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Extract from the Register of European Patents

EP About this file: EP3762493

EP3762493 - SYSTEMS AND METHODS FOR ASSESSING COLORECTAL CANCER MOLECULAR SUBTYPE AND RISK OF RECURRENCE AND FOR DETERMINING AND ADMINISTERING TREATMENT PROTOCOLS BASED THEREON [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  11.12.2020
Database last updated on 24.08.2024
FormerThe international publication has been made
Status updated on  14.09.2019
Most recent event   Tooltip08.05.2024New entry: Additional fee for renewal fee: despatch of communication + time limit 
Applicant(s)For all designated states
University of Notre Dame du Lac
1400 East Angela Boulevard.
South Bend, IN 46617 / US
[2021/02]
Inventor(s)01 / BUECHLER, Steven
51210 Lexingham Drive
Granger, Indiana 46530 / US
 [2021/02]
Representative(s)Appleyard Lees IP LLP
15 Clare Road
Halifax HX1 2HY / GB
[2021/02]
Application number, filing date19764240.807.03.2019
[2021/02]
WO2019US21234
Priority number, dateUS201862640157P08.03.2018         Original published format: US 201862640157 P
[2021/02]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019173644
Date:12.09.2019
Language:EN
[2019/37]
Type: A1 Application with search report 
No.:EP3762493
Date:13.01.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 12.09.2019 takes the place of the publication of the European patent application.
[2021/02]
Search report(s)International search report - published on:US12.09.2019
(Supplementary) European search report - dispatched on:EP22.10.2021
ClassificationIPC:C12N15/10, C12Q1/68, C40B40/06
[2021/02]
CPC:
C12Q1/6886 (EP,US); G16B20/00 (EP); G16B25/10 (US);
G16B30/00 (US); G16B40/00 (US); G16H10/40 (US);
G16H20/40 (US); G16H50/20 (US); G16H50/30 (EP);
G16H70/60 (US); C12Q2600/106 (EP); C12Q2600/112 (EP,US);
C12Q2600/118 (EP,US); C12Q2600/154 (EP); C12Q2600/156 (EP,US);
C12Q2600/158 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/02]
TitleGerman:SYSTEME UND VERFAHREN ZUR BEURTEILUNG DES MOLEKULAREN SUBTYPS UND DES RÜCKFALLRISIKOS VON DARMKREBS UND ZUR BESTIMMUNG UND VERABREICHUNG DARAUF BASIERENDER BEHANDLUNGSPROTOKOLLE[2021/02]
English:SYSTEMS AND METHODS FOR ASSESSING COLORECTAL CANCER MOLECULAR SUBTYPE AND RISK OF RECURRENCE AND FOR DETERMINING AND ADMINISTERING TREATMENT PROTOCOLS BASED THEREON[2021/02]
French:SYSTÈMES ET PROCÉDÉS D'ÉVALUATION D'UN SOUS-TYPE MOLÉCULAIRE DE CANCER COLORECTAL ET RISQUE DE RÉCURRENCE ET DÉTERMINATION ET ADMINISTRATION DE PROTOCOLES DE TRAITEMENT BASÉS SUR CES DERNIERS[2021/02]
Entry into regional phase07.10.2020National basic fee paid 
07.10.2020Search fee paid 
07.10.2020Designation fee(s) paid 
07.10.2020Examination fee paid 
Examination procedure07.10.2020Examination requested  [2021/02]
09.05.2022Amendment by applicant (claims and/or description)
Fees paidRenewal fee
12.03.2021Renewal fee patent year 03
14.01.2022Renewal fee patent year 04
21.03.2023Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
31.03.202406   M06   Not yet paid
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Documents cited:Search[Y]WO2011063274  (GENOMIC HEALTH INC [US], et al) [Y] 1-15 * claims 1-18 * * table 17 * * paragraph [0092] - paragraph [0133] *;
 [A]WO2013052480  (UNIV TEXAS [US]) [A] 1-15 * claims 1-17 ** paragraphs [0003] - [0006] *;
 [E]WO2019173647  (UNIV NOTRE DAME DU LAC [US]) [E] 1-15 * claims 1-19 * * tables 3a-3d *;
 [T]  - BUECHLER STEVEN A. ET AL, "ColoType: a forty gene signature for consensus molecular subtyping of colorectal cancer tumors using whole-genome assay or targeted RNA-sequencing", SCIENTIFIC REPORTS, vol. 10, no. 1, doi:10.1038/s41598-020-69083-y, (20200721), URL: http://www.nature.com/articles/s41598-020-69083-y, XP055788551 [T] * the whole document *

