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Extract from the Register of European Patents

EP About this file: EP3781019

EP3781019 - FLUORINE-18 LABELED COMPOSITIONS AND THEIR USE IN IMAGING OF BIOLOGICAL TISSUE [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  22.01.2021
Database last updated on 11.09.2024
FormerThe international publication has been made
Status updated on  25.10.2019
Most recent event   Tooltip24.07.2024Change - representative 
Applicant(s)For all designated states
Cornell University
Center for Technology Licensing at
Cornell University (CTL)
395 Pine Tree Road
Suite 310
Ithaca, New York 14850 / US
For all designated states
Memorial Sloan-Kettering Cancer Center
1275 York Avenue
New York, NY 10065 / US
[2021/08]
Inventor(s)01 / TING, Richard
Center for Technology Licensing at Cornell
University (CTL) 395 Pine Tree Road Suite 310
Ithaca
New York 14850 / US
02 / ARAS, Omer
c/o Memorial Sloan Kettering Cancer Center 1275
York Avenue
New York, NY 10065 / US
03 / WANG, Ye
Center for Technology Licensing at Cornell
University (CTL) 395 Pine Tree Road Suite 310
Ithaca
New York 14850 / US
04 / HARIKRISHNA, Kommiddi
Center for Technology Licensing at Cornell
University (CTL) 395 Pine Tree Road Suite 310
Ithaca
New York 14850 / US
05 / GUO, Hua
Center for Technology Licensing at Cornell
University (CTL) 395 Pine Tree Road Suite 310
Ithaca
New York 14850 / US
06 / AN, Feifei
Center for Technology Licensing at Cornell
University (CTL) 395 Pine Tree Road Suite 310
Ithaca
New York 14850 / US
07 / CHEN, Nandi
Center for Technology Licensing at Cornell
University (CTL) 395 Pine Tree Road Suite 310
Ithaca
New York 14850 / US
 [2021/08]
Representative(s)Reddie & Grose LLP
The White Chapel Building
10 Whitechapel High Street
London E1 8QS / GB
[N/P]
Former [2021/08]Roberts, Michael Austin
Reddie & Grose LLP The White Chapel Building
10 Whitechapel High Street
London E1 8QS / GB
Application number, filing date19788273.117.04.2019
[2021/08]
WO2019US27864
Priority number, dateUS201862658880P17.04.2018         Original published format: US 201862658880 P
[2021/08]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2019204432
Date:24.10.2019
Language:EN
[2019/43]
Type: A2 Application without search report 
No.:EP3781019
Date:24.02.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 24.10.2019 takes the place of the publication of the European patent application.
[2021/08]
Search report(s)International search report - published on:US12.12.2019
(Supplementary) European search report - dispatched on:EP15.03.2022
ClassificationIPC:A61K49/00, A61K51/04, A61K51/12, A61K101/02, A61B5/00, A61B6/03, A61B6/00, A61B8/13, G01N23/046
[2022/15]
CPC:
A61K49/0097 (EP); A61K51/1203 (EP,US); A61B5/0071 (EP);
A61B6/037 (EP); A61B6/4417 (EP); A61B6/481 (EP);
A61B6/508 (EP); A61K49/0002 (EP); A61K49/0021 (EP);
A61K49/0032 (EP,US); A61K49/0043 (EP,US); A61K49/0052 (EP);
A61K51/04 (EP); A61K51/0402 (EP); A61K51/0421 (EP);
A61K51/0453 (EP); A61K51/0497 (EP) (-)
Former IPC [2021/08]A61B5/00, A61B8/13, G01N23/046
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/08]
TitleGerman:FLUOR-18-MARKIERTE ZUSAMMENSETZUNGEN UND IHRE VERWENDUNG ZUR ABBILDUNG VON BIOLOGISCHEM GEWEBE[2021/08]
English:FLUORINE-18 LABELED COMPOSITIONS AND THEIR USE IN IMAGING OF BIOLOGICAL TISSUE[2021/08]
French:COMPOSITIONS MARQUÉES AU FLUOR -18 ET LEUR UTILISATION EN IMAGERIE DE TISSUS BIOLOGIQUES[2021/08]
Entry into regional phase21.10.2020National basic fee paid 
21.10.2020Search fee paid 
21.10.2020Designation fee(s) paid 
21.10.2020Examination fee paid 
Examination procedure21.10.2020Examination requested  [2021/08]
28.09.2022Amendment by applicant (claims and/or description)
Fees paidRenewal fee
27.04.2021Renewal fee patent year 03
27.04.2022Renewal fee patent year 04
27.04.2023Renewal fee patent year 05
29.04.2024Renewal fee patent year 06
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Documents cited:Search[E]WO2019226962  (UNIV CORNELL [US], et al) [E] 1,3,5,6,9-11,17 * paragraph [0089] * * figure 12 * * examples 1-4 * * paragraph [0083] *;
 [XP]  - HARIKRISHNA KOMMIDI ET AL, "18 F-Positron Emitting/Trimethine Cyanine-Fluorescent Contrast for Image-Guided Prostate Cancer Management", JOURNAL OF MEDICINAL CHEMISTRY, US, (20180420), vol. 61, no. 9, doi:10.1021/acs.jmedchem.8b00240, ISSN 0022-2623, pages 4256 - 4262, XP055580239 [XP] 1-3,5,9-17 * abstract * * page 4259, column 2, paragraph 5 - page 4260, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1021/acs.jmedchem.8b00240
 [XI]  - KOMMIDI HARIKRISHNA ET AL, "An [ 18 F]-Positron-Emitting, Fluorescent, Cerebrospinal Fluid Probe for Imaging Damage to the Brain and Spine", THERANOSTICS, AU, (20170101), vol. 7, no. 9, doi:10.7150/thno.19408, ISSN 1838-7640, pages 2377 - 2391, XP055896937 [X] 1,3,9,10,18 * abstract * * scheme 1 * * page 2386, column 2, paragraph 3 * [I] 4

