EP3793982 - SMALL MOLECULE INHIBITORS OF THE NUCLEAR TRANSLOCATION OF ANDROGEN RECEPTOR FOR THE TREATMENT OF CASTRATION-RESISTANT PROSTATE CANCER [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 24.03.2023 Database last updated on 03.09.2024 | |
Former | Request for examination was made Status updated on 19.02.2021 | ||
Former | The international publication has been made Status updated on 22.11.2019 | Most recent event Tooltip | 24.03.2023 | Application deemed to be withdrawn | published on 26.04.2023 [2023/17] | Applicant(s) | For all designated states University of Pittsburgh - of the Commonwealth System of Higher Education 1st Floor Gardner Steel Conference Center 130 Thackeray Avenue Pittsburgh, Pennsylvania 15260 / US | [2021/12] | Inventor(s) | 01 /
MILLIGAN, John Department of Chemistry Chevron Science Center ( 1301 CHVRN) 219 Parkman Avenue Pittsburgh, Pennsylvania 15260 / US | 02 /
TAI, Serene Department of Chemistry Chevron Science Center ( 650 CHVRN) 219 Parkman Ave. Pittsburgh, Pennsylvania 15260 / US | 03 /
NELSON, Joel B. UPMC 200 Lothrop St. Pittsburgh, Pennsylvania 15213-2582 / US | 04 /
JOHNSON, James K. University of Pittsburgh Department of Chemistry Chevron Science Center (650 CHVRN) 219 Parkman Avenue Pittsburgh, Pennsylvania 15260 / US | 05 /
SKODA, Erin M. 1203 Fidler Ln, 413 Silver Spring, Maryland 20910 / US | 06 /
WANG, Zhou Shadyside Medical Center, Suite G40 5200 Centre Ave. Pittsburgh, Pennsylvania 15232 / US | 07 /
TAKUBO, Keita Department of Chemistry Chevron Science Center ( 650 CHVRN) 219 Parkman Avenue Pittsburgh, Pennsylvania 15260 / US | 08 /
WIPF, Peter Department of Chemistry Chevron Science Center ( 1301 CHVRN) 219 Parkman Avenue Pittsburgh, Pennsylvania 15260 / US | [2021/12] | Representative(s) | HGF HGF Limited 1 City Walk Leeds LS11 9DX / GB | [N/P] |
Former [2021/12] | HGF 1 City Walk Leeds LS11 9DX / GB | Application number, filing date | 19803487.8 | 13.05.2019 | [2021/12] | WO2019US32033 | Priority number, date | US201862671254P | 14.05.2018 Original published format: US 201862671254 P | [2021/12] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2019222105 | Date: | 21.11.2019 | Language: | EN | [2019/47] | Type: | A1 Application with search report | No.: | EP3793982 | Date: | 24.03.2021 | Language: | EN | The application published by WIPO in one of the EPO official languages on 21.11.2019 takes the place of the publication of the European patent application. | [2021/12] | Search report(s) | International search report - published on: | IL | 21.11.2019 | (Supplementary) European search report - dispatched on: | EP | 12.04.2022 | Classification | IPC: | C07D295/185, C07D209/52, C07C49/563, C07D409/02, C07D207/06, C07D207/08, C07D233/61, C07D487/04, A61K31/12, A61K31/165, A61K31/40, A61K31/403, A61K31/407, A61K31/495, A61K31/496, A61K31/498, A61P35/00 | [2021/12] | CPC: |
A61K31/403 (EP);
A61K31/4166 (EP);
A61K31/495 (EP);
A61K31/58 (EP);
A61P35/00 (EP);
C07D209/52 (EP);
C07D239/42 (EP);
C07D295/185 (EP);
C07D309/14 (EP);
C07D333/24 (EP)
(-)
| C-Set: |
A61K31/403, A61K2300/00 (EP);
A61K31/4166, A61K2300/00 (EP);
A61K31/495, A61K2300/00 (EP);
