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EP3866799
European procedure
Extract from the Register of European Patents
EP Citations: EP3866799
| Cited in | Search | Type: | Non-patent literature | Publication information: | [XAI] DOYLE JEFFERSON J ET AL: "A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome", ELIFE, vol. 4, 27 October 2015 (2015-10-27), pages 1 - 18, XP055927548, Retrieved from the Internet | DOI: | http://dx.doi.org/10.7554/eLife.08648 | Type: | Non-patent literature | Publication information: | [A] BERIDZE NATALIA ET AL: "Vascular Ehlers-Danlos syndrome: pathophysiology, diagnosis, and prevention and treatment of its complications", CARDIOLOGY IN REVIEW, LIPPINCOTT WILLIAMS & WILKINS, US, vol. 20, no. 1, 31 December 2011 (2011-12-31), pages 4 - 7, XP009508098, ISSN: 1538-4683, DOI: 10.1097/CRD.0B013E3182342316 [A] 12-14 * Title * * abstract * * page 6, column r, line 1 - line 13 * | DOI: | http://dx.doi.org/10.1097/CRD.0b013e3182342316 | Cited in | International search | Type: | Patent literature | Publication No.: | WO2018160987
[XY] (UNIV JOHNS HOPKINS et al.) [X] 1, 3-4, 10-15, 26-27, 28/26-27 * ; figure 2A, figure 4C; paragraphs [0007], [0012]-[0013], [0021], [0024], [0030], [0104]-[0105], [0137], [0192], [0209]; claim 36 *[Y] 2,- 5-9 | Type: | Patent literature | Publication No.: | WO2017079399
[Y] (GENENTECH INC et al.) [Y] 5 * ; paragraphs [0006], [0014]-[0015]. [0022] * | Type: | Patent literature | Publication No.: | DE102004019413
[A] (PHENOS GMBH et al.) [A] 1-15, 26-27, 28/26-27 * ; entire document * | Type: | Non-patent literature | Publication information: | [Y] BADE, MA ET AL.: "Endovascular abdominal aortic aneurysm repair in a patient with Ehlers-Danlos syndrome", JOURNAL OF VASCULAR SURGERY, vol. 46, no. 2, 2007, pages 360 - 362, XP022694574, DOI: 10.1016/j.jvs.2007.03.045 [Y] 2 * ; abstract; page 361, heading discussion * | DOI: | http://dx.doi.org/10.1016/j.jvs.2007.03.045 | Type: | Non-patent literature | Publication information: | [Y] SHARP, TE ET AL.: "Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction", JACC: BASIC TO TRANSLATIONAL SCIENCE, vol. 2, no. 6, 2017, pages 669 - 683, XP55710149 [Y] 6 * ; abstract * | Type: | Non-patent literature | Publication information: | [Y] LEPPANEN, T ET AL.: "Protein Kinase C and its Inhibitors in the Regulation of Inflammation: Inducible Nitric Oxide Synthase as an Example", BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, vol. 114, 2014, pages 37 - 43, XP055529503, DOI: 10.1111/bcpt.12139 [Y] 7 * ; abstract; page 38, heading protein kinase c as a target for drug devel * | DOI: | http://dx.doi.org/10.1111/bcpt.12139 | Type: | Non-patent literature | Publication information: | [Y] HE, X ET AL.: "Targeting PKC in Human T Cells Using Sotrastaurin (AEB071) Preserves Regulatory T Cells and Prevents IL -17 Production", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 134, no. 4, 2014, pages 975 - 983, XP055806835 [Y] 8 * ; abstract * | DOI: | http://dx.doi.org/10.1038/jid.2013.459 | Type: | Non-patent literature | Publication information: | [Y] LIN, Y ET AL.: "Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan", SCIENTIFIC REPORTS, vol. 5, 5 October 2015 (2015-10-05), pages 1 - 12, XP55710153 [Y] 9 * ; abstract * | Cited in | by applicant | Type: | Patent literature | Publication No.: | US6468798
| Type: | Patent literature | Publication No.: | US4522811
| Type: | Non-patent literature | Publication information: | "The Cambridge Dictionary of Science and Technology", 1988 | Type: | Non-patent literature | Publication information: | HALEMARHAM: "The Harper Collins Dictionary of Biology", 1991, SPRINGER VERLAG [Y] 6 * ; abstract * | Type: | Non-patent literature | Publication information: | PEPIN MSCHWARZE USUPERTI-FURGA ABYERS PH: "Clinical and Genetic Features of Ehlers-Danlos Syndrome Type IV, the Vascular Type", NENGL JMED, vol. 342, no. 10, 2000, pages 673 - 680 [Y] 7 * ; abstract; page 38, heading protein kinase c as a target for drug devel * | Type: | Non-patent literature | Publication information: | PEPIN MGSCHWARZE URICE KMLIU MLEISTRITZ DRUBYERS PH: "Survival is