blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP3870104

EP3870104 - METHODS AND MATERIALS FOR TREATING CANCER [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  30.07.2021
Database last updated on 04.11.2024
FormerThe international publication has been made
Status updated on  02.05.2020
Most recent event   Tooltip13.09.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Mayo Foundation for Medical Education and Research
200 First Street S.W.
Rochester, Minnesota 55905 / US
[2021/35]
Inventor(s)01 / KARNITZ, Larry M.
3223 Darcy Drive
Rochester, Minnesota 55906-8394 / US
02 / KANAKKANTHARA, Arun
4617 13th Ave NW
Rochester, Minnesota 55901-0451 / US
 [2021/35]
Representative(s)Fish & Richardson P.C.
Highlight Business Towers
Mies-van-der-Rohe-Straße 8
80807 München / DE
[2021/35]
Application number, filing date19874866.724.10.2019
[2021/35]
WO2019US57836
Priority number, dateUS201862751358P26.10.2018         Original published format: US 201862751358 P
US201962863065P18.06.2019         Original published format: US 201962863065 P
[2021/35]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2020086830
Date:30.04.2020
Language:EN
[2020/18]
Type: A2 Application without search report 
No.:EP3870104
Date:01.09.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 30.04.2020 takes the place of the publication of the European patent application.
[2021/35]
Search report(s)International search report - published on:US30.07.2020
(Supplementary) European search report - dispatched on:EP20.10.2022
ClassificationIPC:A61K31/235, A61F2/06, A61K31/352, A61K45/00, A61P35/00, A61K31/502, A61K45/06, A61K31/506, A61K31/65
[2022/33]
CPC:
A61K31/506 (EP,US); A61K31/53 (US); A61K31/235 (EP,US);
A61K31/502 (EP); A61K31/65 (EP,US); A61K33/243 (EP,US);
A61K45/06 (EP); A61P35/00 (US) (-)
C-Set:
A61K31/235, A61K2300/00 (EP);
A61K31/502, A61K2300/00 (EP);
A61K31/506, A61K2300/00 (EP);
A61K31/65, A61K2300/00 (EP);
A61K33/243, A61K2300/00 (EP)
(-)
Former IPC [2021/35]A61F2/06, A61K31/352, A61K45/00, A61P35/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/35]
TitleGerman:VERFAHREN UND MATERIALIEN ZUR BEHANDLUNG VON KREBS[2021/35]
English:METHODS AND MATERIALS FOR TREATING CANCER[2021/35]
French:MÉTHODES ET SUBSTANCES POUR LE TRAITEMENT DU CANCER[2021/35]
Entry into regional phase26.05.2021National basic fee paid 
26.05.2021Search fee paid 
26.05.2021Designation fee(s) paid 
26.05.2021Examination fee paid 
Examination procedure26.05.2021Examination requested  [2021/35]
19.05.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
26.05.2021Renewal fee patent year 03
27.10.2022Renewal fee patent year 04
27.10.2023Renewal fee patent year 05
12.09.2024Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]WO2016175357  (IMMUNOMET THERAPEUTICS INC [US]) [Y] 1-5 * p. 10/11, in particular p. 11, l. 9. *;
 [Y]WO2017070198  (DANA FARBER CANCER INST INC [US]) [Y] 1-5 * claims 28-34; claims 10+18; claims 1+9; p. 19, last §;p. 13, l. 1-4; Fig. 4A; p. 36, l. 10-12 *;
 [A]  - Krasich Rachel ET AL, "DNA polymerases in the mitochondria A critical review of the evidence", Frontiers in bioscience, Singapore, doi:10.2741/4510, (20170101), pages 692 - 709, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485829/pdf/nihms867901.pdf, (20220706), XP055939242 [A] 1-5 * p. 24, last col of table 2 *

DOI:   http://dx.doi.org/10.2741/4510
 [XY]  - YEO SYN KOK ET AL, "Improved efficacy of mitochondrial disrupting agents upon inhibition of autophagy in a mouse model of BRCA1-deficient breast cancer", AUTOPHAGY, US, (20180703), vol. 14, no. 7, doi:10.1080/15548627.2018.1460010, ISSN 1554-8627, pages 1214 - 1225, XP055939686 [X] 1 * title, abstract; Fig. 6E * [Y] 1-4

