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Extract from the Register of European Patents

EP About this file: EP3773686

EP3773686 - ALKALINE PHOSPHATASE AGENTS FOR TREATMENT OF RADIATION DISORDERS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.04.2024
Database last updated on 09.09.2024
FormerThe patent has been granted
Status updated on  05.05.2023
FormerGrant of patent is intended
Status updated on  13.03.2023
FormerRequest for examination was made
Status updated on  15.01.2021
FormerThe international publication has been made
Status updated on  28.09.2019
Most recent event   Tooltip24.05.2024Lapse of the patent in a contracting state
New state(s): IT		published on 26.06.2024  [2024/26]
Applicant(s)For all designated states
Theriva Biologics, Inc.
9605 Medical Center Drive
Suite 270
Rockville, MD 20850 / US
[2023/23]
Former [2021/07]For all designated states
Synthetic Biologics, Inc.
9605 Medical Center Drive
Suite 270
Rockville, MD 20850 / US
Inventor(s)01 / KALEKO, Michael
c/o Synthetic Biologics, Inc. 9605 Medical Center
Drive, Suite 270
Rockville, MD 20850 / US
02 / FURLAN FREGUIA, Christian
c/o Synthetic Biologics, Inc. 9605 Medical Center
Drive, Suite 270
Rockville, MD 20850 / US
03 / CONNELLY, Sheila
c/o Synthetic Biologics, Inc. 9605 Medical Center
Drive, Suite 270
Rockville, MD 20850 / US
 [2021/07]
Representative(s)Boxall, Sarah Jane
Boxall IPM Ltd 9 King Street
Sandwich Kent CT13 9BT / GB
[2021/07]
Application number, filing date19770253.320.03.2019
[2021/07]
WO2019US23143
Priority number, dateUS201862645469P20.03.2018         Original published format: US 201862645469 P
US201862714398P03.08.2018         Original published format: US 201862714398 P
[2021/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019183209
Date:26.09.2019
Language:EN
[2019/39]
Type: A1 Application with search report 
No.:EP3773686
Date:17.02.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 26.09.2019 takes the place of the publication of the European patent application.
[2021/07]
Type: B1 Patent specification 
No.:EP3773686
Date:07.06.2023
Language:EN
[2023/23]
Search report(s)International search report - published on:US26.09.2019
(Supplementary) European search report - dispatched on:EP23.11.2021
ClassificationIPC:A61K38/46, A61K45/06, A61P39/00
[2021/51]
CPC:
A61K45/06 (EP); A61K38/465 (EP,US); A61K35/74 (EP);
A61K9/0053 (US); A61P1/00 (EP); A61P39/00 (EP,US);
C12Y301/03001 (US) (-)
C-Set:
A61K35/74, A61K2300/00 (EP);
A61K38/465, A61K2300/00 (EP)
Former IPC [2021/07]A61K38/46, A61K45/06
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/07]
Extension statesBANot yet paid
MENot yet paid
Validation statesKHNot yet paid
MANot yet paid
MDNot yet paid
TNNot yet paid
TitleGerman:ALKALISCHE PHOSPHATASEMITTEL ZUR BEHANDLUNG VON BESTRAHLUNGSSTÖRUNGEN[2021/07]
English:ALKALINE PHOSPHATASE AGENTS FOR TREATMENT OF RADIATION DISORDERS[2021/07]
French:AGENTS AU PHOSPHATASE ALCALINE POUR LE TRAITEMENT DE TROUBLES DUS À UNE EXPOSITION À DES RADIATIONS[2021/07]
Entry into regional phase14.10.2020National basic fee paid 
14.10.2020Search fee paid 
14.10.2020Designation fee(s) paid 
14.10.2020Examination fee paid 
Examination procedure14.10.2020Examination requested  [2021/07]
09.06.2022Amendment by applicant (claims and/or description)
13.03.2023Communication of intention to grant the patent
25.04.2023Fee for grant paid
25.04.2023Fee for publishing/printing paid
25.04.2023Receipt of the translation of the claim(s)
Divisional application(s)EP23177425.8  / EP4275761
Opposition(s)08.03.2024No opposition filed within time limit [2024/20]
Fees paidRenewal fee
18.03.2021Renewal fee patent year 03
