EP3718544 - COMBINATION [Right-click to bookmark this link] | Status | The application has been withdrawn Status updated on 16.06.2023 Database last updated on 31.08.2024 | |
Former | Examination is in progress Status updated on 24.12.2021 | ||
Former | Request for examination was made Status updated on 16.04.2021 | ||
Former | The application has been published Status updated on 04.09.2020 | Most recent event Tooltip | 16.06.2023 | Withdrawal of application | published on 19.07.2023 [2023/29] | Applicant(s) | For all designated states Novartis AG Lichtstrasse 35 4056 Basel / CH | [2020/41] | Inventor(s) | 01 /
CORNFELD, Mark J. 1250 South Collegeville Road Collegeville, PA Pennsylvania 19426 / US | 02 /
KUMAR, Rakesh 1250 South Collegeville Road Collegeville, PA Pennsylvania 19426 / US | 03 /
MORRIS, Shannon Renae 5 Moore Drive Research Triangle Park, NC North Carolina 27709 / US | [2020/41] | Representative(s) | Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [N/P] |
Former [2020/41] | Ammelburg, Jan Moritz c/o Fish & Richardson P.C. Highlight Business Towers Mies-van-der-Rohe-Straße 8 80807 München / DE | Application number, filing date | 20160587.0 | 01.10.2014 | [2020/41] | Priority number, date | US201361885049P | 01.10.2013 Original published format: US 201361885049 P | US201461933379P | 30.01.2014 Original published format: US 201461933379 P | [2020/41] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP3718544 | Date: | 07.10.2020 | Language: | EN | [2020/41] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 22.07.2020 | Classification | IPC: | A61K31/4155, A61K31/4375, A61K31/58, A61K45/06, A61P35/00, A61P35/04, A61P43/00 | [2020/41] | CPC: |
A61K31/58 (EP,KR,MX,US);
A61K31/4155 (EP,KR,MX,US);
A61K31/4196 (KR);
A61K31/4375 (EP,KR,MX,US);
A61K45/06 (EP,KR,MX,US);
A61P13/08 (EP);
A61P35/00 (EP);
A61P35/02 (EP);
A61P35/04 (EP);
| C-Set: |
A61K31/4155, A61K2300/00 (US,EP);
A61K31/4375, A61K2300/00 (US,EP);
A61K31/58, A61K2300/00 (EP,US);
A61K31/58, A61K2300/00, A61K31/4155, A61K2300/00, A61K31/4375, A61K2300/00 (MX) | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2021/20] |
Former [2020/41] | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR | Title | German: | KOMBINATION | [2020/41] | English: | COMBINATION | [2020/41] | French: | COMBINAISON | [2020/41] | Examination procedure | 06.04.2021 | Examination requested [2021/20] | 06.04.2021 | Date on which the examining division has become responsible | 30.06.2021 | Amendment by applicant (claims and/or description) | 04.01.2022 | Despatch of a communication from the examining division (Time limit: M06) | 04.08.2022 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 12.10.2022 | Reply to a communication from the examining division | 07.06.2023 | Application withdrawn by applicant [2023/29] | Parent application(s) Tooltip | EP14790343.9 / EP3052097 | Divisional application(s) | EP23175752.7 | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 12.10.2022 | Request for further processing filed | 12.10.2022 | Full payment received (date of receipt of payment) Request granted | 20.10.2022 | Decision despatched | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 30.06.2021 | Request for further processing filed | 30.06.2021 | Full payment received (date of receipt of payment) Request granted | 09.07.2021 | Decision despatched | Fees paid | Renewal fee | 29.06.2020 | Renewal fee patent year 03 | 29.06.2020 | Renewal fee patent year 04 | 29.06.2020 | Renewal fee patent year 05 | 29.06.2020 | Renewal fee patent year 06 | 01.07.2020 | Renewal fee patent year 07 | 27.10.2021 | Renewal fee patent year 08 | 27.10.2022 | Renewal fee patent year 09 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A]US2008051380 (AUERBACH ALAN H [US], et al) [A] 1-15 * paragraph [0008] - paragraph [0017] * * paragraph [0057]; claims 1-29 *; | [A]WO2010149755 (NOVARTIS AG [CH], et al) [A] 1-15* page 26, line 14 - page 27, line 18; example 58 *; | [Y]WO2012135759 (GENENTECH INC [US], et al) [Y] 1-15 * page 4, line 13 - line 16; figures 1,2; claims 1-15 *; | [Y]WO2012135750 (GENENTECH INC [US], et al) [Y] 1-15 * page 4, line 11 - line 30; claims 1-15 *; | [Y]WO2013079964 (ASTRAZENECA AB [SE], et al) [Y] 1-15 * page 8, line 3 - line 12; claims 1-17 *; | [A] - J. M. CLARKE ET AL, "Novel Therapies for the Treatment of Advanced Prostate Cancer", CURRENT TREATMENT OPTIONS IN ONCOLOGY, (20130116), vol. 14, no. 1, doi:10.1007/s11864-012-0222-4, ISSN 1527-2729, pages 109 - 126, XP055152755 [A] 1-15 * abstract * DOI: http://dx.doi.org/10.1007/s11864-012-0222-4 | [A] - LINA YIN ET AL, "Recent Progress in Pharmaceutical Therapies for Castration-Resistant Prostate Cancer", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, (20130704), vol. 14, no. 7, doi:10.3390/ijms140713958, ISSN 1661-6596, pages 13958 - 13978, XP055115967 [A] 1-15 * abstract * * page 13959, Section 2 * * Conclusions * DOI: http://dx.doi.org/10.3390/ijms140713958 | [A] - F. DAYYANI ET AL, "Novel Therapies for Metastatic Castrate-Resistant Prostate Cancer", JNCI JOURNAL OF THE NATIONAL CANCER INSTITUTE, (20111116), vol. 103, no. 22, doi:10.1093/jnci/djr362, ISSN 0027-8874, pages 1665 - 1675, XP055089916 [A] 1-15 * abstract * DOI: http://dx.doi.org/10.1093/jnci/djr362 | by applicant | US5604213 | US5681835 | US5877219 | US6207716 | US6268391 | WO2008098104 | US7576209 | US2010197754 | - RINI, B.I.SMALL, E.J., "Hormone-refractory prostate cancer", Curr.Treat. Options Oncol., (20020000), vol. 3, page 437 | - SINGH, P.YAM, M.RUSSELL, P.J.KHATRI, A., "Molecular and traditional chemotherapy: a united front against prostate cancer", Cancer Lett., (20100000), vol. 293, page 1 | - SAMUELS YERICSON K, "Oncogenic PI3K and its role in cancer", Current Opinion in Oncology, (20060000), vol. 18, doi:10.1097/01.cco.0000198021.99347.b9, pages 77 - 82, XP009172157 DOI: http://dx.doi.org/10.1097/01.cco.0000198021.99347.b9 | - J. Q. CHEUNG et al., Proc. Natl. Acad. Sci. U.S.A., (19920000), vol. 89, pages 9267 - 9271 | - J. Q. CHEUNG et al., Proc. Natl. Acad. Sci. U. S.A., (19960000), vol. 93, pages 3636 - 3641 | - NAKATANI et al., J. Biol.Chem., (19990000), vol. 274, pages 21528 - 21532 | - BELLACOSA et al., Int. J. Cancer, (19950000), vol. 64, pages 280 - 285 | - SUN, Am. J. Pathol., (20010000), vol. 159, pages 431 - 7 | - LI et al., Science, (19970000), vol. 275, pages 1943 - 1947 | - STAMBOLIC et al., Cell, (19980000), vol. 95, pages 29 - 39 | - SUN et al., Proc. Nati. Acad. Sci. U.S.A., (19990000), vol. 96, pages 6199 - 6204 | - LIAW et al., Nature Genetics, (19970000), vol. 16, pages 64 - 67 | - RISINGER et al., Cancer Research, (19970000), vol. 57, pages 4736 - 4738 | - Pharmaceutical Research, (19860000), vol. 3, no. 6, page 318 | - The Journal of Steroid Biochemistry and Molecular Biology, (20120000), vol. 129, no. 3-5, pages 115 - 28 | - "New treatments for castration-resistant prostate cancer: highlights from the 44th annual meeting of the American society of clinical oncology", Rev Urol, (20080530), vol. 10, no. 4, pages 294 - 6 | - MARKMAN et al., Yale Journal of Biology and Medicine, (19910000), vol. 64, page 583 | - MCGUIRE et al., Ann. Intem, Med., (19890000), vol. 111, page 273 | - HOLMES et al., J. Nat. Cancer Inst., (19910000), vol. 83, page 1797 | - EINZIG, Proc. Am. Soc. Clin. Oncol., vol. 20, page 46 | - FORASTIRE, Sem. Oncol., (19900000), vol. 20, page 56 | - WOO, Nature, (19940000), vol. 368, page 750 | - KEARNS, C.M., Seminars in Oncology, (19950000), vol. 3, no. 6, pages 16 - 23 | - ROSANIA et al., Exp. Opin. Ther. Patents, (20000000), vol. 10, no. 2, pages 215 - 230 | - SHAWVER et al., DDT, (19970200), vol. 2, no. 2 | - SINH, S.COREY, S.J., Journal of Hematotherapy and Stem Cell