Extract from the Register of European Patents

EP About this file: EP3894557

EP3894557 - COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING AMYOTROPHIC LATERAL SCLEROSIS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  19.05.2023
Database last updated on 08.04.2026
FormerRequest for examination was made
Status updated on  17.09.2021
FormerThe international publication has been made
Status updated on  20.06.2020
Formerunknown
Status updated on  23.01.2020
Most recent event   Tooltip18.12.2025New entry: Renewal fee paid 
Applicant(s)For all designated states
Biogen MA Inc.
225 Binney Street
Cambridge, MA 02142 / US
[2024/44]
Former [2021/42]For all designated states
Biogen MA Inc.
225 Binney Street
Cambridge, MA 02142 / US
For all designated states
Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010 / US
Inventor(s)01 / NESTOROV, Ivan Alexandrov
Biogen MA Inc.
225 Binney Street
Cambridge, Massachusetts 02142 / US
02 / FERGUSON, Toby
Biogen MA Inc.
225 Binney Street
Cambridge, Massachusetts 02142 / US
03 / NORRIS, Daniel A.
Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, California 92010 / US
 [2021/42]
Representative(s)Carpmaels & Ransford LLP
One Southampton Row
London WC1B 5HA / GB
[2021/42]
Application number, filing date19836331.912.12.2019
[2021/42]
WO2019US65936
Priority number, dateUS201862779916P14.12.2018         Original published format: US 201862779916 P
US201962807603P19.02.2019         Original published format: US 201962807603 P
US201962840879P30.04.2019         Original published format: US 201962840879 P
[2021/42]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020123783
Date:18.06.2020
Language:EN
[2020/25]
Type: A1 Application with search report 
No.:EP3894557
Date:20.10.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 18.06.2020 takes the place of the publication of the European patent application.
[2021/42]
Search report(s)International search report - published on:EP18.06.2020
ClassificationIPC:C12N15/113, A61P25/14
[2021/42]
CPC:
C12N15/1137 (EP,CN,IL,KR,US); A61K31/7088 (CN); A61K31/7105 (KR);
A61P21/00 (CN); A61P25/00 (CN); A61P25/28 (KR);
C12N9/0089 (KR); C12Y115/01001 (KR,US); C12N2310/11 (EP,CN,IL,KR,US);
C12N2310/315 (EP,IL,US); C12N2310/321 (IL,KR,US); C12N2310/322 (KR);
C12N2310/3341 (EP,IL,KR,US); C12N2310/3525 (IL,KR,US); C12N2320/32 (CN);
C12N2320/35 (EP,IL,KR,US) (-)
C-Set:
C12N2310/321, C12N2310/3525 (EP)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/42]
Extension statesBA06.07.2021
ME06.07.2021
Validation statesKH06.07.2021
MA06.07.2021
MD06.07.2021
TN06.07.2021
TitleGerman:ZUSAMMENSETZUNGEN UND VERFAHREN ZUR BEHANDLUNG UND VORBEUGUNG VON AMYOTROPHER LATERALSKLEROSE[2021/42]
English:COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING AMYOTROPHIC LATERAL SCLEROSIS[2021/42]
French:COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT ET LA PRÉVENTION DE LA SCLÉROSE LATÉRALE AMYOTROPHIQUE (SLA)[2021/42]
Entry into regional phase06.07.2021National basic fee paid 
06.07.2021Designation fee(s) paid 
06.07.2021Examination fee paid 
Examination procedure06.07.2021Amendment by applicant (claims and/or description)
06.07.2021Examination requested  [2021/42]
06.07.2021Date on which the examining division has become responsible
23.05.2023Despatch of a communication from the examining division (Time limit: M06)
27.11.2023Reply to a communication from the examining division
Fees paidRenewal fee
30.11.2021Renewal fee patent year 03
20.12.2022Renewal fee patent year 04
19.12.2023Renewal fee patent year 05
19.12.2024Renewal fee patent year 06
17.12.2025Renewal fee patent year 07
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Cited inInternational search[I] WO2015153800  (ISIS PHARMACEUTICALS INC et al.)
 [A] WO2018204786  (VOYAGER THERAPEUTICS INC et al.)
 [I]   ALEX MCCAMPBELL ET AL: "Antisense oligonucleotides extend survival and reverse decrement in muscle response in ALS models", JOURNAL OF CLINICAL INVESTIGATION, vol. 128, no. 8, 16 July 2018 (2018-07-16), GB, pages 3558 - 3567, XP055679194, ISSN: 0021-9738, DOI: 10.1172/JCI99081

DOI:   http://dx.doi.org/10.1172/JCI99081
 [A]   SCHOCH KATHLEEN M ET AL: "Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases", NEURON, vol. 94, no. 6, 21 June 2017 (2017-06-21), pages 1056 - 1070, XP085093439, ISSN: 0896-6273, DOI: 10.1016/J.NEURON.2017.04.010

DOI:   http://dx.doi.org/10.1016/j.neuron.2017.04.010
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