DOI:   http://dx.doi.org/10.1080/15548627.2018.1460010
 [Y]  - PRIVAT MAUD ET AL, "BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells", PLOS ONE, (20140710), vol. 9, no. 7, doi:10.1371/journal.pone.0102438, page e102438, XP055939521 [Y] 1-5 * title, abstract *

DOI:   http://dx.doi.org/10.1371/journal.pone.0102438
 [Y]  - MOLINA JENNIFER R ET AL, "An inhibitor of oxidative phosphorylation exploits cancer vulnerability", NATURE MEDICINE, NATURE PUBLISHING GROUP US, NEW YORK, vol. 24, no. 7, doi:10.1038/S41591-018-0052-4, ISSN 1078-8956, (20180611), pages 1036 - 1046, (20180611), XP036542082 [Y] 1-4 * title, abstract; Fig. 1, p, 1040, col. 1, last §; Fig. 2 *

DOI:   http://dx.doi.org/10.1038/s41591-018-0052-4
 [IPY]  - KANAKKANTHARA ARUN ET AL, "BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents", CANCER RESEARCH, US, vol. 79, no. 23, doi:10.1158/0008-5472.CAN-19-1405, ISSN 0008-5472, (20191201), pages 5920 - 5929, URL: https://aacrjournals.org/cancerres/article-pdf/79/23/5920/2786362/5920.pdf, XP055939523 [IP] 1-5 * title, abstract; Fig. 3 * [Y] 1-5

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-19-1405
 [Y]  - GUMASTE P V ET AL, "Skin cancer risk in BRCA1/2 mutation carriers", BRITISH JOURNAL OF DERMATOLOGY, JOHN WILEY, HOBOKEN, USA, (20150429), vol. 172, no. 6, doi:10.1111/BJD.13626, ISSN 0007-0963, pages 1498 - 1506, XP071118790 [Y] 1-5 * title, abstract *

DOI:   http://dx.doi.org/10.1111/bjd.13626
 [A]  - THAKUR SHILPA ET AL, "Metformin Targets Mitochondrial Glycerophosphate Dehydrogenase to Control Rate of Oxidative Phosphorylation and Growth of Thyroid Cancer In Vitro and In Vivo", CLINICAL CANCER RESEARCH, US, vol. 24, no. 16, doi:10.1158/1078-0432.CCR-17-3167, ISSN 1078-0432, (20180814), pages 4030 - 4043, URL: https://aacrjournals.org/clincancerres/article-pdf/24/16/4030/2047602/4030.pdf, XP055939585 [A] 1-5 * title, abstract *

DOI:   http://dx.doi.org/10.1158/1078-0432.CCR-17-3167
 [A]  - CHEN ALICE ET AL, "PARP inhibitors: its role in treatment of cancer", ATZHENG -CHINESE JOURNAL OF CANCER, CN, doi:10.5732/cjc.011.10111, ISSN 1000-467X, (20110705), pages 463 - 471, URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013421/pdf/cjc-30-07-463.pdf, XP055824005 [A] 1-5 * title, abstract *

DOI:   http://dx.doi.org/10.5732/cjc.011.10111
 [A]  - MYLAVARAPU SANGHAMITRA ET AL, "Role of BRCA Mutations in the Modulation of Response to Platinum Therapy", FRONTIERS IN ONCOLOGY, (20180205), vol. 8, doi:10.3389/fonc.2018.00016, XP055939671 [A] 1-5 * title, abstract; p. 6, last § to *

DOI:   http://dx.doi.org/10.3389/fonc.2018.00016
International search[X]US2007254037  (POPOWSKI YOURI [CH]) [X] 1-3 * entire document *;
 [X]US2010254982  (GLOVER NICHOLAS RONALD [CA], et al) [X] 17-19 * entire document *;
 [A]US2014348749  (BIRSOY KIVANC [US], et al) [A] 1-3, 9-11, 17-19 * entire document *;
 [X]US2016030364  (PAUL KERRY [NZ], et al) [X] 9-11 * entire document *;
 [PA]WO2018213764  (LUNELLA BIOTECH INC [CA], et al) [PA] 1-3, 9-11, 17-19* entire document *
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.