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EP3976116
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EP About this file: EP3976116
| EP3976116 - LUX EXPRESSION IN CELLS AND METHODS OF USE [Right-click to bookmark this link] | Status | Request for examination was made Status updated on 04.03.2022 Database last updated on 03.09.2024 | |
| Former | The international publication has been made Status updated on 05.12.2020 | Most recent event Tooltip | 14.03.2024 | New entry: Application deemed to be withdrawn: despatch of communication + time limit | Applicant(s) | For all designated states 490 Biotech, Inc. 2450 EJ Chapman Drive Knowville, Tennessee 37996 / US | [2022/14] | Inventor(s) | 01 /
CLOSE, Daniel 6904 Pennell Lane Knoxville, Tennessee 37931 / US | 02 /
RIPP, Steven 2005 Hocotake Lane Knoxville, Tennessee 37921 / US | 03 /
SAYLER, Gary 303 McKinney Road Blaine, Tennessee 37719 / US | 04 /
CONWAY, Michael 200 Woburn Street Medford, Tennessee 02155 / US | [2022/14] | Representative(s) | Mewburn Ellis LLP Aurora Building Counterslip Bristol BS1 6BX / GB | [2022/14] | Application number, filing date | 20812559.1 | 29.05.2020 | [2022/14] | WO2020US35442 | Priority number, date | US201962854758P | 30.05.2019 Original published format: US 201962854758 P | [2022/14] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2020243660 | Date: | 03.12.2020 | Language: | EN | [2020/49] | Type: | A1 Application with search report | No.: | EP3976116 | Date: | 06.04.2022 | Language: | EN | The application published by WIPO in one of the EPO official languages on 03.12.2020 takes the place of the publication of the European patent application. | [2022/14] | Search report(s) | International search report - published on: | US | 03.12.2020 | (Supplementary) European search report - dispatched on: | EP | 24.07.2023 | Classification | IPC: | A61K49/00, C12N5/10, C12Q1/02, G01N33/48, C12Q1/66, C12Q1/68, C07H21/04 | [2022/14] | CPC: |
G01N33/582 (EP);
C12N15/64 (US);
C12N15/65 (EP);
C12N15/85 (US);
C12N5/0607 (US);
C12Q1/02 (EP);
C12Q1/66 (US);
G01N33/5014 (US);
A01K2207/12 (EP);
A01K2227/105 (EP);
A01K2267/0393 (EP);
C12Y105/0103 (EP,US);
C12Y114/14003 (EP,US)
(-)
| C-Set: |
C12N15/65, C12Q2563/103 (EP)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2022/14] | Title | German: | LUX-EXPRESSION IN ZELLEN UND VERFAHREN ZUR VERWENDUNG | [2022/14] | English: | LUX EXPRESSION IN CELLS AND METHODS OF USE | [2022/14] | French: | EXPRESSION DE BIOLUMINESCENCE DANS DES CELLULES ET MÉTHODES D'UTILISATION | [2022/14] | Entry into regional phase | 07.12.2021 | National basic fee paid | 07.12.2021 | Search fee paid | 07.12.2021 | Designation fee(s) paid | 07.12.2021 | Examination fee paid | Examination procedure | 07.12.2021 | Examination requested [2022/14] | 21.10.2022 | Amendment by applicant (claims and/or description) | 13.03.2024 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time | Request for further processing for: | 21.10.2022 | Request for further processing filed | 21.10.2022 | Full payment received (date of receipt of payment) Request granted | 31.10.2022 | Decision despatched | Fees paid | Renewal fee | 07.12.2021 | Renewal fee patent year 03 | 16.05.2023 | Renewal fee patent year 04 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [Y]US2013031644 (RIPP STEVEN A [US], et al) [Y] 1-14 * paragraph [0259]; claims 1-20 *; | [X] - Tingting Xu ET AL, "Autobioluminescent Cellular Models for Enhanced Drug Discovery", Special Topics in Drug Discovery, InTech, (20161130), pages 1 - 26, doi:10.5772/65062, ISBN 978-953-51-2800-7, XP055763086 [X] 1-14 * page 9, paragraph 4; figure 1 * DOI: http://dx.doi.org/10.5772/65062 | [Y] - XU TINGTING ET AL, "Autonomously Bioluminescent Mammalian Cells for Continuous and Real-time Monitoring of Cytotoxicity", JOURNAL OF VISUALIZED EXPERIMENTS, no. 80, doi:10.3791/50972, (20131001), URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995105/pdf/jove-80-50972.pdf, XP093063712 [Y] 1-14 * page 5 * DOI: http://dx.doi.org/10.3791/50972 | [Y] - DAN CLOSE ET AL, "The Evolution of the Bacterial Luciferase Gene Cassette (lux) as a Real-Time Bioreporter", SENSORS, (20120111), vol. 12, no. 1, doi:10.3390/s120100732, pages 732 - 752, XP055647253 [Y] 14 * figure 5; table 1 * DOI: http://dx.doi.org/10.3390/s120100732 | [Y] - TINGTING XU ET AL, "Expression of a Humanized Viral 2A-Mediated lux Operon Efficiently Generates Autonomous Bioluminescence in Human Cells", PLOS ONE, (20140101), vol. 9, no. 5, doi:10.1371/journal.pone.0096347, pages 1 - 11, XP055763090 [Y] 1-14 * page 2, column 2, paragraph 2 * DOI: http://dx.doi.org/10.1371/journal.pone.0096347 | [Y] - DAN M. CLOSE ET AL, "Autonomous Bioluminescent Expression of the Bacterial Luciferase Gene Cassette (lux) in a Mammalian Cell Line", PLOS ONE, (20100827), vol. 5, no. 8, doi:10.1371/journal.pone.0012441, page e12441, XP055202056 [Y] 1-14 * page 2, column 2, paragraph 2; figure 1; table 1 * DOI: http://dx.doi.org/10.1371/journal.pone.0012441 | International search | [X]WO2008144052 (WALIA RAMPYARI [US]) [X] 1 * claims 1-64 *; | [X]US2013031644 (RIPP STEVEN A [US], et al) [X] 1, 1A, 2* claims 1-10 *; | [X] - Xu Tingting, Conway Michael, Frank Ashley, Brumbaugh Amelia, Ripp Steven, Close Dan, "Autobioluminescent Cellular Models for Enhanced Drug Discovery", Special Topics in Drug Discovery 2016, (20161130), vol. 14, no. 15, doi:10.5772/65062, pages 3 , 7 - 9, XP055763086 [X] 1, 1A, 2 DOI: http://dx.doi.org/10.5772/65062 | [X] - Xu Tingting, Ripp Steven, Sayler Gary S., Close Dan M., "Expression of a humanized viral 2A-mediated lux operon efficiently generates autonomous bioluminescence in human cells", PLoS One, (20140000), vol. 9, no. 5, page e96347, XP055763090 [X] 1, 1A, 2 * ; in entirety * DOI: http://dx.doi.org/10.1371/journal.pone.0096347 |