10-12,14-25

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-08-3289
 [XI]  - J. DURAISWAMY ET AL, "Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer", CANCER RESEARCH, (20131201), vol. 73, no. 23, doi:10.1158/0008-5472.CAN-13-1550, ISSN 0008-5472, pages 6900 - 6912, XP055179871 [X] 5,9,13,23 * page 6901, column r, paragraph 3 - page 6902, column l, paragraph 1 * * page 6907, column l, paragraph 3 - page 6909, column l, paragraph 1 * [I] 6,8,10,12,14-16

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-13-1550
 [I]  - PAOLA C. SACCO ET AL., "The combination of new immunotherapy and radiotherapy: A new potential treatment for locally advanced non-small cell lung cancer", CURRENT CLINICAL PHARMACOLOGY, (2017), vol. 12, pages 4 - 10, XP002790228 [I] 1-4,8-22,25 * page 7, column r, paragraph 2 * * page 8, column l, paragraph 2 - page 9, column r, paragraph 1 *
 [XPI]  - Nitin Ohri et al., "Abstract CT005: FLT3 ligand (CDX-301) and stereotactic radiotherapy for advanced non-small cell lung cancer", Cancer Research, vol. 78, no. 13, (20180701), URL: http://cancerres.aacrjournals.org/content/78/13_Supplement/CT005.short, (20190401), XP002790229 [XP] 2-4,6,7,9,11-16,20-22 * the whole document * [I] 8,10,17-19
by applicantUS4518584
 EP0212914
 US4737462
 EP0276846
 US5011912
 US5071972
 US5199942
 US5554512
 US5843423
 US6632424
 WO2011070024
 WO2011107553
 WO2011131407
 WO2011140249
 WO2013087699
 WO2013119716
 WO2013132044
 WO2013169264
 WO2014036357
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