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Extract from the Register of European Patents

EP About this file: EP3746082

EP3746082 - METHODS FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.12.2023
Database last updated on 10.07.2024
FormerExamination is in progress
Status updated on  16.02.2023
FormerRequest for examination was made
Status updated on  06.11.2020
FormerThe international publication has been made
Status updated on  10.08.2019
Most recent event   Tooltip15.12.2023Application deemed to be withdrawnpublished on 17.01.2024  [2024/03]
Applicant(s)For all designated states
Fred Hutchinson Cancer Center
1100 Fairview Avenue North
Seattle, WA 98109 / US
[2022/23]
Former [2020/50]For all designated states
Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North
Seattle, WA 98109-1024 / US
Inventor(s)01 / TAPSCOTT, Stephen, J.
3419 South Dose Terrace
Seattle, WA 98144 / US
02 / SHADLE, Sean
5710 29th Ave NE
Seattle, WA 98107 / US
03 / CAMPBELL, Amy
3312 Valentia St.
Denver, CO 80238 / US
 [2021/08]
Former [2020/50]01 / TAPSCOTT, Stephen, J.
3419 South Dose Terrace
Seattle, WA 98144 / US
02 / SHADLE, Sean
5710 29th Ave NE
Seattle, WA 98107 / US
03 / CAMPBELL, Amy
5810 Coven PI NE 407
Seattle, WA 98105 / US
Representative(s)Tombling, Adrian George
Withers & Rogers LLP
2 London Bridge
London SE1 9RA / GB
[N/P]
Former [2020/50]Tombling, Adrian George
Withers & Rogers LLP
4 More London Riverside
London SE1 2AU / GB
Application number, filing date19748161.701.02.2019
[2020/50]
WO2019US16315
Priority number, dateUS201862625881P02.02.2018         Original published format: US 201862625881 P
[2020/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019152820
Date:08.08.2019
Language:EN
[2019/32]
Type: A1 Application with search report 
No.:EP3746082
Date:09.12.2020
Language:EN
The application published by WIPO in one of the EPO official languages on 08.08.2019 takes the place of the publication of the European patent application.
[2020/50]
Search report(s)International search report - published on:US08.08.2019
(Supplementary) European search report - dispatched on:EP09.11.2021
ClassificationIPC:A61K31/52, A61K31/445, A61K31/496, A61K31/517, A61K31/4439, A61K31/5377, A61P21/00, A61K35/34, C12N15/00, C12N15/113, A61K31/7088
[2021/49]
CPC:
A61K35/34 (EP,US); A61K31/7088 (EP); A61K38/1709 (US);
A61P21/00 (EP); C12N15/113 (EP,US); C12N15/1137 (EP);
C12N2310/14 (EP); C12N2310/20 (EP) (-)
Former IPC [2020/50]A61K31/52, A61K31/445, A61K31/496, A61K31/517, A61K31/4439, A61K31/5377, A61P21/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/50]
TitleGerman:VERFAHREN ZUR BEHANDLUNG VON FAZIOSKAPULOHUMERALER MUSKELDYSTROPHIE[2020/50]
English:METHODS FOR TREATING FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY[2020/50]
French:MÉTHODES PERMETTANT DE TRAITER LA DYSTROPHIE MUSCULAIRE FACIO-SCAPULO-HUMÉRALE[2020/50]
Entry into regional phase31.08.2020National basic fee paid 
31.08.2020Search fee paid 
31.08.2020Designation fee(s) paid 
31.08.2020Examination fee paid 
Examination procedure31.08.2020Examination requested  [2020/50]
24.05.2022Amendment by applicant (claims and/or description)
15.02.2023Despatch of a communication from the examining division (Time limit: M06)
26.08.2023Application deemed to be withdrawn, date of legal effect  [2024/03]
13.09.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2024/03]
Fees paidRenewal fee
25.02.2021Renewal fee patent year 03
25.02.2022Renewal fee patent year 04
27.02.2023Renewal fee patent year 05
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Documents cited:Search[I]WO2016124793  (ASS INST DE MYOLOGIE [FR], et al) [I] 1-5,13-15 * see claims *;
 [E]WO2019071147  (FULCRUM THERAPEUTICS INC [US]) [E] 6-9,12* see claims and examples 9-10 *;
 [I]  - ANSSEAU ET AL, "Antisense Oligonucleotides Used to Target the DUX4 mRNA as Therapeutic Approaches in FaciosScapuloHumeral Muscular Dystrophy (FSHD)", GENES, (20170303), vol. 8, no. 93, doi:10.3390/genes8030093, pages 1 - 21, XP055684651 [I] 1-5,13-15 * abstract *

DOI:   http://dx.doi.org/10.3390/genes8030093
 [I]  - LEMMERS RICHARD JLF ET AL, "Deep characterization of a common D4Z4 variant identifies biallelicDUX4expression as a modifier for disease penetrance in FSHD2", EUROPEAN JOURNAL OF HUMAN GENETICS, KARGER, BASEL, CH, vol. 26, no. 1, doi:10.1038/S41431-017-0015-0, ISSN 1018-4813, (20171121), pages 94 - 106, (20171121), XP036847108 [I] 13-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/s41431-017-0015-0
 [A]  - JIN SEUNG-GI ET AL, "MBD3L2 Interacts with MBD3 and Components of the NuRD Complex and Can Oppose MBD2-MeCP1-mediated Methylation Silencing", JOURNAL OF BIOLOGICAL CHEMISTRY, US, (20050401), vol. 280, no. 13, doi:10.1074/jbc.M413492200, ISSN 0021-9258, pages 12700 - 12709, XP055856181 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1074/jbc.M413492200
 [T]  - Desimone Alec M. ET AL, "Facioscapulohumeral Muscular Dystrophy", Comprehensive Physiology, Hoboken, NJ, USA, John Wiley & Sons, Inc., (20170912), pages 1229 - 1279, doi:10.1002/cphy.c160039, ISBN 978-0-470-65071-4, XP055856173 [T] * see the whole document, especially tables 3-4 *

DOI:   http://dx.doi.org/10.1002/cphy.c160039
International search[X]US2013288976  (VAN DER MAAREL SILVERE M [NL], et al) [X] 7-9, 10/7-9 * ; figure 21; paragraphs [0011], [0437], [0438] *;
 [Y]WO2017201585  (GENEA IP HOLDINGS PTY LTD [AU]) [Y] 1-4, 5/1-4, 6/5/1-4 * ; paragraphs [0004], [0014], [0042], [0052], [0055], [0159], [0194] *;
 [Y]US2010292348  (ZHOU CHONGWU [US], et al) [Y] 1-2, 4, 5/1-2, 5/4, 6/5/1-2, 6/5/4 * ; paragraph [0043] *;
 [A]US2018016577  (DUMONCEAUX JULIE [FR], et al) [A] 15-17 * ; paragraphs [0001], [0005], [0010], [0046], [0088], [0090] *
 [Y]  - BROWN et al., "ATP-Dependent Chromatin Remodeling Complexes In Xenopus Development", Doctoral, (20101200), pages 1 - 138, URL: https://scholarworks.alaska.edu/bitstream/handle/11122/9047/Brown_E_2010.pdf?sequence=1, (20190315), XP055627939 [Y] 3, 5/3, 6/5/3 * ; page 35, first paragraph. *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.