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EP About this file: EP3730615

EP3730615 - METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  30.09.2022
Database last updated on 16.09.2024
FormerRequest for examination was made
Status updated on  11.06.2021
FormerThe application has been published
Status updated on  28.09.2020
Most recent event   Tooltip29.07.2024New entry: Additional fee for renewal fee: payment of fee 
29.07.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Sangamo Therapeutics, Inc.
Point Richmond Tech Center
501 Canal Boulevard, Suite A100
Richmond, CA 94804 / US
[2020/44]
Inventor(s)01 / CONWAY, Anthony
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
02 / COST, Gregory J.
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
03 / DEKELVER, Russell
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
04 / REBAR, Edward J.
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
05 / REIK, Andreas
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
06 / URNOV, Fyodor
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
07 / WANG, Jianbin
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
08 / ZHANG, H. Steve
c/o Sangamo BioSciences, Inc.
Point Richmond Tech Center
501 Canal Boulevard
Suite A100
Richmond, CA California 94804 / US
 [2020/44]
Representative(s)Weickmann & Weickmann PartmbB
Postfach 860 820
81635 München / DE
[N/P]
Former [2020/44]Weiss, Wolfgang
Weickmann & Weickmann
Patent- und Rechtsanwälte PartmbB
Postfach 860 820
81635 München / DE
Application number, filing date20173697.215.05.2014
[2020/44]
Priority number, dateUS201361823689P15.05.2013         Original published format: US 201361823689 P
[2020/44]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report 
No.:EP3730615
Date:28.10.2020
Language:EN
[2020/44]
Type: A3 Search report 
No.:EP3730615
Date:09.12.2020
Language:EN
[2020/50]
Search report(s)(Supplementary) European search report - dispatched on:EP06.11.2020
ClassificationIPC:C12N15/11, C12N9/22, C12N15/90, C12N15/63, C07K14/805
[2020/44]
CPC:
C07K14/805 (EP); C12N15/907 (US); C07K2/00 (US);
C12N15/11 (US); C12N15/63 (EP); C12N15/90 (US);
C12N15/902 (EP,US); C12N9/22 (EP,US); C07K2319/81 (US);
C12N2320/30 (US); C12Y301/21004 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2021/28]
Former [2020/44]AL,  AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MK,  MT,  NL,  NO,  PL,  PT,  RO,  RS,  SE,  SI,  SK,  SM,  TR 
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG EINES GENETISCHEN LEIDENS[2020/44]
English:METHODS AND COMPOSITIONS FOR TREATMENT OF A GENETIC CONDITION[2020/44]
French:PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT D'UNE MALADIE GÉNÉTIQUE[2020/44]
Examination procedure09.06.2021Amendment by applicant (claims and/or description)
09.06.2021Examination requested  [2021/28]
09.06.2021Date on which the examining division has become responsible
05.10.2022Despatch of a communication from the examining division (Time limit: M04)
08.02.2023Reply to a communication from the examining division
Parent application(s)   TooltipEP14797155.0  / EP2997146
Fees paidRenewal fee
08.05.2020Renewal fee patent year 03
08.05.2020Renewal fee patent year 04
08.05.2020Renewal fee patent year 05
08.05.2020Renewal fee patent year 06
08.05.2020Renewal fee patent year 07
27.05.2021Renewal fee patent year 08
27.05.2022Renewal fee patent year 09
30.05.2023Renewal fee patent year 10
29.07.2024Renewal fee patent year 11
Penalty fee
Additional fee for renewal fee
31.05.202411   M06   Fee paid on   29.07.2024
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO2010030963  (CHILDRENS MEDICAL CENTER [US], et al) [A] 1-15 * claims 1-32 *;
 [A]WO2013044008  (SANGAMO BIOSCIENCES INC [US]) [A] 1-15 * pages 6-19; examples 1-8; claims 1-10 *;
 [XP]WO2013126794  (HUTCHINSON FRED CANCER RES [US]) [XP] 1,4,7,9,13-15 * abstract * * paragraph [0020] *;
 [AP]WO2014036219  (SANGAMO BIOSCIENCES INC [US]) [AP] 1-15 * paragraphs [0015] - [0022] *;
 [Y]  - MALI P. ET AL, "RNA-guided human genome engineering via Cas9", SCIENCE, US, (20130215), vol. 339, no. 6121, doi:10.1126/science.1232033, ISSN 0036-8075, pages 823 - 826, XP055300091 [Y] 1-15 * abstract * * figures 1-2 *

