blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP3876964

EP3876964 - COMPOSITIONS COMPRISING PARABACTEROIDES BACTERIAL STRAINS FOR TREATING CANCER [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  28.04.2023
Database last updated on 14.09.2024
FormerExamination is in progress
Status updated on  12.11.2021
FormerRequest for examination was made
Status updated on  13.08.2021
FormerThe international publication has been made
Status updated on  20.06.2020
Formerunknown
Status updated on  11.01.2020
Most recent event   Tooltip23.06.2023Interruptionpublished on 26.07.2023  [2023/30]
Applicant(s)For all designated states
4D Pharma Research Limited
Life Sciences Innovation Building
Cornhill Road
Aberdeen, Aberdeenshire AB25 2ZS / GB
[2021/37]
Inventor(s)01 / MULDER, Imke Elisabeth
c/o 4D Pharma Research Limited Life Sciences
Innovation Building Cornhill Road
Aberdeen Aberdeenshire AB25 2ZS / GB
02 / ETTORRE, Anna
c/o 4D Pharma Research Limited Life Sciences
Innovation Building Cornhill Road
Aberdeen Aberdeenshire AB25 2ZS / GB
03 / AHMED, Suaad
c/o 4D Pharma Research Limited Life Sciences
Innovation Building Cornhill Road
Aberdeen Aberdeenshire AB25 2ZS / GB
04 / FOTIADOU, Parthena
c/o 4D Pharma Research Limited Life Sciences
Innovation Building Cornhill Road
Aberdeen Aberdeenshire AB25 2ZS / GB
 [2021/37]
Representative(s)(deleted)
[N/P]
Former [2021/37]Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
Application number, filing date19829463.912.12.2019
[2021/37]
WO2019EP84994
Priority number, dateEP2018021208712.12.2018         Original published format: EP 18212087
GB2019001600104.11.2019         Original published format: GB 201916001
WO2019EP8013104.11.2019         Original published format: PCT/EP2019/080131
[2021/37]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020120717
Date:18.06.2020
Language:EN
[2020/25]
Type: A1 Application with search report 
No.:EP3876964
Date:15.09.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 18.06.2020 takes the place of the publication of the European patent application.
[2021/37]
Search report(s)International search report - published on:EP18.06.2020
ClassificationIPC:A61K35/74, A61P35/00, A61K39/00
[2021/37]
CPC:
A61K35/741 (EP,IL,KR); A61K35/74 (US); A61K31/706 (KR);
A61P35/00 (EP,IL,KR); A61K2035/115 (EP,IL,KR); A61K2039/55511 (EP,IL);
Y02A50/30 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/37]
Extension statesBA10.06.2021
ME10.06.2021
Validation statesMA10.06.2021
MD10.06.2021
TitleGerman:ZUSAMMENSETZUNGEN MIT PARABACTEROIDEN BAKTERIENSTÄMMEN ZUR BEHANDLUNG VON KREBS[2021/37]
English:COMPOSITIONS COMPRISING PARABACTEROIDES BACTERIAL STRAINS FOR TREATING CANCER[2021/37]
French:COMPOSITIONS COMPRENANT DES SOUCHES BACTÉRIENNES PARABACTEROIDES POUR LE TRAITEMENT DU CANCER[2021/37]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase10.06.2021National basic fee paid 
10.06.2021Designation fee(s) paid 
10.06.2021Examination fee paid 
Examination procedure17.07.2020Request for preliminary examination filed
International Preliminary Examining Authority: EP
10.06.2021Amendment by applicant (claims and/or description)
10.06.2021Examination requested  [2021/37]
10.06.2021Date on which the examining division has become responsible
11.11.2021Despatch of a communication from the examining division (Time limit: M04)
21.03.2022Reply to a communication from the examining division
21.06.2022Despatch of a communication from the examining division (Time limit: M06)
03.01.2023Application deemed to be withdrawn, date of legal effect  [2023/22]
24.01.2023Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2023/22]
Fees paidRenewal fee
30.11.2021Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.12.202204   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Stay/Interruption17.03.2023Interruption of proceedings. Reason: legal prevention of applicant[2023/30]
Cited inInternational search[YD]WO2016149449  (UNIV TUFTS [US]) [YD] 1-21 * claims 1, 2 *;
 [AD]WO2016203220  (4D PHARMA RES LTD [GB]) [AD] 1-21 * page 1 - page 5 *;
 [XY]WO2018094190  (SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST [US], et al) [X] 1,2,4-17 * page 1, line 20 - page 8, line 12; claims 26-28 * [Y] 1-27;
 [ID]WO2018112365  (EVELO BIOSCIENCES INC [US]) [ID] 1-21 * examples 1-3 * * claims 1-3 *;
 [Y]WO2018112363  (EVELO BIOSCIENCES INC [US]) [Y] 1-21 * claims 1, 2 *;
 [I]  - GAR YEE KOH ET AL, "Parabacteroides distasonis attenuates toll-like receptor 4 signaling and Akt activation and blocks colon tumor formation in high-fat diet-fed azoxymethane-treated mice : Parabacteroides distasonis and colon tumorigenesis", INTERNATIONAL JOURNAL OF CANCER, US, (20180903), vol. 143, no. 7, doi:10.1002/ijc.31559, ISSN 0020-7136, pages 1797 - 1805, XP055576356 [I] 1-15 *Discussion*

