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Extract from the Register of European Patents

EP About this file: EP3950060

EP3950060 - COMPOSITION FOR PROMOTING SECRETION OF EXTRACELLULAR VESICLES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  16.01.2026
Database last updated on 28.02.2026
FormerGrant of patent is intended
Status updated on  26.05.2025
FormerRequest for examination was made
Status updated on  07.01.2022
FormerThe international publication has been made
Status updated on  09.10.2020
Most recent event   Tooltip16.01.2026Application deemed to be withdrawnpublished on 18.02.2026  [2026/08]
Applicant(s)For all designated states
Nissan Chemical Corporation
5-1, Nihonbashi 2-chome
Chuo-ku
Tokyo 103-6119 / JP
For all designated states
National University Corporation Kanazawa University
Nu 7, Kakuma-machi
Kanazawa-shi
Ishikawa 920-1192 / JP
[2022/06]
Inventor(s)01 / MATOBA Kazutaka
c/o Nissan Chemical Corporation, Biological
Research Laboratories, 1470, Shiraoka
Shiraoka-shi, Saitama 349-0294 / JP
02 / KIDA Katsuhiko
c/o Nissan Chemical Corporation, Biological
Research Laboratories, 1470, Shiraoka
Shiraoka-shi, Saitama 349-0294 / JP
03 / NISHINO Taito
c/o Nissan Chemical Corporation, Biological
Research Laboratories, 1470, Shiraoka
Shiraoka-shi, Saitama 349-0294 / JP
04 / HANAYAMA Rikinari
c/o NATIONAL UNIVERSITY CORPORATION KANAZAWA
UNIVERSITY, Nu 7, Kakuma-machi
Kanazawa-shi, Ishikawa 920-1192 / JP
05 / YOSHIDA Takeshi
c/o NATIONAL UNIVERSITY CORPORATION KANAZAWA
UNIVERSITY, Nu 7, Kakuma-machi
Kanazawa-shi, Ishikawa 920-1192 / JP
[N/P]
Former [2022/06]01 / MATOBA Kazutaka
Shiraoka-shi, Saitama 349-0294 / JP
02 / KIDA Katsuhiko
Shiraoka-shi, Saitama 349-0294 / JP
03 / NISHINO Taito
Shiraoka-shi, Saitama 349-0294 / JP
04 / HANAYAMA Rikinari
Kanazawa-shi, Ishikawa 920-1192 / JP
05 / YOSHIDA Takeshi
Kanazawa-shi, Ishikawa 920-1192 / JP
Representative(s)dompatent
Partnerschaft von
Patentanwälten und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
[N/P]
Former [2022/06]dompatent von Kreisler Selting Werner - Partnerschaft von Patent- und Rechtsanwälten mbB
Deichmannhaus am Dom
Bahnhofsvorplatz 1
50667 Köln / DE
Application number, filing date20784669.203.04.2020
[2022/06]
WO2020JP15310
Priority number, dateJP2019007175904.04.2019         Original published format: JP 2019071759
[2022/06]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020204161
Date:08.10.2020
Language:JA
[2020/41]
Type: A1 Application with search report 
No.:EP3950060
Date:09.02.2022
Language:EN
[2022/06]
Search report(s)International search report - published on:JP08.10.2020
(Supplementary) European search report - dispatched on:EP20.03.2023
ClassificationIPC:A61K31/166, A61K31/165, A61K31/11, A61K31/4025, A61K31/05, A61K31/404, A61P25/00, A61P25/14, A61P25/16, A61P25/28, C07C39/14, C07C47/57, C07C235/66, C12N5/0775, C12N1/00, A61K35/28, C07C45/56
[2023/03]
CPC:
C07C45/565 (EP); C12N5/0667 (US); A61K31/05 (EP,US);
A61K31/11 (EP); A61K31/166 (EP); A61K31/4025 (EP);
A61K31/404 (EP); A61K35/28 (EP); A61P25/00 (EP);
A61P25/14 (EP); A61P25/16 (EP); A61P25/28 (EP);
C07C235/66 (EP); C07C39/14 (EP); C07D403/14 (US);
C12N5/0663 (US); C12N5/0665 (US); C12N2501/999 (US) (-)
