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Extract from the Register of European Patents

EP About this file: EP3972633

EP3972633 - ANTI-ABETA VACCINE THERAPY [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  01.09.2023
Database last updated on 26.07.2024
FormerRequest for examination was made
Status updated on  25.02.2022
FormerThe international publication has been made
Status updated on  27.11.2020
Formerunknown
Status updated on  27.05.2020
Most recent event   Tooltip23.03.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
AC Immune SA
EPFL Innovation Park
Building B
1015 Lausanne / CH
[2022/13]
Inventor(s)01 / PFEIFER, Andrea
c/o AC Immune SA,
EPFL Innovation Park, Building B
1015 Lausanne / CH
02 / MUHS, Andreas
deceased / CH
 [2022/13]
Representative(s)Boult Wade Tennant LLP
Salisbury Square House
8 Salisbury Square
London EC4Y 8AP / GB
[2022/13]
Application number, filing date20726473.020.05.2020
[2022/13]
WO2020EP64172
Priority number, dateEP2019017581021.05.2019         Original published format: EP 19175810
EP2019018559310.07.2019         Original published format: EP 19185593
EP2020017154927.04.2020         Original published format: EP 20171549
EP2020017220529.04.2020         Original published format: EP 20172205
[2022/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020234405
Date:26.11.2020
Language:EN
[2020/48]
Type: A1 Application with search report 
No.:EP3972633
Date:30.03.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 26.11.2020 takes the place of the publication of the European patent application.
[2022/13]
Search report(s)International search report - published on:EP26.11.2020
ClassificationIPC:A61K39/00, A61P25/00, A61P25/28
[2022/13]
CPC:
A61K39/0007 (EP,IL,KR,US); A61K39/39 (US); A61P25/00 (EP,IL,KR);
A61P25/28 (EP,IL,KR,US); A61K2039/54 (KR); A61K2039/545 (EP,IL,KR,US);
A61K2039/55555 (EP,IL,KR); A61K2039/55572 (EP,IL,KR,US); A61K2039/6018 (EP,IL,KR,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/13]
TitleGerman:ANTI-ABETA IMPFSTOFFTHERAPIE[2022/13]
English:ANTI-ABETA VACCINE THERAPY[2022/13]
French:VACCINOTHÉRAPIE ANTI-ABÊTA[2022/13]
Entry into regional phase11.11.2021National basic fee paid 
11.11.2021Designation fee(s) paid 
11.11.2021Examination fee paid 
Examination procedure11.11.2021Examination requested  [2022/13]
11.11.2021Date on which the examining division has become responsible
12.07.2022Amendment by applicant (claims and/or description)
05.09.2023Despatch of a communication from the examining division (Time limit: M04)
15.01.2024Reply to a communication from the examining division
Fees paidRenewal fee
28.03.2022Renewal fee patent year 03
23.03.2023Renewal fee patent year 04
22.03.2024Renewal fee patent year 05
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Cited inInternational search[YD]WO2007068411  (AC IMMUNE SA [CH], et al) [YD] 1-36 *** page 65, claims 4, 7, 14-19, 21, 85 ***;
 [YD]WO2013044147  (AC IMMUNE SA [US], et al) [YD] 1-36*** para, 9, 175, 186; claim 1; Figure 1 ***;
 [YD]  - MUHS ANDREAS ET AL, "Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, (20070605), vol. 104, no. 23, doi:10.1073/PNAS.0703137104, ISSN 0027-8424, pages 9810 - 9815, XP002542049 [YD] 1-36 *** pages 9810, 9813, 9814, Figure 1 ***

DOI:   http://dx.doi.org/10.1073/PNAS.0703137104
 [A]  - FRANCES WISEMAN, "A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome", NATURE REVIEWS NEUROSCIENCE, (20150101), vol. 16, pages 564 - 574, XP055712026 [A] 1-36 *** Fig. 1 ***

DOI:   http://dx.doi.org/10.1038/nrn3983
 [YD]  - PAVEL V. BELICHENKO ET AL, "An Anti-[beta]-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome", PLOS ONE, (20160329), vol. 11, no. 3, doi:10.1371/journal.pone.0152471, page e0152471, XP055711830 [YD] 1-36 *** pages 2, 3 ***