17.03.2022Renewal fee patent year 04
07.03.2023Renewal fee patent year 05
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipAT07.06.2023
CZ07.06.2023
DK07.06.2023
EE07.06.2023
ES07.06.2023
FI07.06.2023
HR07.06.2023
IT07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
PL07.06.2023
RO07.06.2023
RS07.06.2023
SE07.06.2023
SI07.06.2023
SK07.06.2023
SM07.06.2023
NO07.09.2023
GR08.09.2023
IS07.10.2023
PT09.10.2023
[2024/26]
Former [2024/25]AT07.06.2023
CZ07.06.2023
DK07.06.2023
EE07.06.2023
ES07.06.2023
FI07.06.2023
HR07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
PL07.06.2023
RO07.06.2023
RS07.06.2023
SE07.06.2023
SI07.06.2023
SK07.06.2023
SM07.06.2023
NO07.09.2023
GR08.09.2023
IS07.10.2023
PT09.10.2023
Former [2024/22]AT07.06.2023
CZ07.06.2023
DK07.06.2023
EE07.06.2023
ES07.06.2023
FI07.06.2023
HR07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
PL07.06.2023
RO07.06.2023
RS07.06.2023
SE07.06.2023
SK07.06.2023
SM07.06.2023
NO07.09.2023
GR08.09.2023
IS07.10.2023
PT09.10.2023
Former [2024/10]AT07.06.2023
CZ07.06.2023
EE07.06.2023
ES07.06.2023
FI07.06.2023
HR07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
PL07.06.2023
RO07.06.2023
RS07.06.2023
SE07.06.2023
SK07.06.2023
SM07.06.2023
NO07.09.2023
GR08.09.2023
IS07.10.2023
PT09.10.2023
Former [2024/09]AT07.06.2023
CZ07.06.2023
ES07.06.2023
FI07.06.2023
HR07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
RS07.06.2023
SE07.06.2023
SK07.06.2023
SM07.06.2023
NO07.09.2023
GR08.09.2023
IS07.10.2023
Former [2024/08]ES07.06.2023
FI07.06.2023
HR07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
RS07.06.2023
SE07.06.2023
SK07.06.2023
SM07.06.2023
NO07.09.2023
GR08.09.2023
Former [2024/03]ES07.06.2023
FI07.06.2023
HR07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
RS07.06.2023
SE07.06.2023
NO07.09.2023
GR08.09.2023
Former [2024/01]ES07.06.2023
HR07.06.2023
LT07.06.2023
LV07.06.2023
NL07.06.2023
RS07.06.2023
SE07.06.2023
NO07.09.2023
GR08.09.2023
Former [2023/52]ES07.06.2023
HR07.06.2023
NL07.06.2023
RS07.06.2023
SE07.06.2023
NO07.09.2023
GR08.09.2023
Former [2023/51]ES07.06.2023
HR07.06.2023
RS07.06.2023
SE07.06.2023
NO07.09.2023
GR08.09.2023
Former [2023/50]ES07.06.2023
SE07.06.2023
NO07.09.2023
GR08.09.2023
Former [2023/48]ES07.06.2023
SE07.06.2023
NO07.09.2023
Former [2023/46]ES07.06.2023
Documents cited:Search[X]WO2007032818  (ZOLTAN LAB LLC [US], et al) [X] 12-15 * paragraph [0004] - paragraph [0009]; example 32; claim 21; table 7 ** paragraph [0033] *;
 [A]  - RENTEA REBECCA M ET AL, "Radiation-induced changes in intestinal and tissue-nonspecific alkaline phosphatase: implications for recovery after radiation therapy", AMERICAN JOURNAL OF SURGERY, PAUL HOEBER, NEW YORK, NY, US, (20160718), vol. 212, no. 4, doi:10.1016/J.AMJSURG.2016.06.005, ISSN 0002-9610, pages 602 - 608, XP029761276 [A] 1-11 * abstract * * page 605; figures 1A-D *

DOI:   http://dx.doi.org/10.1016/j.amjsurg.2016.06.005
International search[Y]US2010158888  (KISS ZOLTAN [US]) [Y] 33-34* para [0086] *;
 [XY]US2011052560  (BRANDS RUDI [NL]) [X] 31 * Abstract; Claim 16; Claim 17; para [0008]; para [0026]; para [0058] * [Y] 1-9, 32-34;
 [Y]JP2017192381  (TOSOH CORP) [Y] 4, 9/4, 32 * para [0007]; para [0021]; SEQ ID NO:1 *;
 [Y]  - HAUER-JENSEN et al., "Radiation enteropathy--pathogenesis, treatment and prevention", Nat Rev Gastroenterol Hepatol., (20140800), vol. 11, no. 8, pages 470 - 479, XP055640559 [Y] 1-9 * . AOP, pp 1-10. (p1, col 2, last para-p2, col 1, para 1; p2, col 1, box 1; p2, col 2, para 3; p8, col 2, box *

DOI:   http://dx.doi.org/10.1038/nrgastro.2014.46
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.