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Extract from the Register of European Patents

EP About this file: EP3992291

EP3992291 - NOVEL COMPOUND AND APPLICATION THEREOF [Right-click to bookmark this link]
StatusRequest for examination was made
Status updated on  02.04.2022
Database last updated on 11.09.2024
FormerThe international publication has been made
Status updated on  15.01.2021
Most recent event   Tooltip02.04.2024New entry: Renewal fee paid 
Applicant(s)For all designated states
Kylonova (Xiamen) Biopharma Co., Ltd.
CHEN, Qingyan
Room 302, No. 120, Xin Yuan Rd., Haicang District
Xiamen, Fujian 361022 / CN
[2022/18]
Inventor(s)01 / LU, Xueqin
LU, Xueqin Room 302, No. 120, Xin Yuan Rd.,
Haicang District
Xiamen, Fujian 361022 / CN
02 / MU, Zhuo
MU, Zhuo Room 302, No. 120, Xin Yuan Rd., Haicang
District
Xiamen, Fujian 361022 / CN
03 / WANG, Shengjun
WANG, Shengjun Room 302, No. 120, Xin Yuan Rd.,
Haicang District
Xiamen, Fujian 361022 / CN
04 / DU, Yanchun
DU, Yanchun Room 302, No. 120, Xin Yuan Rd.,
Haicang District
Xiamen, Fujian 361022 / CN
 [2022/18]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[2022/18]
Application number, filing date20830838.723.06.2020
[2022/18]
WO2020CN97732
Priority number, dateCN20191057603728.06.2019         Original published format: CN201910576037
CN20191128138913.12.2019         Original published format: CN201911281389
[2022/18]
Filing languageZH
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2020259497
Date:30.12.2020
Language:ZH
[2020/53]
Type: A1 Application with search report 
No.:EP3992291
Date:04.05.2022
Language:EN
[2022/18]
Search report(s)International search report - published on:CN30.12.2020
(Supplementary) European search report - dispatched on:EP04.07.2023
ClassificationIPC:C12N15/113, A61K31/713, A61P1/16
[2022/18]
CPC:
A61P1/16 (EP,CN,KR); C12N15/113 (CN,KR); C12N15/1131 (EP,US);
A61K31/713 (CN,KR); A61K47/545 (US); A61K47/549 (EP);
A61K47/55 (US); A61P31/20 (US); C12N2310/11 (US);
C12N2310/14 (EP,CN,KR,US); C12N2310/31 (CN,KR); C12N2310/351 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2022/18]
TitleGerman:NEUE VERBINDUNG UND ANWENDUNG DAVON[2022/18]
English:NOVEL COMPOUND AND APPLICATION THEREOF[2022/18]
French:NOUVEAU COMPOSÉ ET SON APPLICATION[2022/18]
Entry into regional phase27.01.2022Translation filed 
27.01.2022National basic fee paid 
27.01.2022Search fee paid 
27.01.2022Designation fee(s) paid 
27.01.2022Examination fee paid 
Examination procedure27.01.2022Examination requested  [2022/18]
31.01.2024Amendment by applicant (claims and/or description)
31.01.2024Date on which the examining division has become responsible
Fees paidRenewal fee
27.01.2022Renewal fee patent year 03
31.03.2023Renewal fee patent year 04
31.03.2024Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[Y]WO2009073809  (ALNYLAM PHARMACEUTICALS INC [US], et al) [Y] 1-12 * page 12 - page 20; examples 11,22 * * page 124 - page 125; figures 2,7,11,26,27; claims 1-3,14-16 *;
 [A]WO2016077321  (ALNYLAM PHARMACEUTICALS INC [US]) [A] 1-12 * claims 1-18,58-86; sequences 369,409 *;
 [A]WO2018027106  (ARROWHEAD PHARMACEUTICALS INC [US]) [A] 1-12 * examples 3,4; claims 1-14 *;
 [Y]WO2018185253  (SILENCE THERAPEUTICS GMBH [DE]) [Y] 1-12 * page 75; figures 2,3,5,7-12; claims 1-9,39 *;
 [A]US2018371463  (LIMPHONG PATTRARANEE [US], et al) [A] 1-12 * claims 1-22,33,37; sequences 683,686 *;
 [A]  - JAYAPRAKASH K. NAIR ET AL, "Multivalent N -Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (20141210), vol. 136, no. 49, doi:10.1021/ja505986a, ISSN 0002-7863, pages 16958 - 16961, XP055181463 [A] 1-12 * Scheme 1;; figure 1 *

DOI:   http://dx.doi.org/10.1021/ja505986a
 [A]  - VIVEK K. SHARMA ET AL, "Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo", BIOCONJUGATE CHEMISTRY, US, (20180613), vol. 29, no. 7, doi:10.1021/acs.bioconjchem.8b00365, ISSN 1043-1802, pages 2478 - 2488, XP055556649 [A] 1-12 * figure 1 *

DOI:   http://dx.doi.org/10.1021/acs.bioconjchem.8b00365
 [A]  - WANYI TAI, "Current Aspects of siRNA Bioconjugate for In Vitro and In Vivo Delivery", MOLECULES, (20190613), vol. 24, no. 12, doi:10.3390/molecules24122211, page 2211, XP055636943 [A] 1-12 * figures 2,3 *

DOI:   http://dx.doi.org/10.3390/molecules24122211
International search[A]CN102869774  (HOFFMANN LA ROCHE) [A] 1-12 * entire document *;
 [A]WO2015188194  (ISIS PHARMACEUTICALS INC [US]) [A] 1-12* entire document *;
 [A]WO2017027350  (ARROWHEAD PHARMACEUTICALS INC [US]) [A] 1-12 * entire document *;
 [A]CN106434665  (ARROWHEAD RES CORP) [A] 1-12 * entire document *;
 [Y]CN108064294  (ALNYLAM PHARMACEUTICALS INC) [Y] 1-12 * claims 1, 18 *;
 [Y]CN109331185  (KYLONOVA XIAMEN BIOPHARMA CO LTD) [Y] 1-12 * claims 1-5, 8-16 *;
 [PX]CN110218728  (KYLONOVA XIAMEN BIOPHARMA CO LTD) [PX] 1-12 * entire document *;
 [PX]CN110846320  (KYLONOVA XIAMEN BIOPHARMA CO LTD) [PX] 1-12 * claims 1-12 *
by applicant   - ASHWELL GSHARFORD J, "Carbohydrate specific Receptors of the Liver", Ann Rev Biochem, (19820000), vol. 51, pages 531 - 554
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.