A61K31/58, A61K2300/00 (EP) | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2021/12] | Title | German: | KLEINMOLEKÜLIGE INHIBITOREN DER NUKLEAREN TRANSLOKATION DES ANDROGENREZEPTORS ZUR BEHANDLUNG VON KASTRATIONSRESISTENTEM PROSTATAKREBS | [2021/12] | English: | SMALL MOLECULE INHIBITORS OF THE NUCLEAR TRANSLOCATION OF ANDROGEN RECEPTOR FOR THE TREATMENT OF CASTRATION-RESISTANT PROSTATE CANCER | [2021/12] | French: | INHIBITEURS À PETITES MOLÉCULES DE LA TRANSLOCATION NUCLÉAIRE DU RÉCEPTEUR DES ANDROGÈNES POUR TRAITER LE CANCER DE LA PROSTATE RÉSISTANT À LA CASTRATION | [2021/12] | Entry into regional phase | 09.12.2020 | National basic fee paid | 09.12.2020 | Search fee paid | 09.12.2020 | Designation fee(s) paid | 09.12.2020 | Examination fee paid | Examination procedure | 09.12.2020 | Amendment by applicant (claims and/or description) | 09.12.2020 | Examination requested [2021/12] | 15.11.2022 | Application deemed to be withdrawn, date of legal effect [2023/17] | 08.12.2022 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2023/17] | Fees paid | Renewal fee | 13.05.2021 | Renewal fee patent year 03 | 28.04.2022 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [Y]WO2017165822 (UNIV OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US], et al) [Y] 1-15 * pages 12,26-30; claim 1 *; | [Y] - PAOLA CIAPETTI AND BRUNO GIETHLEN ED - CAMILLE GEORGES WERMUTH, Chapter 15 - Molecular Variations Based on Isosteric Replacements, THE PRACTICE OF MEDICINAL CHEMISTRY (THIRD EDITION), ELSEVIER, NL, PAGE(S) 290 - 342, (20080101), ISBN 978-0-12-374194-3, XP009142466 [Y] 1-15 * page 294, section III.B, table 15.8 * DOI: http://dx.doi.org/10.1016/B978-0-12-374194-3.00015-9 | International search | [X]WO2017165822 (UNIV OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION [US], et al) [X] 1-16 * The whole document. Especially: abstract, page 1, claims 1, 9, 15-21 and 25, Figs. 2H and 21. *; | [XP]US2019022093 (WIPF PETER [US], et al) [XP] 1-16* The whole document. Especially: claims 9, 15 and Fig. 2J. * | [X] - "CA Index Name: 1-Piperazineacetic acid, alpha-(2- chlorophenyl)-4-[[2-[2-(trifluoromethyl)phenyl]cyclopropy1]carbonyl]- , methyl ester", Registry, (20180301), Database accession no. RN 2180239-98-7, URL: STN [X] 1-3 | [X] - "CA Index Name: 1-Piperazineacetic acid, alpha-(2- chlorophenyl)-4-[[2-(2-chlorophenyl)cyclopropyl]carbonyl]- , methyl ester", Registry, (20110811), Database accession no. RN- 1316002-05-7, URL: STN [X] 1, 2 | [ ] - PubChem, (20120125), Database accession no. 55492389 | [ ] - "Source: AKos Consulting & Solutions", PubChem, (20110811), Database accession no. 132985172 | [X] - "CA Index Name: Methanone, [4-[1-(2-chlorophenyl) ethyl]-1-piperazinyl][2-(2-fluorophenyl)cyclopropyl", Registry, (20110512), Database accession no. RN 1293729-94-8, URL: STN [X] 1-3, 5, 6 | [ ] - PubChem, (20120125), Database accession no. 55564470 | [ ] - "AKos Consulting & Solutions", PubChem, (20110512), Database accession no. 33095776 | [X] - "CA Index Name: 1-Piperazineacetic acid, alpha-(4- chlorophenyl)-4-[[2-(3,4-difluorophenyl)cyclopropyl]carbonyl]-, methyl ester", Registry, (20140919), Database accession no. RN 1623249-86-4, URL: STN [X] 1-4 | [ ] - PubChem, (20150207), Database accession no. 86903336 | [ ] - "Aurora Fine Chemicals LLC", PubChem, (20160113), Database accession no. 280705617 |