blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP3774850

EP3774850 - CDP PROTEIN SECRETION INHIBITORS [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.01.2023
Database last updated on 25.09.2024
FormerRequest for examination was made
Status updated on  15.01.2021
FormerThe international publication has been made
Status updated on  05.10.2019
Formerunknown
Status updated on  15.05.2019
Most recent event   Tooltip27.01.2023Application deemed to be withdrawnpublished on 01.03.2023  [2023/09]
Applicant(s)For all designated states
Kezar Life Sciences
4000 Shoreline Court, Ste. 300
South San Francisco, CA 94080 / US
For all designated states
The Regents of the University of California
1111 Franklin Street, 12th Floor
Oakland, CA 94607 / US
[2021/07]
Inventor(s)01 / MCMINN, Dustin
255 Kent Road
Pacifica, CA 94044 / US
02 / TAUNTON, John William
2920 22nd St.
San Francisco, CA 94110 / US
03 / SHARP, Phillip Patrick
19 Boardman Place, Apt. 1
San Francisco, CA 94103 / US
 [2021/07]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[N/P]
Former [2021/07]Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
Application number, filing date19722269.829.03.2019
[2021/07]
WO2019US24731
Priority number, dateUS201862649718P29.03.2018         Original published format: US 201862649718 P
[2021/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019191527
Date:03.10.2019
Language:EN
[2019/40]
Type: A1 Application with search report 
No.:EP3774850
Date:17.02.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 03.10.2019 takes the place of the publication of the European patent application.
[2021/07]
Search report(s)International search report - published on:EP03.10.2019
ClassificationIPC:C07K11/02, A61K38/15
[2021/07]
CPC:
C07K11/02 (EP,US); A61K38/00 (EP,US); A61K45/06 (US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/07]
TitleGerman:CDP-PROTEIN-SEKRETIONSINHIBITOREN[2021/07]
English:CDP PROTEIN SECRETION INHIBITORS[2021/07]
French:INHIBITEURS DE SÉCRÉTION DE PROTÉINE CDP[2021/07]
Entry into regional phase14.10.2020National basic fee paid 
14.10.2020Designation fee(s) paid 
14.10.2020Examination fee paid 
Examination procedure14.10.2020Examination requested  [2021/07]
14.10.2020Date on which the examining division has become responsible
12.05.2021Amendment by applicant (claims and/or description)
01.10.2022Application deemed to be withdrawn, date of legal effect  [2023/09]
25.10.2022Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time  [2023/09]
Fees paidRenewal fee
12.03.2021Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.03.202204   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[XYI]  - YAN CHEN ET AL, "Solution-Phase Parallel Synthesis of a Pharmacophore Library of HUN-7293 Analogues: A General Chemical Mutagenesis Approach To Defining Structure-Function Properties of Naturally Occurring Cyclic (Depsi)peptides", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (20020501), vol. 124, no. 19, doi:10.1021/ja020166v, ISSN 0002-7863, pages 5431 - 5440, XP055598815 [X] 1-3,9-14,18-21,25,26,30-33,35-37,42 * the whole document, in particular abstract and Figures 1 to 10 * [Y] 4-8,15-17,22-24,27-29,34 [I] 41

DOI:   http://dx.doi.org/10.1021/ja020166v
 [Y]  - VAN PUYENBROECK VICTOR ET AL, "Inhibitors of protein translocation across membranes of the secretory pathway: novel antimicrobial and anticancer agents", CMLS CELLULAR AND MOLECULAR LIFE SCIENCES, BIRKHAUSER VERLAG, HEIDELBERG, DE, vol. 75, no. 9, doi:10.1007/S00018-017-2743-2, ISSN 1420-682X, (20180105), pages 1541 - 1558, (20180105), XP036478836 [Y] 1-42 * abstract * * section "Cotransins"; page 1545 *

DOI:   http://dx.doi.org/10.1007/s00018-017-2743-2
 [Y]  - JENNIFER L. GARRISON ET AL, "A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum", NATURE, London, (20050701), vol. 436, no. 7048, doi:10.1038/nature03821, ISSN 0028-0836, pages 285 - 289, XP055598983 [Y] 1-42 * abstract *

DOI:   http://dx.doi.org/10.1038/nature03821
 [A]  - PAATERO ANJA O ET AL, "Apratoxin Kills Cells by Direct Blockade of the Sec61 Protein Translocation Channel", CELL CHEMICAL BIOLOGY , ELSEVIER, AMSTERDAM, NL, (20160519), vol. 23, no. 5, doi:10.1016/J.CHEMBIOL.2016.04.008, ISSN 2451-9456, pages 561 - 566, XP029552460 [A] 1-42 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.chembiol.2016.04.008
 [A]  - MARKUS GREINER ET AL, "Sec62 protein level is crucial for the ER stress tolerance of prostate cancer", THE PROSTATE, (20110712), vol. 71, no. 10, doi:10.1002/pros.21324, ISSN 0270-4137, pages 1074 - 1083, XP055080540 [A] 1-42 * the whole document *

DOI:   http://dx.doi.org/10.1002/pros.21324
by applicant   - KALIES; ROMISCH, Traffic, (20150000), vol. 16, no. 10, pages 1027 - 1038
    - BERGE et al., "Pharmaceutical Salts", J. Pharm. Sci., (19770000), vol. 66, doi:doi:10.1002/jps.2600660104, pages 1 - 19, XP002675560

DOI:   http://dx.doi.org/10.1002/jps.2600660104
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.