DOI:   http://dx.doi.org/10.1371/journal.pone.0152471
by applicantWO2005081872
 WO2007068411
 WO2012020124
 WO2012055933
 WO2013044147
    - O'BRYANT et al., Arch Neurol., (20100000), vol. 67, no. 6, pages 746 - 749
    - NASREDDINE ZSPHILLIPS NA et al., "The Montreal Cognitive Assessment, MoCA: A brief screening tool for mild cognitive impairment", J Am Geriatr Soc., (20050000), vol. 53, pages 695 - 699
    - BELICHENKO PVMADANI RREY-BELLET L et al., "An Anti-(3-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome", PLOS ONE, (20160000), vol. 11, no. 3, page e0152471
    - FOLSTEIN MFFOLSTEIN SEMCHUGH PR, "Mini-Mental State'': a practical method for grading the cognitive state of patients for the clinician", J Psychiatr Res, (19750000), vol. 12, pages 189 - 198
    - GILMAN S.KOLLER M.BLACK R.S.JENKINS L.GRIFFITH S.G.FOX N.C.EISNER L.KIRBY L., BOADA ROVIRA M.FORETTE F.ORGOGOZO J.M., "Clinical effect of Aβ immunization (AN1792) in patients with AD in an interrupted trial", Neurology, (20050000), vol. 64, doi:10.1212/01.WNL.0000159740.16984.3C, pages 1553 - 1562, XP008103962

DOI:   http://dx.doi.org/10.1212/01.WNL.0000159740.16984.3C
    - HARTLEY SLHANDEN BLDEVENNY D et al., "Cognitive decline and brain amyloid-13 accumulation across 3 years in adults with Down syndrome", Neurobiology of aging, (20170000), vol. 58, pages 68 - 76
    - HEAD EPOWELL DGOLD BTSCHMITT FA., "Alzheimer's Disease in Down Syndrome", European journal of neurodegenerative disease, (20120000), vol. 1, no. 3, pages 353 - 364
    - HUGHES CPBERG LDANZINGER WL et al., "A new clinical scale for the staging of dementia", Am J Psychiatry, (19820000), vol. 140, pages 566 - 572
    - MONSONEGO A.WEINER H.L., "Immunotherapeutic approaches to Alzheimer's disease", Science. 31, (20030000), vol. 302, no. 5646, doi:10.1126/science.1088469, pages 834 - 8, XP002316962

DOI:   http://dx.doi.org/10.1126/science.1088469
    - MUHS A.HICKMAN D.T.PIHLGREN M.CHUARD N.GIRIENS V.MEERSCHMAN C.VAN DER AUWERA I.VAN LEUVEN F.SUGAWARA M.WEINGERTNER M.-C., "Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice", PNAS, (20070000), vol. 104, no. 23, doi:10.1073/PNAS.0703137104, pages 9810 - 9815, XP002542049

DOI:   http://dx.doi.org/10.1073/PNAS.0703137104
    - ORGOGOZO J.M.GILMAN S.DARTIGUES J.F.LAURENT B.PUEL M.KIRBY L.C.JOUANNY P.DUBOIS B.EISNER L.FLITMAN S., "Subacute meningoencephalitis in a subset of patients with AD after Abet42 immunization", Neurology, (20030000), vol. 61, doi:10.1212/01.WNL.0000073623.84147.A8, pages 46 - 54, XP055642773

DOI:   http://dx.doi.org/10.1212/01.WNL.0000073623.84147.A8
    - PRASHER VPHUXLEY AHAQUE MS, "A 24-week, doubleblind, placebo-controlled trial of donepezil in patients with Down syndrome and Alzheimer's disease-pilot study", Int J Geriatr Psychiatry, (20020000), vol. 17, no. 3, pages 270 - 278
    - PIHLGREN M.SILVA A.B.MADANI R.GIRIENS V.WAECKERLE-MEN Y.FETTELSCHOSS A.HICKMAN D.T.LOPEZ-DEBER M.P.NDAO D.M.VUKICEVIC M., "TLR4-and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell-independent isotype switch in mice", Blood, (20130103), vol. 121, no. 1, doi:10.1182/blood-2012-02-413831, pages 85 - 94, XP055552884

DOI:   http://dx.doi.org/10.1182/blood-2012-02-413831
    - SOTO C., "Plaque busters: strategies to inhibit amyloid formation in Alzheimer's disease", Molecular Medicine Today, (19990800), vol. 5, doi:10.1016/S1357-4310(99)01508-7, XP000985704

DOI:   http://dx.doi.org/10.1016/S1357-4310(99)01508-7
    - WINBLAD B.GRAF A.RIVIERE M.E.ANDREASEN N.RYAN J.M., "Active immunotherapy options for Alzheimer's disease", Alzheimers Res Ther., (20140130), vol. 6, no. 1, doi:10.1186/alzrt237, page 7, XP021196286

DOI:   http://dx.doi.org/10.1186/alzrt237
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.