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Extract from the Register of European Patents

EP About this file: EP3955973

EP3955973 - GENE THERAPIES FOR STARGARDT DISEASE (ABCA4) [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  21.01.2022
Database last updated on 13.09.2024
FormerThe international publication has been made
Status updated on  23.10.2020
Most recent event   Tooltip29.04.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
University of Massachusetts
One Beacon Street
31st Floor
Boston, MA 02108 / US
[2022/08]
Inventor(s)01 / KHANNA, Hemant
159 Dodge Hill Road
Sutton, MA 01590 / US
 [2022/08]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[2022/08]
Application number, filing date20791568.716.04.2020
[2022/08]
WO2020US28504
Priority number, dateUS201962836493P19.04.2019         Original published format: US 201962836493 P
[2022/08]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2020214809
Date:22.10.2020
Language:EN
[2020/43]
Type: A2 Application without search report 
No.:EP3955973
Date:23.02.2022
Language:EN
The application published by WIPO in one of the EPO official languages on 22.10.2020 takes the place of the publication of the European patent application.
[2022/08]
Search report(s)International search report - published on:US19.11.2020
(Supplementary) European search report - dispatched on:EP21.12.2022
ClassificationIPC:A61K48/00, C12N15/861, C12N7/00, C12N15/86
[2022/08]
CPC:
A61K48/0058 (EP,US); C07K14/705 (EP,US); A61K48/0075 (EP);
C12N15/86 (EP,US); C12N2750/14143 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/08]
TitleGerman:GENTHERAPIEN FÜR MORBUS STARGARDT (ABCA4)[2022/08]
English:GENE THERAPIES FOR STARGARDT DISEASE (ABCA4)[2022/08]
French:THÉRAPIES GÉNIQUES POUR LA MALADIE DE STARGARDT (ABCA4)[2022/08]
Entry into regional phase25.10.2021National basic fee paid 
25.10.2021Search fee paid 
25.10.2021Designation fee(s) paid 
25.10.2021Examination fee paid 
Examination procedure25.10.2021Examination requested  [2022/08]
21.07.2023Amendment by applicant (claims and/or description)
Fees paidRenewal fee
27.04.2022Renewal fee patent year 03
27.04.2023Renewal fee patent year 04
29.04.2024Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]US2007042462  (HILDINGER MARKUS [US]) [X] 1-15* example -; claim - *;
 [X]US2015259395  (CHALBERG THOMAS W [US], et al) [X] 1-15 * example -; claim - *;
 [X]WO2018109011  (STICHTING KATHOLIEKE UNIV [NL]) [X] 1-15 * example -; claim - *
International search[A]US2007042462  (HILDINGER MARKUS [US]) [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 * ; Abstract; Paragraphs [0102]-[0106], [0124]; SEQ ID NO: 1 *;
 [A]WO2009134418  (FOX CHASE CANCER CT [US], et al) [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 * ; Abstract; Example 3; Pages 58, 90, Table 1; Page 12, Third Paragraph; SEQ ID NO: 792 *;
 [A]  - SANGERMANO, R et al., "ABCA4 Midigenes Reveal the Full Splice Spectrum of All Reported Noncanonical Splice Site Variants in Stargardt Diseas e", Genome Research, vol. 28, doi:10.1101/gr.226621.117, (20180000), pages 100 - 110, URL: www.genome.org, XP055538937 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 * ; Abstract; Page 107, Right Column, Fourth Paragraph; Page 108, Right Column, Second Paragraph. *

DOI:   http://dx.doi.org/10.1101/gr.226621.117
 [A]  - BAUWENS, M et al., "ABCA4-Associated Disease As A Model for Missing Heritability in Autosomal Recessive Disorders: Novel Noncoding Splice, Cis-regulatory, Structural, and Recurrent Hypomorphic Variants", Genetics in Medicine, (20190123), vol. 21, no. 8, doi:10.1038/s41436-018-0420-y, page 1761, XP036851953 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 * , Abstract; Page 1762, Right Column, Fourth Paragraph to Page 1762, Left Column, First Paragraph; Page 1763, Left Column, Fourth Paragraph to Fifth Paragraph. *

DOI:   http://dx.doi.org/10.1038/s41436-018-0420-y
 [A]  - SCHULZ, HL et al., "Mutation Spectrum of the ABCA4 Gene in 335 Stargardt Disease Patients From A Multicenter German Cohort - Impact of Selected Deep Intronic Variants and Common SNPs", Invest Ophthalmol Vis Sci, (20170100), vol. 58, doi:10.11671 iovs.16-19936, ISSN 1552-5783, pages 394 - 403, XP055487125 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 * ; Page 394, Abstract. *

DOI:   http://dx.doi.org/10.1167/iovs.16-19936
 [A]  - SANGERMANO, R et al., "ABCA4 Midigenes Reveal the Full Splice Spectrum of All Reported Noncanonical Splice Site Variants in Stargardt Disease", Genome Research, vol. 28, doi:10.1101/gr.226621.117, (20180000), pages 100 - 110, URL: www.genome.org, XP055538937 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 * ; Abstract; Page 107, Right Column, Fourth Paragraph; Page 108, RightColumn, Second Paragraph. * [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9

DOI:   http://dx.doi.org/10.1101/gr.226621.117
 [A]  - "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences", PNAS, (20021224), vol. 99, no. 26, doi:10.1073/pnas.242603899, pages 16899 - 16903, XP008125711 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9

DOI:   http://dx.doi.org/10.1073/pnas.242603899
 [A]  - "ABCA4 variant protein [Homo sapiens", GenBank, NCBI, (20150919), Database accession no. BAE06122.2, XP055761000 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9 [A] 1-3, 4/1-3, 5/4/1-3, 7-9, 10/7-9, 11/10/7-9
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.