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Extract from the Register of European Patents

EP About this file: EP3783016

EP3783016 - MODIFIED ANTIBODY AND RADIOACTIVE METAL-LABELLED ANTIBODY [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  22.01.2021
Database last updated on 03.10.2024
FormerThe international publication has been made
Status updated on  25.10.2019
Most recent event   Tooltip27.04.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Nihon Medi-Physics Co., Ltd
3-4-10, Shinsuna
Koto-ku
Tokyo, 136-0075 / JP
For all designated states
National University Corporation Kagoshima University
21-24, Korimoto 1-chome
Kagoshima-shi
Kagoshima 890-8580 / JP
For all designated states
National University Corporation Chiba University
1-33, Yayoi-cho
Inage-ku
Chiba-shi, Chiba 263-8522 / JP
[2021/08]
Inventor(s)01 / KOMOTO Shota
c/o NIHON MEDI-PHYSICS CO., LTD., 3-4-10,
Shinsuna, Koto-ku
Tokyo 136-0075 / JP
02 / OGAWA Yu
c/o NIHON MEDI-PHYSICS CO., LTD., 3-4-10,
Shinsuna, Koto-ku
Tokyo 136-0075 / JP
03 / SHOYAMA Yoshinari
c/o NIHON MEDI-PHYSICS CO., LTD., 3-4-10,
Shinsuna, Koto-ku
Tokyo 136-0075 / JP
04 / HATANO Tadashi
c/o NIHON MEDI-PHYSICS CO., LTD., 3-4-10,
Shinsuna, Koto-ku
Tokyo 136-0075 / JP
05 / ITO Yuji
c/o National University Corporation Kagoshima
University, 21-24, Korimoto 1-chome
Kagoshima-shi, Kagoshima 890-8580 / JP
06 / ARANO Yasushi
c/o Graduate School and Faculty of Pharmaceutical
Sciences, Chiba University, 1-8-1, Inohana, Chuo-
ku
Chiba-shi, Chiba 260-0856 / JP
07 / SUZUKI Hiroyuki
c/o Graduate School and Faculty of Pharmaceutical
Sciences, Chiba University, 1-8-1, Inohana, Chuo-
ku
Chiba-shi, Chiba 260-0856 / JP
08 / UEHARA Tomoya
c/o Graduate School and Faculty of Pharmaceutical
Sciences, Chiba University, 1-8-1, Inohana, Chuo-
ku
Chiba-shi, Chiba 260-0856 / JP
 [2021/08]
Representative(s)TBK
Bavariaring 4-6
80336 München / DE
[2021/08]
Application number, filing date19787597.415.04.2019
[2021/08]
WO2019JP16156
Priority number, dateJP2018007848716.04.2018         Original published format: JP 2018078487
[2021/08]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2019203191
Date:24.10.2019
Language:JA
[2019/43]
Type: A1 Application with search report 
No.:EP3783016
Date:24.02.2021
Language:EN
[2021/08]
Search report(s)International search report - published on:JP24.10.2019
(Supplementary) European search report - dispatched on:EP19.05.2021
ClassificationIPC:A61K51/10, A61K51/08, C07K16/00, A61K39/395, A61K47/68, A61K47/69, C07D257/02, C07K7/06, C07K7/08, C07K19/00, C07K14/00, C07K16/32
[2021/24]
CPC:
A61K51/081 (EP,KR); C07K7/08 (EP,KR,US); A61K51/1093 (EP,KR,US);
A61K39/395 (EP); A61K47/6887 (US); A61K47/6889 (US);
A61K51/0482 (US); A61K51/088 (EP,KR,US); A61K51/1051 (EP);
A61K51/1096 (US); C07D257/02 (US); C07K14/001 (EP,KR);
C07K16/32 (EP,KR,US); C07K5/06078 (US); C07K5/0812 (US);
A61K2039/505 (KR); C07K2317/21 (US); C07K2317/24 (EP,KR) (-)
C-Set:
A61K39/395, A61K2300/00 (EP)
Former IPC [2021/08]C07K16/00, A61K39/395, A61K47/68, A61K47/69, A61K51/10, C07D257/02, C07K7/06, C07K7/08, C07K19/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/08]
TitleGerman:MODIFIZIERTER ANTIKÖRPER UND RADIOAKTIV MARKIERTER ANTIKÖRPER[2021/08]