DOI:   http://dx.doi.org/10.7150/thno.19408
 [XI]  - WANG YE ET AL, "18 F-positron-emitting/fluorescent labeled erythrocytes allow imaging of internal hemorrhage in a murine intracranial hemorrhage model", JOURNAL OF CEREBRAL BLOOD FLOW & METABOLISM, US, vol. 37, no. 3, doi:10.1177/0271678X16682510, ISSN 0271-678X, (20170301), pages 776 - 786, URL: http://journals.sagepub.com/doi/full-xml/10.1177/0271678X16682510, (20220302), XP055896944 [X] 1-3,6-10 * abstract * * figures 1-3 * [I] 4

DOI:   http://dx.doi.org/10.1177/0271678X16682510
 [X]  - LIU SHUANGLONG ET AL, "Efficient synthesis of fluorescent-PET probes based on [18F]BODIPY dye", CHEMICAL COMMUNICATIONS, UK, (20140101), vol. 50, no. 55, doi:10.1039/c4cc01411a, ISSN 1359-7345, page 7371, XP055896953 [X] 1-3,5,9,10 * abstract * * Schemes 1-2 * * table 1 * * figure 1 * * page 7372, column 2, paragraph 2 - page 7373, column 1, paragraph 1 *

DOI:   http://dx.doi.org/10.1039/c4cc01411a
 [X]  - RODRIGUEZ ERIK A. ET AL, "New Dioxaborolane Chemistry Enables [ 18 F]-Positron-Emitting, Fluorescent [ 18 F]-Multimodality Biomolecule Generation from the Solid Phase", BIOCONJUGATE CHEMISTRY, US, (20160518), vol. 27, no. 5, doi:10.1021/acs.bioconjchem.6b00164, ISSN 1043-1802, pages 1390 - 1399, XP055897006 [X] 1-3,5,9-12 * abstract * * figure 1 * * page 1396, column 1, paragraph 4 *

DOI:   http://dx.doi.org/10.1021/acs.bioconjchem.6b00164
International search[A]US6201989  (WHITEHEAD PETER D [CA], et al) [A] 1-5, 11-13, 15-17, 21, 22* ENTIRE DOCUMENT *;
 [A]US2006134001  (FRANGIONI JOHN V [US]) [A] 1-5, 11-13, 15-17, 21, 22 * ENTIRE DOCUMENT *;
 [Y]US2007178511  (LEUNG WAI-YEE [US], et al) [Y] 2, 11-13 * (02.08.20070 para [0045];[0052];[0053] *;
 [XY]  - AN et al., "A Conjugate of Pentamethine Cyanine and 18F as a Positron Emission Tomography/Near-Infrared Fluorescence Probe for Multimodality Tumor Imaging", International Journal of Molecular Sciences, (20170607), vol. 18, no. 1214, pages 1 - 11, XP055661037 [X] 1, 3, 4, 15-17, 21, 22 * Abstract; pg 2, para 4, figure 1;pg. 6, para 2, Figure 8 * [Y] 2, 5, 11-13

DOI:   http://dx.doi.org/10.3390/ijms18061214
 [Y]  - GRABNER et al., "PET with 18F-FDG-Labeled T Lymphocytes for Diagnosis of Acute Rat Renal Allograft Rejection", Journal of Nuclear Medicine, (20130513), vol. 54, no. 7, pages 1147 - 1153, XP055661040 [Y] 5 * . abstract *

DOI:   http://dx.doi.org/10.2967/jnumed.112.109231
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