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Extract from the Register of European Patents

EP About this file: EP3794145

EP3794145 - INFERRING SELECTION IN WHITE BLOOD CELL MATCHED CELL-FREE DNA VARIANTS AND/OR IN RNA VARIANTS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  13.01.2023
Database last updated on 03.10.2024
FormerRequest for examination was made
Status updated on  19.02.2021
FormerThe international publication has been made
Status updated on  22.11.2019
Formerunknown
Status updated on  15.06.2019
Most recent event   Tooltip17.09.2024Change: Despatch of examination report + time limit 
Applicant(s)For all designated states
Grail, Inc.
1525 O'Brien Drive
Menlo Park, California 94025 / US
[2024/35]
Former [2022/02]For all designated states
Grail, LLC
1525 O'Brien Drive
Menlo Park, CA 94025 / US
Former [2021/12]For all designated states
Grail, Inc.
1525 O'Brien Drive
Menlo Park, California 94025 / US
Inventor(s)01 / VENN, Oliver Claude
c/o GRAIL, INC.
1525 O'Brien Drive
Menlo Park, California 94025 / US
02 / HUBBELL, Earl
c/o GRAIL, INC.
1525 O'Brien Drive
Menlo Park, California 94025 / US
 [2021/12]
Representative(s)Murgitroyd & Company
165-169 Scotland Street
Glasgow G5 8PL / GB
[N/P]
Former [2021/12]Murgitroyd & Company
Murgitroyd House
165-169 Scotland Street
Glasgow G5 8PL / GB
Application number, filing date19728842.620.05.2019
[2021/12]
WO2019US33168
Priority number, dateUS201862673779P18.05.2018         Original published format: US 201862673779 P
[2021/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019222757
Date:21.11.2019
Language:EN
[2019/47]
Type: A1 Application with search report 
No.:EP3794145
Date:24.03.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 21.11.2019 takes the place of the publication of the European patent application.
[2021/12]
Search report(s)International search report - published on:EP21.11.2019
ClassificationIPC:C12Q1/6869, G16B30/00, G16B40/00
[2021/12]
CPC:
C12Q1/6869 (EP); G16B20/20 (US); C12N15/1089 (US);
C12Q1/6874 (US); G16B30/00 (EP); G16B30/10 (US);
G16B40/00 (EP) (-)
C-Set:
C12Q1/6869, C12Q2537/165 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/12]
TitleGerman:ABLEITUNG DER AUSWAHL IN WEISSEN BLUTZELLEN ANGEPASSTEN ZELLFREIEN DNA-VARIANTEN UND/ODER IN RNA-VARIANTEN[2021/12]
English:INFERRING SELECTION IN WHITE BLOOD CELL MATCHED CELL-FREE DNA VARIANTS AND/OR IN RNA VARIANTS[2021/12]
French:DÉDUCTION DE SÉLECTION DE VARIANTS D'ADN LIBRES CIRCULANTS CORRESPONDANT À DES GLOBULES BLANCS ET/OU DE VARIANTS D'ARN[2021/12]
Entry into regional phase14.12.2020National basic fee paid 
14.12.2020Designation fee(s) paid 
14.12.2020Examination fee paid 
Examination procedure14.12.2020Examination requested  [2021/12]
14.12.2020Date on which the examining division has become responsible
23.07.2021Amendment by applicant (claims and/or description)
13.01.2023Despatch of a communication from the examining division (Time limit: M06)
20.07.2023Reply to a communication from the examining division
29.05.2024Despatch of a communication from the examining division (Time limit: M06)
Fees paidRenewal fee
12.05.2021Renewal fee patent year 03
16.03.2022Renewal fee patent year 04
14.03.2023Renewal fee patent year 05
13.03.2024Renewal fee patent year 06
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See the Register of the Unified Patent Court for opt-out data
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Cited inInternational search[A]  - Elaine R Mardis Et Al., "Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome", The New England Journal of Medicine, United States, doi:10.1056/NEJMoa0903840, (20090910), pages 1058 - 1066, URL: http://www.nejm.org/doi/pdf/10.1056/NEJMoa0903840, (20161124), XP055322685 [A] 1-115,168,261,262 * page 1058 "Results" *

DOI:   http://dx.doi.org/10.1056/NEJMoa0903840
 [A]  - E PAPAEMMANUIL ET AL, "Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts", THE NEW ENGLAND JOURNAL OF MEDICINE, (20110926), vol. 365, doi:10.1056/NEJMoa1103283), pages 1384 - 1395, XP055053063 [A] 1-115,168,261,262 * title; page 1384 "Methods" and "Results" *

DOI:   http://dx.doi.org/10.1056/NEJMoa1103283)
 [XY]  - MARTINCORENA IÑIGO ET AL, "Universal Patterns of Selection in Cancer and Somatic Tissues", CELL, (20171116), vol. 171, no. 5, doi:10.1016/J.CELL.2017.09.042, ISSN 0092-8674, page 1029, XP085251281 [X] 168,261,262 * the whole document * [Y] 1-115

DOI:   http://dx.doi.org/10.1016/j.cell.2017.09.042
 [XY]  - Iñigo Martincorena ET AL, "Supplemental Information Universal Patterns of Selection in Cancer and Somatic Tissues", Cell, (20171116), pages 1 - 6, URL: https://www.cell.com/cms/10.1016/j.cell.2017.09.042/attachment/7cc08032-7493-4f38-99cb-f4a4c3fab608/mmc1.pdf, (20190802), XP055610586 [X] 168,261,262 * Table S1 * [Y] 1-115
 [Y]  - FEDYANIN MIKHAIL ET AL, "Circulating tumor cells and circulating tumor DNA in colon cancer", MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY, SPRINGER, AT, vol. 9, no. 2, doi:10.1007/S12254-016-0263-7, ISSN 1865-5041, (20160510), pages 88 - 92, (20160510), XP035991876 [Y] 1-115 * abstract *

DOI:   http://dx.doi.org/10.1007/s12254-016-0263-7
 [Y]  - SARAH-JANE DAWSON ET AL, "Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer", THE NEW ENGLAND JOURNAL OF MEDICINE, - NEJM -, US, (20130328), vol. 368, no. 13, doi:10.1056/NEJMoa1213261, ISSN 0028-4793, pages 1199 - 1209, XP055494258 [Y] 1-115 * abstract *

DOI:   http://dx.doi.org/10.1056/NEJMoa1213261
 [Y]  - HEITZER ELLEN, "Clinical utility of circulating tumor DNA in human cancers", MAGAZINE OF EUROPEAN MEDICAL ONCOLOGY, SPRINGER, AT, vol. 8, no. 4, doi:10.1007/S12254-015-0217-5, ISSN 1865-5041, (20150702), pages 222 - 226, (20150702), XP035957906 [Y] 1-115 * abstract *

DOI:   http://dx.doi.org/10.1007/s12254-015-0217-5
 [Y]  - MINGCHAO XIE ET AL, "Age-related mutations associated with clonal hematopoietic expansion and malignancies", NATURE MEDICINE, New York, (20141019), vol. 20, no. 12, doi:10.1038/nm.3733, ISSN 1078-8956, pages 1472 - 1478, XP055246879 [Y] 2-115 * abstract *

DOI:   http://dx.doi.org/10.1038/nm.3733
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