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Extract from the Register of European Patents

EP About this file: EP3897721

EP3897721 - METHODS OF USING BUTYROPHILIN ANTIBODIES FOR TREATING HIV INFECTION [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  08.02.2024
Database last updated on 03.09.2024
FormerRequest for examination was made
Status updated on  24.09.2021
FormerThe international publication has been made
Status updated on  02.07.2020
Most recent event   Tooltip24.08.2024New entry: Application deemed to be withdrawn: despatch of communication + time limit 
Applicant(s)For all designated states
Merck Sharp & Dohme LLC
126 East Lincoln Avenue
Rahway, New Jersey 07065 / US
[2022/42]
Former [2021/43]For all designated states
Merck Sharp & Dohme Corp.
126 East Lincoln Road
Rahway, New Jersey 07065-0907 / US
Inventor(s)01 / HOWELL, Bonnie Jean
770 Sumneytown Pike
West Point, Pennsylvania 19486 / US
02 / MENG, Hsien-Wei Yvonne
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
03 / MONSLOW, Morgan Ann
770 Sumneytown Pike
West Point, Pennsylvania 19486 / US
04 / SHAHEEN, Hussam Hisham
33 Avenue Louis Pasteur
Boston, Massachusetts 02115-5727 / US
05 / VEMULA, Sai Vikram
2000 Galloping Hill Road
Kenilworth, New Jersey 07033 / US
 [2021/43]
Representative(s)Merck Sharp & Dohme LLC
120 Moorgate
London EC2M 6UR / GB
[N/P]
Former [2021/43]Böhles, Elena
Merck Sharp & Dohme Corp.
120 Moorgate
London, EC2M 6UR / GB
Application number, filing date19901033.117.12.2019
[2021/43]
WO2019US66683
Priority number, dateUS201862781204P18.12.2018         Original published format: US 201862781204 P
[2021/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020131764
Date:25.06.2020
Language:EN
[2020/26]
Type: A1 Application with search report 
No.:EP3897721
Date:27.10.2021
Language:EN
The application published by WIPO in one of the EPO official languages on 25.06.2020 takes the place of the publication of the European patent application.
[2021/43]
Search report(s)International search report - published on:US25.06.2020
(Supplementary) European search report - dispatched on:EP11.08.2022
ClassificationIPC:A61K39/395, A61P31/18, C07K16/28
[2021/43]
CPC:
C07K16/2803 (EP,US); A61P31/18 (EP); C07K2317/30 (US);
C07K2317/33 (EP); C07K2317/70 (EP); C07K2317/76 (EP,US);
C07K2317/92 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/43]
TitleGerman:VERFAHREN ZUR VERWENDUNG VON BUTYROPHILINANTIKÖRPERN ZUR BEHANDLUNG VON HIV-INFEKTIONEN[2021/43]
English:METHODS OF USING BUTYROPHILIN ANTIBODIES FOR TREATING HIV INFECTION[2021/43]
French:PROCÉDÉS D'UTILISATION D'ANTICORPS DE BUTYROPHILINE POUR LE TRAITEMENT D'UNE INFECTION PAR LE VIH[2021/43]
Entry into regional phase19.07.2021National basic fee paid 
19.07.2021Search fee paid 
19.07.2021Designation fee(s) paid 
19.07.2021Examination fee paid 
Examination procedure18.06.2021Observations by third parties
19.07.2021Examination requested  [2021/43]
15.03.2023Amendment by applicant (claims and/or description)
07.02.2024Despatch of a communication from the examining division (Time limit: M06)
23.08.2024Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
Request for further processing for:The application is deemed to be withdrawn due to failure to indicate the wish to proceed further with the application
15.03.2023Request for further processing filed
15.03.2023Full payment received (date of receipt of payment)
Request granted
27.03.2023Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
15.03.2023Request for further processing filed
15.03.2023Full payment received (date of receipt of payment)
Request granted
27.03.2023Decision despatched
Fees paidRenewal fee
16.12.2021Renewal fee patent year 03
09.12.2022Renewal fee patent year 04
12.12.2023Renewal fee patent year 05
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Documents cited:Search[X]US2015353643  (OLIVE DANIEL [FR], et al) [X] 1-13 * paragraph [0158]; claim - * * paragraph [0216] * * paragraph [0328] *;
 [Y]  - Felipe Rubén ET AL, "Section of Infection and Immunity Submitted by", (20160101), URL: https://opus.bibliothek.uni-wuerzburg.de/opus4-wuerzburg/frontdoor/deliver/index/docId/14208/file/Riano_Arias_Ruben_Felipe_T_cells.pdf, (20220719), XP055944035 [Y] 1-13 * Third Party Citation; page 14 * * page 20; figure 1 * * page 46; figure 4 * * page 49 - page 51 * * page 91 * * page 98 - page 99 *
 [Y]  - HEATHER A. ARNETT ET AL, "Immune modulation by butyrophilins", NATURE REVIEWS IMMUNOLOGY, London, (20140725), vol. 14, no. 8, doi:10.1038/nri3715, ISSN 1474-1733, pages 559 - 569, XP055352130 [Y] 1-13 * page 561 - page 562 * * page 564 - page 566 * * figures F3a,b,e *

