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Extract from the Register of European Patents

EP About this file: EP4019957

EP4019957 - MASS SPECTROMETRY METHOD USING CHROMATOGRAPHY-MASS SPECTROMETRY DEVICE [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  27.05.2022
Database last updated on 24.08.2024
FormerThe international publication has been made
Status updated on  05.12.2020
Most recent event   Tooltip06.07.2024New entry: Additional fee for renewal fee: despatch of communication + time limit 
Applicant(s)For all designated states
Shin Nippon Biomedical Laboratories, Ltd.
2438, Miyanoura-cho Kagoshima-shi
Kagoshima 891-1394 / JP
[2022/26]
Inventor(s)01 / SENDA, Naoto
c/o Shin Nippon Biomedical Laboratories, Ltd.,
2438, Miyanoura-cho
Kagoshima-shi, Kagoshima 891-1394 / JP
02 / TSUKAZAKI, Yasuko
c/o Shin Nippon Biomedical Laboratories, Ltd.,
2438, Miyanoura-cho
Kagoshima-shi, Kagoshima 891-1394 / JP
 [2022/26]
Representative(s)van Dam, Vincent
Octrooibureau Vriesendorp & Gaade B.V.
Koninginnegracht 19
2514 AB Den Haag / NL
[2022/26]
Application number, filing date20813227.421.05.2020
[2022/26]
WO2020JP20150
Priority number, dateJP2019010298831.05.2019         Original published format: JP 2019102988
[2022/26]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020241454
Date:03.12.2020
Language:JA
[2020/49]
Type: A1 Application with search report 
No.:EP4019957
Date:29.06.2022
Language:EN
[2022/26]
Search report(s)International search report - published on:JP03.12.2020
(Supplementary) European search report - dispatched on:EP20.11.2023
ClassificationIPC:G01N27/62, G01N30/72, G01N30/86, G01N30/88
[2022/26]
CPC:
H01J49/005 (EP,CN); G01N30/02 (CN); G01N30/7233 (CN,US);
G01N27/62 (CN); G01N30/34 (CN); G01N30/72 (EP);
G01N30/86 (EP); G01N30/88 (EP); H01J49/0027 (CN);
H01J49/004 (CN); G01N2030/027 (US); G01N2030/8831 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/26]
TitleGerman:MASSENSPEKTROMETRISCHES VERFAHREN MIT CHROMATOGRAFIEMASSENSPEKTROMETER[2022/26]
English:MASS SPECTROMETRY METHOD USING CHROMATOGRAPHY-MASS SPECTROMETRY DEVICE[2022/26]
French:PROCÉDÉ DE SPECTROMÉTRIE DE MASSE UTILISANT UN DISPOSITIF DE SPECTROMÉTRIE DE MASSE PAR CHROMATOGRAPHIE[2022/26]
Entry into regional phase22.11.2021Translation filed 
22.11.2021National basic fee paid 
22.11.2021Search fee paid 
22.11.2021Designation fee(s) paid 
22.11.2021Examination fee paid 
Examination procedure22.11.2021Examination requested  [2022/26]
28.06.2024Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
Fees paidRenewal fee
25.03.2022Renewal fee patent year 03
23.03.2023Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.05.202405   M06   Not yet paid
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]US5397467  (MORGAN NED R [US], et al) [Y] 3 * figure 1 * * column 3, line 7 - line 68 *;
 [A]US2011260051  (PREUDHOMME HUGUES [FR], et al) [A] 7 * paragraph [0099] *;
 [XYI]  - UTA GREIFENHAGEN ET AL, "Sensitive and Site-Specific Identification of Carboxymethylated and Carboxyethylated Peptides in Tryptic Digests of Proteins and Human Plasma", JOURNAL OF PROTEOME RESEARCH, (20150206), vol. 14, no. 2, doi:10.1021/pr500799m, ISSN 1535-3893, pages 768 - 777, XP055259176 [X] 1,4-6 * page 768, column r, paragraph 2 - page 770, column l, paragraph 3 * * page 770, column r, paragraph 2 * * page 769, column r, paragraph 2 - page 770, column l, paragraph 1 * * page 771, column r, paragraph 4 * [Y] 3 [I] 7

DOI:   http://dx.doi.org/10.1021/pr500799m
 [I]  - CHEN BUYUN ET AL, "A One-Step Solid Phase Extraction Method for Bioanalysis of a Phosphorothioate Oligonucleotide and Its 3' n-1 Metabolite from Rat Plasma by uHPLC-MS/MS", THE AAPS JOURNAL, SPRINGER US, BOSTON, (20120728), vol. 14, no. 4, doi:10.1208/S12248-012-9394-X, pages 772 - 780, XP035719312 [I] 1,2 * page 773, column l, paragraph 4 - column r, paragraph 1 *

DOI:   http://dx.doi.org/10.1208/s12248-012-9394-x
 [A]  - HUSSER CHRISTOPHE ET AL, "Identification of GalNAc-Conjugated Antisense Oligonucleotide Metabolites Using an Untargeted and Generic Approach Based on High Resolution Mass Spectrometry", ANALYTICAL CHEMISTRY, US, (20170620), vol. 89, no. 12, doi:10.1021/acs.analchem.7b01244, ISSN 0003-2700, pages 6821 - 6826, XP093098774 [A] 7 * abstract * * page 6823, paragraph 5 *

DOI:   http://dx.doi.org/10.1021/acs.analchem.7b01244
 [A]  - LIU RONG ET AL, "The role of fluoroalcohols as counter anions for ion-pairing reversed-phase liquid chromatography/high-resolution electrospray ionization mass spectrometry analysis of oligonucleotides", RAPID COMMUNICATIONS IN MASS SPECTROMETRY, GB, vol. 33, no. 7, doi:10.1002/rcm.8386, ISSN 0951-4198, (20190415), pages 697 - 709, URL: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Frcm.8386, XP093098967 [A] 1,2 * Rationale and Methods Inset; page 697 *

DOI:   http://dx.doi.org/10.1002/rcm.8386
International search[Y]JP2008521873  (PROSIDION LIMITED) [Y] 1-7 * paragraphs [0065]-[0088] *;
 [Y]JP2016026205  (MALLINCKRODT LLC) [Y] 1-7 * paragraph [0096] *;
 [Y]JP2018040672  (AIST) [Y] 1-7 * claims, paragraph [0004] *;
 [Y]  - "Agilent A-Line safe cap. Prevention performance of vent valve mobile phase volatilization", Application Note, JP, vol. LC-201606WN-001, pages 1 - 2, Application Note, URL: https://www.chem-agilent.com/appnote/pdf/LC-201606WN-001.pdf, (20211203), XP009531905 [Y] 3
by applicantJP2006509214
 WO2016125271
 JP2017215215
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