DOI:   http://dx.doi.org/10.1038/s41598-020-69083-y
 [XY]  - JUSTIN GUINNEY ET AL, "The consensus molecular subtypes of colorectal cancer", NATURE MEDICINE, New York, (20151012), vol. 21, no. 11, doi:10.1038/nm.3967, ISSN 1078-8956, pages 1350 - 1356, XP055360839 [X] 11-15 * the whole document * [Y] 1-10

DOI:   http://dx.doi.org/10.1038/nm.3967
 [XY]  - ANITA SVEEN ET AL, "Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies", CLINICAL CANCER RESEARCH, US, (20171214), vol. 24, no. 4, doi:10.1158/1078-0432.CCR-17-1234, ISSN 1078-0432, pages 794 - 806, XP055465813 [X] 1,11-15 * the whole document * [Y] 2-10

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-17-1234
 [XY]  - Sveen Anita ET AL, "Supplementary Table S2. Overview and CMS groups of CRC cell lines a) Cell lines used for genomic analyses (various sources) Cell lines derived from unique patients Cell line (unique) Alternative names Primary tissue Metastasis", (20180215), URL: https://clincancerres.aacrjournals.org/highwire/filestream/159347/field_highwire_adjunct_files/1/182615_3_supp_4417047_p04pbf.xlsx, (20211014), XP055851345 [X] 1,11-15 * the whole document * * tables S7-S8 * [Y] 2-10
 [XY]  - PETER W. EIDE ET AL, "CMScaller: an R package for consensus molecular subtyping of colorectal cancer pre-clinical models", SCIENTIFIC REPORTS, (20171130), vol. 7, no. 1, doi:10.1038/s41598-017-16747-x, XP055465931 [X] 11-15 * the whole document * [Y] 1-15

DOI:   http://dx.doi.org/10.1038/s41598-017-16747-x
 [XA]  - PAWEL KARPINSKI ET AL, "Immunological landscape of consensus clusters in colorectal cancer", ONCOTARGET, (20171027), vol. 8, no. 62, doi:10.18632/oncotarget.22169, pages 105299 - 105311, XP055683316 [X] 11-15 * the whole document * * figure 3; table 1 * [A] 1-10

DOI:   http://dx.doi.org/10.18632/oncotarget.22169
 [A]  - RODRIGUEZ-SALAS NURIA ET AL, "Clinical relevance of colorectal cancer molecular subtypes", CRITICAL REVIEWS IN ONCOLOGY/HEMATOLOGY, (20170101), vol. 109, doi:10.1016/J.CRITREVONC.2016.11.007, ISSN 1040-8428, pages 9 - 19, XP029857764 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.critrevonc.2016.11.007
 [A]  - FRATAMICO ROBERTO S ET AL, "Molecular Profiling in Colon Cancer: Where Are We Now?", CURRENT COLORECTAL CANCER REPORTS, SPRINGER US, BOSTON, vol. 13, no. 5, doi:10.1007/S11888-017-0385-2, ISSN 1556-3790, (20170826), pages 362 - 369, (20170826), XP036347711 [A] 1-15 * the whole document * * table 1 *

DOI:   http://dx.doi.org/10.1007/s11888-017-0385-2
International search[X]US2010190173  (COWENS WAYNE [US], et al) [X] 63-71 * ; abstract; paragraphs [0014], [0017], [0022], [0035], [0040], [0088], [0089], [0100], [0139], [0167], [0201] *;
 [A]WO2017182656  (VIB VZW [BE], et al) [A] 1-7, 8/1-7, 9-48, 49/47-48, 50/49/47-48, 51/49/47-48, 52/51/49/47-48, 53/51/49/47-48, 54-62, 72-88, 91-92, 94-100 * ; page 3, lines 31-33; page 11, lines 31-33; page 23, lines 26-31; figure 2; table 2 *;
 [A]  - LINNEKAMP et al., "Consensus Molecular Subtypes Of Colorectal Cancer Are Recapitulated In In Vitro And In Vivo Models", Cell Death & Differentiation, (20180105), vol. 25, no. 3, doi:doi:10.1038/s41418-017-0011-5, pages 616 - 633, XP036444064 [A] 1-7, 8/1-7, 9-48, 49/47-48, 50/49/47-48, 51/49/47-48, 52/51/49/47-48, 53/51/49/47-48, 54-62, 72-88, 91-92, 94-100 * ; abstract; page 631, column 2, second paragraph. https://doi.org/10.1038/s41418-017-0011-5 *

DOI:   http://dx.doi.org/10.1038/s41418-017-0011-5
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