DOI:   http://dx.doi.org/10.1038/nri3715
 [Y]  - APARNA PALAKODETI ET AL, "The Molecular Basis for Modulation of Human V?9V?2 T Cell Responses by CD277/Butyrophilin-3 (BTN3A)-specific Antibodies", JOURNAL OF BIOLOGICAL CHEMISTRY, US, (20120921), vol. 287, no. 39, doi:10.1074/jbc.M112.384354, ISSN 0021-9258, pages 32780 - 32790, XP055562786 [Y] 1-13 * page 32870 * * page 32871 * * page 32783; figure 2 * * page 32789 *

DOI:   http://dx.doi.org/10.1074/jbc.M112.384354
 [Y]  - C. DAVID PAUZA ET AL, "γΠ́ T Cells in HIV Disease: Past, Present, and Future", FRONTIERS IN IMMUNOLOGY, (20150130), vol. 5, doi:10.3389/fimmu.2014.00687, XP055718000 [Y] 1-13 * page 1 - page 2 * * page 6 *

DOI:   http://dx.doi.org/10.3389/fimmu.2014.00687
International search[X]WO2012080769  (INST NAT SANTE RECH MED [FR], et al) [X] 1-2, 3/1-2, 4-9 * ; page 22. lines 1-3; page 23, lines 18-22; page 37, line 26-page 38, line 5: page 44, lines 9-29 *;
 [Y]  - Yueshui Zhao, Ling Lin, Zhangang Xiao, Mingxing Li, Xu Wu, Wanping Li, Xiaobing Li, Qijie Zhao, Yuanlin Wu, Hanyu Zhang, Jianhua Yin, Lingling Zhang, Chi Hin Cho, Jing Shen, "Protective Role of [gamma-delta) T Cells in Different Pathogen Infections and Its Potential Clinical Application", Journal of Immunology Research, (20180710), vol. 2018, pages 1 - 15, XP055721894 [Y] 7 * , Article ID 5081634, pages 1-15; page 5, 1st column, 3rd paragraph - page 5. 2nd column, 3rd paragraph; page 8, 1st column, 2nd paragraph; DOI: 10.1155/2018/5081634 *

DOI:   http://dx.doi.org/10.1155/2018/5081634
 [A]  - Harly C; Guillaume Y; Nedellec S; C-M Peigne; Monkkonen H; Monkkonen J; Li J; Kuball J; Adams E J; Netzer S; Dechanet-Merville J; Leger A; Herrmann T; Breathnach R; Olive D; Bonneville M; Scotet E, "Key implication of CD 277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human gamma-delta T- cell subset", Blood, (20120913), vol. 120, no. 11, pages 2269 - 2279, XP055081172 [A] 1-2, 3/1-2, 4-9 * ; entire document; DOI: 10.1182/blood-2012-05-430470 *

DOI:   http://dx.doi.org/10.1182/blood-2012-05-430470
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.