DOI:   http://dx.doi.org/10.1002/ijc.31559
 [Y]  - DANKNER MATTHEW ET AL, "Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations", ONCOGENE, NATURE PUBLISHING GROUP UK, LONDON, vol. 37, no. 24, doi:10.1038/S41388-018-0171-X, ISSN 0950-9232, (20180315), pages 3183 - 3199, (20180315), XP036604861 [Y] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1038/s41388-018-0171-x
 [Y]  - JHEN-WEI RUAN ET AL, "Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice", NATURE MICROBIOLOGY, (20161128), vol. 2, no. 2, doi:10.1038/nmicrobiol.2016.220, pages 1 - 12, XP055580771 [Y] 3 * page 1, column l *

DOI:   http://dx.doi.org/10.1038/nmicrobiol.2016.220
 [Y]  - NEERAJ LAL ET AL, "KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer", CLINICAL CANCER RESEARCH, US, (20171023), vol. 24, no. 1, doi:10.1158/1078-0432.CCR-17-1090, ISSN 1078-0432, pages 224 - 233, XP055673689 [Y] 22-27 * abstract * *Discussion*

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-17-1090
by applicantWO03046580
 WO2013008039
 WO2013050792
 WO2014167338
 WO2016149449
 WO2016203220
 WO2018094190
 WO2018112365
 WO2018112363
    - "UniProt", Database accession no. P15056
    - SPOR et al., Nat Rev Microbiol., (20110000), vol. 9, no. 4, pages 279 - 90
    - ECKBURG et al., Science, (20050000), vol. 308, no. 5728, pages 1635 - 8
    - MACPHERSON et al., Microbes Infect., (20010000), vol. 3, no. 12, pages 1021 - 35
    - MACPHERSON et al., Cell Mol Life Sci., (20020000), vol. 59, no. 12, pages 2088 - 96
    - MAZMANIAN et al., Cell, (20050000), vol. 122, no. 1, pages 107 - 18
    - FRANK et al., PNAS, (20070000), vol. 104, no. 34, pages 13780 - 5
    - SCANLAN et al., J Clin Microbiol., (20060000), vol. 44, no. 11, pages 3980 - 8
    - KANG et al., Inflamm Bowel Dis., (20100000), vol. 16, no. 12, pages 2034 - 42
    - MACHIELS et al., Gut, (20130000), vol. 63, no. 8, pages 1275 - 83
    - GOLDINGORBACH, Clin Infect Dis., (20080000), vol. 46, no. 2, pages 96 - 100
    - AZAD et al., BMJ, (20130000), vol. 347, page f6471
    - KOH et al., International Journal of Cancer, vol. 143, no. 7, pages 1797 - 1805
    - WU et al., Gut
    - SAKAMOTOBENNO, Int J Syst Evol Microbiol., (20060000), vol. 56, pages 1599 - 605
    - MASCO et al., Systematic and Applied Microbiology, (20030000), vol. 26, pages 557 - 563
    - SRUTKOVA et al., J. Microbiol. Methods, (20110000), vol. 87, no. 1, pages 10 - 6
    - LIU et al., Acta Pharmaceutica Sinica B, (20180000), vol. 8, no. 4, pages 552 - 562
    - KUBICABREWER, Mayo ClinProc, (20120000), vol. 87, no. 1, pages 991 - 1003
    - VIGUER et al., J Immunol, (20040000), vol. 173, pages 1444 - 1453
    - MCCARTER et al., Ann Surg Oncol., (20070000), vol. 14, no. 10, pages 2854 - 60
    - DANKNER et al., Oncogene, (20180000), vol. 37, pages 3183 - 3199
    - JONES et al., J Clin Oncol., (20170810), vol. 35, no. 23, pages 2624 - 2630
    - ASCIERTO et al., Journal of Translational Medicine, (20120000), vol. 10, page 85
    - SOLTANI MH et al., Am J Pathol, (20050000), vol. 166, pages 1841 - 50
    - XIE, Med Res Rev, (20160000), vol. 36, no. 2, pages 300 - 312
    - SHI et al., Cancer Discov, (20140000), vol. 4, pages 80 - 93
    - MIYAMOTO-SHINOHARA et al., J. Gen. Appl. Microbiol., (20080000), vol. 54, pages 9 - 24
    - LESLIE et al., Appl. Environ. Microbiol., (19950000), vol. 61, pages 3592 - 3597
    - MITROPOULOU et al., J Nutr Metab., (20130000), vol. 716861
    - KAILASAPATHY et al., Curr Issues Intest Microbiol., (20020000), vol. 3, no. 2, pages 39 - 48
    - STROBEL, Methods Mol Biol., (20090000), vol. 581, pages 247 - 61
    - Handbook of Experimental Immunology, Blackwell Scientific Publications, (19860000), vol. I-IV
    - LIVAKSCHMITTGEN, Methods, (20010000), vol. 25, no. 4, pages 402 - 8
    - SMITHWATERMAN, Adv. Appl. Math., (19810000), vol. 2, pages 482 - 489
    - THANGARAJU et al., Cancer Res., (20090000), vol. 67, no. 9, pages 2826 - 2832
    - QIN et al., Oncol Res., (20110000), vol. 19, no. 12, pages 573 - 582
    - BRONTE et al., Immunity, (20130000), vol. 39, no. 5, pages 806 - 818
    - BERRAONDO, British Journal of Cancer, (20190000), vol. 120, pages 6 - 15
    - YAN et al., Immunotherapy, (20170000), vol. 9, no. 4, pages 347 - 360
    - NILU, Cancer Med., (20180000), vol. 7, no. 9, pages 4509 - 4516
    - FABBI et al., Mediators of Inflammation, (20170000), pages 1 - 14
    - ABEL et al., Front. Immunol., (20180000), vol. 9, page 1869
    - MORVANLANIER, Nature Reviews Cancer, (20160000), vol. 16, pages 7 - 19
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.