EP3663287 - PROCESS SCALE SYNTHESIS OF UROLITHINS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 26.07.2024 Database last updated on 03.09.2024 | |
Former | The patent has been granted Status updated on 18.08.2023 | ||
Former | Grant of patent is intended Status updated on 05.04.2023 | ||
Former | Examination is in progress Status updated on 24.12.2021 | ||
Former | Request for examination was made Status updated on 18.12.2020 | ||
Former | The application has been published Status updated on 08.05.2020 | Most recent event Tooltip | 30.08.2024 | Lapse of the patent in a contracting state New state(s): MC | published on 02.10.2024 [2024/40] | Applicant(s) | For all designated states Amazentis SA EPFL Innovation Park Bâtiment C 1015 Lausanne / CH | [2020/24] | Inventor(s) | 01 /
Rinsch, Christopher EPFL Innovation Park Bâtiment C 1015 Lausanne / CH | 02 /
Skranc, Wolfgang Oberfeldgasse 23 1220 Vienna / AT | 03 /
Müller, Roland Schwaneplatz 2 93047 Regensburg / DE | [2020/24] | Representative(s) | Abel & Imray LLP Westpoint Building James Street West Bath BA1 2DA / GB | [2023/38] |
Former [2020/24] | Abel & Imray Westpoint Building James Street West Bath BA1 2DA / GB | Application number, filing date | 20152975.7 | 22.12.2014 | [2020/24] | Priority number, date | US201361919923P | 23.12.2013 Original published format: US 201361919923 P | [2020/24] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3663287 | Date: | 10.06.2020 | Language: | EN | [2020/24] | Type: | B1 Patent specification | No.: | EP3663287 | Date: | 20.09.2023 | Language: | EN | [2023/38] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 12.05.2020 | Classification | IPC: | C07D311/80 | [2020/24] | CPC: |
C07D311/80 (EP,US);
A61K31/366 (EP,US);
A61K33/34 (US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2021/03]
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Former [2020/24] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | SYNTHESE VON UROLITHINEN IM PROZESSMASSSTAB | [2020/24] | English: | PROCESS SCALE SYNTHESIS OF UROLITHINS | [2020/24] | French: | SYNTHÈSE D'UROLITHINES À L'ÉCHELLE DU PROCÉDÉ | [2020/24] | Examination procedure | 10.12.2020 | Amendment by applicant (claims and/or description) | 10.12.2020 | Examination requested [2021/03] | 10.12.2020 | Date on which the examining division has become responsible | 23.12.2021 | Despatch of a communication from the examining division (Time limit: M06) | 01.07.2022 | Reply to a communication from the examining division | 12.10.2022 | Despatch of a communication from the examining division (Time limit: M02) | 08.12.2022 | Reply to a communication from the examining division | 06.04.2023 | Communication of intention to grant the patent | 11.08.2023 | Fee for grant paid | 11.08.2023 | Fee for publishing/printing paid | 11.08.2023 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP14828105.8 / EP3087065 | Opposition(s) | 21.06.2024 | No opposition filed within time limit [2024/35] | Fees paid | Renewal fee | 21.01.2020 | Renewal fee patent year 03 | 21.01.2020 | Renewal fee patent year 04 | 21.01.2020 | Renewal fee patent year 05 | 21.01.2020 | Renewal fee patent year 06 | 14.12.2020 | Renewal fee patent year 07 | 16.02.2022 | Renewal fee patent year 08 | 14.11.2022 | Renewal fee patent year 09 | Penalty fee | Additional fee for renewal fee | 31.12.2021 | 08   M06   Fee paid on   16.02.2022 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | CZ | 20.09.2023 | ES | 20.09.2023 | HR | 20.09.2023 | MC | 20.09.2023 | PL | 20.09.2023 | RO | 20.09.2023 | RS | 20.09.2023 | SK | 20.09.2023 | SM | 20.09.2023 | NO | 20.12.2023 | GR | 21.12.2023 | IS | 20.01.2024 | [2024/40] |