affected by mutation type and molecular mechanism in vascular Ehlers-Danlos syndrome (EDS type IV", GENET MED, vol. 16, no. 12, 2014, pages 881 - 888, XP055930580, DOI: 10.1038/gim.2014.72 [Y] 8 * ; abstract * | DOI: | http://dx.doi.org/10.1038/gim.2014.72 | Type: | Non-patent literature | Publication information: | HABASHI JPJUDGE DPHOLM TM ET AL.: "Losartan, an ATI Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome", SCIENCE, vol. 312, no. 5770, 2006, pages 117 - 121, XP002540762, DOI: 10.1126/science.1124287 [Y] 9 * ; abstract * | DOI: | http://dx.doi.org/10.1126/science.1124287 | Type: | Non-patent literature | Publication information: | HABASHI JPDOYLE JJHOLM TM ET AL.: "Angiotensin II Type 2 Receptor Signaling Attenuates Aortic Aneurysm in Mice Through ERK Antagonism", SCIENCE, vol. 332, no. 6027, 2011, pages 361 - 365 | Type: | Non-patent literature | Publication information: | JUDGE DPBIERY NJKEENE DR ET AL.: "Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome", J CLIN INVEST, vol. 114, no. 2, 2004, XP055410202, DOI: 10.1172/JCI200420641 | DOI: | http://dx.doi.org/10.1172/JCI200420641 | Type: | Non-patent literature | Publication information: | DOYLE JJDOYLE AJWILSON NK ET AL.: "A deleterious gene-by-environment interaction imposed by calcium channel blockers in Marfan syndrome", ELIFE, no. 4, 2015, pages 4 | Type: | Non-patent literature | Publication information: | LARKIN JASCIERTO PADRENO B ET AL.: "Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma", N ENGLJ MED, vol. 371, no. 20, 2014, pages 1867 - 1876, XP055429850, DOI: 10.1056/NEJMoa1408868 | DOI: | http://dx.doi.org/10.1056/NEJMoa1408868 | Type: | Non-patent literature | Publication information: | PKC-DRS2 GROUP LAIELLO LPDAVIS MD ET AL.: "Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy", OPHTHALMOLOGY, vol. 113, no. 12, 2006, pages 2221 - 2230, XP025037636, DOI: 10.1016/j.ophtha.2006.07.032 | DOI: | http://dx.doi.org/10.1016/j.ophtha.2006.07.032 | Type: | Non-patent literature | Publication information: | GURNEY AMALLAM M: "Inhibition of calcium release from the sarcoplasmic reticulum of rabbit aorta by hydralazine", BR J PHARMACOL, vol. 114, no. 1, 1995, pages 238 - 244 | Type: | Non-patent literature | Publication information: | HABASHI JPGALLO EMBAGIRZADEH R ET AL., A MOUSE MODEL OF MARFAN SYNDROME, 2018 | Type: | Non-patent literature | Publication information: | D'HONDT SGUILLEMYN BSYX D ET AL.: "Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3al transgenic mouse model", MATRIX BIOL, vol. 379, 2018, pages 1343 - 1352 | Type: | Non-patent literature | Publication information: | MANNING MMISICKA AOLMA A ET AL.: "Oxytocin and Vasopressin Agonists and Antagonists as Research Tools and Potential Therapeutics", JNEUROENDOCRINOL, vol. 24, no. 4, 2012, pages 609 - 628, XP055322591, DOI: 10.1111/j.1365-2826.2012.02303.x | DOI: | http://dx.doi.org/10.1111/j.1365-2826.2012.02303.x | Type: | Non-patent literature | Publication information: | LUO RJIN ZDENG YSTROKES NPIAO X: "PLoS One", vol. 7, 2012, article "Disease-Associated Mutations Prevent GPR56-Collagen III Interaction", pages: e29818 | Type: | Non-patent literature | Publication information: | LUO RJEONG S-JYANG A ET AL.: "Mechanism for Adhesion G Protein-Coupled Receptor GPR56", MEDIATED RHOA ACTIVATION INDUCED BY COLLAGEN III STIMULATION, 2014 | Type: | Non-patent literature | Publication information: | ONG KTPERDU JDE BACKER J ET AL.: "Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: A prospective randomised, open, blinded-endpoints trial", LANCET, vol. 376, no. 9751, 2010, pages 1476 - 1484, XP027598350, DOI: 10.1016/S0140-6736(10)60960-9 | DOI: | http://dx.doi.org/10.1016/S0140-6736(10)60960-9 | Type: | Non-patent literature | Publication information: | BRIEST WCOOPER TKTAE H-JKRAWCZYK MMCDONNELL NBTALAN MI: "Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome", J PHARMACOLEXP THER, no. 3, 2011, pages 337 | Type: | Non-patent literature | Publication information: | SHALHUB SBLACK JHCECCHI AC ET AL.: "Molecular diagnosis in vascular Ehlers-Danlos syndrome predicts pattern of arterial involvement and outcomes", J VASC SURG |