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Extract from the Register of European Patents

EP About this file: EP3747909

EP3747909 - ANTICANCER AGENT [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  03.05.2024
Database last updated on 06.07.2024
FormerRequest for examination was made
Status updated on  06.11.2020
FormerThe international publication has been made
Status updated on  10.08.2019
Most recent event   Tooltip07.05.2024New entry: Despatch of examination report + time limit 
Applicant(s)For all designated states
Osaka University
1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
[2022/16]
Former [2020/50]For all designated states
Osaka University
1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
For all designated states
Tokyo Institute of Technology
2-12-1, Ookayama
Meguro-ku
Tokyo 152-8550 / JP
Inventor(s)01 / MORI, Masaki
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
02 / ISHII, Hideshi
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
03 / KONNO, Masamitsu
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
04 / EGUCHI, Hidetoshi
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
05 / HARAGUCHI, Naotsugu
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
06 / TOSHIYAMA, Reishi
c/o OSAKA UNIVERSITY, 1-1, Yamadaoka
Suita-shi, Osaka 565-0871 / JP
07 / NISHIYAMA, Nobuhiro
c/o TOKYO INSTITUTE OF TECHNOLOGY, 2-12-1,
Ookayama, Meguro-ku
Tokyo 152-8550 / JP
08 / TAKEMOTO, Hiroyasu
c/o TOKYO INSTITUTE OF TECHNOLOGY, 2-12-1,
Ookayama, Meguro-ku
Tokyo 152-8550 / JP
 [2020/50]
Representative(s)Müller-Boré & Partner Patentanwälte PartG mbB
Friedenheimer Brücke 21
80639 München / DE
[2020/50]
Application number, filing date19748189.830.01.2019
[2020/50]
WO2019JP03150
Priority number, dateJP2018001367830.01.2018         Original published format: JP 2018013678
[2020/50]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019151320
Date:08.08.2019
Language:JA
[2019/32]
Type: A1 Application with search report 
No.:EP3747909
Date:09.12.2020
Language:EN
[2020/50]
Search report(s)International search report - published on:JP08.08.2019
(Supplementary) European search report - dispatched on:EP12.08.2021
ClassificationIPC:C07K14/00, C07C255/00, A61K31/165, A61K31/198, A61K31/785, A61K47/42, A61K47/60, A61K47/64, A61P35/00
[2021/37]
CPC:
C07K14/001 (EP); A61K47/64 (US); A61K31/513 (EP,US);
A61K31/704 (EP,US); A61K33/243 (EP,US); A61K45/06 (EP);
A61K47/42 (EP); A61K47/60 (EP); A61K47/645 (EP);
A61K9/0019 (EP); A61P35/00 (EP,US); C07K5/0202 (EP);
C12N9/99 (EP); A61K38/00 (EP) (-)
C-Set:
A61K31/513, A61K2300/00 (EP);
A61K31/704, A61K2300/00 (EP);
A61K33/243, A61K2300/00 (EP)
Former IPC [2020/50]C07K19/00, A61K31/198, A61K31/785, A61K45/00, A61K47/34, A61K47/42, A61K47/60, A61K47/64, A61P35/00, A61P43/00, C07K5/06, C07K14/81, C12N9/99, C12N9/64
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2020/50]
TitleGerman:ANTIKREBSMITTEL[2020/50]
English:ANTICANCER AGENT[2020/50]
French:AGENT ANTICANCÉREUX[2020/50]
Entry into regional phase10.08.2020Translation filed 
13.08.2020National basic fee paid 
13.08.2020Search fee paid 
13.08.2020Designation fee(s) paid 
13.08.2020Examination fee paid 
Examination procedure05.08.2019Request for preliminary examination filed
International Preliminary Examining Authority: JP
13.08.2020Examination requested  [2020/50]
01.02.2022Amendment by applicant (claims and/or description)
06.05.2024Despatch of a communication from the examining division (Time limit: M04)
Fees paidRenewal fee
13.08.2020Renewal fee patent year 03
18.01.2022Renewal fee patent year 04
20.01.2023Renewal fee patent year 05
11.01.2024Renewal fee patent year 06
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Documents cited:Search[A]WO2010005740  (BIND BIOSCIENCES INC [US], et al) [A] 1-15 * page 5 ** page 31, line 25 *;
 [X]EP2258397  (NIPPON KAYAKU KK [JP]) [X] 1-15 * general formula (II); test example 2; paragraph [0021]; example 5; claims 1-24 *;
 [X]WO2013024048  (ASCENDIS PHARMA AS [DK], et al) [X] 1-15 * pages 26 to 29; pages 33 to 36; page 92, line 4; examples 2,3; claims 1-14 *;
 [X]WO2017170845  (NANOCARRIER CO LTD [JP]) [X] 1-15 * paragraph [0014]; claims 1-20 *
International search[Y]JP2002515418  (EXPRESSION GENETICS, INC.) [Y] 1-15 * , abstract, background & US 6177274 Bl, abstract, background of the invention & WO 1999/059546 A1 & EP 1083882 A *;
 [Y]JP2017105800  (UNIV TOKYO, et al) [Y] 1-15 * , abstract, examples & US 2018/0153920 A, abstract, examples & WO 2013/162041 A & EP 2842546 A1 *;
 [Y]  - YAMASHITA, MASAFUMI et al., "A CD 13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma", International journal of oncology, (20160000), vol. 49, pages 89 - 98, XP055628479 [Y] 1-15 * , abstract, introduction, results *

DOI:   http://dx.doi.org/10.3892/ijo.2016.3496
 [Y]  - ZHOU, ZHUXIAN et al., "A multifunctional PEG-PLL drug conjugate forming redox-responsive nanoparticles for intracellular drug delivery", Journal of materials chemistry B, (20150000), vol. 3, pages 7594 - 7603, XP055628483 [Y] 1-15 * , abstract, materials *

DOI:   http://dx.doi.org/10.1039/C5TB01027F
 [PX]  - TOSHIYAMA, REISHI et al., "Poly(ethylene glycol)- poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells", Oncogene, (20180800), vol. 38, no. 2, pages 244 - 260, XP036668959 [PX] 1-15 * , materials and methods, results, fig. 2 *

DOI:   http://dx.doi.org/10.1038/s41388-018-0406-x
by applicant   - YAMASHITA MWADA HEGUCHI HOGAWA HYAMADA DNODA T et al., "A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma", Int J Oncol, (20160000), vol. 49, doi:10.3892/ijo.2016.3496, pages 89 - 98, XP055628479

DOI:   http://dx.doi.org/10.3892/ijo.2016.3496
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.