EP3870104 - METHODS AND MATERIALS FOR TREATING CANCER [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 30.07.2021 Database last updated on 04.11.2024 | |
Former | The international publication has been made Status updated on 02.05.2020 | Most recent event Tooltip | 13.09.2024 | New entry: Renewal fee paid | Applicant(s) | For all designated states Mayo Foundation for Medical Education and Research 200 First Street S.W. Rochester, Minnesota 55905 / US | [2021/35] | Inventor(s) | 01 /
KARNITZ, Larry M. 3223 Darcy Drive Rochester, Minnesota 55906-8394 / US | 02 /
KANAKKANTHARA, Arun 4617 13th Ave NW Rochester, Minnesota 55901-0451 / US | [2021/35] | Representative(s) | Fish & Richardson P.C. Highlight Business Towers Mies-van-der-Rohe-Straße 8 80807 München / DE | [2021/35] | Application number, filing date | 19874866.7 | 24.10.2019 | [2021/35] | WO2019US57836 | Priority number, date | US201862751358P | 26.10.2018 Original published format: US 201862751358 P | US201962863065P | 18.06.2019 Original published format: US 201962863065 P | [2021/35] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | WO2020086830 | Date: | 30.04.2020 | Language: | EN | [2020/18] | Type: | A2 Application without search report | No.: | EP3870104 | Date: | 01.09.2021 | Language: | EN | The application published by WIPO in one of the EPO official languages on 30.04.2020 takes the place of the publication of the European patent application. | [2021/35] | Search report(s) | International search report - published on: | US | 30.07.2020 | (Supplementary) European search report - dispatched on: | EP | 20.10.2022 | Classification | IPC: | A61K31/235, A61F2/06, A61K31/352, A61K45/00, A61P35/00, A61K31/502, A61K45/06, A61K31/506, A61K31/65 | [2022/33] | CPC: |
A61K31/506 (EP,US);
A61K31/53 (US);
A61K31/235 (EP,US);
A61K31/502 (EP);
A61K31/65 (EP,US);
A61K33/243 (EP,US);
| C-Set: |
A61K31/235, A61K2300/00 (EP);
A61K31/502, A61K2300/00 (EP);
A61K31/506, A61K2300/00 (EP);
A61K31/65, A61K2300/00 (EP); |
Former IPC [2021/35] | A61F2/06, A61K31/352, A61K45/00, A61P35/00 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2021/35] | Title | German: | VERFAHREN UND MATERIALIEN ZUR BEHANDLUNG VON KREBS | [2021/35] | English: | METHODS AND MATERIALS FOR TREATING CANCER | [2021/35] | French: | MÉTHODES ET SUBSTANCES POUR LE TRAITEMENT DU CANCER | [2021/35] | Entry into regional phase | 26.05.2021 | National basic fee paid | 26.05.2021 | Search fee paid | 26.05.2021 | Designation fee(s) paid | 26.05.2021 | Examination fee paid | Examination procedure | 26.05.2021 | Examination requested [2021/35] | 19.05.2023 | Amendment by applicant (claims and/or description) | Fees paid | Renewal fee | 26.05.2021 | Renewal fee patent year 03 | 27.10.2022 | Renewal fee patent year 04 | 27.10.2023 | Renewal fee patent year 05 | 12.09.2024 | Renewal fee patent year 06 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [Y]WO2016175357 (IMMUNOMET THERAPEUTICS INC [US]) [Y] 1-5 * p. 10/11, in particular p. 11, l. 9. *; | [Y]WO2017070198 (DANA FARBER CANCER INST INC [US]) [Y] 1-5 * claims 28-34; claims 10+18; claims 1+9; p. 19, last §;p. 13, l. 1-4; Fig. 4A; p. 36, l. 10-12 *; | [A] - Krasich Rachel ET AL, "DNA polymerases in the mitochondria A critical review of the evidence", Frontiers in bioscience, Singapore, doi:10.2741/4510, (20170101), pages 692 - 709, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485829/pdf/nihms867901.pdf, (20220706), XP055939242 [A] 1-5 * p. 24, last col of table 2 * DOI: http://dx.doi.org/10.2741/4510 | [XY] - YEO SYN KOK ET AL, "Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer", AUTOPHAGY, US, (20180703), vol. 14, no. 7, doi:10.1080/15548627.2018.1460010, ISSN 1554-8627, pages 1214 - 1225, XP055939686 [X] 1 * title, abstract; Fig. 6E * [Y] 1-4 DOI: http://dx.doi.org/10.1080/15548627.2018.1460010 | [Y] - PRIVAT MAUD ET AL, "BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells", PLOS ONE, (20140710), vol. 9, no. 7, doi:10.1371/journal.pone.0102438, page e102438, XP055939521 [Y] 1-5 * title, abstract * DOI: http://dx.doi.org/10.1371/journal.pone.0102438 | [Y] - MOLINA JENNIFER R ET AL, "An inhibitor of oxidative phosphorylation exploits cancer vulnerability", NATURE MEDICINE, NATURE PUBLISHING GROUP US, NEW YORK, vol. 24, no. 7, doi:10.1038/S41591-018-0052-4, ISSN 1078-8956, (20180611), pages 1036 - 1046, (20180611), XP036542082 [Y] 1-4 * title, abstract; Fig. 1, p, 1040, col. 1, last §; Fig. 2 * DOI: http://dx.doi.org/10.1038/s41591-018-0052-4 | [IPY] - KANAKKANTHARA ARUN ET AL, "BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents", CANCER RESEARCH, US, vol. 79, no. 23, doi:10.1158/0008-5472.CAN-19-1405, ISSN 0008-5472, (20191201), pages 5920 - 5929, URL: https://aacrjournals.org/cancerres/article-pdf/79/23/5920/2786362/5920.pdf, XP055939523 [IP] 1-5 * title, abstract; Fig. 3 * [Y] 1-5 DOI: http://dx.doi.org/10.1158/0008-5472.CAN-19-1405 | [Y] - GUMASTE P V ET AL, "Skin cancer risk in BRCA1/2 mutation carriers", BRITISH JOURNAL OF DERMATOLOGY, JOHN WILEY, HOBOKEN, USA, (20150429), vol. 172, no. 6, doi:10.1111/BJD.13626, ISSN 0007-0963, pages 1498 - 1506, XP071118790 [Y] 1-5 * title, abstract * DOI: http://dx.doi.org/10.1111/bjd.13626 | [A] - THAKUR SHILPA ET AL, "Metformin Targets Mitochondrial Glycerophosphate Dehydrogenase to Control Rate of Oxidative Phosphorylation and Growth of Thyroid Cancer In Vitro and In Vivo", CLINICAL CANCER RESEARCH, US, vol. 24, no. 16, doi:10.1158/1078-0432.CCR-17-3167, ISSN 1078-0432, (20180814), pages 4030 - 4043, URL: https://aacrjournals.org/clincancerres/article-pdf/24/16/4030/2047602/4030.pdf, XP055939585 [A] 1-5 * title, abstract * DOI: http://dx.doi.org/10.1158/1078-0432.CCR-17-3167 | [A] - CHEN ALICE ET AL, "PARP inhibitors: its role in treatment of cancer", ATZHENG -CHINESE JOURNAL OF CANCER, CN, doi:10.5732/cjc.011.10111, ISSN 1000-467X, (20110705), pages 463 - 471, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013421/pdf/cjc-30-07-463.pdf, XP055824005 [A] 1-5 * title, abstract * DOI: http://dx.doi.org/10.5732/cjc.011.10111 | [A] - MYLAVARAPU SANGHAMITRA ET AL, "Role of BRCA Mutations in the Modulation of Response to Platinum Therapy", FRONTIERS IN ONCOLOGY, (20180205), vol. 8, doi:10.3389/fonc.2018.00016, XP055939671 [A] 1-5 * title, abstract; p. 6, last § to * DOI: http://dx.doi.org/10.3389/fonc.2018.00016 | International search | [X]US2007254037 (POPOWSKI YOURI [CH]) [X] 1-3 * entire document *; | [X]US2010254982 (GLOVER NICHOLAS RONALD [CA], et al) [X] 17-19 * entire document *; | [A]US2014348749 (BIRSOY KIVANC [US], et al) [A] 1-3, 9-11, 17-19 * entire document *; | [X]US2016030364 (PAUL KERRY [NZ], et al) [X] 9-11 * entire document *; | [PA]WO2018213764 (LUNELLA BIOTECH INC [CA], et al) [PA] 1-3, 9-11, 17-19* entire document * |