Former IPC [2022/06]A61P25/00, A61P25/14, A61P25/16, A61P25/28, C07C39/14, C07C47/57, C07C235/66, C12N5/0775, C12N1/00, A61K31/05, A61K31/11, A61K31/165, A61K31/4025, A61K31/404
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/06]
TitleGerman:ZUSAMMENSETZUNG ZUR FÖRDERUNG DER SEKRETION VON EXTRAZELLULÄREN VESIKELN[2022/06]
English:COMPOSITION FOR PROMOTING SECRETION OF EXTRACELLULAR VESICLES[2022/06]
French:COMPOSITION FAVORISANT LA SÉCRÉTION DE VÉSICULES EXTRACELLULAIRES[2022/06]
Entry into regional phase04.10.2021Translation filed 
04.10.2021National basic fee paid 
04.10.2021Search fee paid 
04.10.2021Designation fee(s) paid 
04.10.2021Examination fee paid 
Examination procedure04.10.2021Examination requested  [2022/06]
16.10.2023Amendment by applicant (claims and/or description)
27.05.2025Communication of intention to grant the patent
30.09.2025Application deemed to be withdrawn, date of legal effect  [2026/08]
15.10.2025Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2026/08]
Fees paidRenewal fee
31.03.2022Renewal fee patent year 03
28.03.2023Renewal fee patent year 04
27.03.2024Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.04.202506   M06   Not yet paid
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Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X] US2010189683  (HOLMLUND JON T et al.) [X] 1,3-5,9-10 * page 1, paragraph [0010] * * page 30; claims 1, 2 * * page 11, paragraph [0100] *
 [X] US2009105319  (PELLECCHIA MAURIZIO et al.) [X] 1,3-5,9-11 * page 1, paragraph [0004] * * page 36; claims 28-30 * * page 37; claims 38, 39, 41, 43, 44 * * page 38; claims 52, 53 *
 [X] US2018133212  (BATES JAMIE GEIER et al.) [X] 1,3-5,9-10 * page 75; claims 1, 2 * * pages 80, 81; claims 30-32 *
 [X] US2015335674  (KOTTMANN ROBERT M et al.) [X] 1,3-5,9-11 * page 1, paragraph [0003] * * page 23; claims 1, 5 * * page 15, paragraph [0230] *
 [X] WO0247673  (WACKVOM LTD et al.) [X] 1,3-5,9-11 * page 22; claims 12, 15, 16 *
 [X]   ROGER S. JACKSON ET AL: "Sabutoclax, a Mcl-1 Antagonist, Inhibits Tumorigenesis in Transgenic Mouse and Human Xenograft Models of Prostate Cancer", NEOPLASIA, vol. 14, no. 7, 1 July 2012 (2012-07-01), US, pages 656 - IN24, XP055393537, ISSN: 1476-5586, DOI: 10.1593/neo.12640 [X] 1,4-5,9-11 * abstract * * page 658, column left, paragraph 1st *

DOI:   http://dx.doi.org/10.1593/neo.12640
International search[A] WO2015120150  (STC UNM et al.)
 [A] WO2018011191  (EVOX THERAPEUTICS LTD et al.)
 [A] WO2018102397  (PURETECH HEALTH LLC et al.)
 [A]   YAMASHITA, TATSUYUKI : "Sulfated glycolipid sulfatide promotes exosome secretion in mesenchymal stem cells", JOURNAL OF THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE REGENERATIVE MEDICINE, vol. 16, 1 February 2017 (2017-02-01), JP, pages 367, XP009530871
by applicantJP2011513217
 WO2017022809
 WO2015088288
 JP2018150290
 WO2016167373
   YUYAMA K ET AL., J BIOL CHEM., vol. 289, no. 35, 2014, pages 24488 - 98
   YUYAMA K ET AL., J BIOL CHEM., vol. 287, no. 14, 2012, pages 10977 - 89
   GIEBEL B ET AL., STEM CELL INVESTIG, vol. 4, 24 October 2017 (2017-10-24), pages 84
   NATURE METHODS, vol. 8, 2011, pages 424 - 429
   CAS , no. 1228108-65-3
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.