English:MODIFIED ANTIBODY AND RADIOACTIVE METAL-LABELLED ANTIBODY[2021/08]
French:ANTICORPS MODIFIÉ ET ANTICORPS MARQUÉ PAR UN MÉTAL RADIOACTIF[2021/08]
Entry into regional phase21.10.2020Translation filed 
21.10.2020National basic fee paid 
21.10.2020Search fee paid 
21.10.2020Designation fee(s) paid 
21.10.2020Examination fee paid 
Examination procedure21.10.2020Examination requested  [2021/08]
16.12.2021Amendment by applicant (claims and/or description)
Fees paidRenewal fee
27.04.2021Renewal fee patent year 03
30.03.2022Renewal fee patent year 04
29.03.2023Renewal fee patent year 05
25.04.2024Renewal fee patent year 06
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[IDA]WO2017217347  (UNIV KAGOSHIMA [JP]) [ID] 8,9 * examples 8,10 * [A] 1-7,10-12;
 [XP]WO2019065774  (UNIV CHIBA NAT UNIV CORP [JP]) [XP] 10,11 * compound b31 * * paragraph [0141] * * paragraph [0145] *;
 EP3470418  [ ] (UNIV KAGOSHIMA [JP]) [ ] * examples 8,10 *;
 EP3689892  [ ] (UNIV CHIBA NAT UNIV CORP [JP]) [ ] * compound b31 * * paragraph [0252] ** paragraph [0256] *
International search[A]JP2015086213  (UNIV CHIBA) [A] 1-7, 10-12 * , *;
 [A]JP2017518975  [A] 5-7;
 [A]WO2017217347  (UNIV KAGOSHIMA [JP]) [A] 1-12 * , *;
 [PX]WO2019065774  (UNIV CHIBA NAT UNIV CORP [JP]) [PX] 10-12* , [0113], *;
 [A]  - Misato Uchimura , "A new DOTA derivative providing &(Ga-labeled probes of high in vivo stability", 138th Annual Meeting of the Pharmaceutical Society of Japan, (20180325), vol. 138, pages 1 - 1, XP009523930 [A] 1-7, 10-12
by applicantWO2013081091
 WO2016186206
 WO2017150549
 WO2017217347
 WO2017217437
 JP2018078487
    - RODWELL, J. D. et al., Proceedings of the National Academy of Sciences of the United States of America, (19860000), vol. 83, pages 2632 - 2636
    - AXUP, J. Y. et al., Proceedings of the National Academy of Sciences of the United States of America, (20120000), vol. 109, pages 16101 - 16106
    - TIAN, F. et al., Proceedings of the National Academy of Sciences of the United States of America, (20140000), vol. 111, pages 1766 - 1771
    - ZIMMERMAN, E. S. et al., Bioconjugate chemistry, (20140000), vol. 25, pages 351 - 361
    - SHEN, B. Q. et al., Nature biotechnology, (20120000), vol. 30, pages 184 - 189
    - BERNARDES, G. J. et al., Nature protocols, (20130000), vol. 8, pages 2079 - 2089
    - ARANO, YASUSHI et al., "Chemical design of radiolabeled antibody fragments for low renal radioactivity levels", Cancer research, (19990000), vol. 59, no. 1, pages 128 - 134, XP000982261
    - UEHARA, TOMOYA et al., "Design, synthesis, and evaluation of [188Re] organorhenium-labeled antibody fragments with renal enzyme-cleavable linkage for low renal radioactivity levels", Bioconjugate chemistry, (20070000), vol. 18, no. 1, doi:10.1021/bc0602329, pages 190 - 198, XP055623938

DOI:   http://dx.doi.org/10.1021/bc0602329
    - KELLEY et al., Genetics Engineering Principles and Methods, Plenum Press, (19900000), vol. 12, pages 1 - 19
    - "Solid-Phase Peptide Synthesis", STEWART et al., Proc. Natl. Acad. Sci. USA, W.H. Freeman Co., (19850000), vol. 82, page 5132
    - Journal of Medicinal Chemistry, (19970000), vol. 40, pages 2643 - 2652
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.