Research, (19990000), vol. 8, no. 5, pages 465 - 80 | - BOLEN, J.B.BRUGGE, J.S., Annual review of Immunology, (19970000), vol. 15, pages 371 - 404 | - SMITHGALL, T.E., Journal of Pharmacological and Toxicological Methods, (19950000), vol. 34, no. 3, pages 125 - 32 | - YAMAMOTO, T.TAYA, S.KAIBUCHI, K., Journal of Biochemistry, (19990000), vol. 126, no. 5, pages 799 - 803 | - BRODT, PSAMANI, A.NAVAB, R., Biochemical Pharmacology, (20000000), vol. 60, pages 1101 - 1107 | - MASSAGUE, J.WEIS-GARCIA, F., Cancer Surveys, (19960000), vol. 27, pages 41 - 64 | - PHILIP, P.A.HARRIS, A.L., Cancer Treatment and Research, (19950000), vol. 78, pages 3 - 27 | - LACKEY, K. et al., Bioorganic and Medicinal Chemistry Letters, (20000000), vol. 10, pages 223 - 226 | - MARTINEZ-LACACI, L. et al., Int. J. Cancer, (20000000), vol. 88, no. 1, pages 44 - 52 | - ABRAHAM, R.T., Current Opinion in Immunology, (19960000), vol. 8, no. 3, pages 412 - 8 | - CANMAN, C.E.LIM, D.S., Oncogene, (19980000), vol. 17, no. 25, pages 3301 - 3308 | - JACKSON, S.P., International Journal of Biochemistry and Cell Biology, (19970000), vol. 29, no. 7, pages 935 - 8 | - ZHONG, H. et al., Cancer res, (20000000), vol. 60, no. 6, pages 1541 - 1545 | - SCHAROVSKY, O.G.ROZADOS, V.R.GERVASONI, S.I.MATAR, P., Journal of Biomedical Science, (20000000), vol. 7, no. 4, pages 292 - 8 | - ASHBY, M.N., Current Opinion in Lipidology, (19980000), vol. 9, no. 2, pages 99 - 102 | - BioChim. Biophys. Acta, vol. 1423, no. 3, pages 19 - 30 | - GREEN, M.C. et al., "Monoclonal Antibody Therapy for Solid Tumors", Cancer Treat. Rev., (20000000), vol. 26, no. 4, doi:10.1053/ctrv.2000.0176, pages 269 - 286, XP009019784 DOI: http://dx.doi.org/10.1053/ctrv.2000.0176 | - "Tyrosine Kinase Signalling in Breast cancer:erbB Family Receptor Tyrosine Kinases", Breast cancer Res., (20000000), vol. 2, no. 3, pages 176 - 183 | - BREKKEN, R.A. et al., "Selective Inhibition of VEGFR2 Activity by a monoclonal Anti-VEGF antibody blocks tumor growth in mice", Cancer Res., (20000000), vol. 60, pages 5117 - 5124, XP002340113 | - BALL et al., Progress in Cell Cycle Res., (19970000), vol. 3, page 125 | - RICHON et al., Proc. Nat Acad. Sci. U.S.A., (20000000), vol. 97, no. 18, pages 10014 - 10019 | - VIGUSHIN et al., Anticancer Drugs, (20020100), vol. 13, no. 1, pages 1 - 13 | - MARKS et al., Nature Biotechnology, (20070000), vol. 25, pages 84 - 90 | - STENGER, Community Oncology, (20070000), vol. 4, pages 384 - 386 | - VINODHKUMAR et al., Biomedicine & Pharmacotherapy, (20080000), vol. 62, pages 85 - 93 | - Drugs of the Future, (20070000), vol. 32, no. 4, pages 315 - 322 | - GOTTLICHER et al., EMBO J., (20010000), vol. 20, no. 24, pages 6969 - 6978 | - BALASUBRAMANIAN et al., Cancer Letters, (20090000), vol. 280, pages 211 - 221 | - BERTRAND, European Journal of Medicinal Chemistry, (20100000), vol. 45, pages 2095 - 2116 | - ADAMS JKAUFFMAN M, Cancer Invest, (20040000), vol. 22, no. 2, pages 304 - 11 | - BOUMA et al., J. Antimicrob. Chemother., (19980000), vol. 42, no. 6, pages 817 - 20 | - WILLIAMSON et al., The Journal of Allergy and Clinical Immunology, (20061200), vol. 118, no. 6, pages 1369 - 74 | - FELING, Angew. Chem. Int. Ed. Engl., (20030000), vol. 42, no. 3, pages 355 - 7 | - KUHN DJ et al., Blood, (20070000), vol. 110, pages 3281 - 3290 | - JIA W, Blood, (20030901), vol. 102, no. 5, pages 1824 - 32 | - LEE et al., Mol Cell Endocrinol., (20020000), vol. 188, pages 47 - 54 | - D. A. TENNANT, Nature Reviews, (20100000), vol. 267 | - P. LEDER, Cancer Cell, (20060000), vol. 9, page 425 | - ALII et al., Oncogene, (20050000), vol. 24, pages 39 - 46 | - LIU, Q et al., Human Mutation, (20040000), vol. 23, pages 426 - 436 | - CHOUTALALAY, Advances in Enzyme Regulation, (19840000), vol. 22, pages 37 - 55 | - BERENBAUM, MC, Adv. Cancer Research, (19810000), vol. 35, pages 269 - 335 | WO2008US53269 |