DOI:   http://dx.doi.org/10.1126/science.1232033
 [Y]  - THOMAS GAJ ET AL, "ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering", TRENDS IN BIOTECHNOLOGY, (20130501), doi:10.1016/j.tibtech.2013.04.004, ISSN 0167-7799, XP055065263 [Y] 1-15 * abstract * * page 5, column 2; table 1 *

DOI:   http://dx.doi.org/10.1016/j.tibtech.2013.04.004
 [Y]  - VITTORIO SEBASTIANO ET AL, "In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases", STEM CELLS., US, (20111025), vol. 29, no. 11, doi:10.1002/stem.718, ISSN 1066-5099, pages 1717 - 1726, XP055260055 [Y] 1,4,7,9,13-15 * abstract * * page 1718, column 2; figure 3 *

DOI:   http://dx.doi.org/10.1002/stem.718
 [Y]  - DANIEL E BAUER ET AL, "HbF-Associated Genetic Variation Marks an Erythroid Regulatory Element Essential for BCL11A Transcription and Subsequent Stage-Specific Globin Expression", vol. 120, ISSN 0006-4971, (20120101), pages 1 - 5, BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, URL: http://www.bloodjournal.org/content/120/21/828?sso-checked=true, (20170313), XP008183703 [Y] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1182/blood-2012-06-292078
 [XP]  - "Human HBB targeted gRNA sequence, SEQ ID 888.", Geneseq, (20150226), Database accession no. BBT87742, URL: EBI, XP002764441 [XP] 1,4,7,9,13-15 * the whole document *
 [XP]  - "BCL11A gene specific guide RNA (gRNA) targeting domain, SEQ: 9820.", Geneseq, (20151203), Database accession no. BCF10556, URL: EBI, XP002767931 [XP] 1,4,7,9,13-15 * sequence . *
 [A]  - V. G. SANKARAN, "Targeted Therapeutic Strategies for Fetal Hemoglobin Induction", HEMATOLOGY, (20111201), vol. 2011, no. 1, doi:10.1182/asheducation-2011.1.459, ISSN 1520-4391, pages 459 - 465, XP055108964 [A] 1-15 * abstract * * page 461, column 2 *

DOI:   http://dx.doi.org/10.1182/asheducation-2011.1.459
 [A]  - RAECHEL PERALTA ET AL, "Targeting BCL11A and KLF1 For The Treatment Of Sickle Cell Disease and [beta]-Thalassemia In Vitro using Antisense Oligonucleotides", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, (20130101), vol. 122, ISSN 0006-4971, pages 1 - 4, XP008183701 [A] 1-15 * the whole document *
 [A]  - "Sequence 5522 from Patent WO2012149438.", EMBL, (20130404), Database accession no. JA922571, URL: EBI, XP002768137 [A] 1-15 * the whole document *
 [A]  - XAVIER M ANGUELA ET AL, "Paper: In Vivo Genome Editing of Liver Albumin for Therapeutic Gene Expression: Rescue of Hemophilic Mice Via Integration of Factor 9", 54TH ASH ANNUAL MEETING AND EXPOSITION, (20121108), page 751, XP055174905 [A] 1-15 * the whole document *
 [A]  - "Human albumin (ALB) gene-specific PCR primer, SEQ ID 5.", Geneseq, (20120412), Database accession no. AZT61077, URL: EBI, XP002768138 [A] 1-15 * the whole document *
 [A]  - ANDREW WILBER ET AL, "Abstract", BLOOD, US, (20110414), vol. 117, no. 15, doi:10.1182/blood-2010-11-316893, ISSN 0006-4971, pages 3945 - 3953, XP055727086 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1182/blood-2010-11-316893
 [AP]  - T. J. CRADICK ET AL, "CRISPR/Cas9 systems targeting -globin and CCR5 genes have substantial off-target activity", NUCLEIC ACIDS RESEARCH, (20131101), vol. 41, no. 20, doi:10.1093/nar/gkt714, ISSN 0305-1048, pages 9584 - 9592, XP055186069 [AP] 1-15 * abstract * * figure 1; table 1 *

DOI:   http://dx.doi.org/10.1093/nar/gkt714
 [A]  - LE CONG ET AL, "Multiplex Genome Engineering Using CRISPR/Cas Systems", SCIENCE, US, (20130214), vol. 339, no. 6121, doi:10.1126/science.1231143, ISSN 0036-8075, pages 819 - 823, XP055458249 [A] 1-15 * abstract *

DOI:   http://dx.doi.org/10.1126/science.1231143
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