Former [2024/25] | CZ | 20.09.2023 | |
ES | 20.09.2023 | ||
HR | 20.09.2023 | ||
PL | 20.09.2023 | ||
RO | 20.09.2023 | ||
RS | 20.09.2023 | ||
SK | 20.09.2023 | ||
SM | 20.09.2023 | ||
NO | 20.12.2023 | ||
GR | 21.12.2023 | ||
IS | 20.01.2024 | ||
Former [2024/23] | CZ | 20.09.2023 | |
ES | 20.09.2023 | ||
HR | 20.09.2023 | ||
RO | 20.09.2023 | ||
RS | 20.09.2023 | ||
SK | 20.09.2023 | ||
SM | 20.09.2023 | ||
NO | 20.12.2023 | ||
GR | 21.12.2023 | ||
IS | 20.01.2024 | ||
Former [2024/20] | HR | 20.09.2023 | |
RS | 20.09.2023 | ||
SM | 20.09.2023 | ||
NO | 20.12.2023 | ||
GR | 21.12.2023 | ||
IS | 20.01.2024 | ||
Former [2024/11] | HR | 20.09.2023 | |
RS | 20.09.2023 | ||
NO | 20.12.2023 | ||
GR | 21.12.2023 | ||
Former [2024/08] | NO | 20.12.2023 | |
GR | 21.12.2023 | Documents cited: | Search | [I]WO2004073612 (MERCK & CO INC [US], et al) [I] 1-15* Step 3 of examples 12 and 13;; examples 12, 13, 25, 43, 59 *; | [I]WO2013041461 (MSD OSS BV [NL], et al) [I] 1-15 * conversion of compound 53(f) to 53(g); pages 73, 75; example 52 *; | [X] - ITO ET AL, "Identification of Urinary and Intestinal Bacterial Metabolites of Ellagitannin Geraniin in Rats", J. AGRIC. FOOD CHEM,, (20071229), vol. 56, doi:10.1021/JF0726942, pages 393 - 400, XP002768229 [X] 1,2,4-7,9-11,14 * step iii;; figure 7 * DOI: http://dx.doi.org/10.1021/jf0726942 | [X] - DOBROSLAWA BIALONSKA ET AL, "Urolithins, Intestinal Microbial Metabolites of Pomegranate Ellagitannins, Exhibit Potent Antioxidant Activity in a Cell-Based Assay", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, US, (20091111), vol. 57, no. 21, doi:10.1021/jf9025794, ISSN 0021-8561, pages 10181 - 10186, XP055579614 [X] 1,2,4-7,9-11,14 * Urolithin C synthesis left column; page 3 * DOI: http://dx.doi.org/10.1021/jf9025794 | [I] - SUN WANYING ET AL, "6H-Benzo[c]chromen-6-one derivatives as selective ER[beta] agon", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, (20060118), vol. 16, no. 6, doi:10.1016/J.BMCL.2005.12.057, ISSN 0960-894X, pages 1468 - 1472, XP028755073 [I] 1-15 * Scheme 1 step b;; table 1 * DOI: http://dx.doi.org/10.1016/j.bmcl.2005.12.057 | by applicant | US2011065662 | US2012164243 | US2014018415 | - GIL et al., J. Agric. Food Chem., (20000000), vol. 48, pages 4581 - 4589 | - OKUDA et al., Chem. Pharm. Bull., (19820000), vol. 30, pages 4234 - 4236 | - "Strategies for the synthesis of ellagitannins", KHANBABAEE, K., Chemistry and Biology of Ellagitannins, World Scientific Publishing, (20090000), pages 152 - 202 | - J. HASSAN et al., "Aryl-Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction", Chemical Reviews, (20020000), vol. 102, no. 5, doi:10.1021/cr000664r, pages 1359 - 1470, XP002245414 DOI: http://dx.doi.org/10.1021/cr000664r |